메뉴 건너뛰기




Volumn 101, Issue 5, 2009, Pages 806-812

Role of antithrombin concentrate in treatment of hereditary antithrombin deficiency: An update

Author keywords

Antithrombin; Hereditary antithrombin deficiency; Thromboprophylaxis; Venous thromboembolism

Indexed keywords

ANTITHROMBIN; ANTITHROMBIN III; ANTITHROMBIN III CONCENTRATE; FRESH FROZEN PLASMA; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; RECOMBINANT ANTITHROMBIN III; THROMBATE; TISSUE FACTOR PATHWAY INHIBITOR; UNCLASSIFIED DRUG; VITAMIN K GROUP;

EID: 66149176918     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH08-10-0672     Document Type: Review
Times cited : (95)

References (69)
  • 1
    • 34347393477 scopus 로고    scopus 로고
    • Hereditary and acquired antithrombin deficiency: Epidemiology, pathogenesis and treatment options
    • DOI 10.2165/00003495-200767100-00005
    • Maclean PS, Tait RC. Hereditary and acquired antithrombin deficiency: epidemiology, pathogenesis and treatment options. Drugs 2007; 67: 1429-1440. (Pubitemid 47026392)
    • (2007) Drugs , vol.67 , Issue.10 , pp. 1429-1440
    • Maclean, P.S.1    Tait, R.C.2
  • 2
    • 0036283477 scopus 로고    scopus 로고
    • Selective inhibition of coagulation factors: Advances in antithrombotic therapy
    • Bauer KA. Selective inhibition of coagulation factors: advances in antithrombotic therapy. Semin Thromb Hemost 2002; 28 (Suppl 2): 15-24. (Pubitemid 34634350)
    • (2002) Seminars in Thrombosis and Hemostasis , vol.28 , Issue.SUPPL. 2 , pp. 15-24
    • Bauer, K.A.1
  • 3
    • 0031835086 scopus 로고    scopus 로고
    • Uses of antithrombin III concentrate in congenital and acquired deficiency states
    • Bucur SZ, Levy JH, Despotis GJ, et al. Uses of antithrombin III concentrate in congenital and acquired deficiency states. Transfusion 1998; 38: 481-498. (Pubitemid 28287507)
    • (1998) Transfusion , vol.38 , Issue.5 , pp. 481-498
    • Bucur, S.Z.1    Levy, J.H.2    Despotis, G.J.3    Spiess, B.D.4    Hillyer, C.D.5
  • 6
    • 33846466747 scopus 로고    scopus 로고
    • Regulation of Thrombin Activity-Pharmacologic and Structural Aspects
    • DOI 10.1016/j.hoc.2006.11.008, PII S0889858806001924, Inflamation, Hemostasis, and Blood Conservation Strategies
    • Tanaka KA, Levy JH. Regulation of thrombin activity - pharmacologic and structural aspects. Hematol Oncol Clin North Am 2007; 21: 33-50. (Pubitemid 46156984)
    • (2007) Hematology/Oncology Clinics of North America , vol.21 , Issue.1 , pp. 33-50
    • Tanaka, K.A.1    Levy, J.H.2
  • 7
    • 0028079403 scopus 로고
    • An overview of the mechanism of action of antithrombin and its inherited deficiency states
    • discussion S59-64
    • Blajchman MA. An overview of the mechanism of action of antithrombin and its inherited deficiency states. Blood Coagul Fibrinolysis 1994; 5 (Suppl 1): S5-11; discussion S59-64.
    • (1994) Blood Coagul Fibrinolysis , vol.5 , Issue.SUPPL. 1
    • Blajchman, M.A.1
  • 9
    • 0242351640 scopus 로고    scopus 로고
    • Interactions between coagulation and inflammation
    • DOI 10.1080/00365540310015638
    • Opal SM. Interactions between coagulation and inflammation. Scand J Infect Dis 2003; 35: 545-554. (Pubitemid 37336871)
    • (2003) Scandinavian Journal of Infectious Diseases , vol.35 , Issue.9 , pp. 545-554
    • Opal, S.M.1
  • 11
    • 0024418642 scopus 로고
    • Clinical experience with antithrombin III concentrate in treatment of congenital and acquired deficiency of antithrombin
    • The Antithrombin III Study Group
    • Schwartz RS, Bauer KA, Rosenberg RD, et al. The Antithrombin III Study Group. Clinical experience with antithrombin III concentrate in treatment of congenital and acquired deficiency of antithrombin. Am J Med 1989; 87(Suppl 3B): 53S-60S.
