Antioxidants but not doxycycline treatments restore depressed beta-adrenergic responses of the heart in diabetic rats

Cardiovascular Toxicology

Volumn 9, Issue 1, 2009, Pages 21-29

  Bilginoglu, Ayca ^a   Seymen, Aytac ^a   Tuncay, Erkan ^a   Zeydanli, Esma ^a   Aydemir Koksoy, Aslihan ^a   Turan, Belma ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Adrenergic signaling; Antioxidants; Cardiomyopathy; Diabetic; Matrix metalloproteinases

Indexed keywords

ADENYLATE CYCLASE; ALPHA TOCOPHEROL; BETA ADRENERGIC RECEPTOR; DOXYCYCLINE; FATTY ACID; FREEFLOW; GLUCOSE; ISOPRENALINE; MATRIX METALLOPROTEINASE; SELENATE; UNCLASSIFIED DRUG; ANTIOXIDANT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; GELATINASE A; MMP2 PROTEIN, RAT; OMEGA 3 FATTY ACID; PROTEINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SELENIUM DERIVATIVE;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DEPRESSION; DIABETES MELLITUS; DRUG EFFICACY; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HEART FUNCTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CELL; IN VIVO STUDY; INOTROPISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION; TREATMENT DURATION; ANIMAL; CARDIOMYOPATHY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART VENTRICLE PRESSURE; METABOLISM; PATHOPHYSIOLOGY; WISTAR RAT;

ANIMALIA; RATTUS;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; ANIMALS; ANTIOXIDANTS; CARDIOMYOPATHIES; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXYCYCLINE; FATTY ACIDS, OMEGA-3; ISOPROTERENOL; MALE; MATRIX METALLOPROTEINASE 2; MYOCARDIUM; PROTEASE INHIBITORS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTORS, ADRENERGIC, BETA; SELENIUM COMPOUNDS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 66849132167     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12012-009-9032-8     Document Type: Article

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