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Volumn 81, Issue 11, 2009, Pages 4510-4516

Temperature-programmed natural convection for micromixing and biochemical reaction in a single microfluidic chamber

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL REACTIONS; COMPATIBLE DESIGN; CRITICAL CHALLENGES; MICRO MIXERS; MICRO-MIXING; MICROFABRICATED; MICROFLUIDIC CHAMBERS; MICROFLUIDIC NETWORKS; MODEL APPLICATION; POLYMERASE CHAIN REACTION; SAMPLE TRANSPORT; THERMAL RESPONSE; VIRAL DNA;

EID: 66349083194     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac900512x     Document Type: Article
Times cited : (61)

References (36)
  • 7
    • 66349083395 scopus 로고    scopus 로고
    • 2/s) is 83 min. In contrast, a biochemical reaction such as PCR is usually less than 1 h in microfluidic devices
    • 2/s) is 83 min. In contrast, a biochemical reaction such as PCR is usually less than 1 h in microfluidic devices.
  • 29
    • 33745685253 scopus 로고    scopus 로고
    • In some applications such as protein-folding kinetics fast mixing using an ultra-small volume (i.e., picoliter range) is essential. However, in microfludic networks numerous biochemical reactions such as PCR and DNA hybridization are performed in a chamber, where the volume is more than hundreds of nanoliter, and the micromixing is a pre-process for the reactions. Thus, we believe the use of the parameter (s/μL), which shows the required time to mix solutions at a given chamber-volume, is justified especially for the micromixers in microfluidic networks
    • In some applications such as protein-folding kinetics (Hertzog et. al. Anal. Chem. 2008, 78, 4299-4306), fast mixing using an ultra-small volume (i.e., picoliter range) is essential. However, in microfludic networks numerous biochemical reactions such as PCR and DNA hybridization are performed in a chamber, where the volume is more than hundreds of nanoliter, and the micromixing is a pre-process for the reactions. Thus, we believe the use of the parameter (s/μL), which shows the required time to mix solutions at a given chamber-volume, is justified especially for the micromixers in microfluidic networks.
    • (2008) Anal. Chem. , vol.78 , pp. 4299-4306
    • Hertzog1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.