    • (1989) Am J Med , vol.87 , Issue.SUPPL. 3B
    • Schwartz, R.S.1    Bauer, K.A.2    Rosenberg, R.D.3
  • 12
    • 0023261782 scopus 로고
    • The pathophysiology of the prethrombotic state in humans: Insights gained from studies using markers of hemostatic system activation
    • Bauer KA, Rosenberg RD. The pathophysiology of the prethrombotic state in humans: insights gained from studies using markers of hemostatic system activation. Blood 1987; 70: 343-350. (Pubitemid 17142912)
    • (1987) Blood , vol.70 , Issue.2 , pp. 343-350
    • Bauer, K.A.1    Rosenberg, R.D.2
  • 13
    • 0024447029 scopus 로고
    • Congenital antithrombin III deficiency. Incidence and clinical features
    • Hirsh J, Piovellá F, Pini M. Congenital antithrombin III deficiency. Incidence and clinical features. Am J Med 1989; 87 (Suppl 3B): 34S-38S. (Pubitemid 19249549)
    • (1989) American Journal of Medicine , vol.87 , Issue.3 B
    • Hirsch, J.1    Piovella, F.2    Pini, M.3
  • 16
    • 0024457904 scopus 로고
    • Acquired antithrombin III deficiency: Laboratory diagnosis, incidence, clinical implications, and treatment with antithrombin III concentrate
    • Buller HR, ten Cate JW. Acquired antithrombin III deficiency: laboratory diagnosis, incidence, clinical implications, and treatment with antithrombin III concentrate. Am J Med 1989; 87 (3B): 44S-48S.
    • (1989) Am J Med , vol.87 , Issue.3 B
    • Buller, H.R.1    Ten Cate, J.W.2
  • 18
    • 0026792857 scopus 로고
    • Maturation of the hemostatic system during childhood
    • Andrew M, Vegh P, Johnston M, et al. Maturation of the hemostatic system during childhood. Blood 1992; 80: 1998-2005.
    • (1992) Blood , vol.80 , pp. 1998-2005
    • Andrew, M.1    Vegh, P.2    Johnston, M.3
  • 19
    • 33746642540 scopus 로고    scopus 로고
    • Pediatric reference intervals for uncommon bleeding and thrombotic disorders
    • DOI 10.1016/j.jpeds.2006.04.008, PII S0022347606003106
    • Flanders MM, Phansalkar AR, Crist RA, et al. Pediatric reference intervals for uncommon bleeding and thrombotic disorders. J Pediatr 2006; 149: 275-277. (Pubitemid 44144496)
    • (2006) Journal of Pediatrics , vol.149 , Issue.2 , pp. 275-277
    • Flanders, M.M.1    Phansalkar, A.R.2    Crist, R.A.3    Roberts, W.L.4    Rodgers, G.M.5
  • 20
    • 0034791001 scopus 로고    scopus 로고
    • Investigation and management of heritable thrombophilia
    • Haemostasis and Thrombosis Task Force of the British Committee for Standards in Haematology
    • Haemostasis and Thrombosis Task Force of the British Committee for Standards in Haematology. Investigation and management of heritable thrombophilia. Br J Haematol 2001; 114: 512-528.
    • (2001) Br J Haematol , vol.114 , pp. 512-528
  • 21
    • 0036881507 scopus 로고    scopus 로고
    • Antithrombin deficiency: Issues in laboratory diagnosis
    • Kottke-Marchant K, Duncan A. Antithrombin deficiency: issues in laboratory diagnosis. Arch Pathol Lab Med 2002; 126: 1326-1336.
