Specific antibodies to diisocyanate and work-related respiratory symptoms in apprentice car-painters

Occupational and Environmental Medicine

Volumn 66, Issue 4, 2009, Pages 227-234

  Dragos, M ^a   Jones, M ^b   Malo, J L ^a   Ghezzo, H ^a   Gautrin, D ^a  

^a HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; HEXAMETHYLENE DIISOCYANATE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G4; ISOCYANIC ACID DERIVATIVE;

ADULT; ARTICLE; COHORT ANALYSIS; FEMALE; HIGH RISK POPULATION; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL ASTHMA; OCCUPATIONAL EXPOSURE; OCCUPATIONAL LUNG DISEASE; PAINTER; PRIORITY JOURNAL; PROSPECTIVE STUDY; RHINOCONJUNCTIVITIS; SYMPTOMATOLOGY;

ADOLESCENT; ADULT; AIR POLLUTANTS, OCCUPATIONAL; ANTIBODIES, ANTI-IDIOTYPIC; AUTOMOBILES; CANADA; COHORT STUDIES; CYANATES; FEMALE; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INSERVICE TRAINING; MALE; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; PAINT; PROSPECTIVE STUDIES; QUESTIONNAIRES; RESPIRATORY TRACT DISEASES; YOUNG ADULT;

EID: 66149091418     PISSN: 13510711     EISSN: 14707926     Source Type: Journal    
DOI: 10.1136/oem.2007.038125     Document Type: Article

References (31)

