Association of polymorphisms in thromboxane A2 receptor and thromboxane A synthase 1 with cerebral infarction in a Korean population

BMB Reports

Volumn 42, Issue 4, 2009, Pages 200-205

  Park, Sun Ah ^a   Park, Byung Lae ^b   Park, Jeong Ho ^a   Lee, Tae Kyeong ^a   Sung, Ki Bum ^a   Lee, You Kyoung ^a   Chang, Hun Soo ^c   Park, Choon Sik ^c   Shin, Hyoung Doo ^b,d  

^a Soonchunhyang University   (South Korea)

^b SNP Genetics Inc   (South Korea)

^c Department of Internal Medicine   (South Korea)

^d Sogang University   (South Korea)

Author keywords

Atherosclerosis; Infarction; Polymorphism; Risk factor; Thromboxane A2

Indexed keywords

THROMBOXANE A2 RECEPTOR; THROMBOXANE SYNTHASE;

AGED; ARTICLE; ASIAN; BRAIN INFARCTION; FEMALE; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; KOREA; MALE; MIDDLE AGED; PATHOLOGY;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CEREBRAL INFARCTION; FEMALE; GENOTYPE; HUMANS; KOREA; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; THROMBOXANE-A SYNTHASE;

EID: 66849091429     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2009.42.4.200     Document Type: Article

References (34)