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 1326-1336
    • Kottke-Marchant, K.1    Duncan, A.2
  • 22
    • 0030037196 scopus 로고    scopus 로고
    • Molecular genetics of antithrombin deficiency
    • DOI 10.1016/S0268-960X(96)90034-X
    • Lane DA, Kunz G, Olds RJ, et al. Molecular genetics of antithrombin deficiency. Blood Rev 1996; 10: 59-74. (Pubitemid 26234214)
    • (1996) Blood Reviews , vol.10 , Issue.2 , pp. 59-74
    • Lane, D.A.1    Kunz, G.2    Olds, R.J.3    Thein, S.L.4
  • 23
    • 0035912152 scopus 로고    scopus 로고
    • Genetic susceptibility to venous thrombosis
    • DOI 10.1056/NEJM200104193441607
    • Seligsohn U, Lubetsky A. Genetic susceptibility to venous thrombosis. N Engl J Med 2001; 344: 1222-1231. (Pubitemid 32319498)
    • (2001) New England Journal of Medicine , vol.344 , Issue.16 , pp. 1222-1231
    • Seligsohn, U.1    Lubetsky, A.2
  • 26
    • 0037346228 scopus 로고    scopus 로고
    • Clinical and laboratory evaluation of thrombophilia
    • DOI 10.1016/S0272-5231(02)00054-0
    • Perry SL, Ortel TL. Clinical and laboratory evaluation of thrombophilia. Clin Chest Med 2003; 24: 153-170. (Pubitemid 36363145)
    • (2003) Clinics in Chest Medicine , vol.24 , Issue.1 , pp. 153-170
    • Perry, S.L.1    Ortel, T.L.2
  • 28
    • 0019579602 scopus 로고
    • Antithrombin III deficiency and thromboembolism
    • Thaler E, Lechner K. Antithrombin III deficiency and thromboembolism. Clin Haematol 1981; 10: 369-390.
    • (1981) Clin Haematol , vol.10 , pp. 369-390
    • Thaler, E.1    Lechner, K.2
  • 29
    • 44949117826 scopus 로고    scopus 로고
    • The risk of symptomatic pulmonary embolism due to proximal deep venous thrombosis differs in patients with different types of inherited thrombophila
    • Rossi E, Sz T, Ciminello A, et al. The risk of symptomatic pulmonary embolism due to proximal deep venous thrombosis differs in patients with different types of inherited thrombophila. Thromb Haemost. 2008; 99: 1030-1034.
    • (2008) Thromb Haemost , vol.99 , pp. 1030-1034
    • Rossi, E.1    Sz, T.2    Ciminello, A.3
  • 30
    • 45949094478 scopus 로고    scopus 로고
    • Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    • Bates SM, Greer IA, Pabinger I, et al. Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133 (6 Suppl): 844S-886S.
    • (2008) Chest , vol.133 , Issue.6 SUPPL.
    • Bates, S.M.1    Greer, I.A.2    Pabinger, I.3
  • 34
    • 33751288115 scopus 로고    scopus 로고
    • Thrombin during cardiopulmonary bypass
    • Edmunds LH Jr, Colman RW. Thrombin during cardiopulmonary bypass. Ann Thorac Surg 2006; 82: 2315-2322.
    • (2006) Ann Thorac Surg , vol.82 , pp. 2315-2322
    • Edmunds Jr., L.H.1    Colman, R.W.2
  • 37
    • 0033807417 scopus 로고    scopus 로고
    • A randomized trial of antithrombin concentrate for treatment of heparin resistance
    • Williams MR, D'Ambra AB, Beck JR, et al. A randomized trial of antithrombin concentrate for treatment of heparin resistance. Ann Thorac Surg 2000; 70: 873-877.
    • (2000) Ann Thorac Surg , vol.70 , pp. 873-877
    • Williams, M.R.1    D'Ambra, A.B.2    Beck, J.R.3
  • 38
    • 4644308426 scopus 로고    scopus 로고
    • Heparin and low-molecular-weight heparin
    • Hirsh J, Raschke R. Heparin and low-molecular-weight heparin. Chest 2004; 126: 188S-203S.
    • (2004) Chest , vol.126
    • Hirsh, J.1    Raschke, R.2
  • 39
    • 31044449335 scopus 로고    scopus 로고
    • Risks and side effects of therapy with plasma and plasma fractions
    • DOI 10.1016/j.beha.2005.01.033, PII S1521692605000344
    • MacLennan S, Barbara JA. Risks and side effects of therapy with plasma and plasma fractions. Best Pract Res Clin Haematol 2006; 19: 169-189. (Pubitemid 43118870)
    • (2006) Best Practice and Research: Clinical Haematology , vol.19 , Issue.1 , pp. 169-189
    • MacLennan, S.1    Barbara, J.A.J.2
  • 40
    • 23044487733 scopus 로고    scopus 로고
    • West Nile virus among blood donors in the United States, 2003 and 2004
    • Stramer SL, Fang CT, Foster GA, et al. West Nile virus among blood donors in the United States, 2003 and 2004. N Engl J Med 2005; 353: 451-459.
