The δ2 glutamate-like receptor undergoes similar conformational changes as other ionotropic glutamate receptors

Journal of Neuroscience

Volumn 29, Issue 21, 2009, Pages 6767-6768

  MacLean, David M ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR DELTA2; IONOTROPIC RECEPTOR; SERINE; UNCLASSIFIED DRUG; GLUTAMATE RECEPTOR DELTA 2; GLUTAMIC ACID;

AMINO ACID SEQUENCE; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; LONG TERM DEPRESSION; MUTATION; NERVE ENDING; NOTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STABILITY; ANIMAL; CHANNEL GATING; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

ANIMALS; GLUTAMIC ACID; ION CHANNEL GATING; RECEPTORS, GLUTAMATE;

EID: 66149168578     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1456-09.2009     Document Type: Note

References (11)

1. Abele R, Lampinen M, Keinänen K, Madden DR (1998) Disulfide bonding and cysteine accessibility in the alpha-amino-3-hydroxy-5-methylisoxazole-4- propionic acid receptor subunit GluRD. Implications for redox modulation of glutamate receptors. J Biol Chem 273:25132-25138. (Pubitemid 28443272)
2. 2+ modulation of the NMDA receptor. J Neurosci 21:392-400.
3. Hansen KB, Naur P, Kurtkaya NL, Kristensen AS, Gajhede M, Kastrup JS, Traynelis SF (2009) Modulation of the dimer interface at ionotropic glutamate-like receptor δ2 by D-serine and extracellular calcium. J Neurosci 29:907-917.
4. Kakegawa W, Kohda K, Yuzaki M (2007) The delta2 'ionotropic' glutamate receptor functions as a non-ionotropic receptor to control cerebellar synaptic plasticity. J Physiol 584:89-96. (Pubitemid 47500542)
5. Kuroyanagi T, Yokoyama M, Hirano T (2009) Postsynaptic glutamate receptor δ familiy contributes to presynaptic terminal differentiation and establishment of synaptic transmission. Proc Natl Acad Sci U S A 106:4912-4916.
6. Naur P, Hansen KB, Kristensen AS, Dravid SM, Pickering DS, Olsen L, Vestergaard B, Egebjerg J, Gajhede M, Traynelis SF, Kastrup JS (2007) Ionotropic glutamate-like receptor delta2 binds d-ser and glycine. Proc Natl Acad Sci U S A 104:14116-14121. (Pubitemid 350003344)
7. Ruiz A, Sachidhanandam S, Utvik JK, Coussen F, Mulle C (2005) Distinct subunits in heteromeric kainate receptors mediate ionotropic and metabotropic function at hippocampal mossy fiber synapses. J Neurosci 25:11710-11718. (Pubitemid 43098463)
8. Schmid SM, Hollmann M (2008) To gate or not to gate: are the delta subunits in the glutamate receptor family functional ion channels? Mol Neurobiol 37:126-141.
9. Taverna F, Xiong ZG, Brandes L, Roder JC, Salter MW, MacDonald JF (2000) The lurcher mutation of an alpha-amino-3-hydroxy-5-methyl-isoxazolepropionic acid receptor subunit enhances the potency of glutamate and converts and antagonist to an agoinst. J Biol Chem 275:8475-8479. (Pubitemid 30180193)
10. 2+. J Neurosci 20:5973-5980.
11. Yuzaki M (2005) Transgenic rescue for characterizing orphan receptors: a review of δ2 glutamate receptor. Transgenic Res 14:117-121. (Pubitemid 40747891)