-
1
-
-
43549095495
-
A novel antineoplastic agent with low susceptibility to multiple tumor resistance mechanisms
-
Vahdat L. Ixabepilone: A novel antineoplastic agent with low susceptibility to multiple tumor resistance mechanisms. The Oncologist 2008;13:214-221.
-
(2008)
The Oncologist
, vol.13
, pp. 214-221
-
-
Ixabepilone, V.L.1
-
2
-
-
3042701597
-
Epothilones: Mechanism of action and biologic activity
-
Goodin S, Kane MP, Rubin EH. Epothilones: Mechanism of action and biologic activity. J Clin Oncol 2004;22:2015-2025.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2015-2025
-
-
Goodin, S.1
Kane, M.P.2
Rubin, E.H.3
-
3
-
-
0037177229
-
Epothilone and paclitaxel: Unexpected differences in promoting the assembly and stabilization of yeast microtubules
-
DOI 10.1021/bi0121611
-
Bode CJ, Gupta ML Jr., Reiff EA et al. Epothilone and paclitaxel: Unexpected differences in promoting the assembly and stabilization of yeast microtubules. Biochemistry 2002;41:3870-3874. (Pubitemid 34251025)
-
(2002)
Biochemistry
, vol.41
, Issue.12
, pp. 3870-3874
-
-
Bode, C.J.1
Gupta Jr., M.L.2
Reiff, E.A.3
Suprenant, K.A.4
Georg, G.I.5
Himes, R.H.6
-
4
-
-
0034895987
-
BMS-247550: A novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy
-
Lee FYF, Borzilleri R, Fairchild CR et al. BMS-247550: A novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy. Clin Cancer Res 2001;7:1429-1437. (Pubitemid 32708699)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.5
, pp. 1429-1437
-
-
Lee, F.Y.F.1
Borzilleri, R.2
Fairchild, C.R.3
Kim, S.-H.4
Long, B.H.5
Reventos-Suarez, C.6
Vite, G.D.7
Rose, W.C.8
Kramer, R.A.9
-
5
-
-
57149135866
-
Preclinical efficacy spectrum and pharmacokinetics of ixabepilone
-
Lee FYF, Smykla R, Johnston K et al. Preclinical efficacy spectrum and pharmacokinetics of ixabepilone. Cancer Chemother Pharmacol 2009;63:201-212.
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 201-212
-
-
Lee, F.Y.F.1
Smykla, R.2
Johnston, K.3
-
6
-
-
28944441595
-
Development of novel chemotherapeutic agents to evade the mechanisms of multidrug resistance (MDR)
-
DOI 10.1053/j.seminoncol.2005.09.013, PII S0093775405003933
-
Lee JJ, Swain SM. Development of novel chemotherapeutic agents to evade the mechanisms of multidrug resistance (MDR). Semin Oncol 2005;32(suppl 7):S22-S26. (Pubitemid 41785443)
-
(2005)
Seminars in Oncology
, vol.32
, Issue.SUPPL. 7
-
-
Lee, J.J.1
Swain, S.M.2
-
7
-
-
38449121276
-
Roles of multidrug resistance genes in breast cancer chemoresistance
-
Kuo MT. Roles of multidrug resistance genes in breast cancer chemoresistance. Adv Exp Med Biol 2007;608:23-30.
-
(2007)
Adv Exp Med Biol
, vol.608
, pp. 23-30
-
-
Kuo, M.T.1
-
8
-
-
34548157209
-
Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine
-
DOI 10.1200/JCO.2006.09.3849
-
Perez EA, Lerzo G, Pivot X et al. Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine. J Clin Oncol 2007;25:3407-3414. (Pubitemid 47310876)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.23
, pp. 3407-3414
-
-
Perez, E.A.1
Lerzo, G.2
Pivot, X.3
Thomas, E.4
Vahdat, L.5
Bosserman, L.6
Viens, P.7
Cai, C.8
Mullaney, B.9
Peck, R.10
Hortobagyi, G.N.11
-
9
-
-
36849071808
-
Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment
-
DOI 10.1200/JCO.2007.12.6557
-
Thomas ES, Gomez HL, Li RK et al. Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment. J Clin Oncol 2007; 2007;25:5210-5217. (Pubitemid 350232252)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.33
, pp. 5210-5217
-
-
Thomas, E.S.1
Gomez, H.L.2
Li, R.K.3
Chung, H.-C.4
Fein, L.E.5
Chan, V.F.6
Jassem, J.7
Pivot, X.B.8
Klimovsky, J.V.9
De Mendoza, F.H.10
Xu, B.11
Campone, M.12
Lerzo, G.L.13
Peck, R.A.14
Mukhopadhyay, P.15
Vahdat, L.T.16
Roche, H.H.17
-
10
-
-
34548187738
-
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in patients with taxane-resistant metastatic breast cancer
-
DOI 10.1200/JCO.2006.08.9102
-
Thomas E, Tabernero J, Fornier M et al. Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in patients with taxane-resistant metastatic breast cancer. J Clin Oncol 2007;25:3399-3406. (Pubitemid 47310875)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.23