    • (2005) N Engl J Med , vol.353 , pp. 451-459
    • Stramer, S.L.1    Fang, C.T.2    Foster, G.A.3
  • 41
    • 66149160823 scopus 로고    scopus 로고
    • Research Triangle Park, NC: Talecris Biotherapeutics, Inc
    • Thrombate III® [package insert]. Research Triangle Park, NC: Talecris Biotherapeutics, Inc; 2005.
    • (2005) Thrombate III® [Package Insert]
  • 42
    • 0024459735 scopus 로고
    • Purification and large-scale preparation of antithrombin III
    • Hoffman DL. Purification and large-scale preparation of antithrombin III. Am J Med 1989; 87 (3B): 23S-26S.
    • (1989) Am J Med , vol.87 , Issue.3 B
    • Hoffman, D.L.1
  • 43
    • 0041519051 scopus 로고    scopus 로고
    • Manufacturing process of Anti-thrombin III concentrate: Viral safety validation studies and effect of column re-use on viral clearance
    • DOI 10.1016/S1045-1056(03)00035-6
    • Morrica A, Nardini C, Falbo A, et al. Manufacturing process of anti-thrombin III concentrate: viral safety validation studies and effect of column re-use on viral clearance. Biologicals 2003; 31: 165-173. (Pubitemid 36993712)
    • (2003) Biologicals , vol.31 , Issue.3 , pp. 165-173
    • Morrica, A.1    Nardini, C.2    Falbo, A.3    Bailey, A.C.4    Bucci, E.5
  • 44
    • 0025017717 scopus 로고
    • Evaluation of the safety, recovery, half-life, and clinical efficacy of antithrombin III (human) in patients with hereditary antithrombin III deficiency
    • Cooperative Study Group
    • Menache D, O'Malley JP, Schorr JB, et al. Cooperative Study Group. Evaluation of the safety, recovery, half-life, and clinical efficacy of antithrombin III (human) in patients with hereditary antithrombin III deficiency. Blood 1990; 75: 33-39.
    • (1990) Blood , vol.75 , pp. 33-39
    • Menache, D.1    O'Malley, J.P.2    Schorr, J.B.3
  • 45
    • 0026687491 scopus 로고
    • Safety of virus inactivated antithrombin III concentrate antithrombin III immuno (AT III)
    • Preiss DU, Abdullah D, Eberspacher B, et al. Safety of virus inactivated antithrombin III concentrate antithrombin III immuno (AT III). Thromb Res 1992; 65: 677-686.
    • (1992) Thromb Res , vol.65 , pp. 677-686
    • Preiss, D.U.1    Abdullah, D.2    Eberspacher, B.3
  • 47
    • 0037343212 scopus 로고    scopus 로고
    • Use of recombinant human antithrombin in patients with congenital antithrombin deficiency undergoing surgical procedures
    • DOI 10.1046/j.1537-2995.2003.00315.x
    • Konkle BA, Bauer KA, Weinstein R, et al. Use of recombinant human antithrombin in patients with congenital antithrombin deficiency undergoing surgical procedures. Transfusion 2003; 43: 390-394. (Pubitemid 36351132)
    • (2003) Transfusion , vol.43 , Issue.3 , pp. 390-394
    • Konkle, B.A.1    Bauer, K.A.2    Weinstein, R.3    Greist, A.4    Holmes, H.E.5    Bonfiglio, J.6
  • 48
    • 42249086482 scopus 로고    scopus 로고
    • Antithrombin alfa in hereditary antithrombin deficient patients: A phase 3 study of prophylactic intravenous administration in high risk situations
    • Tiede A, Tait RC, Shaffer DW, et al. Antithrombin alfa in hereditary antithrombin deficient patients: A phase 3 study of prophylactic intravenous administration in high risk situations. Thromb Haemost 2008; 99: 616-622.
