메뉴 건너뛰기




Volumn 49, Issue 1, 2009, Pages 59-73

Expression and function of phospholipase C in breast carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ISOENZYME; MESSENGER RNA; PHOSPHOLIPASE C DELTA; PLCD1 PROTEIN, HUMAN; PLCD3 PROTEIN, HUMAN; SMALL INTERFERING RNA;

EID: 66449087449     PISSN: 00652571     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.advenzreg.2009.01.009     Document Type: Article
Times cited : (20)

References (63)
  • 1
    • 33646806089 scopus 로고    scopus 로고
    • The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon
    • Ada-Nguema A.S., Xenias H., Hofman J.M., Wiggins C.H., Sheetz M.P., and Keely P.J. The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon. J Cell Sci 119 (2006) 1307-1319
    • (2006) J Cell Sci , vol.119 , pp. 1307-1319
    • Ada-Nguema, A.S.1    Xenias, H.2    Hofman, J.M.3    Wiggins, C.H.4    Sheetz, M.P.5    Keely, P.J.6
  • 2
    • 34548081943 scopus 로고    scopus 로고
    • Phospholipase C-{beta}2 promotes mitosis and migration of human breast cancer derived cells
    • Bertagnolo V., Benedusi M., Brugnoli F., Lanuti P., Marchisio M., Querzoli P., et al. Phospholipase C-{beta}2 promotes mitosis and migration of human breast cancer derived cells. Carcinogenesis 28 (2007) 1638-1645
    • (2007) Carcinogenesis , vol.28 , pp. 1638-1645
    • Bertagnolo, V.1    Benedusi, M.2    Brugnoli, F.3    Lanuti, P.4    Marchisio, M.5    Querzoli, P.6
  • 3
    • 33744735676 scopus 로고    scopus 로고
    • PLC-beta2 is highly expressed in breast cancer and is associated with a poor outcome: a study on tissue microarrays
    • Bertagnolo V., Benedusi M., Querzoli P., Pedriali M., Magri E., Brugnoli F., et al. PLC-beta2 is highly expressed in breast cancer and is associated with a poor outcome: a study on tissue microarrays. Int J Oncol 28 (2006) 863-872
    • (2006) Int J Oncol , vol.28 , pp. 863-872
    • Bertagnolo, V.1    Benedusi, M.2    Querzoli, P.3    Pedriali, M.4    Magri, E.5    Brugnoli, F.6
  • 4
    • 32444445745 scopus 로고    scopus 로고
    • Structural and mechanistic insights into ras association domains of phospholipase C epsilon
    • Bunney T.D., Harris R., Gandarillas N.L., Josephs M.B., Roe S.M., Sorli S.C., et al. Structural and mechanistic insights into ras association domains of phospholipase C epsilon. Mol Cell 21 (2006) 495-507
    • (2006) Mol Cell , vol.21 , pp. 495-507
    • Bunney, T.D.1    Harris, R.2    Gandarillas, N.L.3    Josephs, M.B.4    Roe, S.M.5    Sorli, S.C.6
  • 5
    • 33751315308 scopus 로고    scopus 로고
    • Phospholipase C epsilon: linking second messengers and small GTPases
    • Bunney T.D., and Katan M. Phospholipase C epsilon: linking second messengers and small GTPases. Trends Cell Biol 16 (2006) 640-648
    • (2006) Trends Cell Biol , vol.16 , pp. 640-648
    • Bunney, T.D.1    Katan, M.2
  • 6
    • 0028089832 scopus 로고
    • Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement
    • Chen P., Xie H., Sekar M.C., Gupta K., and Wells A. Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement. J Cell Biol 127 (1994) 847-857
    • (1994) J Cell Biol , vol.127 , pp. 847-857
    • Chen, P.1    Xie, H.2    Sekar, M.C.3    Gupta, K.4    Wells, A.5
  • 7
    • 33745251632 scopus 로고    scopus 로고
    • Phosphoinositide-specific phospholipase C (PI-PLC) beta1 and nuclear lipid-dependent signaling
    • Cocco L., Faenza I., Fiume R., Maria Billi A., Gilmour R.S., and Manzoli F.A. Phosphoinositide-specific phospholipase C (PI-PLC) beta1 and nuclear lipid-dependent signaling. Biochim Biophys Acta 1761 (2006) 509-521
