Oxidative capacity of the skeletal muscle and lactic acid kinetics during exercise in normal subjects and in patients with COPD

American Journal of Respiratory and Critical Care Medicine

Volumn 153, Issue 1, 1996, Pages 288-293

  Maltais, François ^a   Simard, Andrée Anne ^b   Simard, Clermont ^b   Jobin, Jean ^b   Desgagnés, Pierre ^b   LeBlanc, Pierre ^b   Janvier, Richard ^b  

^a LAVAL UNIVERSITY   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AEROBIC METABOLISM; AGED; AIRWAY OBSTRUCTION; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; ENZYME ACTIVITY; EXERCISE TOLERANCE; FEMALE; FORCED EXPIRATORY VOLUME; GLYCOLYSIS; HUMAN; KINETICS; LACTIC ACIDOSIS; MALE; MUSCLE FUNCTION; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SKELETAL MUSCLE;

EID: 0030042996     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.153.1.8542131     Document Type: Article

References (41)

1. Gallagher, C. G. 1991. Exercise and chronic obstructive pulmonary disease. Med. Clin. North Am. 74:619-641.
2. Jones, N. L., and K. J. Killian. 1991. Limitation of exercise in chronic airway obstruction. In N. S. Cherniack, editor. Chronic Obstructive Pulmonary Disease. W. B. Saunders, Philadelphia. 196-206.
3. Killian, K. J., P. Leblanc, D. H. Martin, E. Summers, N. L. Jones, and E. J. M. Campbell. 1992. Exercise capacity and ventilatory, circulatory, and symptom limitation in patients with airflow limitation. Am. Rev. Respir. Dis. 146:935-940.
4. Allard, C., N. L. Jones, and K. J. Killian. 1989. Static peripheral skeletal muscle strength and exercise capacity in patients with chronic airflow obstruction (abstract). Am. Rev. Respir. Dis. 139:A90.
5. 31P-NMR study of skeletal muscle metabolism in patients with chronic respiratory impairment. Am. Rev. Respir. Dis. 146:1019-1024.
6. Payen, J. F., B. Wuyam, P. Levy, H. Reutenauer, P. Stieglitz, B. Paramelle, and J. F. Le Bas. 1993. Muscular metabolism during oxygen supplementation in patients with chronic hypoxia. Am. Rev. Respir. Dis. 147:592-598.
7. Wuyam, B., J. F. Payen, P. Levy, H. Bensaidane, H. Reutenauer, J. F. Le Bas, and A. L. Benabid. 1992. Metabolism and aerobic capacity of skeletal muscle in chronic respiratory failure related to chronic obstructive pulmonary disease. Eur. Respir. J. 5:157-162.
8. Fiaccadori, E., S. Del Canale, P. Vitali, E. Coffrini, N. Ronda, and A. Guariglia. 1987. Skeletal muscle energetics, acid-base equilibrium and lactate metabolism in patients with severe hypercapnia and hypoxia. Chest 92:883-887.
9. Gertz, I., G. Hedenstierna, G. Hellers, and J. Wahren. 1977. Muscle metabolism in patients with chronic obstructive lung disease and acute respiratory failure. Clin. Sci. Mol. Med. 52:395-403.
10. Jakobsson, P., L. Jorfeldt, and J. Henriksson. 1995. Metabolic enzyme activity in the quadriceps femoris muscle in patients with severe chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 151: 374-377.
11. Casaburi, R., A. Patessio, F. Ioli, S. Zanaboni, C. F. Donner, and K. Wasserman. 1991. Reductions in exercise lactic acidosis and ventilation as a result of exercise training in patients with obstructive lung disease. Am. Rev. Respir. Dis. 143:9-18.
12. Simard, A. A., P. Leblanc, J. Jobin, P. Desgagnés, M. J. Breton, and F. Maltais. 1994. Lactic acid kinetics during exercise in young and older normal subjects and in COPD patients. Eur. Respir. J. 7:96s.
13. Knudson, R. J., R. C. Slatin, M. D. Lebowitz, and B. Burrows. 1976. The maximal expiratory flow-volume curve: normal standards, variability and effects of age. Am. Rev. Respir. Dis. 113:587-600.
14. Goldman, H. I., and M. R. Becklake. 1959. Respiratory function tests: normal values at medium altitudes and the prediction of normal results. Am. Rev. Tuberc. 79:454-467.
15. Cotes, J. E., and A. M. Hall. 1970. The transfer factors for the lung; normal values in adults. In P. Arcangeli, editor. Normal Values for Respiratory Function in Man. Panminerva Medica, Torino. 327-343.
16. Bergström, J. 1962. Muscle electrolytes in man. Determination by neutron activation analysis on needle biopsy specimens. A study on normal subjects, kidney patients and patients with chronic diarrhoea. Scand. J. Clin. Lab. Invest. 14:1-110.
