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The asymmetric diastereomer 13b was also converted to the tetraacetal 14; however, a significantly lower yield (7%) was obtained (under unoptimized conditions).
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The asymmetric diastereomer 13b was also converted to the tetraacetal 14; however, a significantly lower yield (7%) was obtained (under unoptimized conditions).
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53
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66149192324
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Due to solubility problems of the larger oligoacetals, work-up is very difficult and may be the reason for the lower yields of 17 and 20.
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Due to solubility problems of the larger oligoacetals, work-up is very difficult and may be the reason for the lower yields of 17 and 20.
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54
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19444375335
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The diffractometer was equipped with a copper rotating anode (17) or a molybdenum micro source (14). Diffraction data of structure 14 also allowed an invariom refinement which led to significant improvements in the figures of merit and the physical significance of the anisotropic displacement parameters (ADPs). For the method of invariom refinement see: Dittrich, B.; Hübschle, C. B.; Messerschmidt, M.; Kalinowski, R.; Girnt, D.; Luger, P. Acta Crystallogr. 2005, A61, 314-320.
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The diffractometer was equipped with a copper rotating anode (17) or a molybdenum micro source (14). Diffraction data of structure 14 also allowed an invariom refinement which led to significant improvements in the figures of merit and the physical significance of the anisotropic displacement parameters (ADPs). For the method of invariom refinement see: Dittrich, B.; Hübschle, C. B.; Messerschmidt, M.; Kalinowski, R.; Girnt, D.; Luger, P. Acta Crystallogr. 2005, A61, 314-320.
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Cif files have also been deposited with the Cambridge Crystallographic Data Centre as supplementary publication no. CCDC-725973 (12a), CCDC-720562 (14), and CCDC-720971 (17). Copies can be obtained via email: data-request
-
Cif files have also been deposited with the Cambridge Crystallographic Data Centre as "supplementary publication no. CCDC-725973 (12a), CCDC-720562 (14), and CCDC-720971 (17)". Copies can be obtained via email: data-request
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