Enhancement of calcium transport in Caco-2 monolayer through PKC ζ-dependent Cav1.3-mediated transcellular and rectifying paracellular pathways by prolactin

American Journal of Physiology - Cell Physiology

Volumn 296, Issue 6, 2009, Pages

  Thongon, Narongrit ^a,b   Nakkrasae, La Iad ^a   Thongbunchoo, Jirawan ^a   Krishnamra, Nateetip ^a   Charoenphandhu, Narattaphol ^a  

^a Mahidol University   (Thailand)

^b BURAPHA UNIVERSITY   (Thailand)

Author keywords

Calcium uptake; Protein kinase C; Rectification; Small interfering RNA; Voltage dependent calcium transport

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CALBINDIN; CALCIUM; CALCIUM CHANNEL; NIFEDIPINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROLACTIN; PROTEIN CAV1.3; PROTEIN KINASE C ZETA; TRIFLUOPERAZINE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 6; VERAPAMIL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE; CONTROLLED STUDY; GENETIC TRANSCRIPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; VOLTAGE CLAMP;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CACO-2 CELLS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; ENZYME INHIBITORS; HUMANS; INTESTINAL MUCOSA; MEMBRANE POTENTIALS; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; PROLACTIN; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SODIUM-CALCIUM EXCHANGER; TIME FACTORS; TRPV CATION CHANNELS;

EID: 66749092111     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00053.2009     Document Type: Article

References (52)

