Cardioprotective actions of ascorbic acid during isoproterenol-induced acute myocardial infarction in rats

Pharmacology

Volumn 84, Issue 1, 2009, Pages 29-37

  Buttros, Juliana B ^a   Bergamaschi, Cassia T ^a   Ribeiro, Daniel A ^a   Fracalossi, Ana C C ^a   Campos, Ruy R ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antioxidant; Baroreceptor reflex; Ischemia; Oxidative stress; Vitamin C

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOPRENALINE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BRADYCARDIA; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; HEART MUSCLE INJURY; HEART PROTECTION; MALE; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RAT; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; BLOOD PRESSURE; CARDIOTONIC AGENTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ISOPROTERENOL; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; NITRIC OXIDE SYNTHASE TYPE II; NITROPRUSSIDE; PHENYLEPHRINE; RATS; RATS, WISTAR;

EID: 66149091535     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000222245     Document Type: Article

References (54)

1. Dhalla NS, Temsah RM, Netticadan T: Role of oxidative stress in cardiovascular diseases. J Hypertens 2000; 18: 655-673. (Pubitemid 30406736)
2. Petrich ER, Schanne OF, Zumino AP: Electrophysiological responses to ischemia and reperfusion; in Karmazyn M (ed): Myocardial Ischemia: Mechanism, Reperfusion, Protection. Basel, Birkhauser, 1996, pp 115-133.
3. Kumar SHS, Anandan R: Biochemical studies on the cardioprotective effect of glutamine on tissue antioxidant defense system in isoprenaline-induced myocardial infarction in rats. J Clin Biochem Nutr 2007; 40: 49-55. (Pubitemid 46449687)
4. Rona G: Catecholamine cardiotoxicity. J Mol Cell Cardiol 1995; 17: 291-300.
5. Chagoya de Sanchez V, Hernandez-Munoz R, Lopez-Barrera F, Yanez L, Vidrio S, Suarez J, Cota-Garza MD, Aranda-Fraustro A, Cruz D: Sequential changes of energy metabolism and mitochondrial function in myocardial infarction induced by isoproterenol in rats: a long-term and integrative study. Can J Physiol Pharmacol 1997; 75: 1300-1311. (Pubitemid 28130369)
6. Ithayarasi AP, Devi CSS: Effect of alpha tochopherol on lipid peroxidation in isoproterenol induced myocardial infarction in rats. Indian J Physiol Pharmacol 1997; 41: 369-376. (Pubitemid 27507825)
7. Kakreja RC, Hess ML: The oxygen free radical system from equations through membrane-protein interactions to cardiovascular injury and protection. Cardiovasc Res 1992; 26: 641-655.
8. Oliveira-Sales EB, Dugaich APC, Carillo BA, De Abreu NP, Boim MA, Martins PJF, et al: Oxidative stress contributes to renovascular hypertension. Am J Hypertens 2008; 21: 98-104.
9. Farvin KHS, Anandan R, Kumar SHS, Shiny KS, Sankar TV, Thankappan TK: Effect of squalene on tissue defence system in isoproterenol-induced myocardial infarction in rats. Pharmacol Res 2004; 50: 231-236. (Pubitemid 38844475)
10. Geng B, Chang L, Pan C, Qi Y, Zhao J, Pang Y, et al: Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol. Biochem Biophys Res Commun 2004; 318: 756-763. (Pubitemid 38624219)
11. Ciaccio M, Valenza M, Tesoriere L, Bongiorno A, Albiero R, Livrea MA: Vitamin A inhibits doxorubicin induced membrane lipid peroxidation in rat tissues in vivo. Arch Biochem Biophys 1993; 302: 103-108. (Pubitemid 23212621)
12. Walker AF: Of hearts and herbs. Biologist 1996; 43: 177-180.
13. Bendich A, Machlin LJ, Scandurra O: The antioxidant role of vitamin C. Adv Free Radic Biol Med 1986; 2: 419-444.
14. Dhalla NS, Temsah RM, Netticadan T: Role of oxidative stress in cardiovascular diseases. J Hypertens 2000; 18: 655-673. (Pubitemid 30406736)
