Hyponatremia: Case Vignettes

Seminars in Nephrology

Volumn 29, Issue 3, 2009, Pages 300-317

  Mount, David B ^a   Krahn, Thomas A ^b  

^a VA BOSTON HEALTHCARE SYSTEM   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Beer potomania; conivaptan; DDAVP; hypertonic saline; hypopituitarism; olfactory neuroblastoma; pregnancy; SIADH; thiazide; tolvaptan

Indexed keywords

AMFEBUTAMONE; ATENOLOL; DESIPRAMINE; DESMOPRESSIN; DOCUSATE SODIUM; ENOXAPARIN; FLUOXETINE; GLUCOCORTICOID; HYDROCHLOROTHIAZIDE; HYDROCORTISONE; IBUPROFEN; IRON; LABETALOL; LAMOTRIGINE; LEVOFLOXACIN; LEVOTHYROXINE SODIUM; LORAZEPAM; METRONIDAZOLE; MEVINOLIN; MULTIVITAMIN; OMEPRAZOLE; OXYCODONE; PARACETAMOL; PHENAZOPYRIDINE; PREDNISONE; SODIUM; SODIUM CHLORIDE; SPIRONOLACTONE; THYROXINE; UNINDEXED DRUG;

ACUTE DISEASE; ADULT; ANAMNESIS; ARTICLE; CEREBRAL SALT WASTING; CLINICAL ARTICLE; CLINICAL FEATURE; COLITIS; DEPRESSION; DIZZINESS; ESTHESIONEUROBLASTOMA; FEMALE; GRAND MAL SEIZURE; HOSPITALIZATION; HUMAN; HUMAN TISSUE; HYPERCHOLESTEROLEMIA; HYPERTENSION; HYPONATREMIA; HYPOPHYSIS DISEASE; LABORATORY TEST; MALE; NAUSEA; NEUROSURGERY; PATIENT ASSESSMENT; PHYSICAL EXAMINATION; PRIORITY JOURNAL; RECURRENT DISEASE; SERUM OSMOLALITY; SODIUM BLOOD LEVEL; SYMPTOM; THERAPEUTIC ERROR; URINARY TRACT INFECTION; URINE OSMOLALITY; VOMITING;

ADULT; AGED; BENZAZEPINES; DEAMINO ARGININE VASOPRESSIN; FEMALE; HUMANS; HYPONATREMIA; MALE; MIDDLE AGED; SALINE SOLUTION, HYPERTONIC; TREATMENT OUTCOME;

EID: 66449125657     PISSN: 02709295     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2009.04.001     Document Type: Article

References (74)

