Early oxygen uptake recovery following exercise testing in children with chronic chest diseases

Pediatric Pulmonology

Volumn 44, Issue 5, 2009, Pages 480-488

  Stevens, D ^a   Oades, P J ^b   Armstrong, N ^a   Williams, C A ^a  

^a UNIVERSITY OF EXETER   (United Kingdom)

^b ROYAL DEVON AND EXETER NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Children; Chronic chest diseases; Clinical measure; Exercise testing; Recovery

Indexed keywords

AEROBIC EXERCISE; ARTICLE; BICYCLE ERGOMETER; CARDIOPULMONARY EXERCISE TEST; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FIBROSIS; LUNG FUNCTION TEST; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROGNOSIS; SCHOOL CHILD; SCORING SYSTEM; SPIROMETRY; THORAX DISEASE;

ADOLESCENT; BRONCHIECTASIS; CASE-CONTROL STUDIES; CHILD; CYSTIC FIBROSIS; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HUMANS; MALE; OXYGEN CONSUMPTION; PULMONARY VENTILATION;

EID: 66749185852     PISSN: 87556863     EISSN: 10990496     Source Type: Journal    
DOI: 10.1002/ppul.21024     Document Type: Article

References (67)

1. Palange P, Ward SA, Carlsen KH, Casaburi R, Gallagher CG, Gosselink R, O'Donnell DE, Puente-Maestu L, Schols AM, Singh S, Whipp BJ. Recommendations on the use of exercise testing in clinical practice. Eur Respir J 2007;29:185 -209.
2. Anthonisen NR, Wright EC, Hodgkin JE. Prognosis in chronic obstructive pulmonary disease. Am Rev Respir Dis 1986;133:14-20.
3. Swaminathan S, Kuppurao KV, Somu N, Vijayan VK. Reduced exercise capacity in non-cystic fibrosis bronchiectasis. Indian J Pediatr 2003;70:553 -556.
4. Edwards EA, Narang I, Li A, Hansell DM, Rosenthal M, Bush A. HRCT lung abnormalities are not a surrogate for exercise limitation in bronchiectasis. Eur Respir J 2004;24:538-544.
5. Kerem E, Reisman J, Corey M, Canny GJ, Levison H. Prediction of mortality in patients with cystic fibrosis. N Engl J Med 1992; 326:1187 -1191.
6. Webb AK, Dodd ME, Moorcroft J. Exercise and cystic fibrosis. J RSoc Med 1995;88:30-36.
7. Orenstein DM. Exercise testing in cystic fibrosis. Pediatr Pulmonol 1998;25:223 -225.
8. Shah AR, Gozal D, Keens TG. Determinants of aerobic and anaerobic exercise performance in cystic fibrosis. Am J Respir Crit Care Med 1998;157:1145-1150.
9. Nixon PA, Orenstein DM, Kelsey SF, Doershuk CF. The prognostic value of exercise testing in patients with cystic fibrosis. N Engl J Med 1992;327:1785-1788.
10. Orenstein DM, Nixon PA, Ross EA, Kaplan RM. The quality of well-being in cystic fibrosis. Chest 1989;95:344-347.
11. Pianosi P, Leblanc J, Almudevar A. Peak oxygen uptake and mortality in children with cystic fibrosis. Thorax 2005;60:50-54.
12. Stevens D, Williams CA. Exercise testing and training with the young Cystic fibrosis patient. J Sports Sci Med 2007;6:286-291.
13. Mahler M. First-order kinetics of muscle oxygen consumption, and an equivalent proportionality between QO2 and phosphor-ylcreatine level. Implications for the control of respiration. J Gen Physiol 1985;86:135-165.
14. Meyer RA. A linear model of muscle respiration explains monoexponential phosphocreatine changes. Am J Physiol 1988;254:C548-C553.
15. Harris RC, Edwards RH, Hultman E, Nordesjo LO, Nylind B, Sahlin K. The time course of phosphorylcreatine resynthesis during recovery of the quadriceps muscle in man. Pflugers Arch 1976;367:137 -142.
