μ-opioid receptor cell surface expression is regulated by its direct interaction with Ribophorin I

Molecular Pharmacology

Volumn 75, Issue 6, 2009, Pages 1307-1316

  Ge, Xin ^a   Loh, Horace H ^a   Law, Ping Yee ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALNEXIN; DELTA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; MUTANT PROTEIN; RIBOPHORIN I; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE DELETION; GENE OVEREXPRESSION; INTRACELLULAR SPACE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; PROTEOMICS; TANDEM MASS SPECTROMETRY;

ANIMALS; CALNEXIN; CELL LINE, TUMOR; CELL MEMBRANE; ENDOPLASMIC RETICULUM; GENE KNOCKDOWN TECHNIQUES; GLYCOSYLATION; MEMBRANE PROTEINS; MICE; MOLECULAR CHAPERONES; MUTATION; PROTEIN TRANSPORT; RATS; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU;

EID: 66849091680     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.108.054064     Document Type: Article

References (38)

1. Abeijon C and Hirschberg CB (1992) Topography of glycosylation reactions in the endoplasmic reticulum. Trends Biochem Sci 17:32-36.
2. Alder NN and Johnson AE (2004) Cotranslational membrane protein biogenesis at the endoplasmic reticulum. J Biol Chem 279:22787-22790. (Pubitemid 38685576)
3. Alder NN, Shen Y, Brodsky JL, Hendershot LM, and Johnson AE (2005) The molecular mechanisms underlying BiP-mediated gating of the Sec61 translocon of the endoplasmic reticulum. J Cell Biol 168:389-399. (Pubitemid 40205062)
4. Bergman LW and Kuehl WM (1979a) Co-translational modification of nascent immunoglobulin heavy and light chains. J Supramol Struct 11:9-24.
5. Bergman LW and Kuehl WM (1979b) Formation of intermolecular disulfide bonds on nascent immunoglobulin polypeptides. J Biol Chem 254:5690-5694. (Pubitemid 9245803)
6. Chaipatikul V, Erickson-Herbrandson LJ, Loh HH, and Law PY (2003) Rescuing the traffic-deficient mutants of rat μ-opioid receptors with hydrophobic ligands. Mol Pharmacol 64:32-41. (Pubitemid 36759815)
7. Chen C, Li JG, Chen Y, Huang P, Wang Y, and Liu-Chen LY (2006) GEC1 interacts with the κ opioid receptor and enhances expression of the receptor. J Biol Chem 281:7983-7993. (Pubitemid 43847416)
8. Chen W, Helenius J, Braakman I, and Helenius A (1995) Cotranslational folding and calnexin binding during glycoprotein synthesis. Proc Natl Acad Sci U S A 92:6229-6233.
9. Chen Y, Mestek A, Liu J, Hurley JA, and Yu L (1993) Molecular cloning and functional expression of a μ-opioid receptor from rat brain. Mol Pharmacol 44:8-12. (Pubitemid 23230453)
10. de Virgilio M, Weninger H, and Ivessa NE (1998) Ubiquitination is required for the retro-translocation of a short-lived luminal endoplasmic reticulum glycoprotein to the cytosol for degradation by the proteasome. J Biol Chem 273:9734-9743. (Pubitemid 28183065)
11. Doms RW (1990) Oligomerization and protein transport. Methods Enzymol 191:841-854.
12. Dong C and Wu G (2006) Regulation of anterograde transport of α2-adrenergic receptors by the N termini at multiple intracellular compartments. J Biol Chem 281:38543-38554. (Pubitemid 46041979)
13. Evans CJ, Keith DE Jr, Morrison H, Magendzo K, and Edwards RH (1992) Cloning of a delta opioid receptor by functional expression. Science 258:1952-1955. (Pubitemid 23026738)
14. Fu J, Ren M, and Kreibich G (1997) Interactions among subunits of the oligosaccharyltransferase complex. J Biol Chem 272:29687-29692. (Pubitemid 27508061)
15. Hebert DN, Foellmer B, and Helenius A (1996) Calnexin and calreticulin promote folding, delay oligomerization and suppress degradation of influenza hemagglutinin in microsomes. EMBO J 15:2961-2968. (Pubitemid 26187744)
16. Helenius A and Aebi M (2001) Intracellular functions of N-linked glycans. Science 291:2364-2369. (Pubitemid 32231791)
17. Hendershot LM (2004) The ER function BiP is a master regulator of ER function. Mt Sinai J Med 71:289-297.
18. Hurtley SM and Helenius A (1989) Protein oligomerization in the endoplasmic reticulum. Annu Rev Cell Biol 5:277-307. (Pubitemid 19286686)