1. th ed. (2008), Saunders, Philadelphia, PA 459-546
2. Berl T. Treating hyponatremia: damned if we do and damned if we don't. Kidney Int 37 (1990) 1006-1018
3. Berl T. Impact of solute intake on urine flow and water excretion. J Am Soc Nephrol 19 (2008) 1076-1078
4. Perianayagam A., Sterns R.H., Silver S.M., et al. DDAVP is effective in preventing and reversing inadvertent overcorrection of hyponatremia. Clin J Am Soc Nephrol 3 (2008) 331-336
5. Bagley S.C., and Yaeger D. Hyponatremia associated with bupropion, a case verified by rechallenge. J Clin Psychopharmacol 25 (2005) 98-99
6. Mewasingh L., Aylett S., Kirkham F., and Stanhope R. Hyponatremia associated with lamotrigine in cranial diabetes insipidus. Lancet 356 (2000) 656
7. Hill A.R., Uribarri J., Mann J., and Berl T. Altered water metabolism in tuberculosis: role of vasopressin. Am J Med 88 (1990) 357-364
8. Smith J., and Godwin-Austen R. Hypersecretion of anti-diuretic hormone due to tuberculous meningitis. Postgrad Med J 56 (1980) 41-44
9. Chung H.M., Kluge R., Schrier R.W., and Anderson R.J. Clinical assessment of extracellular fluid volume in hyponatremia. Am J Med 83 (1987) 905-908
10. Milionis H.J., Liamis G.L., and Elisaf M.S. The hyponatremic patient: a systematic approach to laboratory diagnosis. CMAJ 166 (2002) 1056-1062
11. Liamis G.L., Milionis H.J., Rizos E.C., Siamopoulos K.C., and Elisaf M.S. Mechanisms of hyponatraemia in alcohol patients. Alcohol Alcohol 35 (2000) 612-616
12. Sanghvi S.R., Kellerman P.S., and Nanovic L. Beer potomania: an unusual cause of hyponatremia at high risk of complications from rapid correction. Am J Kidney Dis 50 (2007) 673-680
13. Musch W., Xhaet O., and Decaux G. Solute loss plays a major role in polydipsia-related hyponatremia of both water drinkers and beer drinkers. Q J Med 96 (2003) 421-426
14. Thaler S.M., Teitelbaum I., and Berl T. "Beer potomania" in non-beer drinkers: effect of low dietary solute intake. Am J Kidney Dis 31 (1998) 1028-1031
15. Rosenbaum J.D., Nelson III W.P., Strauss M.B., Davis R.K., and Rossmeisl E.C. Variation in the diuretic response to ingested water related to the renal excretion of solutes. J Clin Invest 32 (1953) 394-404
16. Rose B.D. New approach to disturbances in the plasma sodium concentration. Am J Med 81 (1986) 1033-1040
17. Hilden T., and Svendsen T.L. Electrolyte disturbances in beer drinkers. A specific "hypo-osmolality syndrome.". Lancet 2 (1975) 245-246
18. Davison J.M., Shiells E.A., Philips P.R., and Lindheimer M.D. Serial evaluation of vasopressin release and thirst in human pregnancy. Role of human chorionic gonadotrophin in the osmoregulatory changes of gestation. J Clin Invest 81 (1988) 798-806
19. Hayslett J.P., Katz D.L., and Knudson J.M. Dilutional hyponatremia in pre-eclampsia. Am J Obstet Gynecol 179 (1998) 1312-1316
20. Dokmetas H.S., Kilicli F., Korkmaz S., and Yonem O. Characteristic features of 20 patients with Sheehan's syndrome. Gynecol Endocrinol 22 (2006) 279-283
21. Fichman M.P., Vorherr H., Kleeman C.R., and Telfer N. Diuretic-induced hyponatremia. Ann Intern Med 75 (1971) 853-863
22. Sharabi Y., Illan R., Kamari Y., et al. Diuretic induced hyponatremia in elderly hypertensive women. J Hum Hypertens 16 (2002) 631-635
23. Friedman E., Shadel M., Halkin H., and Farfel Z. Thiazide-induced hyponatremia. Reproducibility by single dose rechallenge and an analysis of pathogenesis. Ann Intern Med 110 (1989) 24-30
24. Berl T., Linas S.L., Aisenbrey G.A., and Anderson R.J. On the mechanism of polyuria in potassium depletion. The role of polydipsia. J Clin Invest 60 (1977) 620-625
25. Morris R.G., Hoorn E.J., and Knepper M.A. Hypokalemia in a mouse model of Gitelman's syndrome. Am J Physiol Renal Physiol 290 (2006) F1416-F1420
26. Cesar K.R., and Magaldi A.J. Thiazide induces water absorption in the inner medullary collecting duct of normal and Brattleboro rats. Am J Physiol 277 (1999) F756-F760
27. Kim G.H., Lee J.W., Oh Y.K., et al. Antidiuretic effect of hydrochlorothiazide in lithium-induced nephrogenic diabetes insipidus is associated with upregulation of aquaporin-2, Na-Cl co-transporter, and epithelial sodium channel. J Am Soc Nephrol 15 (2004) 2836-2843
28. Clark B.A., Shannon R.P., Rosa R.M., and Epstein F.H. Increased susceptibility to thiazide-induced hyponatremia in the elderly. J Am Soc Nephrol 5 (1994) 1106-1111
