Hydrogen sulfide destroys lipid hydroperoxides in oxidized LDL

Biochemical Journal

Volumn 420, Issue 2, 2009, Pages 277-281

  Muellner, Markus K ^a   Schreier, Sabine M ^a   Laggner, Hilde ^a   Hermann, Marcela ^b   Esterbauer, Harald ^a   Exner, Markus ^c   Gmeiner, Bernhard M K ^a   Kapiotis, Stylianos ^a,d  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c Labor Gruppenpraxis Bauer Spitzauer and Partner   (Austria)

^d Hospital of the Divine Redeemer   (Austria)

Author keywords

(9S) hydroperoxy (10E,12Z) octadecadienoic acid (9 HPODE); (9S) hydroxy (10E,12Z) octadecadienoic acid (9 HODE); Atherosclerosis; Hydrogen sulfide (H2S); Lipid hydroperoxide; Low density lipoprotein (LDL) oxidation

Indexed keywords

(9S)-HYDROPEROXY-(10E,12Z)-OCTADECADIENOIC ACID (9-HPODE); (9S)-HYDROXY-(10E,12Z)-OCTADECADIENOIC ACID (9-HODE); ATHEROSCLEROSIS; HPLC ANALYSIS; LIPID HYDROPEROXIDES; LOW DENSITY LIPOPROTEINS; LOW-DENSITY-LIPOPROTEIN (LDL) OXIDATION; OXYGENASE; PRE-TREATMENT; VASCULATURE;

ENDOTHELIAL CELLS; HYDROGEN; HYDROGEN SULFIDE; OXIDATION; SULFUR DETERMINATION;

ACIDS;

9 HYDROPEROXY 10,12 OCTADECADIENOIC ACID; DIMORPHECOLIC ACID; FATTY ACID DERIVATIVE; HEME OXYGENASE 1; HYDROGEN SULFIDE; LIPID HYDROPEROXIDASE; LIPID PEROXIDASE; OXIDIZED LOW DENSITY LIPOPROTEIN; UNCLASSIFIED DRUG; 9 HYDROPEROXY 11,12 OCTADECADIENOIC ACID; 9-HYDROPEROXY-11,12-OCTADECADIENOIC ACID; 9-HYDROXY-10,12-OCTADECADIENOIC ACID; CONJUGATED LINOLEIC ACID; LINOLEIC ACID; LIPID PEROXIDE; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANTIATHEROGENIC ACTIVITY; ARTICLE; ATHEROGENESIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG PROTEIN BINDING; ENDOTHELIUM CELL; FATTY ACID ANALYSIS; FATTY ACID METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIPID COMPOSITION; PRIORITY JOURNAL; ANALYSIS OF VARIANCE; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME;

ANALYSIS OF VARIANCE; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME OXYGENASE-1; HUMANS; HYDROGEN SULFIDE; LINOLEIC ACIDS; LINOLEIC ACIDS, CONJUGATED; LIPID PEROXIDES; LIPOPROTEINS, LDL; MALONDIALDEHYDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TIME FACTORS;

EID: 66549088800     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20082421     Document Type: Article

References (37)

