-
1
-
-
34247480545
-
Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition
-
DOI 10.1038/nrc2106, PII NRC2106
-
Force T, Krause DS, Van Etten RA. Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nat Rev Cancer 2007; 7: 332-344 (Pubitemid 46652481)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.5
, pp. 332-344
-
-
Force, T.1
Krause, D.S.2
Van Etten, R.A.3
-
2
-
-
67149138802
-
Terapia celowana Czȩść I. Mechanizmy przesyłania sygnałów przy udziale receptorów o aktywności kinazy tyrozynowej
-
Wiczyńska B, Rolski J. Terapia celowana Czȩść I. Mechanizmy przesyłania sygnałów przy udziale receptorów o aktywności kinazy tyrozynowej. Współcz Onkol 2007; 11: 331-6.
-
(2007)
Współcz Onkol
, vol.11
, pp. 331-336
-
-
Wiczyńska, B.1
Rolski, J.2
-
3
-
-
22044442973
-
Tyrosine kinases as targets for cancer therapy
-
DOI 10.1056/NEJMra044389
-
Krause DS, Van Etten RA. Tyrosine kinases as targets for cancer therapy. N Engl J Med 2005; 353: 172-187 (Pubitemid 41058349)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.2
, pp. 172-187
-
-
Krause, D.S.1
Van Etten, R.A.2
-
4
-
-
33746845181
-
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
-
DOI 10.1038/nm1446, PII NM1446
-
Kerkelä R, Grazette L, Yacobi R, et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 2006; 12: 908-916 (Pubitemid 44175142)
-
(2006)
Nature Medicine
, vol.12
, Issue.8
, pp. 908-916
-
-
Kerkela, R.1
Grazette, L.2
Yacobi, R.3
Iliescu, C.4
Patten, R.5
Beahm, C.6
Walters, B.7
Shevtsov, S.8
Pesant, S.9
Clubb, F.J.10
Rosenzweig, A.11
Salomon, R.N.12
Van Etten, R.A.13
Alroy, J.14
Durand, J.-B.15
Force, T.16
-
5
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
DOI 10.1056/NEJMoa065044
-
Motzer RJ, Hutson TE, Tomczak P, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007; 356: 115-124 (Pubitemid 46089672)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
6
-
-
33745204925
-
AMPK alterations in cardiac physiology and pathology: Enemy or ally?
-
Dyck JR, Lopaschuk GD. AMPK alterations in cardiac physiology and pathology: enemy or ally? J Physiol 2006; 574: 95-112.
-
(2006)
J Physiol
, vol.574
, pp. 95-112
-
-
Dyck, J.R.1
Lopaschuk, G.D.2
-
7
-
-
24944591333
-
Multi-kinase inhibitors create buzz at ASCO
-
Branca MA. Multi-kinase inhibitors create buzz at ASCO. Nat Biotechnol 2005; 23: 639.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 639
-
-
Branca, M.A.1
-
9
-
-
33749505836
-
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: A randomised controlled trial
-
Demetri GD, van Oosterom AT, Garrett CR, et al. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet 2006; 368: 1329-38.