, pp. 3399-3406
-
-
Thomas, E.1
Tabernero, J.2
Fornier, M.3
Conte, P.4
Fumoleau, P.5
Lluch, A.6
Vahdat, L.T.7
Bunnell, C.A.8
Burris, H.A.9
Viens, P.10
Baselga, J.11
Rivera, E.12
Guarneri, V.13
Poulart, V.14
Klimovsky, J.15
Lebwohl, D.16
Martin, M.17
-
11
-
-
21044441003
-
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in metastatic and locally advanced breast cancer
-
DOI 10.1200/JCO.2005.10.024
-
Low JA, Wedam SB, Lee JJ et al. Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in metastatic and locally advanced breast cancer. J Clin Oncol 2005;23:2726-2734. (Pubitemid 46179462)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.12
, pp. 2726-2734
-
-
Low, J.A.1
Wedam, S.B.2
Lee, J.J.3
Berman, A.W.4
Brufsky, A.5
Yang, S.X.6
Poruchynsky, M.S.7
Steinberg, S.M.8
Mannan, N.9
Fojo, T.10
Swain, S.M.11
-
12
-
-
34548179878
-
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy
-
DOI 10.1200/JCO.2006.09.7535
-
Roché H, Yelle L, Cognetti F et al. Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy. J Clin Oncol 2007;25:3415-3420. (Pubitemid 47310877)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.23
, pp. 3415-3420
-
-
Roche, H.1
Yelle, L.2
Cognetti, F.3
Mauriac, L.4
Bunnell, C.5
Sparano, J.6
Kerbrat, P.7
Delord, J.-P.8
Vahdat, L.9
Peck, R.10
Lebwohl, D.11
Ezzeddine, R.12
Cure, H.13
-
13
-
-
34548169630
-
Phase II trial of ixabepilone, an epothilone B analog, in patients with metastatic breast cancer previously untreated with taxanes
-
DOI 10.1200/JCO.2006.10.0784
-
Denduluri N, Low JA, Lee JJ et al. Phase II trial of ixabepilone, an epothilone B analog, in patients with metastatic breast cancer previously untreated with taxanes. J Clin Oncol 2007;25:3421-3427. (Pubitemid 47310878)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.23
, pp. 3421-3427
-
-
Denduluri, N.1
Low, J.A.2
Lee, J.J.3
Berman, A.W.4
Walshe, J.M.5
Vatas, U.6
Chow, C.K.7
Steinberg, S.M.8
Yang, S.X.9
Swain, S.M.10
-
14
-
-
34247161458
-
Predicting response to ixabepilone: Genomics study in patients receiving single agent ixabepilone as neoadjuvant treatment for breast cancer (BC)
-
Baselga J, Gianni L, Llombart A et al. Predicting response to ixabepilone: Genomics study in patients receiving single agent ixabepilone as neoadjuvant treatment for breast cancer (BC). Breast Cancer Res Treat 2005;94(suppl 1):S31.
-
(2005)
Breast Cancer Res Treat
, vol.94
, Issue.SUPPL. 1
-
-
Baselga, J.1
Gianni, L.2
Llombart, A.3
-
15
-
-
36849056385
-
Preclinical efficacy evaluation of ixabepilone (BMS-247550) in combination with cetuximab or capecitabine in human colon and lung carcinoma xenografts
-
Lee FYF, Camuso A, Castenada C et al. Preclinical efficacy evaluation of ixabepilone (BMS-247550) in combination with cetuximab or capecitabine in human colon and lung carcinoma xenografts. J Clin Oncol 2006;24:597s.
-
(2006)
J Clin Oncol
, vol.24
-
-
Lee, F.Y.F.1
Camuso, A.2
Castenada, C.3
-
16
-
-
67049161336
-
Analysis of overall survival (OS) among patients (pts) with metastatic breast cancer (MBC) receiving either ixabepilone (I) plus capecitabine (C) or C alone: Results from two randomized phase III trials
-
Abstract 186.
-
Hortobagyi GN, Perez E, Vrdoljak E et al. Analysis of overall survival (OS) among patients (pts) with metastatic breast cancer (MBC) receiving either ixabepilone (I) plus capecitabine (C) or C alone: Results from two randomized phase III trials. ASCO 2008 Breast Cancer Symposium Proceedings, Abstract 186.
-
ASCO 2008 Breast Cancer Symposium Proceedings
-
-
Hortobagyi, G.N.1
Perez, E.2
Vrdoljak, E.3
-
18
-
-
66349093048
-
Final results from a phase I trial of ixabepilone given every three weeks in patients with advanced malignancies and lymphoma
-
Aghajanian C, O'Connor OA, Cohen M, et al. Final results from a phase I trial of ixabepilone given every three weeks in patients with advanced malignancies and lymphoma. J Clin Oncol 2006;24(18 suppl):88s.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 SUPPL.