19. Kapphahn RJ, Ethen CM, Peters EA, Higgins L, and Ferrington DA (2003) Modified alpha A crystallin in the retina: altered expression and truncation with aging. Biochemistry 42:15310-15325. (Pubitemid 38031730)
20. Kelleher DJ and Gilmore R (1997) DAD1, the defender against apoptotic cell death, is a subunit of the mammalian oligosaccharyltransferase. Proc Natl Acad Sci U S A 94:4994-4999. (Pubitemid 27214724)
21. Kelleher DJ, Kreibich G, and Gilmore R (1992) Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd protein. Cell 69:55-65.
22. Kieffer BL, Befort K, Gaveriaux-Ruff C, and Hirth CG (1992) The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc Natl Acad Sci U S A 89:12048-12052. (Pubitemid 23004782)
23. Kornfeld R and Kornfeld S (1985) Assembly of asparagine-linked oligosaccharides. Annu Rev Biochem 54:631-664. (Pubitemid 15073660)
24. Kreibich G, Freienstein CM, Pereyra BN, Ulrich BL, and Sabatini DD (1978) Proteins of rough microsomal membranes related to ribosome binding. II. Crosslinking of bound ribosomes to specific membrane proteins exposed at the binding sites. J Cell Biol 77:488-506. (Pubitemid 8333467)
25. Kreibich G, Sabatini DD, and Adesnik M (1983) Biosynthesis of hepatocyte endoplasmic reticulum proteins. Methods Enzymol 96:530-542.
26. Law PY, Erickson-Herbrandson LJ, Zha QQ, Solberg J, Chu J, Sarre A, and Loh HH (2005) Heterodimerization of μ- and 32 δ-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions. J Biol Chem 280:11152-11164. (Pubitemid 40418422)
27. Lecomte FJ, Ismail N, and High S (2003) Making membrane proteins at the mammalian endoplasmic reticulum. Biochem Soc Trans 31:1248-1252. (Pubitemid 38030948)
28. Morello JP, Salahpour A, Petäjä-Repo UE, Laperrière A, Lonergan M, Arthus MF, Nabi IR, Bichet DG, and Bouvier M (2001) Association of calnexin with wild type and mutant AVPR2 that causes nephrogenic diabetes insipidus. Biochemistry 40:6766-6775. (Pubitemid 32538222)
29. Parodi AJ (2000) Protein glucosylation and its role in protein folding. Annu Rev Biochem 69:69-93.
30. Petaja-Repo UE, Hogue M, Laperriere A, Walker P, and Bouvier M (2000) Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human δ opioid receptor. J Biol Chem275:13727-13736. (Pubitemid 30257444)
31. Robert J, Auzan C, Ventura MA, and Clauser E (2005) Mechanisms of cell-surface rerouting of an endoplasmic reticulum-retained mutant of the vasopressin V1b/V3 receptor by a pharmacological chaperone. J Biol Chem 280:42198-42206. (Pubitemid 43023190)
32. Santhamma KR and Sen I (2000) Specific cellular proteins associate with angiotensin-converting enzyme and regulate its intracellular transport and cleavagesecretion. J Biol Chem 275:23253-23258. (Pubitemid 30646224)
33. Shibatani T, David LL, McCormack AL, Frueh K, and Skach WR (2005) Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits. Biochemistry 44:5982-5992. (Pubitemid 40570692)
34. Shilov IV, Seymour SL, Patel AA, Loboda A, Tang WH, Keating SP, Hunter CL, Nuwaysir LM, and Schaeffer DA (2007). The Paragon Algorithm: a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra. Mol Cell Proteomics 6:1638-1655. (Pubitemid 47506173)
35. Silberstein S and Gilmore R (1996) Biochemistry, molecular biology, and genetics of the oligosaccharyltransferase. FASEB J 10:849-858. (Pubitemid 26186120)
36. Wilson CM and High S (2007) Ribophorin I acts as a substrate-specific facilitator of N-glycosylation. J Cell Sci 120:648-657. (Pubitemid 46437899)
37. Wilson CM, Kraft C, Duggan C, Ismail N, Crawshaw SG, and High S (2005) Ribophorin I associates with a subset of membrane proteins after their integration at the sec61 translocon. J Biol Chem 280:4195-4206. (Pubitemid 40288585)
38. Yu YH, Sabatini DD, and Kreibich G (1990) Antiribophorin antibodies inhibit the targeting to the ER membrane of ribosomes containing nascent secretory polypeptides. J Cell Biol 111:1335-1342. (Pubitemid 120027108)