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Volumn 11, Issue 4, 2009, Pages 336-341

Inhibition of platelet activation in rats with severe congestive heart failure by a novel endothelial nitric oxide synthase transcription enhancer

Author keywords

Endothelial function; Heart failure; Infarction; Nitric oxide; Platelets

Indexed keywords

AVE 9488; CARDIOVASCULAR AGENT; CD63 ANTIGEN; CYCLIC GMP; NITRIC OXIDE; PADGEM PROTEIN; PLACEBO; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN;

EID: 66249107380     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1093/eurjhf/hfp005     Document Type: Article
Times cited : (17)

References (39)
  • 1
    • 1842295207 scopus 로고    scopus 로고
    • Ventricular dysfunction and the risk of stroke after myocardial infarction
    • Loh E, St John Sutton M, Wun CC. Ventricular dysfunction and the risk of stroke after myocardial infarction. N Engl J Med 1997;336:251 -257.
    • (1997) N Engl J Med , vol.336 , pp. 251-257
    • Loh, E.1    St John Sutton, M.2    Wun, C.C.3
  • 3
    • 0033117108 scopus 로고    scopus 로고
    • Does heart failure confer a hypercoagulable state? Virchow's triad revisited
    • Lip GY, Gibbs CR. Does heart failure confer a hypercoagulable state? Virchow's triad revisited. J Am Coll Cardiol 1999;33:1424-1426.
    • (1999) J Am Coll Cardiol , vol.33 , pp. 1424-1426
    • Lip, G.Y.1    Gibbs, C.R.2
  • 4
    • 0018646893 scopus 로고
    • Platelet function studies in heart disease. VI. Enhanced platelet aggregate formation activity in congestive heart failure: Inhibition by sodium nitro-prusside
    • Mehta J, Mehta P. Platelet function studies in heart disease. VI. Enhanced platelet aggregate formation activity in congestive heart failure: inhibition by sodium nitro-prusside. Circulation 1979;60:497-503.
    • (1979) Circulation , vol.60 , pp. 497-503
    • Mehta, J.1    Mehta, P.2
  • 5
    • 0033135060 scopus 로고    scopus 로고
    • Usefulness of soluble and surface-bound P-selectin in detecting heightened platelet activity in patients with congestive heart failure
    • O'Connor CM, Gurbel PA, Serebruany VL. Usefulness of soluble and surface-bound P-selectin in detecting heightened platelet activity in patients with congestive heart failure. Am J Cardiol 1999;83:1345-1349.
    • (1999) Am J Cardiol , vol.83 , pp. 1345-1349
    • O'Connor, C.M.1    Gurbel, P.A.2    Serebruany, V.L.3
  • 6
    • 0038150601 scopus 로고    scopus 로고
    • Inhibition of platelet activation in congestive heart failure by selective aldosterone receptor antagonism and ACE-inhibition: Role of endothelial function and platelet VASP phosphorylation
    • Schäfer A, Fraccarollo D, Hildemann S, Christ M, Eigenthaler M, Kobsar A, Walter U, Bauersachs J. Inhibition of platelet activation in congestive heart failure by selective aldosterone receptor antagonism and ACE-inhibition: role of endothelial function and platelet VASP phosphorylation. Thromb Haemost 2003; 89:1024-1030.
    • (2003) Thromb Haemost , vol.89 , pp. 1024-1030
    • Schäfer, A.1    Fraccarollo, D.2    Hildemann, S.3    Christ, M.4    Eigenthaler, M.5    Kobsar, A.6    Walter, U.7    Bauersachs, J.8
  • 8
    • 0026546129 scopus 로고
    • Concentration and regulation of cyclic nucleotides, cyclic-nucleotide-dependent protein kinases and one of their major substrates in human platelets: Estimating the rate of cAMP-regulated and cGMP-regulated protein phosphorylation in intact cells
    • Eigenthaler M, Nolte C, Halbruegge M, Walter U. Concentration and regulation of cyclic nucleotides, cyclic-nucleotide-dependent protein kinases and one of their major substrates in human platelets: estimating the rate of cAMP-regulated and cGMP-regulated protein phosphorylation in intact cells. Eur J Biochem 1992; 205:471-481.
    • (1992) Eur J Biochem , vol.205 , pp. 471-481
    • Eigenthaler, M.1    Nolte, C.2    Halbruegge, M.3    Walter, U.4
  • 9
    • 0039207312 scopus 로고    scopus 로고
    • The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function
    • Aszódi A, Pfeifer A, Ahmad M, Glauner M, Zhou X-H, Ny L, Andersson K-E, Kehrel B, Offermanns S, Faessler R. The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function. EMBO J 1999;18:37-48.
    • (1999) EMBO J , vol.18 , pp. 37-48