-
-
Aghajanian, C.1
O'Connor, O.A.2
Cohen, M.3
-
19
-
-
33745989223
-
2006 Update of recommendations for the use of white blood cell growth factors: An evidence-based clinical practice guideline
-
DOI 10.1200/JCO.2006.06.4451
-
Smith TJ, Khatcheressian J, Lyman GH et al. 2006 update of recommendations for the use of white blood cell growth factors: An evidence-based clinical practice guideline. J Clin Oncol 2006;24:3187-3205. (Pubitemid 46638957)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.19
, pp. 3187-3205
-
-
Smith, T.J.1
Khatcheressian, J.2
Lyman, G.H.3
Ozer, H.4
Armitage, J.O.5
Balducci, L.6
Bennett, C.L.7
Cantor, S.B.8
Crawford, J.9
Cross, S.J.10
Demetri, G.11
Desch, C.E.12
Pizzo, P.A.13
Schiffer, C.A.14
Schwartzberg, L.15
Somerfield, M.R.16
Somlo, G.17
Wade, J.C.18
Wade, J.L.19
Winn, R.J.20
Wozniak, A.J.21
Wolff, A.C.22
more..
-
20
-
-
33645736326
-
Peripheral neuropathy induced by microtubule-stabilizing agents
-
DOI 10.1200/JCO.2005.04.0543
-
Lee JJ, Swain SM. Peripheral neuropathy induced by microtubule- stabilizing agents. J Clin Oncol 2006;24:1633-1642. (Pubitemid 46638788)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.10
, pp. 1633-1642
-
-
Lee, J.J.1
Swain, S.M.2
-
21
-
-
33845927528
-
Peripheral neuropathy: Pathogenic mechanisms and alternative therapies
-
Head KA. Peripheral neuropathy: Pathogenic mechanisms and alternative therapies. Altern Med Rev 2006;11:294-329. (Pubitemid 46037130)
-
(2006)
Alternative Medicine Review
, vol.11
, Issue.4
, pp. 294-329
-
-
Head, K.A.1
-
22
-
-
33847349337
-
Supportive care
-
DOI 10.1093/annonc/mdl449
-
Ludwig H, Zojer N. Supportive care. Ann Oncol 2007;18(suppl 1):i37-i44. (Pubitemid 46344639)
-
(2007)
Annals of Oncology
, vol.18
, Issue.SUPPL. 1
-
-
Ludwig, H.1
Zojer, N.2
-
23
-
-
34247340522
-
Primary care of the patient with cancer
-
Smith GF, Toonen TR. Primary care of the patient with cancer. Am Fam Physician 2007;75:1207-1214. (Pubitemid 46631818)
-
(2007)
American Family Physician
, vol.75
, Issue.8
, pp. 1207-1214
-
-
Smith, G.F.1
Toonen, T.R.2
-
24
-
-
4444353736
-
Management of hand-foot syndrome in patients treated with capecitabine (Xeloda)
-
DOI 10.1016/j.ejon.2004.06.007, PII S1462388904000547
-
Lassere Y, Hoff P. Management of hand-foot syndrome in patients treated with capecitabine (Xeloda). Eur J Oncol Nurs 2004;8(suppl 1):S31-S40. (Pubitemid 39194085)
-
(2004)
European Journal of Oncology Nursing
, vol.8
, Issue.SUPPL. 1
-
-
Lassere, Y.1
Hoff, P.2
-
26
-
-
52049120147
-
The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: A first in class epothilone B analogue in late-phase clinical development
-
Goel S, Cohen M, Cömezoglu SN et al. The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: A first in class epothilone B analogue in late-phase clinical development. Clin Cancer Res 2008;14:2701-2709.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2701-2709
-
-
Goel, S.1
Cohen, M.2
Cömezoglu, S.N.3
-
27
-
-
0037275524
-
Clinical pharmacokinetic profile of modafinil
-
DOI 10.2165/00003088-200342020-00002
-
Robertson P Jr, Hellriegel ET. Clinical pharmacokinetic profile of modafinil. Clin Pharmacokinet 2003;42:123-137. (Pubitemid 36188553)
-
(2003)
Clinical Pharmacokinetics
, vol.42
, Issue.2
, pp. 123-137
-
-
Robertson Jr., P.1
Hellriegel, E.T.2
-
28
-
-
0041621727
-
Neurotoxic complications of chemotherapy in patients with cancer: Clinical signs and optimal management
-
DOI 10.2165/00003495-200363150-00003
-
Verstappen CC, Helmans JJ, Hoekman K et al. Neurotoxic complications of chemotherapy in patients with cancer: Clinical signs and optimal management. Drugs 2003;63:1549-1563. (Pubitemid 36976138)
-
(2003)
Drugs
, vol.63
, Issue.15
, pp. 1549-1563
-
-
Verstappen, C.C.P.1
Heimans, J.J.2
Hoekman, K.3
Postma, T.J.4
|