Transfer Region of pO113 from Enterohemorrhagic Escherichia coli: Similarity with R64 and Identification of a Novel Plasmid-Encoded Autotransporter, EpeA

Infection and Immunity

Volumn 71, Issue 11, 2003, Pages 6307-6319

  Leyton, Denisse L ^a   Sloan, Joan ^a   Hill, Rebecca E ^a   Doughty, Steven ^a   Hartland, Elizabeth L ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CARRIER PROTEIN; HEMOLYSIN; HYALURONIDASE; NUCLEOTIDE; PROTEIN EPEA; PROTEIN ESPP; PROTEIN RSF1010; PROTEIN SPATE; SERINE PROTEINASE; SHIGA TOXIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; DIARRHEA; ENTEROHEMORRHAGIC ESCHERICHIA COLI; ENZYME ACTIVITY; EPITHELIUM CELL; ESCHERICHIA COLI; HEMOLYTIC UREMIC SYNDROME; INTESTINE CELL; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PLASMID; PLASMID PO113; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY;

ESCHERICHIA COLI O157; ESCHERICHIA COLI PROTEINS; HEMOLYSIN PROTEINS; HYDROGEN-ION CONCENTRATION; PLASMIDS; POLYSACCHARIDE-LYASES; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; TEMPERATURE;

EID: 0242286559     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.11.6307-6319.2003     Document Type: Article

References (41)

