Unprecedented, low cytotoxicity of spongelike calcium phosphate/poly(ethylene imine) hydrogel composites

Macromolecular Bioscience

Volumn 9, Issue 2, 2009, Pages 179-186

  Shkilnyy, Andriy ^a,b   Gräf, Ralph ^a   Hiebl, Bernhard ^c,d   Neffe, Axel T ^c,d   Friedrich, Alwin ^a   Hartmann, Jürgen ^b   Taubert, Andreas ^a,b  

^a UNIVERSITY OF POTSDAM   (Germany)

^b MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^c INSTITUTE OF MATERIALS RESEARCH   (Germany)

^d Berlin Brandenburg Center for Regenerative Therapies   (Germany)

Author keywords

Composites; Hydrogels; MineralsPoly(ethylene imine)

Indexed keywords

BIOMEDICAL APPLICATIONS; BRUSHITE; CHEMICAL COMPOSITIONS; COMPOSITES; CROSSLINKED; CYTOTOXICITY TEST; DEGRADATION PRODUCTS; DICTYOSTELIUM DISCOIDEUM; HYDROGEL COMPOSITES; MINERALSPOLY(ETHYLENE IMINE); NUCLEATION AND GROWTH;

CALCIUM; CALCIUM ALLOYS; CALCIUM PHOSPHATE; COMPOSITE MICROMECHANICS; CROSSLINKING; DEGRADATION; ETHYLENE; HYDROXYAPATITE; NITROGEN COMPOUNDS;

HYDROGELS;

CALCIUM PHOSPHATE; CALCIUM PHOSPHATE DIBASIC; HYDROXYAPATITE; POLYETHYLENEIMINE;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DICTYOSTELIUM DISCOIDEUM; HYDROGEL; MINERALIZATION; NONHUMAN;

ANIMALS; BODY FLUIDS; CALCIUM PHOSPHATES; CELL DEATH; CROSS-LINKING REAGENTS; DICTYOSTELIUM; HYDROGEL; MICROSCOPY, ELECTRON, SCANNING; POLYETHYLENEIMINE; PORIFERA; PRECIPITATION; SPECTROPHOTOMETRY, INFRARED; THERMOGRAVIMETRY; X-RAY DIFFRACTION;

DICTYOSTELIUM DISCOIDEUM;

EID: 66149127762     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.200800266     Document Type: Article

References (43)