16. Sahlin K, Harris RC, Hultman E. Resynthesis of creatine phosphate in human muscle after exercise in relation to intramuscular pH and availability of oxygen. Scand J Clin Lab Invest 1979;39:551 -558.
17. Taylor DJ, Bore PJ, Styles P, Gadian DG, Radda GK. Bioenergetics of intact human muscle. A 31P nuclear magnetic resonance study. Mol Biol Med 1983;1:77-94.
18. Quistorff B, Johansen L, Sahlin K. Absence of phosphocreatine resynthesis in human calf muscle during ischaemic recovery. Biochem J 1993;291:681-686.
19. McMahon S, Jenkins D. Factors affecting the rate of phosphoc- reatine resynthesis following intense exercise. Sports Med 2002; 32:761-784.
20. Chick TW, Cagle TG, Vegas FA, Poliner JK, Murata GH. Recovery of gas exchange variables and heart rate after maximal exercise in COPD. Chest 1990;97:276-279.
21. Kutsuzawa T, Shioya S, Kurita D, Haida M, Ohta Y, Yamabayashi H. 31P-NMR study of skeletal muscle metabolism in patients with chronic respiratory impairment. Am Rev Respir Dis 1992;146:1019-1024.
22. Massie BM, Conway M, Yonge R, Frostick S, Sleight P, Ledingham J, Radda G, Rajagopalan B. 31P nuclear magnetic resonance evidence of abnormal skeletal muscle metabolism in patients with congestive heart failure. Am J Cardiol 1987;60:309-315.
23. Mancini DM, Ferraro N, Tuchler M, Chance B, Wilson JR. Detection of abnormal calf muscle metabolism in patients with heart failure using phosphorus-31 nuclear magnetic resonance. Am J Cardiol 1988;62:1234-1240.
24. Chati Z, Zannad F, Robin-Lherbier B, Escanye JM, Jeandel C, Robert J, Aliot E. Contribution of specific skeletal muscle metabolic abnormalities to limitation of exercise capacity in patients with chronic heart failure: a phosphorus 31 nuclear magnetic resonance study. Am Heart J 1994;128:781 -792.
25. Belardinelli R, Barstow TJ, Nguyen P, Wasserman K. Skeletal muscle oxygenation and oxygen uptake kinetics following constant work rate exercise in chronic congestive heart failure. Am J Cardiol 1997;80:1319-1324.
26. McCully KK, Vandenborne K, DeMeirleir K, Posner JD, Leigh JS, Jr. Muscle metabolism in track athletes, using 31P magnetic resonance spectroscopy. Can J Physiol Pharmacol 1992;70:1353 -1359.
27. Barker AR, Welsman JR, Fulford J, Welford D, Williams CA, Armstrong N. Muscle phosphocreatine and pulmonary oxygen uptake kinetics in children at the onset and offset of moderate intensity exercise. Eur J Appl Physiol 2008;102:727-738.
28. Tanner JM. Growth at adolescence. 2nd edition. Oxford: Black- well Scientific Publications; 1962.
29. Slaughter MH, Lohman TG, Boileau RA, Horswill CA, Stillman RJ, Van Loan MD, Bemben DA. Skinfold equations for estimation of body fatness in children and youth. Hum Biol 1988;60:709-723.
30. Zapletal A, Samanek M, Paul T. Lung function in children and adolescents. Methods, reference values. In: Zapletal A, editor. Progress in respiration research. Vol. 22. Basel, Switzerland: Karger Publishers; 1987. pp. 114-116.
31. Guidelines for the measurement of respiratory function. Recommendations of the British thoracic society and the association of respiratory technicians and physiologists. Respir Med 1994;88:165-194.
32. Nanas S, Nanas J, Kassiotis C, Nikolaou C, Tsagalou E, Sakellariou D, Terovitis I, Papazachou O, Drakos S, Papamicha- lopoulos A, Roussos C. Early recovery of oxygen kinetics after submaximal exercise test predicts functional capacity in patients with chronic heart failure. Eur J Heart Fail 2001;3:685-692.