1. th century. Lancet Neurol. 2, 43-53.
2. Liao, D., Myers, R., Hunt, S., Shahar, E., Paton, C., Burke, G., Province, M. and Heiss, G. (1997) Familial history of stroke and stroke risk. The family heart study. Stroke 28, 1908-1912.
3. Pezzini, A., Grassi, M., Del Zotto, E., Archetti, S., Spezi, R., Vergani, V., Assanelli, D., Caimi, L. and Padovani, A. (2005) Cumulative effect of predisposing genotypes and their interaction with modifiable factors on the risk of ischemic stroke in young adults. Stroke 36, 533-539.
4. Hassan, A. and Markus, H. S. (1988) Genetics and ischemic stroke. Brain 123, 1784-1812.
5. Mehta, J. L., Lawson, D., Mehta, P. and Saldeen, T. (1988) Increased prostacyclin and thromboxane A2 biosynthesis in atherosclerosis. Proc. Natl. Acad. Sci. U.S.A. 85, 4511-4515.
6. Koudstaal, P. J., Ciabattoni, G., van Gijn, J., Nieuwenhuis, H. K., de Groot, P. G., Sixma, J. J. and Patrono, C. (1993) Increased thromboxane biosynthesis in patients with acute cerebral ischemia. Stroke 24, 219-223.
7. Preston, F. E., Whipps, S., Jackson, C. A., French, A. J., Wyld, P. J. and Stoddard, C. J. (1981) Inhibition of prostacyclin and platelet thromboxane A2 after low-dose aspirin. N. Engl. J. Med. 304, 76-79.
8. Weksler, B. B., Kent, J. L., Rudolph, D., Scherer, P. B. and Levy, D. E. (1985) Effects of low dose aspirin on platelet function in patients with recent cerebral ischemia. Stroke 16, 5-9.
9. Antiplatelet Trialists' Collaboration (1988) Secondary prevention of vascular disease by prolonged anti-platelet therapy. Br. Med. J. 296, 320-331.
10. Chen, S. T., Hsu, C. Y., Hogan, E. L., Halushka, P. V., Linet, O. I. and Yatsu, F. M. (1986) Thromboxane, prostacyclin, and leukotrienes in cerebral ischemia. Neurology 36, 466-470.
11. Hirata, T., Kakizuka, A., Ushikubi, F., Fuse, I., Okuma, M. and Narumiya, S. (1994) Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorder. J. Clin. Invest. 94, 1662-1667.
12. Cheng, Y., Austin, S. C., Rocca, B., Koller, B. H., Coffman, T. M., Grosser, T., Lawson, J. A. and FitzGerald, G. A. (2002) Role of prostacyclin in the cardiovascular response to thromboxane A2. Science 296, 539-541.
13. Tsujita, Y., Kinoshita, M., Tanabe, T. and Iwai, N. (2000) Role of a genetic variation in the promoter of human thromboxane synthase gene in myocardial infarction. Atherosclerosis 153, 261-262.
14. Unoki, M., Furuta, S., Onouchi, Y., Watanabe, O., Doi, S., Fujiwara, H., Miyatake, A., Fujita, K., Tamari, M. and Nakamura, Y. (2000) Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene. Hum. Genet. 106, 440-446.
15. Shin, H. D., Park, B. L., Jung, J. H., Wang, H. J., Park, H. S., Choi, B. W., Hong, S. J., Lee, Y. M., Kim, Y. H. and Park, C. S. (2003) Association of thromboxane A2 receptor (TBXA2R) with atopy and asthma. J. Allergy. Clin. Immunol. 112, 454-457.
16. Kaneko, Y., Nakayama, T., Saito, K., Morita, A., Sato, I., Maruyama, A., Soma, M., Takahashi, T. and Sato, N. (2006) Relationship between the thromboxane A2 receptor gene and susceptibility to cerebral infarction. Hypertens. Res. 29, 665-671.
17. Moncada, S. and Vance, J. R. (1978) Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2 and prostacyclin. Pharmacol. Rev. 30, 293-331.
18. Dogne, J. M., Hanson, J., de Leval, X., Pratico, D., Pace-Asciak, C.R., Drion, P., Pirotte, B. and Ruan, K. H. (2006) From the design to the clinical application of thromboxane modulator. Curr. Pharm. Design 12, 903-923.
19. Imamura, T., Kiguchi, S., Kobayashi, K., Ichkawa, K., Yamazaki, Y. and Kojima, M. (2003) Effect of ozagrel, a selective thromboxane A2-synthase inhibitor, on cerebral infarction in rats. Comparative study with norphenazone, a free radical scavenger. Arzneimittelforschung. 53, 688-694.
20. rd. (1993) Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in acute stroke treatment. Stroke 24, 35-41.
21. Bamford, J., Sandercock, P., Dennis, M., Burn, J. and Warlow, C. (1991) Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet. 337, 1521-1526.
22. North American Symptomatic Carotid Endarterectomy Trial Collaborators (1991) Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N. Eng. J. Med. 325, 445-453.
23. Fisher, C. M. (1968) The arterial lesions underlying lacunes. Acta. Neuropathol (Berl). 12, 1-15.
24. Mohr, J. P. and Marti-Vilalta, J. L. (1998) Lacunes; in Stroke pathophysiology, diagnosis, and management, Barnett H. J. M., Mohr J. P., Stein B. M. and Yatu F. M. (eds), pp. 599-622, Churchill Livingstone, New York, USA.
25. Hendra, T. and Betteridge, D. J. (1989) Platelet function, platelet prostanoids and vascular prostacyclin in diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids 35, 197-212.
26. Moreno, A., De La Cruz, J. P., Garcia Campos, J. M. and Sanchez de la Custa, F. (1995) Prostacyclin-thromboxane balance and retinal vascular pattern in rats with experimentally induced diabetes. Can. J. Ophthalmol. 30, 117-123.
27. Oishi, M., Mochizuki, Y., Hara, M., Yoshihashi, H. and Takasu, T. (1996) Effects of sodium ozagrel on hemostatic markers and cerebral blood flow in lacunar infarction. Clin. Neuropharmacol. 19, 526-531.
28. Lastilla, M. (2006) Lacunar infarct. Clin. Exp. Hypertens. 28, 205-215.
29. Hulley, S. B. (1988) The US National Cholsterol Education Program. Adult treatment guidelines. Drugs 36 (Suppl. 3), 100-104.
30. Kim, S. H., Choi, J. H., Park, H. S., Holloway, J. W., Lee, S. K., Park, C. S. and Shin, H. D. (2005) Association of thromboxane A2 receptor gene polymorphism with the phenotype of acetylsalicylic acid-intolerant asthma. Clin. Exp. Allergy 35, 585-590.
31. Livak, K. J. (1999) Allelic discrimination using fluorogenic probes and the 5' nuclease assay. Genet. Anal. 14, 143-149.
32. Barrett, J. C., Fry, B., Maller, J. and Daly, M. J. (2005) Haploview: analysis and visualization of LD and halotype maps. Bioinformatics 21, 263-265.
33. Stephens, M., Smith, N. J. and Donnelly, P. (2001) A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68, 978-989.
34. Nyholt, D. R. (2004) A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am. J. Hum. Genet. 74, 765-769.