1. Z. Amjad, Ed., "Calcium Phosphates in Biological and Industrial Systems", Kluwer, Dordrecht, The Netherlands 1998.
2. M. Bohner, U. Gbureck, J. E. Barralet, Biomaterials 2005, 26, 6423.
3. G. Falini, M. Gazzano, A. Ripamonti, Adv. Mater. 1994, 6, 46.
4. E. Bertoni, A. Bigi, G. Falini, S. Panzavolta, N. Roveri, J. Mater. Chem. 1999, 9, 779.
5. A. Peytcheva, H. Cölfen, H. Schnablegger, M. Antonietti, Colloid Polym. Sci. 2002, 280, 218.
6. S. Schweizer, A. Taubert, Macromol. Biosci. 2007, 7, 1085.
7. H. Colfen, S. Mann, Angew. Chem. Int. Ed. Engl. 2003, 42, 2350.
8. M. Iijima, Y. Moriwaki, J. Cryst. Growth 1991, 112, 571.
9. M. Iijima, Y. Moriwaki, J. Cryst. Growth 1998, 194, 125.
10. M. Iijima, Y. Moriwaki, R. Yamaguchi, Y. Kuboki, Connect. Tissue Res. 1997, 36, 73.
11. S. Busch, H. Dolhaine, A. DuChesne, S. Heinz, O. Hochrein, F. Laeri, O. Podebrad, U. Vietze, T. Weiland, R. Kniep, Eur. J. Inorg. Chem. 1999, 10, 1643.
12. R. Kniep, S. Busch, Angew. Chem. Int. Ed. Engl. 1996, 35, 2624.
13. P. Simon, D. Zahn, H. Lichte, R. Kniep, Angew. Chem. Int. Ed. 2006, 45, 1911.
14. J. Song, V. Malathong, C. R. Bertozzi, J. Am. Chem. Soc. 2005, 127, 3366.
15. J. Song, E. Saiz, C. R. Bertozzi, J. Am. Chem. Soc. 2003, 125, 1236.
16. S. Busch, U. Schwarz, R. Kniep, Chem. Mater. 2001, 13, 3260.
17. K. Gobel, P. Simon, J. Buder, H. Tlatlik, R. Kniep, J. Mater. Chem. 2004, 14.
18. H. Tlatlik, P. Simon, A. Kawska, D. Zahn, R. Kniep, Angew. Chem. Int. Ed. 2006, 45, 1905.
19. M. Iijima, C. Du, C. Abbott, Y. Doi, J. Moradian-Oldak, Eur. J. Oral Sci. 2006, 114, 304.
20. M. Iijima, K. Iijima, Y. Moriwaki, Y. Kuboki, J. Cryst. Growth 1994, 140, 91.
21. M. Iijima, J. Moradian-Oldak, J. Mater. Chem. 2004, 14, 2189.
22. M. Iijima, Y. Moriwaki, Y. Kuboki, Curr. Top. Cryst. Growth Res. 1995, 2, 1.
23. M. Iijima, Y. Moriwaki, Y. Kuboki, Connect. Tissue Res. 1997, 36, 51.
24. M. Iijima, Y. Moriwaki, Y. Kuboki, Connect. Tissue Res. 1998, 38, 171.
25. A. Taubert, E. Furrer, W. Meier, Chem. Commun. 2004, 2170.
26. A. Shkilnyy, A. Friedrich, B. Tiersch, S. Schöne, M. Fechner, J. Koetz, C.-W. Schläpfer, A. Taubert, Langmuir 2008, 24, 2102.
27. M. Rehberg, R. Gräf, Mol. Biol. Cell 2002, 13, 2301.
28. R. Gräf, Methods Cell Biol. 2001, 67, 337.
29. A. Osaka, Y. Miura, K. Takeuchi, M. Asada, K. Takahashi, J. Mater. Sci.: Mater. Med. 1991, 2, 51.
30. S. Cazalbou, C. Combes, D. Eichert, C. Rey, J. Mater. Chem. 2004, 14, 2148.
31. S. Busch, U. Schwarz, R. Kniep, Adv. Funct. Mater. 2003, 13, 189.
32. P. Simon, U. Schwarz, R. Kniep, J. Mater. Chem. 2005, 15, 4992.
33. P. Simon, W. Carrillo-Cabrera, P. Formanek, C. Gobel, D. Geiger, R. Ramlau, H. Tlatlik, J. Buder, R. Kniep, J. Mater. Chem. 2004, 14, 2218.
34. Z. Amjad, Langmuir 1989, 5, 1222.
35. Z. Amjad, Phosphorus Res. Bull. 1997, 7, 45.
36. E. Kokufuta, H. Suzuki, R. Yoshida, K. Yamada, M. Hirata, F. Kaneko, Langmuir 1998, 14, 788.
37. V. Ball, M. Michel, F. Boulmedais, J. Hemmerle, Y. Haikel, P. Schaaf, J. C. Voegel, Cryst. Growth Design 2006, 6, 327.
38. P. A. Ngankam, P. Lavalle, J. C. Voegel, L. Szyk, G. Decher, P. Schaaf, F. J. G. Cuisinier, J. Am. Chem. Soc. 2000, 122, 8998.
39. X. Zainuddin, D. J. T. Hill, T. V. Chirila, A. K. Whittaker, A. Kemp, Biomacromolecules 2006, 7, 1758.
40. S. Peng, S. Kumar, N. H. Voelcker, E. Szili, R. S. C. Smart, H. J. Griesser, J. Biomed. Mater. Res. A 2006, 76, 347.
41. M. Michel, Y. Arntz, G. Fleith, J. Toquant, Y. Haikel, J.-C. Voegel, P. Schaaf, V. Ball, Langmuir 2006, 22, 2358.
42. C. Combes, C. Rey, Biomaterials 2002, 23, 2817.
43. R. S. B. Williams, K. Boeckeler, R. Gräf, A. Müller-Taubenberger, Z. Li, R. R. Isberg, D. Wessels, D. R. Soll, H. Alexander, S. Alexander, Trends Mol. Med. 2006, 12, 415.