    • (2006) Biochim Biophys Acta , vol.1761 , pp. 509-521
    • Cocco, L.1    Faenza, I.2    Fiume, R.3    Maria Billi, A.4    Gilmour, R.S.5    Manzoli, F.A.6
  • 8
    • 0345059766 scopus 로고    scopus 로고
    • Intravital imaging of cell movement in tumours
    • Condeelis J., and Segall J.E. Intravital imaging of cell movement in tumours. Nat Rev Cancer 3 (2003) 921-930
    • (2003) Nat Rev Cancer , vol.3 , pp. 921-930
    • Condeelis, J.1    Segall, J.E.2
  • 10
    • 0036832606 scopus 로고    scopus 로고
    • Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via EGFR
    • Dittmar T., Husemann A., Schewe Y., Nofer J.R., Niggemann B., Zanker K.S., et al. Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via EGFR. Faseb J 16 (2002) 1823-1825
    • (2002) Faseb J , vol.16 , pp. 1823-1825
    • Dittmar, T.1    Husemann, A.2    Schewe, Y.3    Nofer, J.R.4    Niggemann, B.5    Zanker, K.S.6
  • 11
    • 0037053293 scopus 로고    scopus 로고
    • Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B
    • Evellin S., Nolte J., Tysack K., vom Dorp F., Thiel M., Weernink P.A., et al. Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B. J Biol Chem 277 (2002) 16805-16813
    • (2002) J Biol Chem , vol.277 , pp. 16805-16813
    • Evellin, S.1    Nolte, J.2    Tysack, K.3    vom Dorp, F.4    Thiel, M.5    Weernink, P.A.6
  • 12
    • 0033573849 scopus 로고    scopus 로고
    • Alpha 1B-adrenoceptor interacts with multiple sites of transglutaminase II: characteristics of the interaction in binding and activation
    • Feng J.F., Gray C.D., and Im M.J. Alpha 1B-adrenoceptor interacts with multiple sites of transglutaminase II: characteristics of the interaction in binding and activation. Biochemistry 38 (1999) 2224-2232
    • (1999) Biochemistry , vol.38 , pp. 2224-2232
    • Feng, J.F.1    Gray, C.D.2    Im, M.J.3
  • 13
    • 0029666275 scopus 로고    scopus 로고
    • Evidence that phospholipase delta1 is the effector in the Gh (transglutaminase II)-mediated signaling
    • Feng J.F., Rhee S.G., and Im M.J. Evidence that phospholipase delta1 is the effector in the Gh (transglutaminase II)-mediated signaling. J Biol Chem 271 (1996) 16451-16454
    • (1996) J Biol Chem , vol.271 , pp. 16451-16454
    • Feng, J.F.1    Rhee, S.G.2    Im, M.J.3
  • 15
    • 36349033101 scopus 로고    scopus 로고
    • Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma
    • Fu L., Qin Y.R., Xie D., Hu L., Kwong D.L., Srivastava G., et al. Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma. Cancer Res 67 (2007) 10720-10726
    • (2007) Cancer Res , vol.67 , pp. 10720-10726
    • Fu, L.1    Qin, Y.R.2    Xie, D.3    Hu, L.4    Kwong, D.L.5    Srivastava, G.6
  • 16
    • 12544250874 scopus 로고    scopus 로고
    • Phospholipase C{beta}2 binds to and inhibits phospholipase C{delta}1
    • Guo Y., Rebecchi M., and Scarlata S. Phospholipase C{beta}2 binds to and inhibits phospholipase C{delta}1. J Biol Chem 280 (2005) 1438-1447
    • (2005) J Biol Chem , vol.280 , pp. 1438-1447
    • Guo, Y.1    Rebecchi, M.2    Scarlata, S.3
  • 17
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 18
    • 33144456377 scopus 로고    scopus 로고
    • Regulation of phospholipase C isozymes by ras superfamily GTPases
    • Harden T.K., and Sondek J. Regulation of phospholipase C isozymes by ras superfamily GTPases. Annu Rev Pharmacol Toxicol 46 (2006) 355-379
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 355-379
    • Harden, T.K.1    Sondek, J.2
  • 19