-
(2006)
Lancet
, vol.368
, pp. 1329-1338
-
-
Demetri, G.D.1
Van Oosterom, A.T.2
Garrett, C.R.3
-
10
-
-
33750961647
-
Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors
-
Desai J, Yassa L, Marqusee E, et al. Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors. Ann Intern Med 2006; 145: 660-664 (Pubitemid 46768841)
-
(2006)
Annals of Internal Medicine
, vol.145
, Issue.9
, pp. 660-664
-
-
Desai, J.1
Yassa, L.2
Marqusee, E.3
George, S.4
Frates, M.C.5
Chen, M.H.6
Morgan, J.A.7
Dychter, S.S.8
Larsen, P.R.9
Demetri, G.D.10
Alexander, E.K.11
-
11
-
-
33747416695
-
Local controlled intramyocardial delivery of platelet-derived growth factor improves postinfarction ventricular function without pulmonary toxicity
-
DOI 10.1161/CIRCULATIONAHA.106.639831, PII 0000301720060815000007
-
Hsieh PC, MacGillivray C, Gannon J, Cruz FU, Lee RT. Local controlled intramyocardial delivery of platelet-derived growth factor improves postinfarction ventricular function without pulmonary toxicity. Circulation 2006; 114: 637-644 (Pubitemid 44252305)
-
(2006)
Circulation
, vol.114
, Issue.7
, pp. 637-644
-
-
Hsieh, P.C.H.1
MacGillivray, C.2
Gannon, J.3
Cruz, F.U.4
Lee, R.T.5
-
12
-
-
27144489669
-
AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress
-
DOI 10.1128/MCB.25.21.9554-9575.2005
-
Terai K, Hiramoto Y, Masaki M, Sugiyama S, Kuroda T, Hori M, Kawase I, Hirota H. AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress. Mol Cell Biol 2005; 25: 9554-9575 (Pubitemid 41507855)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.21
, pp. 9554-9575
-
-
Terai, K.1
Hiramoto, Y.2
Masaki, M.3
Sugiyama, S.4
Kuroda, T.5
Hori, M.6
Kawase, I.7
Hirota, H.8
-
13
-
-
19744365702
-
A small molecule-kinase interaction map for clinical kinase inhibitors
-
Fabian MA, Biggs WH 3rd, Treiber DK, et al. A small molecule-kinase interaction map for clinical kinase inhibitors. Nat Biotechnol 2005; 23: 329-36.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 329-336
-
-
Fabian, M.A.1
Biggs III, W.H.2
Treiber, D.K.3
-
14
-
-
33750303156
-
-
Bayer Pharmaceuticals. Available at
-
Bayer Pharmaceuticals. Nexavar (sorafenib) Prescribing Information. Available at: 〈http://www. univgraph. com/ bayer/inserts/nexavar. pdf〉(2006).
-
(2006)
Nexavar (Sorafenib) Prescribing Information
-
-
-
15
-
-
0034944380
-
Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism
-
DOI 10.1073/pnas.141224398
-
Chen J, Fujii K, Zhang L, Roberts T, Fu H. Raf-1 promotes cell survival by antagonizing apoptosis signal-regulated kinase 1 through a MEK-ERK independent mechanism. Proc Natl Acad Sci U S A 2001; 98: 7783-7788 (Pubitemid 32642638)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.14
, pp. 7783-7788
-
-
Chen, J.1
Fujii, K.2
Zhang, L.3
Roberts, T.4
Fu, H.5
-
16
-
-
25144434834
-
Role of raf proteins in cardiac hypertrophy and cardiomyocyte survival
-
Muslin AJ. Role of raf proteins in cardiac hypertrophy and cardiomyocyte survival. Trends Cardiovasc Med 2005; 15: 225-9.
-
(2005)
Trends Cardiovasc Med
, vol.15
, pp. 225-229
-
-
Muslin, A.J.1
-
17
-
-
9144231898
-
Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling
-
Yamaguchi O, Higuchi Y, Hirotani S, et al. Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling. Proc Natl Acad Sci U S A 2003; 100: 15883-8.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15883-15888
-
-
Yamaguchi, O.1
Higuchi, Y.2
Hirotani, S.3
-
18
-
-
9644295769
-
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis
-
Yamaguchi O, Watanabe T, Nishida K, et al. Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis. J Clin Invest 2004; 114: 937-43.