1. Steinberg, D. (1997) Lewis A. Conner Memorial Lecture: oxidative modification of LDL and atherogenesis. Circulation 95, 1062-1071
2. Steinberg, D., Parthasarathy, S., Carew, T., Khoo, J. and Witztum, J. (1989) Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320, 915-924
3. Berliner, J. A. and Heinecke, J. W. (1996) The role of oxidized lipoproteins in atherogenesis. Free Radical Biol. Med. 20, 707-727
4. Berliner, J. A., Navab, M., Fogelman, A. M., Frank, J. S., Demer, L. L., Edwards, P. A., Watson, A. D. and Lusis, A. J. (1995) Atherosclerosis: basic mechanisms: oxidation, inflammation, and genetics. Circulation 91, 2488-2496
5. Wang, R. U. I. (2002) Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter? FASEB J. 16, 1792-1798
6. Whiteman, M., Cheung, N. S., Zhu, Y.-Z., Chu, S. H., Siau, J. L., Wong, B. S., Armstrong, J. S. and Moore, P. K. (2005) Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? Biochem. Biophys. Res. Commun. 326, 794-798
7. Laggner, H., Muellner, M. K., Schreier, S., Sturm, B., Hermann, M., Exner, M., Gmeiner, B. M. K. and Kapiotis, S. (2007) Hydrogen sulphide: a novel physiological inhibitor of LDL atherogenic modification by HOCl. Free Radical Res. 41, 741-747
8. Devai, I. and Delaune, R. D. (2002) Effectiveness of selected chemicals for controlling emission of malodorous sulfur gases in sewage sludge. Environ. Technol. 23, 319-329
9. Beauchamp, R. J., Bus, J., Popp, J., Boreiko, C. and Andjelkovich, D. A. (1984) A critical review of the literature on hydrogen sulfide toxicity. Crit. Rev. Toxicol. 13, 25-97
10. Hermann, M. and Gmeiner, B. (1992) Altered susceptibility to in vitro oxidation of LDL in LDL complexes and LDL aggregates. Arterioscler. Thromb. 12, 1503-1506
11. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275
12. Gerry, A. B., Satchell, L. and Leake, D. S. (2008) A novel method for production of lipid hydroperoxide- or oxysterol-rich low-density lipoprotein. Atherosclerosis 197, 579-587
13. Nourooz-Zadeh, J., Tajaddini-Sarmadi, J., Ling, K. L. and Wolff, S. P. (1996) Low-density lipoprotein is the major carrier of lipid hydroperoxides in plasma. Relevance to determination of total plasma lipid hydroperoxide concentrations. Biochem. J. 313, 781-786
14. Esterbauer, H., Gebicki, J., Puhl, H. and Jürgens, G. (1992) The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radical Biol. Med. 13, 341-390
15. Laggner, H., Hermann, M., Sturm, B., Gmeiner, B. M. K. and Kapiotis, S. (2005) Sulfite facilitates LDL lipid oxidation by transition metal ions: a pro-oxidant in wine? FEBS Lett. 579, 6486-6492
16. Kapiotis, S., Besemer, J., Bevec, D., Valent, P., Bettelheim, P., Lechner, K. and Speiser, W. (1991) Interleukin-4 counteracts pyrogen-induced downregulation of thrombomodulin in cultured human vascular endothelial cells. Blood 78, 410-415
17. Laggner, H., Hermann, M., Esterbauer, H., Muellner, M. K., Exner, M., Gmeiner, B. M. K. and Kapiotis, S. (2007) The novel gaseous vasorelaxant hydrogen sulfide inhibits angiotensin-converting enzyme activity of endothelial cells. J. Hypertension 25, 2100-2104
18. Thomas, C. E. and Jackson, R. L. (1991) Lipid hydroperoxide involvement in copper-dependent and independent oxidation of low density lipoproteins. J. Pharmacol. Exp. Ther. 256, 1182-1188
19. Frei, B., Yamamoto, Y., Niclas, D. and Ames, B. N. (1988) Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma. Anal. Biochem. 175, 120-130
20. Tang, L., Zhang, Y., Qian, Z. and Shen, X. (2000) The mechanism of Fe(2+)-initiated lipid peroxidation in liposomes: the dual function of ferrous ions, the roles of the pre-existing lipid peroxides and the lipid peroxyl radical. Biochem. J. 352, 27-36
21. Anwar, A. A., Li, F. Y. L., Leake, D. S., Ishii, T., Mann, G. E. and Siow, R. C. M. (2005) Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2. Free Radical Biol. Med. 39, 227-236
22. Agarwal, A., Shiraishi, F., Visner, G. A. and Nick, H. S. (1998) Linoleyl hydroperoxide transcriptionally upregulates heme oxygenase-1 gene expression in human renal epithelial and aortic endothelial cells. J. Am. Soc. Nephrol. 9, 1990-1997
23. Ishikawa, K., Navab, M., Leitinger, N., Fogelman, A. M. and Lusis, A. J. (1997) Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL. J. Clin. Invest. 100, 1209-1216
24. Browne, R. W. and Armstrong, D. (2000) HPLC analysis of lipid-derived polyunsaturated fatty acid peroxidation products in oxidatively modified human plasma. Clin. Chem. 46, 829-836
25. Aviram, M., Billecke, S., Sorenson, R., Bisgaier, C., Newton, R., Rosenblat, M., Erogul, J., Hsu, C., Dunlop, C. and La Du, B. (1998) Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and R. Arterioscler. Thromb. Vasc. Biol. 18, 1617-1624
26. Whiteman, M., Armstrong, J. S., Chu, S. H., Jia-Ling, S., Wong, B.-S., Cheung, N. S., Halliwell, B. and Moore, P. K. (2004) The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'? J. Neurochem. 90, 765-768
27. Spiteller, G. (2006) Peroxyl radicals: inductors of neurodegenerative and other inflammatory diseases. Their origin and how they transform cholesterol, phospholipids, plasmalogens, polyunsaturated fatty acids, sugars, and proteins into deleterious products. Free Radical Biol. Med. 41, 362-387
28. Esterbauer, H., Schaur, R. and Zollner, H. (1991) Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radical Biol. Med. 11, 81-128
29. Spiteller, P., Kern, W., Reiner, J. and Spiteller, G. (2001) Aldehydic lipid peroxidation products derived from linoleic acid. Biochim. Biophys. Acta 1531, 188-208
30. Durrington, P. N., Mackness, B. and Mackness, M. I. (2001) Paraoxonase and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 21, 473-480
31. Aviram, M., Rosenblat, M., Bisgaier, C. L., Newton, R. S., Primo-Parmo, S. L. and La Du, B. N. (1998) Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. J. Clin. Invest. 101, 1581-1590
32. Abe, K. and Kimura, H. (1996) The possible role of hydrogen sulfide as an endogenous neuromodulator. J. Neurosci. 16, 1066-1071
33. Hosoki, R., Matsuki, N. and Kimura, H. (1997) The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. Biochem. Biophys. Res. Commun. 237, 527-531
34. Furne, J., Saeed, A. and Levitt, M. D. (2008) Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295, R1479-R1485
35. Ishigami, M., Hiraki, K., Umemura, K., Ogasawara, Y., Ishii, K. and Kimura, H. (2009) A source of hydrogen sulfide and a mechanism of its release in the brain. Antioxid. Redox Signal. 11, 205-214
36. Heinecke, J. W. (2006) Lipoprotein oxidation in cardiovascular disease: chief culprit or innocent bystander? J. Exp. Med. 203, 813-816
37. 2S as a novel endogenous gaseous K(ATP) channel opener. EMBO J. 20, 6008-6016.