Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity

Journal of Cellular Biochemistry

Volumn 107, Issue 1, 2009, Pages 179-188

  Zeng, Yu ^a   Kulkarni, Prakash ^a   Inoue, Takahiro ^a   Getzenberg, Robert H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chemotherapy; Cold shock proteins; Prostate cancer

Indexed keywords

COLD INDUCIBLE RNA BINDING PROTEIN; COLD SHOCK PROTEIN; HEAT SHOCK PROTEIN; RNA BINDING MOTIF PROTEIN 3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER GROWTH; CELL SURVIVAL; CHEMOSENSITIVITY; CONTROLLED STUDY; DNA REPAIR; DOWN REGULATION; HEAT TREATMENT; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; DOWN-REGULATION; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HOT TEMPERATURE; HUMANS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; TRANSFECTION;

EID: 66149175050     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22114     Document Type: Article

References (33)

1. Al-Fageeh MB, Smales CM. 2006. Control and regulation of the cellular responses to cold shock: The responses in yeast and mammalian systems. Biochem J 397:247-259.
2. Berezney R, Mortillaro MJ, Ma H, Wei X, Samarabandu J. 1995. The nuclear matrix: A structural milieu for genomic function. Int Rev Cytol 162A:1-65.
3. Coffey DS, Getzenberg RH, DeWeese TL. 2006. Hyperthermic biology and cancer therapies: A hypothesis for the "Lance Armstrong effect". JAMA 296:445-448.
4. Danno S, Nishiyama H, Higashitsuji H, Yokoi H, Xue JH, Itoh K, Matsuda T, Fujita J. 1997. Increased transcript level of RBM3, a member of the glycine-rich RNA-binding protein family, in human cells in response to cold stress. Biochem Biophys Res Commun 236:804-807.
5. De Leeuw F, Zhang T, Wauquier C, Huez G, Kruys V, Gueydan C. 2007. The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressor. Exp Cell Res 313:4130-4144.
6. Dewhirst MW, Vujaskovic Z, Jones E, Thrall D. 2005. Re-setting the biologic rationale for thermal therapy. Int J Hyperthermia 21:779-790.
7. Didelot C, Lanneau D, Brunet M, Joly AL, De Thonel A, Chiosis G, Garrido C. 2007. Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins. Curr Med Chem 14:2839-2847.
8. Ferguson MW, Joanen T. 1982. Temperature of egg incubation determines sex in Alligator mississippiensis. Nature 296:850-853.
9. Garner E, Raj K. 2008. Protective mechanisms of p53-p21-pRb proteins against DNA damage-induced cell death. Cell Cycle 7:277-282.
10. Garrido C, Brunet M, Didelot C, Zermati Y, Schmitt E, Kroemer G. 2006. Heat shock proteins 27 and 70: Anti-apoptotic proteins with tumorigenic properties. Cell Cycle 5:2592-2601.
11. Getzenberg RH, Konety BR, Oeler TA, Quigley MM, Hakam A, Becich MJ, Bahnson RR. 1996. Bladder cancer-associated nuclear matrix proteins. Cancer Res 56:1690-1694.
12. Guan K, Nayernia K, Maier LS, Wagner S, Dressel R, Lee JH, Nolte J, Wolf F, Li M, Engel W, Hasenfuss G. 2006. Pluripotency of spermatogonial stem cells from adult mouse testis. Nature 440:1199-1203.
13. Inoue T, Leman ES, Yeater DB, Getzenberg RH. 2008. The potential role of purine-rich element binding protein (PUR) alpha as a novel treatment target for hormone-refractory prostate cancer. Prostate 68:1048-1056.
14. Kamada M, So A, Muramaki M, Rocchi P, Beraldi E, Gleave M. 2007. Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells. Mol Cancer Ther 6:299-308.
15. Lane DP. 1992. Cancer. p53, guardian of the genome. Nature 358:15-16.
16. Lepock JR, Frey HE, Heynen ML, Senisterra GA, Warters RL. 2001. The nuclear matrix is a thermolabile cellular structure. Cell Stress Chaperones 6:136-147.
17. Mujoo K, Watanabe M, Khokhar AR, Siddik ZH. 2005. Increased sensitivity of a metastatic model of prostate cancer to a novel tetravalent platinum analog. Prostate 62:91-100.
18. Myerson RJ, Roti Roti JL, Moros EG, Straube WL, Xu M. 2004. Modelling heat-induced radiosensitization: Clinical implications. Int J Hyperthermia 20:201-212.
19. Nishiyama H, Danno S, Kaneko Y, Itoh K, Yokoi H, Fukumoto M, Okuno H, Millan JL, Matsuda T, Yoshida O, Fujita J. 1998. Decreased expression of cold-inducible RNA-binding protein (CIRP) in male germ cells at elevated temperature. Am J Pathol 152:289-296.
20. O'Connor PM, Jackman J, Bae I, Myers TG, Fan S, Mutoh M, Scudiero DA, Monks A, Sausville EA, Weinstein JN, Friend S, Fornace AJ, Jr., Kohn KW. 1997. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res 57:4285-4300.
21. Oesterreich S, Lee AV, Sullivan TM, Samuel SK, Davie JR, Fuqua SA. 1997. Novel nuclear matrix protein HET binds to and influences activity of the HSP27 promoter in human breast cancer cells. J Cell Biochem 67:275-286.
22. Pederson T. 2000. Half a century of "the nuclear matrix". Mol Biol Cell 11:799-805. (Pubitemid 30159302)
23. Plesca D, Mazumder S, Almasan A. 2008. DNA damage response and apoptosis. Methods Enzymol 446:107-122.
24. Rocchi P, Jugpal P, So A, Sinneman S, Ettinger S, Fazli L, Nelson C, Gleave M. 2006. Small interference RNA targeting heat-shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase-3 activation in vitro. BJU Int 98:1082-1089.
25. Roti Roti JL. 2008. Cellular responses to hyperthermia (40-46 degrees C): Cell killing and molecular events. Int J Hyperthermia 24:3-15.
26. Roti Roti JL, Kampinga HH, Malyapa RS, Wright WD, vanderWaal RP, Xu M. 1998. Nuclear matrix as a target for hyperthermic killing of cancer cells. Cell Stress Chaperones 3:245-255.
27. Shamovsky I, Nudler E. 2008. New insights into the mechanism of heat shock response activation. Cell Mol Life Sci 65:855-861.
28. Shevchenko A, Wilm M, Vorm O, Mann M. 1996. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68:850-858.
29. Sureban SM, Ramalingam S, Natarajan G, May R, Subramaniam D, Bishnupuri KS, Morrison AR, Dieckgraefe BK, Brackett DJ, Postier RG, Houchen CW, Anant S. 2008. Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe. Oncogene 27:4544-4556.
30. Sutherland LC, Rintala-Maki ND, White RD, Morin CD. 2005. RNA binding motif (RBM) proteins: A novel family of apoptosis modulators? J Cell Biochem 94:5-24.
31. Weinberg RA. 1991. Tumor suppressor genes. Science 254:1138-1146.
32. Yang C, Carrier F. 2001. The UV-inducible RNA-binding protein A18 (A18 hnRNP) plays a protective role in the genotoxic stress response. J Biol Chem 276:47277-47284.
33. Zhao ZG, Ma QZ, Xu CX. 2004. Abrogation of heat-shock protein (HSP)70 expression induced cell growth inhibition and apoptosis in human androgen-independent prostate cancer cell line PC-3m. Asian J Androl 6:319-324.