-
(2004)
J Clin Invest
, vol.114
, pp. 937-943
-
-
Yamaguchi, O.1
Watanabe, T.2
Nishida, K.3
-
19
-
-
4043076222
-
Raf-1 kinase is required for cardiac hypertrophy and cardiomyocyte survival in response to pressure overload
-
DOI 10.1161/01.CIR.0000138190.50127.6A
-
Harris IS, Zhang S, Treskov I, Kovacs A, Weinheimer C, Muslin AJ. Raf- -1 kinase is required for cardiac hypertrophy and cardiomyocyte survival in response to pressure overload. Circulation 2004; 110: 718-723 (Pubitemid 39056272)
-
(2004)
Circulation
, vol.110
, Issue.6
, pp. 718-723
-
-
Harris, I.S.1
Zhang, S.2
Treskov, I.3
Kovacs, A.4
Weinheimer, C.5
Muslin, A.J.6
-
20
-
-
23644439061
-
Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure
-
DOI 10.1172/JCI24682
-
Shiojima I, Sato K, Izumiya Y, Schiekofer S, Ito M, Liao R, Colucci WS, Walsh K. Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure. J Clin Invest 2005; 115: 2108-2118 (Pubitemid 41134152)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.8
, pp. 2108-2118
-
-
Shiojima, I.1
Sato, K.2
Izumiya, Y.3
Schiekofer, S.4
Ito, M.5
Liao, R.6
Colucci, W.S.7
Walsh, K.8
-
21
-
-
33646149385
-
Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload
-
DOI 10.1161/01.HYP.0000215207.54689.31, PII 0000426820060500000018
-
Izumiya Y, Shiojima I, Sato K, Sawyer DB, Colucci WS, Walsh K. Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload. Hypertension 2006; 47: 887-893 (Pubitemid 44297560)
-
(2006)
Hypertension
, vol.47
, Issue.5
, pp. 887-893
-
-
Izumiya, Y.1
Shiojima, I.2
Sato, K.3
Sawyer, D.B.4
Colucci, W.S.5
Walsh, K.6
-
22
-
-
33947520124
-
p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
-
Sano M, Minamino T, Toko H, et al. p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. Nature 2007; 446: 444-8.
-
(2007)
Nature
, vol.446
, pp. 444-448
-
-
Sano, M.1
Minamino, T.2
Toko, H.3
-
23
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
DOI 10.1038/nature05541, PII NATURE05541
-
Ventura A, Kirsch DG, McLaughlin ME, et al. Restoration of p53 function leads to tumour regression in vivo. Nature 2007; 445: 661-665 (Pubitemid 46232887)
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
Tuveson, D.A.4
Grimm, J.5
Lintault, L.6
Newman, J.7
Reczek, E.E.8
Weissleder, R.9
Jacks, T.10
-
24
-
-
38549085315
-
Incidence and risk of hypertension with sorafenib in patients with cancer: A systematic review and meta-analysis
-
Wu S, Chen JJ, Kudelka A, Lu J, Zhu X. Incidence and risk of hypertension with sorafenib in patients with cancer: a systematic review and meta-analysis. Lancet Oncol 2008; 9: 117-23.
-
(2008)
Lancet Oncol
, vol.9
, pp. 117-123
-
-
Wu, S.1
Chen, J.J.2
Kudelka, A.3
Lu, J.4
Zhu, X.5
-
25
-
-
38549173724
-
The Advanced Renal Cell Carcinoma Sorafenib (ARCCS) expanded access trial in North America: Safety and efficacy
-
abstract 5011
-
Figlin R, McDermott D, Gabrail N, et al. The Advanced Renal Cell Carcinoma Sorafenib (ARCCS) expanded access trial in North America: safety and efficacy. Proc Am Soc Clin Oncol 2007; 25: (abstract 5011).