    • 0032572105 scopus 로고    scopus 로고
    • Regulation of phospholipase C-delta by GTP-binding proteins-rhoA as an inhibitory modulator
    • Hodson E.A., Ashley C.C., Hughes A.D., and Lymn J.S. Regulation of phospholipase C-delta by GTP-binding proteins-rhoA as an inhibitory modulator. Biochim Biophys Acta 1403 (1998) 97-101
    • (1998) Biochim Biophys Acta , vol.1403 , pp. 97-101
    • Hodson, E.A.1    Ashley, C.C.2    Hughes, A.D.3    Lymn, J.S.4
  • 20
    • 0028025472 scopus 로고
    • Enhanced phosphoinositide metabolism in colorectal carcinoma cells derived from familial adenomatous polyposis patients
    • Homma M.K., Homma Y., Namba M., and Yuasa Y. Enhanced phosphoinositide metabolism in colorectal carcinoma cells derived from familial adenomatous polyposis patients. J Cell Biochem 55 (1994) 477-485
    • (1994) J Cell Biochem , vol.55 , pp. 477-485
    • Homma, M.K.1    Homma, Y.2    Namba, M.3    Yuasa, Y.4
  • 21
    • 0028853289 scopus 로고
    • A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities
    • Homma Y., and Emori Y. A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities. EMBO J 14 (1995) 286-291
    • (1995) EMBO J , vol.14 , pp. 286-291
    • Homma, Y.1    Emori, Y.2
  • 22
    • 22144495354 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel phospholipase C, PLC-eta
    • Hwang J.I., Oh Y.S., Shin K.J., Kim H., Ryu S.H., and Suh P.G. Molecular cloning and characterization of a novel phospholipase C, PLC-eta. Biochem J 389 (2005) 181-186
    • (2005) Biochem J , vol.389 , pp. 181-186
    • Hwang, J.I.1    Oh, Y.S.2    Shin, K.J.3    Kim, H.4    Ryu, S.H.5    Suh, P.G.6
  • 24
    • 0032476733 scopus 로고    scopus 로고
    • Stimulation of phospholipase C-beta2 by the Rho GTPases Cdc42Hs and Rac1
    • Illenberger D., Schwald F., Pimmer D., Binder W., Maier G., Dietrich A., et al. Stimulation of phospholipase C-beta2 by the Rho GTPases Cdc42Hs and Rac1. EMBO J 17 (1998) 6241-6249
    • (1998) EMBO J , vol.17 , pp. 6241-6249
    • Illenberger, D.1    Schwald, F.2    Pimmer, D.3    Binder, W.4    Maier, G.5    Dietrich, A.6
  • 25
    • 0037474209 scopus 로고    scopus 로고
    • Specificity and structural requirements of phospholipase C-beta stimulation by Rho GTPases versus G protein beta gamma dimers
    • Illenberger D., Walliser C., Nurnberg B., Diaz Lorente M., and Gierschik P. Specificity and structural requirements of phospholipase C-beta stimulation by Rho GTPases versus G protein beta gamma dimers. J Biol Chem 278 (2003) 3006-3014
    • (2003) J Biol Chem , vol.278 , pp. 3006-3014
    • Illenberger, D.1    Walliser, C.2    Nurnberg, B.3    Diaz Lorente, M.4    Gierschik, P.5
  • 27
    • 0030967648 scopus 로고    scopus 로고
    • Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development
    • [see comments]
    • Ji Q.S., Winnier G.E., Niswender K.D., Horstman D., Wisdom R., Magnuson M.A., et al. Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development. [see comments]. Proc Natl Acad Sci USA 94 (1997) 2999-3003
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2999-3003
    • Ji, Q.S.1    Winnier, G.E.2    Niswender, K.D.3    Horstman, D.4    Wisdom, R.5    Magnuson, M.A.6
  • 29
    • 0842308379 scopus 로고    scopus 로고
    • Antitumour effects of PLC-gamma1-(SH2)2-TAT fusion proteins on EGFR/c-erbB-2-positive breast cancer cells
    • Katterle Y., Brandt B.H., Dowdy S.F., Niggemann B., Zanker K.S., and Dittmar T. Antitumour effects of PLC-gamma1-(SH2)2-TAT fusion proteins on EGFR/c-erbB-2-positive breast cancer cells. Br J Cancer 90 (2004) 230-235
