An increase in serum retinol-binding protein 4 in the type 2 diabetic subjects with nephropathy

Endocrine Journal

Volumn 56, Issue 2, 2009, Pages 287-294

  Murata, Miho ^a   Saito, Tomoyuki ^a   Otani, Taeko ^a   Sasaki, Masami ^a   Ikoma, Aki ^a   Toyoshima, Hideo ^a   Kawakami, Masanobu ^a   Ishikawa, San E ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Albuminuria; Diabetes mellitus; Diabetic nephropathy; Estimated gfr; RBP4

Indexed keywords

CREATININE; RETINOL BINDING PROTEIN 4;

ADULT; AGED; ALBUMINURIA; ARTICLE; ATHEROSCLEROTIC CARDIOVASCULAR DISEASE; CLINICAL FEATURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PROTEIN BLOOD LEVEL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALBUMINURIA; CREATININE; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; MALE; MIDDLE AGED; REGRESSION ANALYSIS; RETINOL-BINDING PROTEINS, PLASMA;

EID: 66849091891     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K08E-242     Document Type: Article

References (28)

1. Soprano DR, Soprano KJ, Goodman DS (1986) Retin- ol-binding protein messenger RNA levels in the liver and in extrahepatic tissues of the rat. J Lipid Res 27: 166-171.
2. Blomhoff R, Green MH, Green JB, Berg T, Norum KR (1991) Vitamin A metabolism: new perspectives on absorption, transport, and storage. Physiol Rev 71: 951-990.
3. Blaner WS (1989) Retinol-binding protein: The serum transport protein for vitamin A. Endocr Rev 10: 308-316.
4. Graham TE, Yang Q, Bluher M, Hammarstedt A, Ciaraldi TP, Henry RR, Wason CJ, Oberbach A, Jansson PA, Smith U, Kahn BB (2006) Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Engl J Med 354: 2552-2563.
5. Janke J, Engeli S, Boschmann M, Adams F, Bohnke J, Luft FC, Sharma AM, Jordan J (2006) Retinol-binding protein 4 in human obesity. Diabetes 55: 2805-2810.
6. Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, Kotani K, Quadro L, Kahn BB (2005) Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 436: 356-362.
7. Mody N, Graham T, Tsuji Y, Yang Q, Kahn BB (2008) Decreased clearance of serum retinol binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice. Am J Physiol Endocrinol Metab 294: E785-E793.
8. Stefan N, Hennige AM, Staiger H, Schleicher E, Fritsche A, Haring HU (2007) Circulating retinol- binding protein-4, insulin sensitivity, insulin secretion, and insulin disposition index in obese and nonobese subjects: response to Broch et al. Diabetes Care 30:e91; author reply e92.
9. Promintzer M, Krebs M, Todoric J, Luger A, Bischof MG, Nowotny P, Wagner O, Esterbauer H, Anderwald C (2007) Insulin resistance is unrelated to circulating retinol binding protein and protein C inhibitor. J Clin Endocrinol Metab 92: 4306-4312.
10. Lewis JG, Shand BI, Elder PA, Scott RS (2008) Plasma retinol-binding protein is unlikely to be a useful marker of insulin resistance. Diabetes Res Clin Pract 80: e13- e15.
11. Yao-Borengasser A, Varma V, Bodles AM, Rasouli N, Phanavanh B, Lee MJ, Starks T, Kern LM, Spencer HJ 3rd, Rashidi AA, McGehee RE Jr, Fried SK, Kern PA (2007) Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. J Clin Endocrinol Metab 92: 2590-2597.
12. Bajzova M, Kovacikova M, Vitkova M, Klimcakova E, Polak J, Kovacova Z, Viguerie N, Vedral T, Mikulasek L, Sramkova P, Srp A, Hejnova J, Langin D, Stich V. Retinol -binding protein 4 expression in visceral and subcutaneous fat in human obesity. Physiol Res 2007 Nov 30 (Epub ahead of print).