-
(2007)
Proc Am Soc Clin Oncol
, vol.25
-
-
Figlin, R.1
McDermott, D.2
Gabrail, N.3
-
26
-
-
33744984843
-
Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.03.6723
-
Ratain MJ, Eisen T, Stadler WM, et al. Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol 2006; 24: 2505-2512 (Pubitemid 46630627)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.16
, pp. 2505-2512
-
-
Ratain, M.J.1
Eisen, T.2
Stadler, W.M.3
Flaherty, K.T.4
Kaye, S.B.5
Rosner, G.L.6
Gore, M.7
Desai, A.A.8
Patnaik, A.9
Xiong, H.Q.10
Rowinsky, E.11
Abbruzzese, J.L.12
Xia, C.13
Simantov, R.14
Schwartz, B.15
O'Dwyer, P.J.16
-
27
-
-
6044274062
-
Cardiovascular complications of cancer therapy: Diagnosis, pathogenesis, and management
-
Yeh ET, Tong AT, Lenihan DJ, et al. Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management. Circulation 2004; 109: 3122-31.
-
(2004)
Circulation
, vol.109
, pp. 3122-3131
-
-
Yeh, E.T.1
Tong, A.T.2
Lenihan, D.J.3
-
28
-
-
33846638744
-
Risks of Proteinuria and Hypertension with Bevacizumab, an Antibody Against Vascular Endothelial Growth Factor: Systematic Review and Meta-Analysis
-
DOI 10.1053/j.ajkd.2006.11.039, PII S0272638606018336
-
Zhu X, Wu S, Dahut WL, Parikh CR. Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: systematic review and meta-analysis. Am J Kidney Dis 2007; 49: 186-193 (Pubitemid 46178407)
-
(2007)
American Journal of Kidney Diseases
, vol.49
, Issue.2
, pp. 186-193
-
-
Zhu, X.1
Wu, S.2
Dahut, W.L.3
Parikh, C.R.4
-
29
-
-
0242468884
-
A Phase I/II Dose-Escalation Trial of Bevacizumab in Previously Treated Metastatic Breast Cancer
-
Cobleigh MA, Langmuir VK, Sledge GW, Miller KD, Haney L, Novotny WF, Reimann JD, Vassel A. A phase I/II doseescalation trial of bevacizumab in previously treated metastatic breast cancer. Semin Oncol 2003; 30 (5 Suppl. 16): 117-124 (Pubitemid 37433402)
-
(2003)
Seminars in Oncology
, vol.30
, Issue.5 SUPPL. 16
, pp. 117-124
-
-
Cobleigh, M.A.1
Langmuir, V.K.2
Sledge, G.W.3
Miller, K.D.4
Haney, L.5
Novotny, W.F.6
Reimann, J.D.7
Vassel, A.8
-
30
-
-
0027082709
-
Hypercholesterolemia after chemotherapy for testis cancer
-
Raghavan D, Cox K, Childs A, Grygiel J, Sullivan D. Hypercholesterolemia after chemotherapy for testis cancer. J Clin Oncol 1992; 10: 1386-9.
-
(1992)
J Clin Oncol
, vol.10
, pp. 1386-1389
-
-
Raghavan, D.1
Cox, K.2
Childs, A.3
Grygiel, J.4
Sullivan, D.5
-
31
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007; 357: 2666-76.
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
32
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987; 235: 177-82.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
33
-
-
0036099675
-
ErbB2 is essential in the prevention of dilated cardiomyopathy
-
DOI 10.1038/nm0502-459
-
Crone SA., Zhao YY, Fan L, et al. ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med 2002; 8: 459-465 (Pubitemid 34546747)
-
(2002)
Nature Medicine
, vol.8
, Issue.5
, pp. 459-465
-
-
Crone, S.A.1
Zhao, Y.-Y.2
Fan, L.3
Gu, Y.4
Minamisawa, S.5
Liu, Y.6
Peterson, K.L.7
Chen, J.8
Kahn, R.9
Condorelli, G.10
Ross Jr., J.11
Chien, K.R.12
Lee, K.-F.13
-
34
-
-
0033520388
-
Stress pathways and heart failure
-
Chien KR. Stress pathways and heart failure. Cell 1999; 98: 555-8.