    • Aszódi, A.1    Pfeifer, A.2    Ahmad, M.3    Glauner, M.4    Zhou, X.-H.5    Ny, L.6    Andersson, K.-E.7    Kehrel, B.8    Offermanns, S.9    Faessler, R.10
  • 11
    • 0028146120 scopus 로고
    • Phosphoryl-ation of focal adhesion vasodilator-stimulated phosphoprotein at Ser 157 in intact human platelets correlates with fibrinogen receptor inhibition
    • Horstrup K, Jablonka B, Honig-Liedl P,Just M, Kochsiek K, Walter U. Phosphoryl-ation of focal adhesion vasodilator-stimulated phosphoprotein at Ser 157 in intact human platelets correlates with fibrinogen receptor inhibition. EurJ Biochem 1994; 225:21 -27.
    • (1994) EurJ Biochem , vol.225 , pp. 21-27
    • Horstrup, K.1    Jablonka, B.2    Honig-Liedl, P.3    Just, M.4    Kochsiek, K.5    Walter, U.6
  • 13
    • 0037298864 scopus 로고    scopus 로고
    • Endothelium-dependent and -independent relaxation and VASP serines 157/239 phosphorylation by cyclic nucleotide-elevating vasodilators in rat aorta
    • Schäfer A, Vollkommer T, Burkhardt M, Bauersachs J, Münzel T, Walter U, Smolenski A. Endothelium-dependent and -independent relaxation and VASP serines 157/239 phosphorylation by cyclic nucleotide-elevating vasodilators in rat aorta. Biochem Pharmacol 2003;65:397-405.
    • (2003) Biochem Pharmacol , vol.65 , pp. 397-405
    • Schäfer, A.1    Vollkommer, T.2    Burkhardt, M.3    Bauersachs, J.4    Münzel, T.5    Walter, U.6    Smolenski, A.7
  • 14
    • 0033661723 scopus 로고    scopus 로고
    • VASP protects actin filaments from gelsolin: An in vitro study with implications for platelet actin reorganizations
    • Bearer EL, Prakash JM, Manchester RD, Allen PG. VASP protects actin filaments from gelsolin: an in vitro study with implications for platelet actin reorganizations. Cell Motil Cytoskeleton 2000;47:351 -364.
    • (2000) Cell Motil Cytoskeleton , vol.47 , pp. 351-364
    • Bearer, E.L.1    Prakash, J.M.2    Manchester, R.D.3    Allen, P.G.4
  • 15
    • 0035312298 scopus 로고    scopus 로고
    • Actin-based motility: Stop and go with Ena/ VASP proteins
    • Reinhard M, Jarchau T, Walter U. Actin-based motility: stop and go with Ena/ VASP proteins. Trends Biochem Sci 2001;26:243-249.
    • (2001) Trends Biochem Sci , vol.26 , pp. 243-249
    • Reinhard, M.1    Jarchau, T.2    Walter, U.3
  • 20
    • 0034711470 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction
    • Oelze M, Mollnau H, Hoffmann N, Warnholtz A, Bodenschatz M, Smolenski A, Walter U, Skatchkov M, Meinertz T, Munzel T. Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction. Circ Res 2000;87:999-1005.
    • (2000) Circ Res , vol.87 , pp. 999-1005
    • Oelze, M.1    Mollnau, H.2    Hoffmann, N.3    Warnholtz, A.4    Bodenschatz, M.5    Smolenski, A.6    Walter, U.7    Skatchkov, M.8    Meinertz, T.9    Munzel, T.10
  • 26
    • 53749096012 scopus 로고    scopus 로고
    • Improvement of left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction
    • Fraccarollo D, Widder J, Galuppo P, Thum T, Tsikas D, Hoffmann M, Ruetten H, Ertl G, Bauersachs J. Improvement of left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction. Circulation 2008;118:818-827.
    • (2008) Circulation , vol.118 , pp. 818-827
    • Fraccarollo, D.1    Widder, J.2    Galuppo, P.3    Thum, T.4    Tsikas, D.5    Hoffmann, M.6    Ruetten, H.7    Ertl, G.8    Bauersachs, J.9
  • 27
    • 0030691955 scopus 로고    scopus 로고
    • Chronic endothelin receptor blockade attenuates progressive ventricular dilatation and improves cardiac function in rats with myocardial infarction. Possible involvement of myocardial endothelin system in ventricular remodeling
    • Fraccarollo D, Hu K, Galuppo P, Gaudron P, Ertl G. Chronic endothelin receptor blockade attenuates progressive ventricular dilatation and improves cardiac function in rats with myocardial infarction. Possible involvement of myocardial endothelin system in ventricular remodeling. Circulation 1997;96:3963-3973.
    • (1997) Circulation , vol.96 , pp. 3963-3973
    • Fraccarollo, D.1    Hu, K.2    Galuppo, P.3    Gaudron, P.4    Ertl, G.5
  • 28
    • 0035964390 scopus 로고    scopus 로고
    • Improvement of left ventricular remodeling and function by hydroxymethylglutaryl coenzyme a reductase inhibition with cerivastatin in rats with heart failure after myocardial infarction