1. Benjelloun-Touimi, Z., P. J. Sansonetti, and C. Parsot. 1995. SepA, the major extracellular protein of Shigella flexneri: autonomous secretion and involvement in tissue invasion. Mol. Microbiol. 17:123-135.
2. Boerlin, P., S. Chen, J. K. Colbourne, R. Johnson, S. De Grandis, and C. Gyles. 1998. Evolution of enterohemorrhagic Escherichia coli hemolysin plasmids and the locus for enterocyte effacement in Shiga toxin-producing E. coli. Infect. Immun. 66:2553-2561.
3. Brunder, W., H. Schmidt, M. Frosch, and H. Karch. 1999. The large plasmids of Shiga-toxin-producing Escherichia coli (STEC) are highly variable genetic elements. Microbiology 145:1005-1014.
4. Brunder, W., H. Schmidt, and H. Karch. 1997. EspP, a novel extracellular serine protease of enterohaemorrhagic Escherichia coli O157:H7 cleaves human coagulation factor V. Mol. Microbiol. 24:767-778.
5. Burland, V., Y. Shao, N. T. Perna, G. Plunkett, H. J. Sofia, and F. R. Blattner. 1998. The complete DNA sequence and analysis of the large virulence plasmid of Escherichia coli O157:H7. Nucleic Acids Res. 26:4196-4204.
6. Datsenko, K. A., and B. L. Wanner. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. USA 97:6640-6645.
7. Davis, J., A. L. Smith, W. R. Hughes, and M. Golomb. 2001. Evolution of an autotransporter: domain shuffling and lateral transfer from pathogenic Haemophilus to Neisseria. J. Bacteriol. 183:4626-4635.
8. Dempsey, W. B. 1994. Regulation of R100 conjugation requires traM in cis to tral. Mol. Microbiol. 13:987-1000.
9. Djafari, S., F. Ebel, C. Deibel, S. Kramer, M. Hudel, and T. Chakraborty. 1997. Characterization of an exported protease from Shiga toxin-producing Escherichia coli. Mol. Microbiol. 25:771-784.
10. Doughty, S., J. Sloan, V. Bennett-Wood, M. Robertson, R. M. Robins-Browne, and E. L. Hartland. 2002. Identification of a novel fimbrial gene cluster related to long polar fimbriae in locus of enterocyte effacement-negative strains of enterohemorrhagic Escherichia coli. Infect. Immun. 70:6761-4769.
11. Dytoc, M. T., A. Ismaili, D. J. Philpott, R. Soni, J. L. Brunton, and P. M. Sherman. 1994. Distinct binding properties of eaeA-negative verocytotoxin-producing Escherichia coli of serotype O113:H21. Infect. Immun. 62:3494-3505.
12. Elliott, E. J., R. M. Robins-Browne, E. V. O'Loughlin P. Henning, G. G. Hogg, J. Knight, H. Powell, D. Redmond, and V. Bennett-Wood. 2001. Nationwide surveillance of haemolytic uraemic syndrome in Australia: a comparison of endemic cases with those in a single epidemic. Arch. Dis. Child. 85:1-4.
13. Elliott, S. J., L. A. Wainwright, T. K. McDaniel, K. G. Jarvis, Y. K. Deng, L. C. Lai, B. P. McNamara, M. S. Donnenberg, and J. B. Kaper. 1998. The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69. Mol. Microbiol. 28:1-4.
14. Eslava, C., F. Navarro-Garcia, J. R. Czeczulin, I. R. Henderson, A. Cravioto, and J. P. Nataro. 1998. Pet, an autotransporter enterotoxin from enteroaggregative Escherichia coli. Infect. Immun. 66:3155-3163.
15. Furste, J. P., W. Pansegrau, R. Frank, H. Blocker, P. Scholz, M. Bagdasarian, and E. Lanka. 1986. Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector. Gene 48:119-131.
16. Guyer, D. M., I. R. Henderson, J. P. Nataro, and H. L. Mobley. 2000. Identification of Sat, an autotransporter toxin produced by uropathogenic Escherichia coli. Mol. Microbiol. 38:53-66.
17. Gyohda, A., N. Furuya, N. Kogure, and T. Komano. 2002. Sequence-specific and non-specific binding of the Rci protein to the asymmetric recombination sites of the R64 shufflon. J. Mol. Biol. 318:975-983.
18. Henderson, I. R., J. Czeczulin, C. Eslava, F. Noriega, and J. P. Nataro. 1999. Characterization of Pic, a secreted protease of Shigella flexneri and entero-aggregative Escherichia coli. Infect. Immun. 67:5587-5596.
19. Henderson, I. R., F. Navarro-Garcia, and J. P. Nataro. 1998. The great escape: structure and function of the autotransporter proteins. Trends Microbiol. 6:370-378.
20. Hendrixson, D. R., M. L. de la Morena, C. Stathopoulos, and J. W. St. Geme III. 1997. Structural determinants of processing and secretion of the Haemophilus influenzae Hap protein. Mol. Microbiol 26:505-518.
21. Hendrixson, D. R., and J. W. St. Geme III. 1998. The Haemophilus influenzae Hap serine protease promotes adherence and microcolony formation, potentiated by a soluble host protein. Mol. Cell 2:841-850.