    • (2004) Br J Cancer , vol.90 , pp. 230-235
    • Katterle, Y.1    Brandt, B.H.2    Dowdy, S.F.3    Niggemann, B.4    Zanker, K.S.5    Dittmar, T.6
  • 30
    • 1542344841 scopus 로고    scopus 로고
    • Hormonal regulation of phospholipase Cepsilon through distinct and overlapping pathways involving G12 and Ras family G-proteins
    • Kelley G.G., Reks S.E., and Smrcka A.V. Hormonal regulation of phospholipase Cepsilon through distinct and overlapping pathways involving G12 and Ras family G-proteins. Biochem J 378 (2004) 129-139
    • (2004) Biochem J , vol.378 , pp. 129-139
    • Kelley, G.G.1    Reks, S.E.2    Smrcka, A.V.3
  • 31
    • 42149177825 scopus 로고    scopus 로고
    • The regulation of cell motility and chemotaxis by phospholipid signaling
    • Kolsch V., Charest P.G., and Firtel R.A. The regulation of cell motility and chemotaxis by phospholipid signaling. J Cell Sci 121 (2008) 551-559
    • (2008) J Cell Sci , vol.121 , pp. 551-559
    • Kolsch, V.1    Charest, P.G.2    Firtel, R.A.3
  • 32
    • 2942627762 scopus 로고    scopus 로고
    • Phospholipase C delta-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells
    • Leung D.W., Tompkins C., Brewer J., Ball A., Coon M., Morris V., et al. Phospholipase C delta-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells. Mol Cancer 3 (2004) 15
    • (2004) Mol Cancer , vol.3 , pp. 15
    • Leung, D.W.1    Tompkins, C.2    Brewer, J.3    Ball, A.4    Coon, M.5    Morris, V.6
  • 33
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumour-host interface
    • Liotta L.A., and Kohn E.C. The microenvironment of the tumour-host interface. Nature 411 (2001) 375-379
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 34
    • 3042531037 scopus 로고    scopus 로고
    • Ghalpha/tissue transglutaminase 2: an emerging G protein in signal transduction
    • Mhaouty-Kodja S. Ghalpha/tissue transglutaminase 2: an emerging G protein in signal transduction. Biol Cell 96 (2004) 363-367
    • (2004) Biol Cell , vol.96 , pp. 363-367
    • Mhaouty-Kodja, S.1
  • 35
    • 33750948427 scopus 로고    scopus 로고
    • Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis
    • Mouneimne G., DesMarais V., Sidani M., Scemes E., Wang W., Song X., et al. Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis. Curr Biol 16 (2006) 2193-2205
    • (2006) Curr Biol , vol.16 , pp. 2193-2205
    • Mouneimne, G.1    DesMarais, V.2    Sidani, M.3    Scemes, E.4    Wang, W.5    Song, X.6
  • 36
    • 4444296491 scopus 로고    scopus 로고
    • Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation
    • Mouneimne G., Soon L., DesMarais V., Sidani M., Song X., Yip S.C., et al. Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation. J Cell Biol 166 (2004) 697-708
    • (2004) J Cell Biol , vol.166 , pp. 697-708
    • Mouneimne, G.1    Soon, L.2    DesMarais, V.3    Sidani, M.4    Song, X.5    Yip, S.C.6
  • 37
    • 0037938632 scopus 로고    scopus 로고
    • Phospholipase Cdelta1 is required for skin stem cell lineage commitment
    • Nakamura Y., Fukami K., Yu H., Takenaka K., Kataoka Y., Shirakata Y., et al. Phospholipase Cdelta1 is required for skin stem cell lineage commitment. EMBO J 22 (2003) 2981-2991
    • (2003) EMBO J , vol.22 , pp. 2981-2991
    • Nakamura, Y.1    Fukami, K.2    Yu, H.3    Takenaka, K.4    Kataoka, Y.5    Shirakata, Y.6
  • 38
    • 28544450506 scopus 로고    scopus 로고
    • Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development
