Investigation of novel bis- and tris-tetraazamacrocycles for use in the copper-64 (64Cu) radiolabeling of antibodies with potential to increase the therapeutic index for drug targeting

Bioconjugate Chemistry

Volumn 20, Issue 5, 2009, Pages 868-876

  Ramli, Martalena ^a,b,c   Smith, Suzanne V ^b   Lindoy, Leonard F ^c  

^a Kawasan PUSPIPTEK   (Indonesia)

^b AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIS TETRAAZAMACROCYCLE; COPPER 64; CUPRIC ION; LIGAND; MACROCYCLIC COMPOUND; MONOCLONAL ANTIBODY B.72.3; MONOTETRAAZAMACROCYCLE; TRIS TETRAAZAMACROCYCLE; UNCLASSIFIED DRUG; ANTIBODY CONJUGATE; COPPER; HETEROCYCLIC COMPOUND; MONOCLONAL ANTIBODY; ORGANOMETALLIC COMPOUND;

ANTIBODY LABELING; ARTICLE; CONJUGATION; DRUG STRUCTURE; DRUG TARGETING; HUMAN; IMMUNOREACTIVITY; ISOTOPE LABELING; PH; PROTEIN BLOOD LEVEL; TEMPERATURE; TIME; TUMOR LOCALIZATION; ANIMAL; BLOOD; CHEMISTRY; DRUG STABILITY; FEMALE; IMMUNOLOGY; METABOLISM; MOUSE; NUDE MOUSE; PROCEDURES; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; AZA COMPOUNDS; CELL LINE, TUMOR; COPPER RADIOISOTOPES; DRUG STABILITY; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOCONJUGATES; ISOTOPE LABELING; LIGANDS; MACROCYCLIC COMPOUNDS; MICE; MICE, NUDE; ORGANOMETALLIC COMPOUNDS;

EID: 66149180579     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc800337d     Document Type: Article

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