15. Li C, Jackson RM: Reactive species mechanisms of cellular hypoxia-reoxygenation injury. Am J Physiol Cell Physiol 2002; 282: C227-C241. (Pubitemid 34663181)
16. Yogeeta SK, Gnanapragasam A, Kumar SS, Sathivel RSA, Devaki T: Synergistic interactions of ferulic acid with ascorbic acid: its cardioprotective role during isoproterenol induced myocardial infarction in rats. Mol Cell Biochem 2006; 283: 139-146.
17. De Ferrari GM, Vanoli E, Stramba-Badiale M, Hull SS Jr, Foreman RD, Schwartz PJ: Vagal reflexes and survival during acute myocardial ischemia in conscious dogs with healed myocardial infarction. Am J Physiol 1991; 261:H63-H69.
18. Matsusaka H, Ide T, Matsushima S, Ikeuchi M, Kubota T, Sunagawa K, et al: Targeted deletion of p53 prevents cardiac rupture after myocardial infarction in mice. Cardiovasc Res 2006; 70: 457-465.
19. May PM, May E: Twenty years of p53 research: structural and functional aspects of the p53 protein. Oncogene 1999; 18: 7621-7636.
20. Bullock AN, Fersht AR: Rescuing the function of mutant p53. Nat Rev Cancer 2001; 1: 68-76.
21. Levine AJ: P53, the cellular gatekeeper for growth and division. Cell 1997; 88: 323-331.
22. Fukumura D, Kashiwagi S, Jain RK: The role of nitric oxide in tumour progression. Nat Rev Cancer 2006; 6: 521-534. (Pubitemid 43980541)
23. Knowles RG, Moncada S: Nitric oxide synthases in mammals. Biochem J 1994; 298: 249-258.
24. Beevi SS, Rasheed AM, Geetha A: Evaluation of oxidative stress and nitric oxide levels in patients with oral cavity cancer. Jpn J Clin Oncol 2004; 34: 379-385.
25. Nathan C, Xie QW: Nitric oxide synthases, roles, tolls, and controls. Cell 1994; 78: 915-918. (Pubitemid 24292319)
26. Kargman S, Charleson S, Cartwright M, Frank J, Riendeau D, Mancini J, et al: Characterization of prostaglandin G/H Synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts. Gastroenterology 1996; 111: 445-454. (Pubitemid 26256734)
27. Jackson TS, Xu A, Vita JA, Keaney JF Jr: Ascorbate prevents the interaction of superoxide and nitric oxide only at very high physiological concentrations. Circ Res 1998; 83: 916-922. (Pubitemid 28503080)
28. Farah VM, Moreira ED, Irigoyen MC, Krieger EM: Baroreflex depression persists in the early phase after hypertension reversal. Am J Physiol Regul Integr Comp Physiol 2001; 280:R1620-R1626. (Pubitemid 32552446)
29. Acikel M, Buyykokuroglu ME, Erdogan F, Aksoy H, Bozkurt E, Senocak H: Protective effects of dantrolene against myocardial injury induced by isoproterenol in rats: biochemical and histological findings. Int J Cardiol 2005; 98: 389-394. (Pubitemid 40247926)
30. Matsumoto MA, De Oliveira A, Ribeiro Junior PD, Nary Filho H, Ribeiro DA: Shortterm administration of non-selective and selective COX-2 NSAIDs do not interfere with bone repair in rats. J Mol Histol 2008; 39: 381-387.
31. Brodde OE: β1- and β2 Adrenoceptors in the human heart: properties, function, and alteration in chronic heart failure. Pharmacol Rev 1991; 43: 203-242.
32. Yeager JC, Iams SG: The hemodynamics of isoproterenol-induced cardiac failure in rats. Circ Shock 1981; 8: 151-163. (Pubitemid 11077993)
33. Bloom S, Davis DL: Calcium as a mediator of isoproterenol-induced myocardial necrosis. Am J Pathol 1972; 69: 459-470.
34. Singal PK, Beamish RE, Dhalla NS: Potential oxidative pathways of catecholamines in the formation of lipid peroxides and genesis of heart disease. Adv Exp Med Biol 1983; 161: 391-440.
35. Lown B, Verrier RL: Neural activity and ventricular fibrillation. N Engl J Med 1976; 294: 1165-1170.
36. Piccirillo G, Nocco M, Moise A, Lionetti M, Naso C, di Carlo S, Marigliano V: Influence of vitamin C on baroreflex sensitivity in chronic heart failure. Hypertension 2003; 41: 1240-1245. (Pubitemid 36706072)