    • Bauersachs J, Galuppo P, Fraccarollo D, Christ M, Ertl G. Improvement of left ventricular remodeling and function by hydroxymethylglutaryl coenzyme a reductase inhibition with cerivastatin in rats with heart failure after myocardial infarction. Circulation 2001;104:982-985.
    • (2001) Circulation , vol.104 , pp. 982-985
    • Bauersachs, J.1    Galuppo, P.2    Fraccarollo, D.3    Christ, M.4    Ertl, G.5
  • 29
    • 0027998055 scopus 로고
    • Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan)
    • TeerlinkJR, Loffler BM, Hess P, MaireJP, Clozel M, ClozelJP. Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan). Circulation 1994;90:2510-2518.
    • (1994) Circulation , vol.90 , pp. 2510-2518
    • Teerlink, J.R.1    Loffler, B.M.2    Hess, P.3    Maire, J.P.4    Clozel, M.5    Clozel, J.P.6
  • 30
    • 0032873146 scopus 로고    scopus 로고
    • Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets
    • Schwarz UR, Geiger J, Walter U, Eigenthaler M. Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets. Thromb Haemost 1999;82:1145-1152.
    • (1999) Thromb Haemost , vol.82 , pp. 1145-1152
    • Schwarz, U.R.1    Geiger, J.2    Walter, U.3    Eigenthaler, M.4
  • 31
    • 0032493663 scopus 로고    scopus 로고
    • Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody
    • Smolenski A, Bachmann C, Reinhard K, Honig-Liedl P, Jarchau T, Hoschuetzky H, Walter U. Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody. J Biol Chem 1998;273:20029-20035.
    • (1998) J Biol Chem , vol.273 , pp. 20029-20035
    • Smolenski, A.1    Bachmann, C.2    Reinhard, K.3    Honig-Liedl, P.4    Jarchau, T.5    Hoschuetzky, H.6    Walter, U.7
  • 33
    • 2442583364 scopus 로고    scopus 로고
    • Reduced basal nitric oxide bioavailability and platelet activation in young spontaneously hypertensive rats
    • Schäfer A, Widder J, Eigenthaler M, Ertl G, Bauersachs J. Reduced basal nitric oxide bioavailability and platelet activation in young spontaneously hypertensive rats. Biochem Pharmacol 2004;67:2273- 2279.
    • (2004) Biochem Pharmacol , vol.67 , pp. 2273-2279
    • Schäfer, A.1    Widder, J.2    Eigenthaler, M.3    Ertl, G.4    Bauersachs, J.5
  • 34
    • 0037214449 scopus 로고    scopus 로고
    • Regulation of endothelium-derived vasoactive autacoid production by hemodynamic forces
    • Busse R, Fleming I. Regulation of endothelium-derived vasoactive autacoid production by hemodynamic forces. Trends Pharmacol Sci 2003;24:24-29.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 24-29
    • Busse, R.1    Fleming, I.2
  • 35
    • 0038206805 scopus 로고    scopus 로고
    • Addition of the selective aldosterone receptor antagonist eplerenone to ACE inhibition in heart failure: Effect of endothelial function
    • Schäfer A, Fraccarollo D, Hildemann S, Tas P, Ertl G, Bauersachs J. Addition of the selective aldosterone receptor antagonist eplerenone to ACE inhibition in heart failure: effect of endothelial function. Cardiovasc Res 2003;58:655-662.
    • (2003) Cardiovasc Res , vol.58 , pp. 655-662
    • Schäfer, A.1    Fraccarollo, D.2    Hildemann, S.3    Tas, P.4    Ertl, G.5    Bauersachs, J.6
  • 37
    • 0034613254 scopus 로고    scopus 로고
    • Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin
    • Harbeck B, Huttelmaier S, Schluter K, Jockusch BM, Illenberger S. Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin. J Biol Chem 2000;275:30817-30825.
    • (2000) J Biol Chem , vol.275 , pp. 30817-30825
    • Harbeck, B.1    Huttelmaier, S.2    Schluter, K.3    Jockusch, B.M.4    Illenberger, S.5
  • 38
    • 0035799349 scopus 로고    scopus 로고
    • Abnormalities of hemorheological, endothelial, and platelet function in patients with chronic heart failure in sinus rhythm: Effects of angiotensin-converting enzyme inhibitor and beta-blocker therapy
    • Gibbs CR, Blann AD, Watson RD, Lip GY. Abnormalities of hemorheological, endothelial, and platelet function in patients with chronic heart failure in sinus rhythm: effects of angiotensin-converting enzyme inhibitor and beta-blocker therapy. Circulation 2001;103:1746-1751.
    • (2001) Circulation , vol.103 , pp. 1746-1751
    • Gibbs, C.R.1    Blann, A.D.2    Watson, R.D.3    Lip, G.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.