17. Bergström, J., L. Hermansen, E. Hultman, and B. Saltin. 1967. Diet, muscle glycogen and physical performance. Acta Physiol. Scand. 71: 140-150.
18. Opie, L. H., and E. A. Newsholme. 1967. The activities of fructose 1,6-diphosphatase, phosphofructokinase and phosphoenolpyruvate carboxykinase in white muscle and red muscle. Biochem. J. 103: 391-399.
19. Zammit, V. A., and E. A. Newsholme. 1976. The maximum activities of hexokinase, phosphorylase, phosphofructokinase, glycerol phosphate dehydrogenase, lactate dehydrogenase, octopine dehydrogenase, phosphoenolpyruvate carboxykinase, nucleoside diphosphatekinase, glutamate-oxalate transaminase and arginine kinase in relation of carbohydrate utilisation in muscle from invertebrates. Biochem. J. 160: 447-462.
20. Srere, P. A. 1969. Citrate synthase. Methods Enzymol. 13:3-11.
21. Wasserman, K., and A. Koike. 1992. Is the anaerobic threshold truly anaerobic? Chest 101:211s-218s.
22. Hughson, R. L., K. H. Weisiger, and G. D. Swanson. 1987. Blood lactate concentration increases as a continuous function in progressive exercise. J. Appl. Physiol. 62:1975-1981.
23. Beaver, W. L., K. Wasserman, and B. J. Whipp. 1985. Improved detection of lactate threshold during exercise using a log-log transformation. J. Appl. Physiol. 59:1936-1940.
24. Heymsfield, S. B., C. McManus, J. Smith, V. Stevens, and D. W. Nixon. 1982. Anthropometric measurements of muscle mass: revised equations for calculating bone-free muscle area. Am. J. Clin. Nutr. 36: 680-690.
25. Neter, J., W. Waserman, and M. H. Kutner. 1985. Other uses of independent indication variables. In R. D. Irwin, editor. Applied Linear Statistical Models. Irvin Inc., Homewood, IL. 346-348.
26. Jones, N. L. 1988. Clinical Exercise Testing, 3rd ed. W. B. Sanders, Philadelphia.
27. Green, H. J., J. R. Sutton, A. Cymerman, P. M. Young, and C. S. Houston. 1989. Operation Everest II: adaptations in human skeletal muscle. J. Appl. Physiol. 66:2454-2461.
28. 31P-nuclear magnetic resonance evidence of abnormal skeletal muscle metabolism in patients with chronic lung disease and congestive heart failure. Eur. Respir. J. 5:163-169.
29. Newsholme, E. A. 1980. Use of enzyme activity measurements in studies on the biochemistry of exercise. Int. J. Sports Med. 1:100-102.
30. Jones, N. L., and R. H. T. Edwards. 1971. Exercise tolerance in chronic airway obstruction. Am. Rev. Respir. Dis. 103:477-491.
31. Belman, M. J. 1986. Exercise in chronic obstructive pulmonary disease. Clin. Chest Med. 7:585-597.
32. Karlsson, J., B. Diamant, and K. Folkers. 1992. Exercise-limiting factors in respiratory distress. Respiration 59:18-23.
33. Beaver, W. L., K. Wasserman, and B. J. Whipp. 1986. Bicarbonate buffering of lactic acid generated during exercise. J. Appl. Physiol. 60:472-486.
34. Saltin, B., and P. D. Gollnick. 1982. Skeletal muscle adaptability: significance for metabolism and performance. The Handbook of Physiology: The Skeletal Muscle System. American Physiological Society, Bethesda, MD. 555-631.
35. Sullivan, M. J., H. J. Green, and F. R. Cobb. 1991. Altered skeletal muscle metabolic response to exercise in chronic heart failure: relation to skeletal muscle aerobic enzyme activity. Circulation 84:1597-1607.
36. Ivy, J. L., R. T. Withers, P. J. Van Handel, D. H. Elger, and D. L. Costill. 1980. Muscle respiratory capacity and fiber type as determinants of the lactate threshold. J. Appl. Physiol. 48:523-547.
37. Holloszy, J. O. 1967. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. J. Biol. Chem. 242:2278-2282.
38. Rogers, M. A., and W. J. Evans. 1993. Changes in skeletal muscle with aging: effects of exercise training. In J. O. Holloszy, editor. Exercise and Sports Sciences Reviews, 21st ed. Williams and Wilkins, Philadelphia. 65-102.
39. Booth, F. W., and P. D. Gollnick. 1983. Effects of disuse on the structure and function of skeletal muscle. Med. Sci. Sports Exerc. 15:415-420.
40. Howald, H., D. Pette, J. A. Simoneau, A. Uber, H. Hoppeler, and P. Cerretelli. 1990. Effects of chronic hypoxia on muscle enzyme activities. Int. J. Sports Med. 11:s10-s14.
41. Graham, T., B. A. Wilson, M. Sample, J. van Dijk, and A. Bonen. 1980. The effects of hypercapnia on metabolic responses to progressive exhaustive work. Med. Sci. Sports Exerc. 12:278-284.