    • Nakamura Y., Hamada Y., Fujiwara T., Enomoto H., Hiroe T., Tanaka S., et al. Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development. Mol Cell Biol 25 (2005) 10979-10988
    • (2005) Mol Cell Biol , vol.25 , pp. 10979-10988
    • Nakamura, Y.1    Hamada, Y.2    Fujiwara, T.3    Enomoto, H.4    Hiroe, T.5    Tanaka, S.6
  • 39
    • 40449124691 scopus 로고    scopus 로고
    • Phospholipase C-delta1 is an essential molecule downstream of Foxn1, the gene responsible for the nude mutation, in normal hair development
    • Nakamura Y., Ichinohe M., Hirata M., Matsuura H., Fujiwara T., Igarashi T., et al. Phospholipase C-delta1 is an essential molecule downstream of Foxn1, the gene responsible for the nude mutation, in normal hair development. Faseb J 22 (2008) 841-849
    • (2008) Faseb J , vol.22 , pp. 841-849
    • Nakamura, Y.1    Ichinohe, M.2    Hirata, M.3    Matsuura, H.4    Fujiwara, T.5    Igarashi, T.6
  • 40
    • 34250783088 scopus 로고    scopus 로고
    • Integrative analysis of transcriptomic and proteomic data: challenges, solutions and applications
    • Nie L., Wu G., Culley D.E., Scholten J.C., and Zhang W. Integrative analysis of transcriptomic and proteomic data: challenges, solutions and applications. Crit Rev Biotechnol 27 (2007) 63-75
    • (2007) Crit Rev Biotechnol , vol.27 , pp. 63-75
    • Nie, L.1    Wu, G.2    Culley, D.E.3    Scholten, J.C.4    Zhang, W.5
  • 41
    • 0031810796 scopus 로고    scopus 로고
    • Expression of phospholipase C-gamma 1 and its transcriptional regulators in breast cancer tissues
    • Noh D.Y., Kang H.S., Kim Y.C., Youn Y.K., Oh S.K., Choe K.J., et al. Expression of phospholipase C-gamma 1 and its transcriptional regulators in breast cancer tissues. Anticancer Res 18 (1998) 2643-2648
    • (1998) Anticancer Res , vol.18 , pp. 2643-2648
    • Noh, D.Y.1    Kang, H.S.2    Kim, Y.C.3    Youn, Y.K.4    Oh, S.K.5    Choe, K.J.6
  • 42
    • 0028985929 scopus 로고
    • Expression of phospholipases gamma 1, beta 1, and delta 1 in primary human colon carcinomas and colon carcinoma cell lines
    • Nomoto K., Tomita N., Miyake M., Xhu D.B., LoGerfo P.R., and Weinstein I.B. Expression of phospholipases gamma 1, beta 1, and delta 1 in primary human colon carcinomas and colon carcinoma cell lines. Mol Carcinog 12 (1995) 146-152
    • (1995) Mol Carcinog , vol.12 , pp. 146-152
    • Nomoto, K.1    Tomita, N.2    Miyake, M.3    Xhu, D.B.4    LoGerfo, P.R.5    Weinstein, I.B.6
  • 43
    • 2342627142 scopus 로고    scopus 로고
    • Isozymes delta of phosphoinositide-specific phospholipase C and their role in signal transduction in the cell
    • Ochocka A.M., and Pawelczyk T. Isozymes delta of phosphoinositide-specific phospholipase C and their role in signal transduction in the cell. Acta Biochim Pol 50 (2003) 1097-1110
    • (2003) Acta Biochim Pol , vol.50 , pp. 1097-1110
    • Ochocka, A.M.1    Pawelczyk, T.2
  • 44
    • 0037136701 scopus 로고    scopus 로고
    • The mechanism involved in the regulation of phospholipase Cgamma1 activity in cell migration
    • Piccolo E., Innominato P.F., Mariggio M.A., Maffucci T., Iacobelli S., and Falasca M. The mechanism involved in the regulation of phospholipase Cgamma1 activity in cell migration. Oncogene 21 (2002) 6520-6529
    • (2002) Oncogene , vol.21 , pp. 6520-6529
    • Piccolo, E.1    Innominato, P.F.2    Mariggio, M.A.3    Maffucci, T.4    Iacobelli, S.5    Falasca, M.6
  • 47
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy S., Ross K.N., Lander E.S., and Golub T.R. A molecular signature of metastasis in primary solid tumors. Nat Genet 33 (2003) 49-54