    • (2008) Thromb Haemost , vol.99 , pp. 616-622
    • Tiede, A.1    Tait, R.C.2    Shaffer, D.W.3
  • 49
    • 0036157110 scopus 로고    scopus 로고
    • Inherited thrombophilias in pregnant patients: Detection and treatment paradigm
    • DOI 10.1016/S0029-7844(01)01760-4, PII S0029784401017604
    • Lockwood CJ. Inherited thrombophilias in pregnant patients: detection and treatment paradigm. Obstet Gynecol 2002; 99: 333-341. (Pubitemid 34114007)
    • (2002) Obstetrics and Gynecology , vol.99 , Issue.2 , pp. 333-341
    • Lockwood, C.J.1
  • 50
    • 0037443934 scopus 로고    scopus 로고
    • Thrombophilic disorders and fetal loss: A meta-analysis
    • DOI 10.1016/S0140-6736(03)12771-7
    • Rey E, Kahn SR, David M, et al. Thrombophilic disorders and fetal loss: a meta-analysis. Lancet 2003; 361: 901-908. (Pubitemid 36335814)
    • (2003) Lancet , vol.361 , Issue.9361 , pp. 901-908
    • Rey, E.1    Kahn, S.R.2    David, M.3    Shrier, I.4
  • 52
    • 0020030303 scopus 로고
    • Pregnancy in women with congenital antithrombin III deficiency: Experience of treatment with heparin and antithrombin
    • Hellgren M, Tengborn L, Abildgaard U. Pregnancy in women with congenital antithrombin III deficiency: experience of treatment with heparin and antithrombin. Gynecol Obstet Invest 1982; 14: 127-141.
    • (1982) Gynecol Obstet Invest , vol.14 , pp. 127-141
    • Hellgren, M.1    Tengborn, L.2    Abildgaard, U.3
  • 55
    • 0024993079 scopus 로고
    • Guidelines on the investigation and management of thrombophilia
    • British Committee for Standards in Haematology. The British Committee for Standards in Haematology
    • British Committee for Standards in Haematology. Guidelines on the investigation and management of thrombophilia. The British Committee for Standards in Haematology. J Clin Pathol 1990; 43: 703-709.
    • (1990) J Clin Pathol , vol.43 , pp. 703-709
  • 56
    • 0026527093 scopus 로고
    • Prophylaxis of thromboembolism during pregnancy in hereditary AT-III deficiency
    • Brenner B, Tavori S, Tatarsky I. Prophylaxis of thromboembolism during pregnancy in hereditary AT-III deficiency. Am J Hematol 1992; 39: 71-72.
    • (1992) Am J Hematol , vol.39 , pp. 71-72
    • Brenner, B.1    Tavori, S.2    Tatarsky, I.3
  • 57
    • 0026055356 scopus 로고
    • Effective prophylaxis of thrombosis by antithrombin III concentrate in a pregnant woman with congenital antithrombin III deficiency: Relations between plasma antithrombin III activity and the plasma levels of hemostatic molecular markers
    • Inomoto T, Takamoto M, Tamura R, et al. Effective prophylaxis of thrombosis by antithrombin III concentrate in a pregnant woman with congenital antithrombin III deficiency: relations between plasma antithrombin III activity and the plasma levels of hemostatic molecular markers. Haemostasis 1991; 21: 147-154.
    • (1991) Haemostasis , vol.21 , pp. 147-154
    • Inomoto, T.1    Takamoto, M.2    Tamura, R.3
  • 58
    • 0025060842 scopus 로고
    • Pregnancy, antithrombin III deficiency and venous thrombosis: Report of another case
    • Megha A, Finzi G, Poli T, et al. Pregnancy, antithrombin III deficiency and venous thrombosis: report of another case. Acta Haematol 1990; 83: 111. (Pubitemid 20043283)
    • (1990) Acta Haematologica , vol.83 , Issue.2 , pp. 111
    • Megha, A.1    Finzi, G.2    Poli, T.3    Manotti, C.4    Dettori, A.G.5
  • 59
    • 0027217289 scopus 로고
    • Congenital antithrombin III deficient neonate treated with antithrombin III concentrates
    • DOI 10.1016/0049-3848(93)90127-A
    • Shiozaki A, Arai T, Izumi R, et al. Congenital antithrombin III deficient neonate treated with antithrombin III concentrates. Thromb Res 1993; 70: 211-216. (Pubitemid 23151327)
    • (1993) Thrombosis Research , vol.70 , Issue.3 , pp. 211-216
    • Shiozaki, A.1    Arai, T.2    Izumi, R.3    Niiya, K.4    Sakuragawa, N.5
  • 60
    • 0022911905 scopus 로고
    • Antithrombin III concentrate. Thromboprophylaxis during pregnancy in a patient with congenital antithrombin III deficiency
    • Tengborn L, Bengtsson T. Antithrombin III concentrate. Thromboprophylaxis during pregnancy in a patient with congenital antithrombin III deficiency. Acta Obstet Gynecol Scand 1986; 65: 375-376.
