Risks and side-effects of intrathecal morphine combined with spinal anaesthesia: A meta-analysis

Anaesthesia

Volumn 64, Issue 6, 2009, Pages 643-651

  Gehling, Markus ^a   Tryba, M ^a  

^a KLINIKUM KASSEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHINE; PLACEBO;

CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DATA BASE; HUMAN; META ANALYSIS; NAUSEA; POSTOPERATIVE ANALGESIA; PRURITUS; RATING SCALE; RESPIRATION DEPRESSION; REVIEW; RISK ASSESSMENT; SCORING SYSTEM; SPINAL ANESTHESIA; SYSTEMATIC REVIEW; URINE RETENTION; VOMITING;

ANALGESICS, OPIOID; ANESTHESIA, SPINAL; FEMALE; HUMANS; INJECTIONS, SPINAL; MALE; MORPHINE; PAIN, POSTOPERATIVE; POSTOPERATIVE COMPLICATIONS; POSTOPERATIVE NAUSEA AND VOMITING; PRURITUS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESPIRATORY INSUFFICIENCY; URINARY RETENTION;

EID: 66349098115     PISSN: 00032409     EISSN: 13652044     Source Type: Journal    
DOI: 10.1111/j.1365-2044.2008.05817.x     Document Type: Review

References (44)