-
(1999)
Cell
, vol.98
, pp. 555-558
-
-
Chien, K.R.1
-
35
-
-
0032562770
-
Neuregulins promote survival and growth of cardiac myocytes: Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
-
DOI 10.1074/jbc.273.17.10261
-
Zhao YY, Sawyer DR, Baliga RR, Opel DJ, Han X, Marchionni MA, Kelly RA.. Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem 1998; 273: 10261-10269 (Pubitemid 28227629)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.17
, pp. 10261-10269
-
-
Zhao, Y.-Y.1
Sawyer, D.R.2
Baliga, R.R.3
Opel, D.J.4
Han, X.5
Marchionni, M.A.6
Kelly, R.A.7
-
36
-
-
33746048823
-
Neuregulin activates erbB2-dependent src/FAK signaling and cytoskeletal remodeling in isolated adult rat cardiac myocytes
-
DOI 10.1016/j.yjmcc.2006.04.007, PII S0022282806005347
-
Kuramochi Y, Guo X, Sawyer DB. Neuregulin activates ERBB2-dependent Src/FAK signaling and cytoskeletal remodeling in isolated adult rat cardiac myocytes. J Mol Cell Cardiol 2006; 41: 228-235 (Pubitemid 44080212)
-
(2006)
Journal of Molecular and Cellular Cardiology
, vol.41
, Issue.2
, pp. 228-235
-
-
Kuramochi, Y.1
Guo, X.2
Sawyer, D.B.3
-
37
-
-
0028884413
-
Requirement for neuregulin receptor erbB2 in neural and cardiac development
-
Lee KF, Simon H, Chen H, Bates B, Hung MC, Hauser C. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 1995; 378: 394-8.
-
(1995)
Nature
, vol.378
, pp. 394-398
-
-
Lee, K.F.1
Simon, H.2
Chen, H.3
Bates, B.4
Hung, M.C.5
Hauser, C.6
-
38
-
-
0028785406
-
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
-
Gassmann M, Casagranda F, Orioli D, Simon H, Lai C, Klein R, Lemke G. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 1995; 378: 390-4.
-
(1995)
Nature
, vol.378
, pp. 390-394
-
-
Gassmann, M.1
Casagranda, F.2
Orioli, D.3
Simon, H.4
Lai, C.5
Klein, R.6
Lemke, G.7
-
39
-
-
0028827104
-
Multiple essential functions of neuregulin in development
-
Meyer D, Birchmeier C. Multiple essential functions of neuregulin in development. Nature 1995; 378: 386-90.
-
(1995)
Nature
, vol.378
, pp. 386-390
-
-
Meyer, D.1
Birchmeier, C.2
-
40
-
-
0037172982
-
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
-
DOI 10.1073/pnas.122249299
-
Ozcelik C, Erdmann B, Pilz B, et al. Conditional mutation of the Erb- B2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Proc Natl Acad Sci U S A 2002; 99: 8880-8885 (Pubitemid 34693652)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.13
, pp. 8880-8885
-
-
Ozcelik, C.1
Erdmann, B.2
Pilz, B.3
Wettschureck, N.4
Britsch, S.5
Hubner, N.6
Chien, K.R.7
Birchmeier, C.8
Garratt, A.N.9
-
41
-
-
33747377549
-
Trastuzumab in combination with heregulin-activated Her-2 (erbB-2) triggers a receptor-enhanced chemosensitivity effect in the absence of Her-2 overexpression
-
DOI 10.1200/JCO.2005.04.3489
-
Menendez JA, Mehmi I, Lupu R. Trastuzumab in combination with heregulin-activated Her-2 (erbB-2) triggers a receptor-enhanced chemosensitivity effect in the absence of Her-2 overexpression. J Clin Oncol 2006; 24: 3735-3746 (Pubitemid 46622312)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.23
, pp. 3735-3746
-
-
Menendez, J.A.1
Mehmi, I.2
Lupu, R.3
-
42
-
-
9644310269
-
Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: Implications for herceptin-induced cardiomyopathy
-
DOI 10.1016/j.jacc.2004.08.066, PII S0735109704017590
-
