Photoacoustic microscopy of cerebral blood-oxygenation dynamics in mice

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7177, Issue , 2009, Pages

  Maslov, Konstantin ^a   Stein, Erich W ^a   Wang, Lihong V ^a  

^a WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

Author keywords

Functional brain imaging; Neuroimaging; Noninvasive imaging; Photoacoustic imaging; Photoacoustic microscopy; Somatosensory cortex

Indexed keywords

FUNCTIONAL BRAIN IMAGING; NEUROIMAGING; NONINVASIVE IMAGING; PHOTOACOUSTIC IMAGING; PHOTOACOUSTIC MICROSCOPY; SOMATOSENSORY CORTEX;

ACOUSTIC WAVES; ASSOCIATIVE STORAGE; BLOOD; BLOOD VESSELS; DYNAMICS; OXYGENATION; OXYGENATORS; PHOTOACOUSTIC EFFECT; PHOTONS; PNEUMATIC DRIVES; PULSE AMPLITUDE MODULATION; ULTRASONIC APPLICATIONS; ULTRASONICS;

ULTRASONIC IMAGING;

EID: 66249146402     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.810036     Document Type: Conference Paper

References (21)

1. M. Hafezparast, A. Ahmad-Annuar, N. W. Wood, S. J. Tabrizi and E. M. C. Fisher, "Mouse models for neurological disease," The Lancet Neurology 1 (4), 215-224 (2002).
2. A. Grinvald, E. Lieke, R. D. Frostig, C. D. Gilbert and T. N. Wiesel, "Functional architecture of cortex revealed by optical imaging of intrinsic signals," Nature 324 (6095), 361-364 (1986).
3. E. M. C. Hillman, "Optical brain imaging in vivo: techniques and applications from animal to man," Journal of biomedical optics 12 (5), 051402 (2007).
4. M. H. Xu and L. H. V. Wang, "Photoacoustic imaging in biomedicine," Review of Scientific Instruments 77 (4), 041101 (2006).
5. H. F. Zhang, K. Maslov, G. Stoica and L. V. Wang, "Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging," Nat Biotechnol 24 (7), 848-851 (2006).
6. R. S. Balaban and V. A. Hampshire, "Challenges in small animal noninvasive imaging," ILAR journal/National Research Council, Institute of Laboratory Animal Resources 42 (3), 248-262 (2001).
7. G. Nair and T. Q. Duong, "Echo-planar BOLD fMRI of mice on a narrow-bore 9.4 T magnet," Magnetic Resonance in Medicine 52 (2), 430-434 (2004).
8. E. T. Ahrens and D. J. Dubowitz, "Peripheral somatosensory fMRI in mouse at 11.7 T," Nmr in Biomedicine 14 (5), 318-324 (2001).
9. X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica and L. H. V. Wang, "Noninvasive laser-induced photoacoustic tomography for structural and functional in vivo imaging of the brain," Nature Biotechnology 21 (7), 803-806 (2003).
10. K. Maslov, G. Stoica and L. V. H. Wang, "In vivo dark-field reflection-mode photoacoustic microscopy," Optics Letters 30 (6), 625-627 (2005).
11. SPIE [American national standard for the safe use of lasers Z136.1], American National Standards Institute, New York, (2000).
12. H. F. Zhang, K. Maslov and L. V. Wang, "In vivo imaging of subcutaneous structures using functional photoacoustic microscopy," Nat. Protocols 2 (4), 797-804 (2007).
13. V. P. Zharov, E. I. Galanzha, E. V. Shashkov, N. G. Khlebtsov, and V. V. Tuchin, "In vivo photoacoustic flow cytometry for monitor of circulating single cancer cells and contrast agents," Optics Letters 31, 3623-3625 (2006).
14. L. V. Wang, S. L. Jacques, and L.-Q. Zheng, "MCML - Monte Carlo modeling of photon transport in multi-layered tissues," Computer Methods and Programs in Biomedicine 47, 131-146 (1995).
15. V. Tuchin, [Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis, Second ed.] SPIE, (2007).
16. G. T. Clement, P. J. White and K. Hynynen, "Enhanced ultrasound transmission through the human skull using shear mode conversion," Journal of the Acoustical Society oj'America 115(3), 1356-1364 (2004).
17. Maslov K., Kim R. Y, Kinra V. K, Pagano N. J. "A new technique for the ultrasonic detection of internal transverse cacks in carbon-fibre/ bismaleimide composite laminates", Composites Science and Technology, 60(12) 2185-2190 (2000).
18. P. J. White, G. T. Clement and K. Hynynen, "Longitudinal and shear mode ultrasound propagation in human skull bone," Ultrasound in Medicine and Biology 32(7), 1085-1096 (2006).
19. M. Born and E. Wolf, [Principles of Optics, Sixth ed.] Pergamon, Cambridge, (2006).
20. M. Sivaramakrishnan, K. Maslov, H.F. Zhang, G. Stoica and L.V. Wang "Limitations of quantitative photoacoustic measurements of blood oxygenation in small vessels," Phys. Med. Biol. 52, 1349-1361 (2007))
21. Parthasarathi, K. & Lipowsky, H.H. "Capillary recruitment in response to tissue hypoxia and its dependence on red blood cell deformability". The American journal of physiology 277, 2145-2157 (1999)