Sulfasalazine induces haem oxygenase-1 via ROS-dependent Nrf2 signalling, leading to control of neointimal hyperplasia

Cardiovascular Research

Volumn 82, Issue 3, 2009, Pages 550-560

  Kim, Ju Young ^a   Cho, Hyun Jai ^a,b   Sir, Jung Ju ^a,b   Kim, Baek Kyung ^a   Hur, Jin ^a   Youn, Seock Won ^a   Yang, Han Mo ^b   Jun, Soo In ^a   Park, Kyung Woo ^a,b   Hwang, Seok Jae ^a,b   Kwon, Yoo Wook ^b   Lee, Hae Young ^a,b   Kang, Hyun Jae ^a,b   Oh, Byung Hee ^a,b   Park, Young Bae ^a,b   Kim, Hyo Soo ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

Author keywords

Haem oxygenase 1; Nuclear factor erythroid 2 related factor 2; Reactive oxygen species; Sulfasalazine; Vascular injury

Indexed keywords

ACETYLCYSTEINE; CYCLIN DEPENDENT KINASE INHIBITOR 1; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLATELET DERIVED GROWTH FACTOR BB; REACTIVE OXYGEN METABOLITE; SALAZOSULFAPYRIDINE; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTERY INTIMA PROLIFERATION; ARTICLE; CAROTID ARTERY INJURY; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; ENZYME INHIBITION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; APOPTOSIS; CAROTID ARTERY DISEASES; CAROTID ARTERY, COMMON; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE EXPRESSION REGULATION; GRAFT OCCLUSION, VASCULAR; HEME OXYGENASE-1; HYPERPLASIA; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SULFASALAZINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 66249147234     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp072     Document Type: Article

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