22. Ishiwa, A., and T. Komano. 2000. The lipopolysaccharide of recipient cells is a specific receptor for PilV proteins, selected by shufflon DNA rearrangement, in liquid matings with donors bearing the R64 plasmid. Mol. Gen. Genet. 263:159-164.
23. Karmali, M. A., M. Petric, C. Lim, P. C. Fleming, G. S. Arbus, and H. Lior. 1985. The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli. J. Infect. Dis. 151:775-782.
24. Kim, S. R., N. Funayama, and T. Komano. 1993. Nucleotide sequence and characterization of the traABCD region of IncI1 plasmid R64. J. Bacteriol. 175:5035-5042.
25. Kim, S. R., and T. Komano. 1997. The plasmid R64 thin pilus identified as a type IV pilus. J. Bacteriol. 179:3594-3603.
26. Komano, T., T. Yoshida, K. Narahara, and N. Furuya. 2000. The transfer region of IncI1 plasmid R64: similarities between R64 tra and Legionella icm/ dot genes. Mol. Microbiol. 35:1348-1359.
27. Loveless, B. J., and M. H. Saier, Jr. 1997. A novel family of channel-forming, autotransporting, bacterial virulence factors. Mol. Membr. Biol. 14:113-123.
28. Moses, E. K., J. I. Rood, W. K. Yong, and G. G. Riffkin. 1989. Molecular analysis of one of multiple protease-encoding genes from the prototype virulent strain of Bacteroides nodosus. Gene 77:219-228.
29. Nataro, J. P., and J. B. Kaper. 1998. Diarrheagenic Escherichia coli. Clin. Microbiol. Rev. 11:142-201.
30. Nicholls, L., T. H. Grant, and R. M. Robins-Browne. 2000. Identification of a novel genetic locus that is required for in vitro adhesion of a clinical isolate of enterohaemorrhagic Escherichia coli to epithelial cells. Mol. Microbiol. 35:275-288.
31. Palombo, E. A., K. Yusoff, V. A. Stanisich, V. Krishnapillai, and N. S. Willetts. 1989. Cloning and genetic analysis of tra cistrons of the Tra 2/Tra 3 region of plasmid RP1. Plasmid 22:59-69.
32. Paton, A. W., P. Srimanote, M. C. Woodrow, and J. C. Paton. 2001. Characterization of Saa, a novel autoagglutinating adhesin produced by locus of enterocyte effacement-negative Shiga-toxigenic Escherichia coli strains that are virulent for humans. Infect. Immun. 69:6999-7009.
33. Paton, A. W., M. C. Woodrow, R. M. Doyle, J. A. Lanser, and J. C. Paton. 1999. Molecular characterization of a Shiga toxigenic Escherichia coli O113: H21 strain lacking eae responsible for a cluster of cases of hemolytic-uremic syndrome. J. Clin. Microbiol. 37:3357-3361.
34. Perna, N. T., G. Plunkett III, V. Burland, B. Mau, J. D. Glasner, D. J. Rose, G. F. Mayhew, P. S. Evans, J. Gregor, H. A. Kirkpatrick, G. Posfai, J. Hackett, S. Klink, A. Boutin, Y. Shao, L. Miller, E. J. Grotbeck, N. W. Davis, A. Lim, E. T. Dimalanta, K. D. Potamousis, J. Apodaca, T. S. Anantharaman, J. Lin, G. Yen, D. C. Schwartz, R. A. Welch, and F. R. Blattner. 2001. Genome sequence of enterohaemorrhagic Escherichia coli O157:H7. Nature 409:529-533.
35. Sambrook, J., E. F. Fritsch, T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Press, Cold Spring Harbor, N.Y.
36. Schmidt, H., and H. Karch. 1996. Enterohemolytic phenotypes and genotypes of Shiga toxin-producing Escherichia coli O111 strains from patients with diarrhea and hemolytic-uremic syndrome. J. Clin. Microbiol. 34:2364-2367.
37. Schmidt, H., W. L. Zhang, U. Hemmrich, S. Jelacic, W. Brunder, P. I. Tarr, U. Dobrindt, J. Hacker, and H. Karch. 2001. Identification and characterization of a novel genomic island integrated at selC in locus of enterocyte effacement-negative Shiga toxin-producing Escherichia coli. Infect. Immun. 69:6863-6873.
38. Srimanote, P., A. W. Paton, and J. C. Paton. 2002. Characterization of a novel type IV pilus locus encoded on the large plasmid of locus of enterocyte effacement-negative Shiga-toxigenic Escherichia coli strains that are virulent for humans. Infect. Immun. 70:3094-3100.
39. Stathopoulos, C., D. L. Provence, and R. Curtiss III. 1999. Characterization of the avian pathogenic Escherichia coli hemagglutinin Tsh, a member of the immunoglobulin A protease-type family of autotransporters. Infect. Immun. 67:772-781.
40. Van den Bosch, L., P. A. Manning, and R. Morona. 1997. Regulation of O-antigen chain length is required for Shigella flexneri virulence. Mol. Microbiol. 23:765-775.
41. Young, A. R., N. Mancuso, E. N. Meeusen, and V. M. Bowles. 2000. Characterization of proteases involved in egg hatching of the sheep blowfly, Lucilia cuprina. Int. J. Parasitol. 30:925-932.