1. McDonald JC, Keynes HL, Meredith SK. Reported incidence of occupational asthma in the United Kingdom, 1989-97. Occup Environ Med 2000;57:823-9.
2. Becklake MR, Chan-Yeung M, Malo JL. Epidemiological approaches in occupational asthma. In: Bernstein IL, Chan-Yeung M, Malo JL, et al, eds. Asthma in the workplace. 3rd ed. New York: Taylor & Francis, 2006:37-85.
3. 3. Seguin P, Allard A, Cartier A, et al. Prevalence of occupational asthma in spray painters exposed to several types of isocyanates, including polymethylene polyphenylisocyanates. J Occup Med 1987;29:340-344 (Pubitemid 17086932)
4. 4. Ott MG, Diller WF, Jolly AT. Respiratory effects of toluene diisocyanate in the workplace: a discussion of exposure-response relationships. Crit Rev Toxicol 2003;33:1-59. (Pubitemid 36187393)
5. Wisnewski A, Redlich CA, Mapp CE, et al. Polyisocyanates and their prepolymers. In: Bernstein IL, Chan-Yeung M, Malo JL, et al, eds. Asthma in the workplace. 3rd ed. New York: Taylor & Francis, 2006:481-504.
6. 6. Tee RD, Cullinan P, Welch J, et al. Specific IgE to isocyanates: a useful diagnostic role in occupational asthma. J Allergy Clin Immunol 1998;101:709-715 (Pubitemid 28228317)
7. 7. Cartier A, Grammer L, Malo JL, et al. Specific serum antibodies against isocyanates: association with occupational asthma. J Allergy Clin Immunol 1989;84:507-514 (Pubitemid 19266747)
8. 8. Gautrin D, Infante-Rivard C, Ghezzo H, et al. Incidence and host determinants of probable occupational asthma in apprentices exposed to laboratory animals. Am J Respir Crit Care Med 2001;163:899-904. (Pubitemid 32275861)
9. 9. Gautrin D, Ghezzo H, Infante-Rivard C, et al. Natural history of sensitization, symptoms and diseases in apprentices exposed to laboratory animals. Eur Respir J 2001;17:904-908 (Pubitemid 32600337)
10. Burney PG, Laitinen LA, Perdrizet S, et al. Validity and repeatibility of the IUATLD (1984) Bronchial Symptoms Questionnaire: an international comparison. Eur Respir J 1989;2:940-945
11. American Thoracic Society. Standardization of spirometry. Am J Respir Crit Care Med 1995;152:1107-1136
12. Sterk PJ, Fabbri LM, Quanjer PH, et al. Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Report working party standardization of lung function tests European Community for Steel and Coal. Official statement of the European Respiratory Society. Eur Respir J 1993;6(suppl 16):53-83.
13. Knudson RJ, Lebowitz MD, Holberg CJ, etal. Changes in the normal maximal expiratory flow-volume curve with growth and aging. Am Rev Respir Dis 1983;127:725-734
14. Malo JL, Pineau L, Cartier A, et al. Reference values of the provocative concentrations of methacholine that cause 6% and 20% changes in forced expiratory volume in one second in a normal population. Am Rev Respir Dis 1983;128:8-11.
15. Jones M, Cullinan P, Durham S, et al. Cellular aspects of occupational asthma: immunologic studies in isocyanate exposed subjects. London: Health and Safety Executive, Research report 122, 2003.
16. 16. Jeal H, Draper A, Harris J, et al. Modified Th2 responses at high-dose exposures to allergen: using an occupational model. Am J Respir Crit Care Med 2006;174:21-25 (Pubitemid 43955240)
17. Lesage J, Perrault G. Environmental monitoring of chemical agents. In: Bernstein IL, Chan-Yeung M, Malo JL, et al, eds. Asthma in the workplace. 3rd ed. New York: Taylor & Francis, 2006:297-318.
18. Koenker R. Quantile regression. Cambridge, UK: Cambridge University Press, 2005
19. R Development Core team. R: a language and environmant for statistical computing. Vienna, Austria: R Foundation for Statistical Computing. http: //www.R-project.org.
20. Toelle BG, Peat JK, Salome CM, et al. Toward a definition of asthma for epidemiology. Am Rev Respir Dis 1992;146:633-637
21. 21. El-Zein M, Malo JL, Infante-Rivard C, et al. Incidence of probable occupational asthma and changes in airway caliber and responsiveness in apprentice welders. Eur Respir J 2003;22:513-518 (Pubitemid 37098935)
22. 22. Baur X. Immunologic cross-reactivity between different albumin-bound isocyanates. J Allergy Clin Immunol 1983;71:197-205. (Pubitemid 13138461)
23. 23. Aul DJ, Bhaumik A, Kennedy AL, et al. Specific IgG response to monomeric and polymeric MDI conjugates in subjects with respiratory reactions to isocyanates. J Allergy Clin Immunol 1999;103:749-755 (Pubitemid 29297573)
24. 24. Malo JL, Lemiere C, Desjardins A, et al. Prevalence and intensity of rhinoconjunctivitis in subjects with occupational asthma. Eur Respir J 1997;10:1513-1515 (Pubitemid 27311064)
25. 25. Karjalainen A, Martikainen R, Klaukka T, et al. Risk of asthma among Finnish patients with occupational rhinitis. Chest 2003;123:283-288 (Pubitemid 36126743)
26. 26. Portengen L, de Meer G, Doekes G, et al. Immunoglobulin G4 antibodies to rat urinary allergens, sensitization and symptomatic allergy in laboratory animal workers. Clin Exp Allergy 2004;34:1243-1250 (Pubitemid 39093064)
27. 27. Lee D, Edwards RG, Dewdney JM. Measurement of IgG subclasses in the sera of laboratory workers exposed to rats. Int Arch Allergy Appl Immunol 1988;87:222-224 (Pubitemid 18266004)
28. Shusterman D. Individual factors in nasal chemesthesis. Chem Senses 2002;27:551-564
29. 29. Nouri-Aria KT, Wachholz PA, Francis JN, et al. Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses ad blocking IgG activity. J Immunol 2004;172:3252-3259 (Pubitemid 38263717)
30. 30. Francis JN, Larche M. Peptide-based vaccination: where do we stand? Curr Opin Allergy Clin Immunol 2005;5:537-613 (Pubitemid 41679990)
31. 31. Akdis CA, Blase K. IL-10-induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: two key steps in specific immunotherapy. FASEB J 1999;13:603-609 (Pubitemid 29156392)