    • (2003) Nat Genet , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3    Golub, T.R.4
  • 48
    • 0033779101 scopus 로고    scopus 로고
    • Structure, function, and control of phosphoinositide-specific phospholipase C
    • Rebecchi M.J., and Pentyala S.N. Structure, function, and control of phosphoinositide-specific phospholipase C. Physiol Rev 80 (2000) 1291-1335
    • (2000) Physiol Rev , vol.80 , pp. 1291-1335
    • Rebecchi, M.J.1    Pentyala, S.N.2
  • 49
    • 37249000008 scopus 로고    scopus 로고
    • EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells
    • van Rheenen J., Song X., van Roosmalen W., Cammer M., Chen X., Desmarais V., et al. EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells. J Cell Biol 179 (2007) 1247-1259
    • (2007) J Cell Biol , vol.179 , pp. 1247-1259
    • van Rheenen, J.1    Song, X.2    van Roosmalen, W.3    Cammer, M.4    Chen, X.5    Desmarais, V.6
  • 50
    • 0035735452 scopus 로고    scopus 로고
    • A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase
    • Schmidt M., Evellin S., Weernink P.A., von Dorp F., Rehmann H., Lomasney J.W., et al. A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase. Nat Cell Biol 3 (2001) 1020-1024
    • (2001) Nat Cell Biol , vol.3 , pp. 1020-1024
    • Schmidt, M.1    Evellin, S.2    Weernink, P.A.3    von Dorp, F.4    Rehmann, H.5    Lomasney, J.W.6
  • 51
    • 0023792919 scopus 로고
    • Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines
    • Scudiero D.A., Shoemaker R.H., Paull K.D., Monks A., Tierney S., Nofziger T.H., et al. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res 48 (1988) 4827-4833
    • (1988) Cancer Res , vol.48 , pp. 4827-4833
    • Scudiero, D.A.1    Shoemaker, R.H.2    Paull, K.D.3    Monks, A.4    Tierney, S.5    Nofziger, T.H.6
  • 52
    • 20444477143 scopus 로고    scopus 로고
    • Regulation of phospholipase C-delta1 through direct interactions with the small GTPase Ral and calmodulin
    • Sidhu R.S., Clough R.R., and Bhullar R.P. Regulation of phospholipase C-delta1 through direct interactions with the small GTPase Ral and calmodulin. J Biol Chem 280 (2005) 21933-21941
    • (2005) J Biol Chem , vol.280 , pp. 21933-21941
    • Sidhu, R.S.1    Clough, R.R.2    Bhullar, R.P.3
  • 53
    • 0038756655 scopus 로고    scopus 로고
    • The pleckstrin homology domain of phospholipase C-beta2 as an effector site for Rac
    • Snyder J.T., Singer A.U., Wing M.R., Harden T.K., and Sondek J. The pleckstrin homology domain of phospholipase C-beta2 as an effector site for Rac. J Biol Chem 278 (2003) 21099-21104
    • (2003) J Biol Chem , vol.278 , pp. 21099-21104
    • Snyder, J.T.1    Singer, A.U.2    Wing, M.R.3    Harden, T.K.4    Sondek, J.5
  • 54
    • 0035951771 scopus 로고    scopus 로고
    • Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras
    • Song C., Hu C.D., Masago M., Kariyai K., Yamawaki-Kataoka Y., Shibatohge M., et al. Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras. J Biol Chem 276 (2001) 2752-2757
    • (2001) J Biol Chem , vol.276 , pp. 2752-2757
    • Song, C.1    Hu, C.D.2    Masago, M.3    Kariyai, K.4    Yamawaki-Kataoka, Y.5    Shibatohge, M.6
  • 55
    • 0037153376 scopus 로고    scopus 로고
    • Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase C epsilon
    • Song C., Satoh T., Edamatsu H., Wu D., Tadano M., Gao X., et al. Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase C epsilon. Oncogene 21 (2002) 8105-8113
    • (2002) Oncogene , vol.21 , pp. 8105-8113