33. Tanabe Y, Takahashi M, Hosaka Y, Ito M, Ito E, Suzuki K. Prolonged recovery of cardiac output after maximal exercise in patients with chronic heart failure. J Am Coll Cardiol 2000;35:1228-1236.
34. Cohen-Solal A, Laperche T, Morvan D, Geneves M, Caviezel B, Gourgon R. Prolonged kinetics of recovery of oxygen consumption after maximal graded exercise in patients with chronic heart failure. Analysis with gas exchange measurements and NMR spectroscopy. Circulation 1995;91:2924-2932.
35. Shwachman H, Kulczycki LL. Long-term study of one hundred five patients with cystic fibrosis; studies made over a five- to fourteen-year period. AMA J Dis Child 1958;96:6-15.
36. Gaesser GA, Brooks GA. Metabolic bases of excess post-exercise oxygen consumption: a review. Med Sci Sports Exerc 1984;16:29-43.
37. Godfrey S, Mearns M. Pulmonary function and response to exercise in cystic fibrosis. Arch Dis Child 1971;46:144-151.
38. Hirsch JA, Zhang SP, Rudnick MP, Cerny FJ, Cropp GJ. Resting oxygen consumption and ventilation in cystic fibrosis. Pediatr Pulmonol 1989;6:19 - 26.
39. Coates AL, Canny G, Zinman R, Grisdale R, Desmond K, Roumeliotis D, Levison H. The effects of chronic airflow limitation, increased dead space, and the pattern of ventilation on gas exchange during maximal exercise in advanced cystic fibrosis. Am Rev Respir Dis 1988;138:1524-1531.
40. Gallagher CG, Younes M. Breathing pattern during and after maximal exercise in patients with chronic obstructive lung disease, interstitial lung disease, and cardiac disease, and in normal subjects. Am Rev Respir Dis 1986;133:581 -586.
41. Chonan T, elHefnawy AM, Simonetti OP, Cherniack NS. Rate of elimination of excess CO2 in humans. Respir Physiol 1988;73: 379-394.
42. Robinson P, Van Asperen P, Cooper P, McKay K, Fitzgerald D, Selvadurai H. Assessing response to intravenous therapy for pulmonary exacerbations in children with cystic fibrosis. Respirology 2007;12:A22.
43. Yu CC, Li AM, So RC, McManus A, Ng PC, Chu W, Chan D, Cheng F, Chiu WK, Leung CW, Yau YS, Mo KW, Wong EM, Cheung AY, Leung TF, Sung RY, Fok TF. Longer term follow up of aerobic capacity in children affected by severe acute respiratory syndrome (SARS). Thorax 2006;61:240-246.
44. Pouliou E, Nanas S, Papamichalopoulos A, Kyprianou T, Perpati G, Mavrou I, Roussos C. Prolonged oxygen kinetics during early recovery from maximal exercise in adult patients with cystic fibrosis. Chest 2001;119:1073 -1078.
45. Kusenbach G, Wieching R, Barker M, Hoffmann U, Essfeld D. Effects of hyperoxia on oxygen uptake kinetics in cystic fibrosis patients as determined by pseudo-random binary sequence exercise. Eur J Appl Physiol Occup Physiol 1999;79:192-196.
46. de Meer K, Jeneson JA, Gulmans VA, van der Laag J, Berger R. Efficiency of oxidative work performance of skeletal muscle in patients with cystic fibrosis. Thorax 1995;50:980-983.
47. Moser C, Tirakitsoontorn P, Nussbaum E, Newcomb R, Cooper DM. Muscle size and cardiorespiratory response to exercise in cystic fibrosis. Am J Respir Crit Care Med 2000;162:1823-1827.
48. Selvadurai HC, Allen J, Sachinwalla T, Macauley J, Blimkie CJ, Van Asperen PP. Muscle function and resting energy expenditure in female athletes with cystic fibrosis. Am J Respir Crit Care Med 2003;168:1476-1480.