13. von Eynatten M, Lepper PM, Liu D, Lang K, Baumann M, Nawroth PP, Bierhaus A, Dugi KA, Heemann U, Allolio B, Humpert PM (2007) Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease. Diabetologia 50: 1930-1937.
14. Raila J, Henze A, Spranger J, Mohlig M, Pfeiffer AF, Schweigert FJ (2007) Microalbuminuria is a major determinant of elevated plasma retinol-binding protein 4 in type 2 diabetic patients. Kidney Int 72: 505-511.
15. Takebayashi K, Suetsugu M, Wakabayashi S, Aso Y, Inukai T (2007) Retinol binding protein-4 levels and clinical features of type 2 diabetes patients. J Clin Endocrinol Metab 92: 2712-2719.
16. Cabre A, Lazaro I, Girona J, Manzanares J, Marimon F, Plana N, Heras M, Masana L (2007) Retinol-binding protein 4 as a plasma biomarker of renal dysfunction and cardiovascular disease in type 2 diabetes. J Intern Med 262:496-503.
17. Ouchi N, Kihara S, Arita Y, Maeda K, Kuriyama H, Okamoto Y, Hotta K, Nishida M, Takahashi M, Nakamura T, Yamashita S, Funahashi T, Matsuzawa Y (1999) Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 100:2473-2476.
18. Ouchi N, Kihara S, Arita Y, Nishida M, Matsuyama A, Okamoto Y, Ishigami M, Kuriyama H, Kishida K, Nishizawa H, Hotta K, Muraguchi M, Ohmoto Y, Yamashita S, Funahashi T, Matsuzawa Y (2001) Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 103: 1057-1063.
19. Okamoto Y, Arita Y, Nishida M, Muraguchi M, Ouchi N, Takahashi M, Igura T, Inui Y, Kihara S, Nakamura T, Yamashita S, Miyagawa J, Funahashi T, Matsuzawa Y (2000) An adipocyte-derived plasma protein, adipo- nectin, adheres to injured vascular walls. Horm Metab Res 32: 47-50.
20. Arita Y, Kihara S, Ouchi N, Maeda K, Kuriyama H, Okamoto Y, Kumada M, Hotta K, Nishida M, Takahashi M, Nakamura T, Shimomura I, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y (2002) Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation 105: 2893-2898.
21. Yokota T, Oritani K, Takahashi I, Ishikawa J, Matsuyama A, Ouchi N, Kihara S, Funahashi T, Tenner AJ, Tomiyama Y, Matsuzawa Y (2000) Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 96: 1723-1732.
22. Matsuda M, Shimomura I, Sata M, Arita Y, Nishida M, Maeda N, Kumada M, Okamoto Y, Nagaretani H, Nishizawa H, Kishida K, Komuro R, Ouchi N, Kihara S, Nagai R, Funahashi T, Matsuzawa Y (2002) Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem 277: 37487-37491.
23. The research committee of diabetic nephropathy (2001) the renewal of classification by Research Committee of the Japanese Ministry of Health, Labor and Welfare for Disorders of diabetes mellitus. J Jpn Diab Soc 44: 623.
24. Ziegelmeier M, Bachmann A, Seeger J, Lossner U, Kratzsch J, Bluher M, Stumvoll M, Fasshauer M (2007) Serum levels of adipokine retinol-binding protein-4 in relation to renal function. Diabetes Care 30: 2588-2592.
25. Goodman DS (1984) Plasma retinol-binding protein. In: Sporn MB, Roberts AB, Goodman DS (eds) The Retinoids, (Vol 2), Academic Press: Orlando, FL, pp. 41-88.
26. Green MH, Green JB (1994) Dynamics and control of plasma retinol. In: Blomhoff R (ed). Vitamin A in Health and Disease. Marcel Dekker: New York, Basel, Hong Kong, pp 199-133.
27. Smith FR, Goodman DS (1971) The effects of diseases of the liver, thyroid, and kidneys on the transport of vitamin A in human plasma. J Clin Invest 50: 2426-2436.
28. Vahlquist A, Peterson PA, Wibell L (1973) Metabolism of the vitamin A transporting protein complex. I. Turnover studies in normal persons and in patients with chronic renal failure. Eur J Clin Invest 3: 352-362.