37. Billman GE, Schwartz PJ, Stone HL: Baroreceptor reflex control of heart rate: a predictor of sudden cardiac death. Circulation 1982; 66: 874-880. (Pubitemid 12015075)
38. La Rovere MT, Bigger JT Jr, Marcus FI, Mortara A, Schwartz PJ: Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes after Myocardial Infarction) Investigators. Lancet 1998; 351: 478-484.
39. La Rovere MT, Pinna GD, Hohnloser SH, Markus FI, Mortara A, Nohara R, Bigger T Jr, Camm AJ, Schwartz PJ: Baroreflex sensitivity and heart rate variability in the identification of patients at risk for life-threatening arrhythmias: implications for clinical trials. Circulation 2001; 103: 2072-2077. (Pubitemid 32373010)
40. Chapleau MW, Li Z, Meyrelles SS, Ma X, Abboud FM: Mechanisms determining sensitivity of baroreceptor afferents in health and disease. Ann NY Acad Sci 2001; 940: 1-19. (Pubitemid 32623379)
41. Lakatta EG, Levy D: Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises. I. Aging arteries: a 'set up' for vascular disease. Circulation 2003; 107: 139-146.
42. Ebert TJ, Morgan BJ, Barney JA, Denahan T, Smith JJ: Effects of aging on baroreflex regulation of sympathetic activity in humans. Am J Physiol Heart Circ Physiol 1992; 263: H798-H803.
43. Gribbin B, Pickering TG, Sleight P, Peto R: Effect of age and high blood pressure on baroreflex sensitivity in man. Circ Res 1971; 29: 424-431.
44. Monahan KD, Dinenno FA, Tanaka H, Clevenger CM, DeSouza CA, Seals DR: Regular aerobic exercise modulates age-associated declines in cardiovagal baroreflex sensitivity in healthy men. J Physiol 2000; 529: 263-271.
45. Hamilton CA, Brosnan MJ, McIntyre M, Graham D, Dominiczak AF: Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. Hypertension 2001; 37: 529-534. (Pubitemid 32199023)
46. Sun F, Hamagawa E, Tsutsui C, Sakaguchi N, Kakuta Y, Tokumaru S, Kojo S: Evaluation of oxidative stress during apoptosis and necrosis caused by D -galactosamine in rat liver. Biochem Pharmacol 2003; 65: 101-107. (Pubitemid 35447844)
47. Landmesser U, Merten R, Spiekermann S, Buttner K, Drexler H, Hornig B: Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase. Circulation 2002; 106: 3073-3078. (Pubitemid 35440291)
48. Monahan KD, Eskurza I, Seals DR: Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men. Am J Physiol Heart Circ Physiol 2004; 286:H2113-H2117. (Pubitemid 38685224)
49. Rossig L, Hoffmann J, Hugel B, Mallat Z, Haase A, Freyssinet JM, et al: Vitamin C inhibits endothelial cell apoptosis in congestive heart failure. Circulation 2001; 104: 2182-2187. (Pubitemid 33043297)
50. Zhou B, Wu LJ, Li LH, Tashiro S, Onodera S, Uchiumi F, et al: Silibinin protects against isoproterenol-induced rat cardiac myocyte injury through mitochondrial pathway after up-regulation of SIRT1. J Pharmacol Sci 2006; 102: 387-395. (Pubitemid 44954598)
51. Díaz-Muñoz M, Alvarez-Pérez MA, Yáñez L, Vidrio S, Martínez L, Rosas G, Yáñez M, Ramírez S, de Sánchez VC: Correlation between oxidative stress and alteration of intracellular calcium handling in isoproterenol-induced myocardial infarction. Mol Cell Biochem 2006; 289: 125-136.
52. Li D, Qu Y, Tao L, Liu H, Hu A, Gao F, et al: Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury. J Surg Res 2006; 131: 64-72. (Pubitemid 43227585)
53. Zhang J, Knapton A, Lipshultz SE, Weaver JL, Herman EH: Isoproterenol-induced cardiotoxicity in Sprague-Dawley rats: correlation of reversible and irreversible myocardial injury with release of cardiac troponin T and roles of iNOS in myocardial injury. Toxicol Pathol 2008; 36: 277-278.
54. Ye Y, Martinez JD, Perez-Polo RJ, Lin Y, Uretsky BF, Birnbaum Y: The role of eNOS, iNOS, and NF-kappaB in upregulation and activation of cyclooxygenase-2 and infarct size reduction by atorvastatin. Am J Physiol Heart Circ Physiol 2008; 295:H343-H351.