Grazette LP, Boecker W, Matsui T, Semigran M, Force TL, Hajjar RJ, Rosenzweig A. Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathy. J Am Coll Cardiol 2004; 44: 2231-2238 (Pubitemid 39576044)
-
(2004)
Journal of the American College of Cardiology
, vol.44
, Issue.11
, pp. 2231-2238
-
-
Grazette, L.P.1
Boecker, W.2
Matsui, T.3
Semigran, M.4
Force, T.L.5
Hajjar, R.J.6
Rosenzweig, A.7
-
43
-
-
34548132413
-
Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: Implications for therapy of heart failure
-
DOI 10.1161/CIRCULATIONAHA.107.690487, PII 0000301720070821000013
-
Lemmens K, Doggen K, De Keulenaer GW. Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failure. Circulation 2007; 116: 954-960 (Pubitemid 47300920)
-
(2007)
Circulation
, vol.116
, Issue.8
, pp. 954-960
-
-
Lemmens, K.1
Doggen, K.2
De Keulenaer, G.W.3
-
45
-
-
71049165197
-
Direct evidence for activation of the neuregulin-1/ErbB system in myocardium of dogs with pacing-induced heart failure
-
Doggen K, Ray L, Mathieu M, Mc Entee K, Lemmens K, De Keulenaer GW. Direct evidence for activation of the neuregulin-1/ErbB system in myocardium of dogs with pacing-induced heart failure. European Congress of Heart Failure, Milan 2008.
-
European Congress of Heart Failure, Milan 2008
-
-
Doggen, K.1
Ray, L.2
Mathieu, M.3
Mc Entee, K.4
Lemmens, K.5
De Keulenaer, G.W.6
-
46
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against her2 for metastatic breast cancer that overexpresses HER2
-
DOI 10.1056/NEJM200103153441101
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344: 783-792 (Pubitemid 32222155)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
-
47
-
-
0036498781
-
Cardiac dysfunction in the trastuzumab clinical trials experience
-
DOI 10.1200/JCO.20.5.1215
-
Seidman A, Hudis C, Pierri MK, et al. Cardiac dysfunction in the trastuzumab clinical trials experience. J Clin Oncol 2002; 20: 1215-1221 (Pubitemid 34177427)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.5
, pp. 1215-1221
-
-
Seidman, A.1
Hudis, C.2
Kathryn Pierri, M.3
Shak, S.4
Paton, V.5
Ashby, M.6
Murphy, M.7
Stewart, S.J.8
Keefe, D.9
-
48
-
-
33748525213
-
Adjuvant therapy with trastuzumab for HER-2/neu-positive breast cancer
-
DOI 10.1634/theoncologist.11-8-857
-
Gonzalez-Angulo AM, Hortobágyi GN, Esteva FJ. Adjuvant therapy with trastuzumab for HER-2/neu-positive breast cancer. Oncologist 2006; 11: 857-867 (Pubitemid 44373758)
-
(2006)
Oncologist
, vol.11
, Issue.8
, pp. 857-867
-
-
Gonzalez-Angulo, A.M.1
Hortobagyi, G.N.2
Esteva, F.J.3
-
49
-
-
29744442709
-
Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in nodepositive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31
-
Tan-Chiu E, Yothers G, Romond E, et al. Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in nodepositive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31. J Clin Oncol 2005; 23: 7811-9.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7811-7819
-
-
Tan-Chiu, E.1
Yothers, G.2
Romond, E.3
-
50
-
-
33645748115
-
Cardiac toxicity of trastuzumab in metastatic breast cancer patients previously treated with high-dose chemotherapy: A retrospective study
-
Bengala C, Zamagni C, Pedrazzoli P, et al. Cardiac toxicity of trastuzumab in metastatic breast cancer patients previously treated with high-dose chemotherapy: a retrospective study. Br J Cancer 2006; 94: 1016-20.