    • (1986) Acta Obstet Gynecol Scand , vol.65 , pp. 375-376
    • Tengborn, L.1    Bengtsson, T.2
  • 63
    • 0021337405 scopus 로고
    • Management of planned pregnancy in a patient with congenital antithrombin III deficiency
    • Samson D, Stirling Y, Woolf L, et al. Management of planned pregnancy in a patient with congenital antithrombin III deficiency. Br J Haematol 1984; 56: 243-249. (Pubitemid 14175627)
    • (1984) British Journal of Haematology , vol.56 , Issue.2 , pp. 243-249
    • Samson, D.1    Stirling, Y.2    Woolf, L.3
  • 64
    • 0024310596 scopus 로고
    • Prophylaxis during surgery in antithrombin III deficiency with low dose of concentrates
    • DOI 10.1016/0049-3848(89)90263-6
    • Blanco AN, Meschengieser S, Penalva LB, et al. Prophylaxis during surgery in antithrombin III deficiency with low dose of concentrates. Thromb Res 1989; 56: 497-499. (Pubitemid 20003604)
    • (1989) Thrombosis Research , vol.56 , Issue.3 , pp. 497-499
    • Blanco, A.N.1    Meschengieser, S.2    Penalva, L.B.3    Lazzari, M.A.4
  • 65
    • 0029589898 scopus 로고
    • Use of antithrombin III concentrates to correct antithrombin III deficiency during vascular surgery
    • DOI 10.1016/S0741-5214(95)70072-2
    • Jackson MR, Olsen SB, Gomez ER, et al. Use of antithrombin III concentrates to correct antithrombin III deficiency during vascular surgery. J Vasc Surg 1995; 22: 804-807. (Pubitemid 26013939)
    • (1995) Journal of Vascular Surgery , vol.22 , Issue.6 , pp. 804-807
    • Jackson, M.R.1
  • 66
    • 85047692241 scopus 로고
    • Treatment of congenital antithrombin III deficiency with concentrates
    • Mannucci PM, Boyer C, Wolf M, et al. Treatment of congenital antithrombin III deficiency with concentrates. Br J Haematol 1982; 50: 531-535. (Pubitemid 12184018)
    • (1982) British Journal of Haematology , vol.50 , Issue.3 , pp. 531-535
    • Mannucci, P.M.1    Boyer, C.2    Wolf, M.3
  • 67
    • 0030930446 scopus 로고    scopus 로고
    • Indicators of fibrinolysis during cardiopulmonary bypass after exogenous antithrombin-III administration for acquired antithrombin III deficiency
    • DOI 10.1016/S1053-0770(97)90172-5
    • Van Norman GA, Gernsheimer T, Chandler WL, et al. Indicators of fibrinolysis during cardiopulmonary bypass after exogenous antithrombin-III administration for acquired antithrombin III deficiency. J Cardiothorac Vasc Anesth 1997; 11: 760-763. (Pubitemid 27408675)
    • (1997) Journal of Cardiothoracic and Vascular Anesthesia , vol.11 , Issue.6 , pp. 760-763
    • Van Norman, G.A.1    Gernsheimer, T.2    Chandler, W.L.3    Cochran, R.P.4    Spiess, B.D.5
  • 68
    • 66149176015 scopus 로고    scopus 로고
    • Montvale, NJ: Thomson PDR
    • Red Book. 2006 ed. Montvale, NJ: Thomson PDR; 2006: 678.
    • (2006) Red Book. 2006 Ed. , pp. 678
  • 69
    • 0033917664 scopus 로고    scopus 로고
    • The use of human antithrombin III concentrate for treatment of heparin resistance during cardiopulmonary bypass
    • Brown ME, Gallagher JM, Armitage JM. The use of antithrombin III concentrate for treatment of heparin resistance during cardiopulmonary bypass. J Extra-Corporeal Tech 2000; 32: 75-78. (Pubitemid 30432595)
    • (2000) Journal of Extra-Corporeal Technology , vol.32 , Issue.2 , pp. 75-78
    • Brown, M.E.1    Gallagher, J.M.2    Armitage, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.