1. 2+ absorption in small intestine. Arch Biochem Biophys 460: 227-232, 2007.
2. Benn BS, Ajibade D, Porta A, Dhawan P, Hediger M, Peng JB, Jiang Y, Oh GT, Jeung EB, Lieben L, Bouillon R, Carmeliet G, Christakos S. Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k. Endocrinology 149: 3196-3205, 2008.
3. 9k and parvalbumin are exclusively located along basolateral membranes in rat distal nephron. J Am Soc Nephrol 2: 1122-1129, 1991.
4. Boass A, Lovdal JA, Toverud SU. Pregnancy- and lactation-induced changes in active intestinal calcium transport in rats. Am J Physiol Gastrointest Liver Physiol 263: G127-G134, 1992.
5. Charoenphandhu N, Krishnamra N. Prolactin is an important regulator of intestinal calcium transport. Can J Physiol Pharmacol 85: 569-581, 2007. (Pubitemid 47518025)
6. 2+-ATPase activities in the duodenum of female rats. Can J Physiol Pharmacol 84: 555-563, 2006.
7. Charoenphandhu N, Tudpor K, Pulsook N, Krishnamra N. Chronic metabolic acidosis stimulated transcellular and solvent drag-induced calcium transport in the duodenum of female rats. Am J Physiol Gastrointest Liver Physiol 291: G446-G455, 2006. (Pubitemid 44330165)
8. Charoenphandhu N, Wongdee K, Teerapornpuntakit J, Thongchote K, Krishnamra N. Transcriptome responses of duodenal epithelial cells to prolactin in pituitary-grafted rats. Mol Cell Endocrinol 296: 41-52, 2008.
9. Couchourel D, Leclerc M, Filep J, Brunette MG. Testosterone enhances calcium reabsorption by the kidney. Mol Cell Endocrinol 222: 71-81, 2004. (Pubitemid 38900816)
10. 3-mediated rapid stimulation of intestinal calcium transport (transcaltachia). Endocrinology 127: 39-45, 1990.
11. 2+ transport). Endocrinology 127: 2475-2480, 1990.
12. Eisenman G, Horn R. Ionic selectivity revisited: the role of kinetic and equilibrium processes in ion permeation through channels. J Membr Biol 76: 197-225, 1983. (Pubitemid 14201481)
13. 9K and calmodulin: possible importance in intestinal calcium absorption. Cell Calcium 10: 189-203, 1989.
14. Ferrante PL, Freeman DE, Whitlock RH, Kronfeld DS. Effect of D-glucose on in vitro short-circuit current in neonatal calf jejunum and rabbit ileum. Am J Vet Res 49: 715-719, 1988.
15. 2+ absorption between enterocytes. Mol Biol Cell 19: 1912-1921, 2008.
16. 1 receptor to the nucleus. Br J Pharmacol 139: 721-732, 2003.
17. Hirsch E, Costa C, Ciraolo E. Phosphoinositide 3-kinases as a common platform for multi-hormone signaling. J Endocrinol 194: 243-256, 2007. (Pubitemid 47249663)
18. Hoenderop JG, Nilius B, Bindels RJ. Calcium absorption across epithelia. Physiol Rev 85: 373-422, 2005. (Pubitemid 40171261)
19. 2+ channel TRPV6. Am J Physiol Gastrointest Liver Physiol 292: G92-G97, 2007.
20. Jantarajit W, Thongon N, Pandaranandaka J, Teerapornpuntakit J, Krishnamra N, Charoenphandhu N. Prolactin-stimulated transepithelial calcium transport in duodenum and Caco-2 monolayer are mediated by the phosphoinositide 3-kinase pathway. Am J Physiol Endocrinol Metab 293: E372-E384, 2007.
21. Kapus A, Szászi K. Coupling between apical and paracellular transport processes. Biochem Cell Biol 84: 870-880, 2006. (Pubitemid 46450687)
22. Karbach U, Feldmeier H. The cecum is the site with the highest calcium absorption in rat intestine. Dig Dis Sci 38: 1815-1824, 1993. (Pubitemid 23311932)
23. Khanal RC, Nemere I. Endocrine regulation of calcium transport in epithelia. Clin Exp Pharmacol Physiol 35: 1277-1287, 2008.
24. Khanal RC, Nemere I. Regulation of intestinal calcium transport. Annu Rev Nutr 28: 179-196, 2008.
25. Krishnamra N, Taweerathitam P. Acute effect of prolactin on active calcium absorption in rats. Can J Physiol Pharmacol 73: 1185-1189, 1995.
26. Krishnamra N, Wirunrattanakij Y, Limlomwongse L. Acute effects of prolactin on passive calcium absorption in the small intestine by in vivo perfusion technique. Can J Physiol Pharmacol 76: 161-168, 1998. (Pubitemid 28307788)
27. 9k gene knockout is compensated for by the induction of other calcium transporter genes in a mouse model. J Bone Miner Res 22: 1968-1978, 2007.
28. Lee SH, Kunz J, Lin SH, Yu-Lee LY. 16-kDa prolactin inhibits endothelial cell migration by down-regulating the Ras-Tiam1-Rac1-Pak1 signaling pathway. Cancer Res 67: 11045-11053, 2007. (Pubitemid 350145935)