    • Song, C.1    Satoh, T.2    Edamatsu, H.3    Wu, D.4    Tadano, M.5    Gao, X.6
  • 56
    • 46249125729 scopus 로고    scopus 로고
    • Phospholipase C-δ1 is linked to proliferation, DNA synthesis and cyclin E expression
    • Stallings J., Zhang Y., Naravez F., and Rebecchi M.J. Phospholipase C-δ1 is linked to proliferation, DNA synthesis and cyclin E expression. J Biol Chem 283 (2008) 13992-14001
    • (2008) J Biol Chem , vol.283 , pp. 13992-14001
    • Stallings, J.1    Zhang, Y.2    Naravez, F.3    Rebecchi, M.J.4
  • 57
    • 20444497331 scopus 로고    scopus 로고
    • Nuclear translocation of phospholipase C-delta1 is linked to the cell cycle and nuclear phosphatidylinositol 4,5-bisphosphate
    • Stallings J.D., Tall E.G., Pentyala S., and Rebecchi M.J. Nuclear translocation of phospholipase C-delta1 is linked to the cell cycle and nuclear phosphatidylinositol 4,5-bisphosphate. J Biol Chem 280 (2005) 22060-22069
    • (2005) J Biol Chem , vol.280 , pp. 22060-22069
    • Stallings, J.D.1    Tall, E.G.2    Pentyala, S.3    Rebecchi, M.J.4
  • 58
    • 46249091922 scopus 로고    scopus 로고
    • Multiple roles of phosphoinositide-specific phospholipase C isozymes
    • Suh P.G., Park J.I., Manzoli L., Cocco L., Peak J.C., Katan M., et al. Multiple roles of phosphoinositide-specific phospholipase C isozymes. BMB Rep 41 (2008) 415-434
    • (2008) BMB Rep , vol.41 , pp. 415-434
    • Suh, P.G.1    Park, J.I.2    Manzoli, L.3    Cocco, L.4    Peak, J.C.5    Katan, M.6
  • 59
    • 34548268026 scopus 로고    scopus 로고
    • Modelling breast cancer: one size does not fit all
    • Vargo-Gogola T., and Rosen J.M. Modelling breast cancer: one size does not fit all. Nat Rev Cancer 7 (2007) 659-672
    • (2007) Nat Rev Cancer , vol.7 , pp. 659-672
    • Vargo-Gogola, T.1    Rosen, J.M.2
  • 60
    • 34249281332 scopus 로고    scopus 로고
    • The cofilin pathway in breast cancer invasion and metastasis
    • Wang W., Eddy R., and Condeelis J. The cofilin pathway in breast cancer invasion and metastasis. Nat Rev Cancer 7 (2007) 429-440
    • (2007) Nat Rev Cancer , vol.7 , pp. 429-440
    • Wang, W.1    Eddy, R.2    Condeelis, J.3
  • 61
    • 33646386905 scopus 로고    scopus 로고
    • The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
    • Wang W., Mouneimne G., Sidani M., Wyckoff J., Chen X., Makris A., et al. The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors. J Cell Biol 173 (2006) 395-404
    • (2006) J Cell Biol , vol.173 , pp. 395-404
    • Wang, W.1    Mouneimne, G.2    Sidani, M.3    Wyckoff, J.4    Chen, X.5    Makris, A.6
  • 62
    • 28444483081 scopus 로고    scopus 로고
    • Down-regulation of increased signal transduction capacity in human cancer cells
    • Weber G. Down-regulation of increased signal transduction capacity in human cancer cells. Adv Enzyme Regul 45 (2005) 37-51
    • (2005) Adv Enzyme Regul , vol.45 , pp. 37-51
    • Weber, G.1
  • 63
    • 0028582214 scopus 로고
    • Reduced expression of phospholipase C-delta, a signal-transducing enzyme, in rat colon neoplasms induced by methylazoxymethanol acetate
    • Yoshimi N., Wang A., Makita H., Suzui M., Mori H., Okano Y., et al. Reduced expression of phospholipase C-delta, a signal-transducing enzyme, in rat colon neoplasms induced by methylazoxymethanol acetate. Mol Carcinog 11 (1994) 192-196
    • (1994) Mol Carcinog , vol.11 , pp. 192-196
    • Yoshimi, N.1    Wang, A.2    Makita, H.3    Suzui, M.4    Mori, H.5    Okano, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.