49. Maltais F, Simard AA, Simard C, Jobin J, Desgagnes P, LeBlanc P. Oxidative capacity of the skeletal muscle and lactic acid kinetics during exercise in normal subjects and in patients with COPD. Am J Respir Crit Care Med 1996;153:288-293.
50. Maltais F, Jobin J, Sullivan MJ, Bernard S, Whittom F, Killian KJ, Desmeules M, Belanger M, LeBlanc P. Metabolic and hemodynamic responses of lower limb during exercise in patients with COPD. J Appl Physiol 1998;84:1573-1580.
51. Pianosi PT, Fisk M. Cardiopulmonary exercise performance in prematurely born children. Pediatr Res 2000;47:653-658.
52. Dodd JD, Barry SC, Barry RB, Gallagher CG, Skehan SJ, Masterson JB. Thin-section CT in patients with cystic fibrosis: correlation with peak exercise capacity and body mass index. Radiology 2006;240:236-245.
53. de Jong PA, Nakano Y, Lequin MH, Mayo JR, Woods R, Pare PD, Tiddens HA. Progressive damage on high resolution computed tomography despite stable lung function in cystic fibrosis. Eur Respir J 2004;23:93 -97.
54. Selvadurai HC, McKay KO, Blimkie CJ, Cooper PJ, Mellis CM, Van Asperen PP. The relationship between genotype and exercise tolerance in children with cystic fibrosis. Am J Respir Crit Care Med 2002;165:762-765.
55. Huang NN, Schidlow DV, Szatrowski TH, Palmer J, Laraya-Cuasay LR, Yeung W, Hardy K, Quitell L, Fiel S. Clinical features, survival rate, and prognostic factors in young adults with cystic fibrosis. Am J Med 1987;82:871 -879.
56. Sharples L, Hathaway T, Dennis C, Caine N, Higenbottam T, Wallwork J. Prognosis of patients with cystic fibrosis awaiting heart and lung transplantation. J Heart Lung Transplant 1993;12:669-674.
57. Javadpour SM, Selvadurai H, Wilkes DL, Schneiderman-Walker J, Coates AL. Does carbon dioxide retention during exercise predict a more rapid decline in FEV1 in cystic fibrosis? Arch Dis Child 2005;90:792-795.
58. Lebecque P, Lapierre JG, Lamarre A, Coates AL. Diffusion capacity and oxygen desaturation effects on exercise in patients with cystic fibrosis. Chest 1987;91:693-697.
59. Cerny FJ, Pullano TP, Cropp GJ. Cardiorespiratory adaptations to exercise in cystic fibrosis. Am Rev Respir Dis 1982;126:217-220.
60. Cropp GJ, Pullano TP, Cerny FJ, Nathanson IT. Exercise tolerance and cardiorespiratory adjustments at peak work capacity in cystic fibrosis. Am Rev Respir Dis 1982;126:211 - 216.
61. Marcotte JE, Canny GJ, Grisdale R, Desmond K, Corey M, Zinman R, Levison H, Coates AL. Effects of nutritional status on exercise performance in advanced cystic fibrosis. Chest 1986;90: 375-379.
62. Marcotte JE, Grisdale RK, Levison H, Coates AL, Canny GJ. Multiple factors limit exercise capacity in cystic fibrosis. Pediatr Pulmonol 1986;2:274-281.
63. Lands LC, Heigenhauser GJ, Jones NL. Analysis of factors limiting maximal exercise performance in cystic fibrosis. Clin Sci (Lond) 1992;83:391 -397.
64. Dodd JD, Barry SC, Gallagher CG. Respiratory factors do not limit maximal symptom-limited exercise in patients with mild cystic fibrosis lung disease. Respir Physiol Neurobiol 2006;152: 176-185.
65. Moorcroft AJ, Dodd ME, Morris J, Webb AK. Symptoms, lactate and exercise limitation at peak cycle ergometry in adults with cystic fibrosis. Eur Respir J 2005;25:1050-1056.
66. Moorcroft AJ, Dodd ME, Webb AK. Exercise testing and prognosis in adult cystic fibrosis. Thorax 1997;52:291 -293.
67. Pianosi P, LeBlanc J, Almudevar A. Relationship between FEV1 and peak oxygen uptake in children with cystic fibrosis. Pediatr Pulmonol 2005;40:324-329.