-
(2006)
Br J Cancer
, vol.94
, pp. 1016-1020
-
-
Bengala, C.1
Zamagni, C.2
Pedrazzoli, P.3
-
51
-
-
34548531901
-
Trastuzumab-associated cardiac adverse effects in the herceptin adjuvant trial
-
Suter TM, Procter M, van Veldhuisen DJ, et al. Trastuzumab-associated cardiac adverse effects in the herceptin adjuvant trial. J Clin Oncol 2007; 25: 3859-65.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3859-3865
-
-
Suter, T.M.1
Procter, M.2
Van Veldhuisen, D.J.3
-
52
-
-
32144448027
-
Reversibility of trastuzumab-related cardiotoxicity: New insights based on clinical course and response to medical treatment
-
DOI 10.1200/JCO.2005.13.300
-
Ewer MS, Vooletich MT, Durand JB, Woods ML, Davis JR, Valero V, Lenihan DJ. Reversibility of trastuzumab-related cardiotoxicity: new insights based on clinical course and response to medical treatment. J Clin Oncol 2005; 23: 7820-7826 (Pubitemid 46657379)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.31
, pp. 7820-7826
-
-
Ewer, M.S.1
Vooletich, M.T.2
Durand, J.-B.3
Woods, M.L.4
Davis, J.R.5
Valero, V.6
Lenihan, D.J.7
-
53
-
-
1342311012
-
Clinical cardiac tolerability of trastuzumab
-
Perez EA, Rodeheffer R. Clinical cardiac tolerability of trastuzumab. J Clin Oncol 2004; 22: 322-9.
-
(2004)
J Clin Oncol
, vol.22
, pp. 322-329
-
-
Perez, E.A.1
Rodeheffer, R.2
-
54
-
-
33745008604
-
Pathogenesis of cardiotoxicity induced by anthracyclines
-
Elliott P. Pathogenesis of cardiotoxicity induced by anthracyclines. Semin Oncol 2006; 33: S2-S7.
-
(2006)
Semin Oncol
, vol.33
-
-
Elliott, P.1
-
55
-
-
33845914783
-
2-Year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: A randomized controlled trial
-
Smith I, Procter M, Gelber RD, et al. 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomized controlled trial. Lancet 2007; 369: 29-36.
-
(2007)
Lancet
, vol.369
, pp. 29-36
-
-
Smith, I.1
Procter, M.2
Gelber, R.D.3
-
56
-
-
23944476155
-
Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas
-
Burris HA 3rd, Hurwitz HI, Dees EC, et al. Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas. J Clin Oncol 2005; 23: 5305-13.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5305-5313
-
-
Burris III, H.A.1
Hurwitz, H.I.2
Dees, E.C.3
-
57
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
DOI 10.1056/NEJMoa064320
-
Geyer CE, Forster J, Lindquist D, et al. Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med 2006; 355: 2733-2743 (Pubitemid 46021510)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.26
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
Chan, S.4
Romieu, C.G.5
Pienkowski, T.6
Jagiello-Gruszfeld, A.7
Crown, J.8
Chan, A.9
Kaufman, B.10
Skarlos, D.11
Campone, M.12
Davidson, N.13
Berger, M.14
Oliva, C.15
Rubin, S.D.16
Stein, S.17
Cameron, D.18
-
58
-
-
44949253343
-
Cardiac safety of lapatinib: Pooled analysis of 3689 patients enrolled in clinical trials
-
DOI 10.4065/83.6.679
-
Perez EA, Koehler M, Byrne J, et al. Cardiac safety of lapatinib: pooled analysis of 3689 patients enrolled in clinical trials. Mayo Clin Proc 2008; 83: 679-686 (Pubitemid 351810568)
-
(2008)
Mayo Clinic Proceedings
, vol.83
, Issue.6
, pp. 679-686
-
-
Perez, E.A.1
Koehler, M.2
Byrne, J.3
Preston, A.J.4
Rappold, E.5
Ewer, M.S.6
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