29. Rao R., Zhang M.Z., Zhao M., et al. Lithium treatment inhibits renal GSK-3 activity and promotes cyclooxygenase 2-dependent polyuria. Am J Physiol Renal Physiol 288 (2005) F642-F649
30. Norregaard R., Jensen B.L., Li C., et al. COX-2 inhibition prevents downregulation of key renal water and sodium transport proteins in response to bilateral ureteral obstruction. Am J Physiol Renal Physiol 289 (2005) F322-F333
31. Plasencia Y.L., Cortes M.B., Arencibia D.M., et al. Esthesioneuroblastoma recurrence presenting as a syndrome of inappropriate antidiuretic hormone secretion. Head Neck 28 (2006) 1142-1146
32. Osterman J., Calhoun A., Dunham M., et al. Chronic syndrome of inappropriate antidiuretic hormone secretion and hypertension in a patient with olfactory neuroblastoma. Evidence of ectopic production of arginine vasopressin by the tumor. Arch Intern Med 146 (1986) 1731-1735
33. Cullen M.J., Cusack D.A., O'Briain D.S., Devlin J.B., Kehely A., and Lyons T.A. Neurosecretion of arginine vasopressin by an olfactory neuroblastoma causing reversible syndrome of antidiuresis. Am J Med 81 (1986) 911-916
34. Renneboog B., and Decaux G. Idiopathic hyponatremia in a young patient: look at the sinus. Am J Med 121 (2008) e5-e6
35. Ma A.T., and Lei K.I. Small cell neuroendocrine carcinoma of the ethmoid sinuses presenting with generalized seizure and syndrome of inappropriate antidiuretic hormone secretion: a case report and review of literature. Am J Otolaryngol 30 (2009) 54-57
36. Vasan N.R., Medina J.E., Canfield V.A., and Gillies E.M. Sinonasal neuroendocrine carcinoma in association with SIADH. Head Neck 26 (2004) 89-93
37. List A.F., Hainsworth J.D., Davis B.W., Hande K.R., Greco F.A., and Johnson D.H. The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in small-cell lung cancer. J Clin Oncol 4 (1986) 1191-1198
38. Ellison D.H., and Berl T. Clinical practice. The syndrome of inappropriate antidiuresis. N Engl J Med 356 (2007) 2064-2072
39. Ferlito A., Rinaldo A., and Devaney K.O. Syndrome of inappropriate antidiuretic hormone secretion associated with head neck cancers: review of the literature. Ann Otol Rhinol Laryngol 106 (1997) 878-883
40. Anpalahan M. Chronic idiopathic hyponatremia in older people due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) possibly related to aging. J Am Geriatr. Soc 49 (2001) 788-792
41. Decaux G., Vandergheynst F., Bouko Y., Parma J., Vassart G., and Vilain C. Nephrogenic syndrome of inappropriate antidiuresis in adults: high phenotypic variability in men and women from a large pedigree. J Am Soc Nephrol 18 (2007) 606-612
42. Grantham J.J., and Orloff J. Effect of prostaglandin E1 on the permeability response of the isolated collecting tubule to vasopressin, adenosine 3′,5′-monophosphate, and theophylline. J Clin Invest 47 (1968) 1154-1161
43. Fernandez-Llama P., Ecelbarger C.A., Ware J.A., et al. Cyclooxygenase inhibitors increase Na-K-2Cl cotransporter abundance in thick ascending limb of Henle's loop. Am J Physiol 277 (1999) F219-F226
44. Sun R., Carlson N.G., Hemmert A.C., and Kishore B.K. P2Y2 receptor-mediated release of prostaglandin E2 by IMCD is altered in hydrated and dehydrated rats: relevance to AVP-independent regulation of IMCD function. Am J Physiol Renal Physiol 289 (2005) F585-F592
45. Wharam P.C., Speedy D.B., Noakes T.D., Thompson J.M., Reid S.A., and Holtzhausen L.M. NSAID use increases the risk of developing hyponatremia during an Ironman triathlon. Med Sci Sports Exerc 38 (2006) 618-622
46. Fraser C.L., and Arieff A.I. Epidemiology, pathophysiology, and management of hyponatremic encephalopathy. Am J Med 102 (1997) 67-77
47. Ayus J.C., and Arieff A.I. Pulmonary complications of hyponatremic encephalopathy. Noncardiogenic pulmonary edema and hypercapnic respiratory failure. Chest 107 (1995) 517-521
48. Kalantar-Zadeh K., Nguyen M.K., Chang R., and Kurtz I. Fatal hyponatremia in a young woman after ecstasy ingestion. Nat Clin Pract Nephrol 2 (2006) 283-288 quiz 9
49. Siegel A.J., Verbalis J.G., Clement S., et al. Hyponatremia in marathon runners due to inappropriate arginine vasopressin secretion. Am J Med 120 (2007) 461e11-7
50. Janicic N., and Verbalis J.G. Evaluation and management of hypo-osmolality in hospitalized patients. Endocrinol Metab Clin North Am 32 (2003) 459-481 vii