1. Wang JK, Nauss LA, Thomas JE. Pain relief by intrathecally applied morphine in man. Anesthesiology 1979; 50: 149-151 (Pubitemid 9130744)
2. Kalso E. Effects of intrathecal morphine, injected with bupivacaine, on pain after orthopaedic surgery. British Journal of Anaesthesia 1983; 55: 415-422
3. Drakeford MK, Pettine KA, Brookshire L, Ebert F. Spinal narcotics for postoperative analgesia in total joint arthroplasty. A prospective study. Journal of Bone and Joint Surgery (American volume) 1991; 73: 424-428
4. Fogarty DJ, Milligan KR. Postoperative analgesia following total hip replacement: a comparison of intrathecal morphine and diamorphine. Journal of the Royal Society of Medicine 1995; 88: 70-72
5. Niemi L, Pitkanen MT, Tuominen M, Rosenberg PH. Comparison of intrathecal fentanyl infusion with intrathecal morphine infusion or bolus for postoperative pain relief after hip arthroplasty. Anesthesia & Analgesia 1993; 77: 126-130 (Pubitemid 23200970)
6. Slappendel R, Weber EW, Dirksen R, Gielen MJ, van Limbeek J. Optimization of the dose of intrathecal morphine in total hip surgery: a dose-finding study. Anesthesia & Analgesia 1999; 88: 822-826 (Pubitemid 29168854)
7. Paterson GMC, McQuay MHJ, Bullingham RES, Moore RA. Intradural morphine and diamorphine. Anaesthesia 1984; 39: 113-117
8. Abboud TK, Dror A, Mosaad P, et al. Mini-dose intrathecal morphine for the relief of post-cesarean section pain: safety, efficacy, and ventilatory responses to carbon dioxide. Anesthesia & Analgesia 1988; 67: 137-143 (Pubitemid 18061617)
9. Amanor-Boadu SD. Assessment of minidose intrathecal morphine for analgesia after hemorroidectomy. West African Journal of Medicine 1992; 11: 146-149
10. Campbell DC, Riben CM, Rooney ME, Crone LA, Yip RW. Intrathecal morphine for postpartum tubal ligation postoperative analgesia. Anesthesia & Analgesia 2001; 93: 1006-1011 (Pubitemid 32905995)
11. Cunningham AJ, McKenna JA, Skene DS. Single injection spinal anaesthesia with amethocaine and morphine for transurethral prostatectomy. British Journal of Anaesthesia 1983; 55: 423-427
12. Goyagi T, Nishikawa T. The addition of epinephrine enhances postoperative analgesia by intrathecal morphine. Anesthesia & Analgesia 1995; 81: 508-513
13. Gwirtz KH, Young JV, Byers RS, et al. The safety and efficacy of intrathecal opioid analgesia for acute post-operative pain. Anesthesia & Analgesia 1999; 88: 599-604.
14. McQuay HJ, Moore A. An Evidence Based Resource for Pain Relief. Oxford: Oxford University Press, 1998.
15. Abouleish E, Rawal N, Tobon-Randall B, et al. A clinical and laboratory study to compare the addition of 0.2 mg of morphine, 0.2 mg of epinephrine, or their combination to hyperbaric bupivacaine for spinal anesthesia in cesarean section. Anesthesia & Analgesia 1993; 77: 457-462 (Pubitemid 23263514)
16. Abouleish E, Rawal N, Fallon K, Hernandez D. Combined intrathecal morphine and bupivacaine for cesarean section. Anesthesia & Analgesia 1988; 67: 370-374 (Pubitemid 18098942)
17. Almeida RA, Lauretti GR, Mattos AL. Antinociceptive effect of low-dose intrathecal neostigmine combined with intrathecal morphine following gynecologic surgery. Anesthesiology 2003; 98: 495-498 (Pubitemid 36603342)
18. Chung CJ, Kim JS, Park HS, Chin YJ. The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia. Anesthesia & Analgesia 1998; 87: 341-346 (Pubitemid 28369089)
19. Cole PJ, Craske DA, Wheatley RG. Efficacy and respiratory effects of low-dose spinal morphine for postoperative analgesia following knee arthroplasty. British Journal of Anaesthesia 2000; 85: 233-237 (Pubitemid 30601612)
20. Eichler F, Decker T, Muller E, Kasper SM, Rutt J, Grond S. [Efficacy and safety of 0.1 mg of intrathecal morphine in arthroscopic knee joint surgery]. Der Schmerz 2004; 18: 515-519
21. Fogarty DJ, Carabine UA, Milligan KR. Comparison of the analgesic effects of intrathecal clonidine and intrathecal morphine after spinal anaesthesia in patients undergoing total hip replacement. British Journal of Anaesthesia 1993; 71: 661-664 (Pubitemid 23330993)
22. Gehling M, Tryba M, Lusebrink T, Zorn A. [Can the addition of clonidine improve the analgesic efficacy of low dose intrathecal morphine? A randomised double-blind trial]. Der Anaesthesist 2003; 52: 204-209
23. Grace D, Bunting H, Milligan KR, Fee JP. Postoperative analgesia after co-administration of clonidine and morphine by the intrathecal route in patients undergoing hip replacement. Anesthesia & Analgesia 1995; 80: 86-91.