29. Little D, Dean RA, Young KM, McKane SA, Martin LD, Jones SL, Blikslager AT. PI3K signaling is required for prostaglandin-induced mucosal recovery in ischemia-injured porcine ileum. Am J Physiol Gastrointest Liver Physiol 284: G46-G56, 2003. (Pubitemid 36076249)
30. + channels. Annu Rev Physiol 66: 103-129, 2004.
31. v1.3 induces terminal web myosin II phosphorylation and apical GLUT2 insertion in rat intestine. J Physiol 580: 605-616, 2007.
32. McLaughlin J, Padfield PJ, Burt JP, O'Neill CA. Ochratoxin A increases permeability through tight junctions by removal of specific claudin isoforms. Am J Physiol Cell Physiol 287: C1412-C1417, 2004. (Pubitemid 39382902)
33. Mellor H, Parker PJ. The extended protein kinase C superfamily. Biochem J 332: 281-292, 1998. (Pubitemid 28271856)
34. Morgan EL, Mace OJ, Affleck J, Kellett GL. Apical GLUT2 and Cav1.3: regulation of rat intestinal glucose and calcium absorption. J Physiol 580: 593-604, 2007. (Pubitemid 46564184)
35. Morgan EL, Mace OJ, Helliwell PA, Affleck J, Kellett GL. A role for Cav1.3 in rat intestinal calcium absorption. Biochem Biophys Res Commun 312: 487-493, 2003. (Pubitemid 37445198)
36. Motulsky H, Christopoulos A. Fitting Models to Biological Data Using Linear and Nonlinear Regression: A Practical Guide to Curve Fitting. New York, NY: Oxford Univ. Press, 2004, p. 312-321.
37. Murphy EF, Hooiveld GJ, Muller M, Calogero RA, Cashman KD. Conjugated linoleic acid alters global gene expression in human intestinal-like Caco-2 cells in an isomer-specific manner. J Nutr 137: 2359-2365, 2007. (Pubitemid 350058701)
38. Nakane M, Ma J, Rose AE, Osinski MA, Wu-Wong JR. Differential effects of vitamin D analogs on calcium transport. J Steroid Biochem Mol Biol 103: 84-89, 2007. (Pubitemid 44821814)
39. Powell DJ, Hajduch E, Kular G, Hundal HS. Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCζ-dependent mechanism. Mol Cell Biol 23: 7794-7808, 2003. (Pubitemid 37271476)
40. Rexhepaj R, Artunc F, Metzger M, Skutella T, Lang F. PI3-kinase-dependent electrogenic intestinal transport of glucose and amino acids. Pflügers Arch 453: 863-870, 2007. (Pubitemid 46294924)
41. Sabah NH. Rectification in biological membranes. IEEE Eng Med Biol Mag 19: 106-113, 2000. (Pubitemid 30056693)
42. Samarin SN, Ivanov AI, Flatau G, Parkos CA, Nusrat A. Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions. Mol Biol Cell 18: 3429-3439, 2007. (Pubitemid 47378682)
43. Tang VW, Goodenough DA. Paracellular ion channel at the tight junction. Biophys J 84: 1660-1673, 2003. (Pubitemid 36322930)
44. Tanrattana C, Charoenphandhu N, Limlomwongse L, Krishnamra N. Prolactin directly stimulated the solvent drag-induced calcium transport in the duodenum of female rats. Biochim Biophys Acta 1665: 81-91, 2004. (Pubitemid 39303573)
45. Thongon N, Nakkrasae LI, Thongbunchoo J, Krishnamra N, Charoenphandhu N. Prolactin stimulates transepithelial calcium transport and modulates paracellular permselectivity in Caco-2 monolayer: mediation by PKC and ROCK pathways. Am J Physiol Cell Physiol 294: C1158-C1168, 2008.
46. 2+ channels in small intestine as studied by quantitative mRNA detection. Am J Physiol Gastrointest Liver Physiol 285: G78-G85, 2003.
47. Van Itallie CM, Anderson JM. Claudins and epithelial paracellular transport. Annu Rev Physiol 68: 403-429, 2006.
48. Wall MJ, Declusin RJ, Soergel KH, Baker RD. The effect of short chain fatty acids on transmural electrical potential across rat small intestine in vivo. Biochim Biophys Acta 433: 654-661, 1976.
49. Wasserman RH, Chandler JS, Meyer SA, Smith CA, Brindak ME, Fullmer CS, Penniston JT, Kumar R. Intestinal calcium transport and calcium extrusion processes at the basolateral membrane. J Nutr 122: 662-671, 1992.
50. Yee S. In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man - fact or myth. Pharm Res 14: 763-766, 1997. (Pubitemid 27281671)
51. 2+ transport). Biochem Biophys Res Commun 186: 69-73, 1992.
52. Zweibaum A, Triadou N, Kedinger M, Augeron C, Robine-Leon S, Pinto M, Rousset M, Haffen K. Sucrase-isomaltase: a marker of foetal and malignant epithelial cells of the human colon. Int J Cancer 32: 407-412, 1983.