51. Mohmand H.K., Issa D., Ahmad Z., Cappuccio J.D., Kouides R.W., and Sterns R.H. Hypertonic saline for hyponatremia: risk of inadvertent overcorrection. Clin J Am Soc Nephrol 2 (2007) 1110-1117
52. Lauriat S.M., and Berl T. The hyponatremic patient: practical focus on therapy. J Am Soc Nephrol 8 (1997) 1599-1607
53. Soupart A., Penninckx R., Stenuit A., Perier O., and Decaux G. Reinduction of hyponatremia improves survival in rats with myelinolysis-related neurologic symptoms. J Neuropathol Exp Neurol 55 (1996) 594-601
54. Soupart A., Penninckx R., Crenier L., Stenuit A., Perier O., and Decaux G. Prevention of brain demyelination in rats after excessive correction of chronic hyponatremia by serum sodium lowering. Kidney Int 45 (1994) 193-200
55. Soupart A., Ngassa M., and Decaux G. Therapeutic relowering of the serum sodium in a patient after excessive correction of hyponatremia. Clin Nephrol 51 (1999) 383-386
56. Oya S., Tsutsumi K., Ueki K., and Kirino T. Reinduction of hyponatremia to treat central pontine myelinolysis. Neurology 57 (2001) 1931-1932
57. Goldszmidt M.A., and Iliescu E.A. DDAVP to prevent rapid correction in hyponatremia. Clin Nephrol 53 (2000) 226-229
58. Smith T.J., Gill J.C., Ambruso D.R., and Hathaway W.E. Hyponatremia and seizures in young children given DDAVP. Am J Hematol 31 (1989) 199-202
59. Odeh M., and Oliven A. Coma and seizures due to severe hyponatremia and water intoxication in an adult with intranasal desmopressin therapy for nocturnal enuresis. J Clin Pharmacol 41 (2001) 582-584
60. Pruthi R.S., Kang J., and Vick R. Desmopressin induced hyponatremia and seizures after laparoscopic radical nephrectomy. J Urol 168 (2002) 187
61. Dehoorne J.L., Raes A.M., van Laecke E., Hoebeke P., and Vande Walle J.G. Desmopressin toxicity due to prolonged half-life in 18 patients with nocturnal enuresis. J Urol 176 (2006) 754-757 discussion 7-8
62. Rembratt A., Graugaard-Jensen C., Senderovitz T., Norgaard J.P., and Djurhuus J.C. Pharmacokinetics and pharmacodynamics of desmopressin administered orally versus intravenously at daytime versus night-time in healthy men aged 55-70 years. Eur J Clin Pharmacol 60 (2004) 397-402
63. Fjellestad-Paulsen A., Hoglund P., Lundin S., and Paulsen O. Pharmacokinetics of 1-deamino-8-D-arginine vasopressin after various routes of administration in healthy volunteers. Clin Endocrinol (Oxf) 38 (1993) 177-182
64. Diederich S., Franzen N.F., Bahr V., and Oelkers W. Severe hyponatremia due to hypopituitarism with adrenal insufficiency: report on 28 cases. Eur J Endocrinol 148 (2003) 609-617
65. Raff H. Glucocorticoid inhibition of neurohypophysial vasopressin secretion. Am J Physiol 252 (1987) R635-R644
66. Erkut Z.A., Pool C., and Swaab D.F. Glucocorticoids suppress corticotropin-releasing hormone and vasopressin expression in human hypothalamic neurons. J Clin Endocrinol Metab 83 (1998) 2066-2073
67. Saito T., Ishikawa S.E., Ando F., Higashiyama M., Nagasaka S., and Sasaki S. Vasopressin-dependent upregulation of aquaporin-2 gene expression in glucocorticoid-deficient rats. Am J Physiol Renal Physiol 279 (2000) F502-F508
68. Wang W., Li C., Summer S.N., et al. Molecular analysis of impaired urinary diluting capacity in glucocorticoid deficiency. Am J Physiol Renal Physiol 290 (2006) F1135-F1142
69. Kamoi K., Tamura T., Tanaka K., Ishibashi M., and Yamaji T. Hyponatremia and osmoregulation of thirst and vasopressin secretion in patients with adrenal insufficiency. J Clin Endocrinol Metab 77 (1993) 1584-1588
70. Agus Z.S., and Goldberg M. Role of antidiuretic hormone in the abnormal water diuresis of anterior hypopituitarism in man. J Clin Invest 50 (1971) 1478-1489
71. Shoji M., Kimura T., Ota K., et al. Cortical laminar necrosis and central pontine myelinolysis in a patient with Sheehan syndrome and severe hyponatremia. Intern Med 35 (1996) 427-431
72. Lasheen I., Doi S.A., and Al-Shoumer K.A. Glucocorticoid replacement in panhypopituitarism complicated by myelinolysis. Med Princ Pract 14 (2005) 115-117
73. Schrier R.W., Gross P., Gheorghiade M., et al. Tolvaptan, a selective oral vasopressin V2-receptor antagonist, for hyponatremia. N Engl J Med 355 (2006) 2099-2112
74. Zeltser D., Rosansky S., van Rensburg H., Verbalis J.G., and Smith N. Assessment of the efficacy and safety of intravenous conivaptan in euvolemic and hypervolemic hyponatremia. Am J Nephrol 27 (2007) 447-457