24. Habib AS, Muir HA, White WD, Spahn TE, Olufolabi AJ, Breen TW. Intrathecal morphine for analgesia after post-partum bilateral tubal ligation. Anesthesia & Analgesia 2005; 100: 239-243 (Pubitemid 40013635)
25. Johnson A, Bengtsson M, Soderlind K, Lofstrom JB. Influence of intrathecal morphine and naloxone intervention on postoperative ventilatory regulation in elderly patients. Acta Anaesthesiologica Scandinavica 1992; 36: 436-444
26. Lanz E, Daublander M, Lipp M, Theiss D. 0.5 mg intrathecal morphine in spinal anesthesia. A double blind study on sensory block, postoperative analgesia and adverse effects. Regional Anesthesia 1984; 7: 79-85.
27. Mora C, Dupuis JL, Feiss P. [Spinal anesthesia and morphine analgesia in prostatic surgery]. Cahiers d' Anesthesiologie 1985; 33: 25-27
28. Murphy PM, Stack D, Kinirons B, Laffey JG. Optimizing the dose of intrathecal morphine in older patients undergoing hip arthroplasty. Anesthesia & Analgesia 2003; 97: 1709-1715 (Pubitemid 37475127)
29. Palmer CM, Emerson S, Volgoropolous D, Alves D. Dose-response relationship of intrathecal morphine for postcesarean analgesia. Anesthesiology 1999; 90: 437-444 (Pubitemid 29071512)
30. Rathmell JP, Pino CA, Taylor R, Patrin T, Viani BA. Intrathecal morphine for postoperative analgesia: a randomized, controlled, dose-ranging study after hip and knee arthroplasty. Anesthesia & Analgesia 2003; 97: 1452-1457 (Pubitemid 37310146)
31. Sakai T, Use T, Shimamoto H, Fukano T, Sumikawa K. Mini-dose (0.05 mg) intrathecal morphine provides effective analgesia after transurethral resection of the prostate. Canadian Journal of Anesthesia 2003; 50: 1027-1030 (Pubitemid 38139566)
32. Schaer H, Baasch K, Prochacka K. [Intrathecal morphine for postoperative pain]. Der Anaesthesist 1992; 41: 689-693
33. Sites BD, Beach M, Biggs R, et al. Intrathecal clonidine added to a bupivacaine-morphine spinal anesthetic improves postoperative analgesia for total knee arthroplasty. Anesthesia & Analgesia 2003; 96: 1083-1088 (Pubitemid 36359048)
34. Tan PH, Chia YY, Lo Y, Liu K, Yang LC, Lee TH. Intrathecal bupivacaine with morphine or neostigmine for postoperative analgesia after total knee replacement surgery. Canadian Journal of Anesthesia 2001; 48: 551-556 (Pubitemid 32684871)
35. Dahl JA, Jeppesen IS, Jorgensen H, Wetterslev J, Moiniche S. Intraoperative and postoperative analgesic efficacy and adverse effects on intrathecal opioids in patientes undergoing cesarean section with spinal anesthesia. Anesthesiology 1999; 91: 1919-1927
36. Tobias JD. A review of intrathecal and epidural analgesia after spinal surgery in children. Anesthesia & Analgesia 2004; 98: 956-965 (Pubitemid 38405402)
37. Yazigi A, Chalhoub V, Madi-Jebara S, Haddad F, Hayek G. Prophylactic ondansetron is effective in the treatment of nausea and vomiting but not on pruritus after cesarean delivery with intrathecal sufentanil-morphine. Journal of Clinical Anesthesia 2002; 14: 183-186 (Pubitemid 34563226)
38. Yazigi A, Chalhoub V, Madi-Jebara S, Haddad F. Ondansetron for prevention of intrathecal opioids-induced pruritus, nausea and vomiting after cesarean delivery. Anesthesia & Analgesia 2004; 98: 264. (Pubitemid 38029892)
39. Nortcliffe SA, Shah J, Buggy DJ. Prevention of postoperative nausea and vomiting after spinal morphine for Caesarean section: comparison of cyclizine, dexamethasone and placebo. British Journal of Anaesthesia 2003; 90: 665-670 (Pubitemid 36592342)
40. Parlow JL, Costache I, Avery N, Turner K. Single-dose haloperidol for the prophylaxis of postoperative nausea and vomiting after intrathecal morphine. Anesthesia & Analgesia 2004; 98: 1072-1076 (Pubitemid 38405423)
41. Saiah M, Borgeat A, Wilder-Smith OH, Rifat K, Suter PM. Epidural-morphine-induced pruritus: propofol versus naloxone. Anesthesia & Analgesia 1994; 78: 1110-1113 (Pubitemid 24164357)
42. Borgeat A, Wilder-Smith OH, Saiah M, Rifat K. Subhypnotic doses of propofol relieve pruritus induced by epidural and intrathecal morphine. Anesthesiology 1992; 76: 510-512
43. Yeh HM, Chen LK, Lin CJ, et al. Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. Anesthesia & Analgesia 2000; 91: 172-175 (Pubitemid 30437081)
44. Kato K, Shimamoto H, Terui K, Yokota K, Miyao H. Delayed respiratory depression associated with 0.15 mg intrathecal morphine for cesarean section: a review of 1915 cases. Journal of Anesthesia 2008; 22: 112-116