Localization of human T-cell leukemia virus type 1 Tax to subnuclear compartments that overlap with interchromatin speckles

Journal of Virology

Volumn 70, Issue 9, 1996, Pages 6347-6357

  Semmes, Oliver J ^a   Jeang, Kuan Teh ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CHROMATIN; HUMAN T CELL LEUKEMIA VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION;

EID: 0029840633     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.9.6347-6357.1996     Document Type: Article

References (63)

1. Abmayr, S. M., R. Reed, and T. Maniatis. 1988. Identification of a functional mammalian spliceosome containing unspliced pre-mRNA. Proc. Natl. Acad. Sci. USA 85:7216-7220.
2. Adya, N., and C. Z. Giam. 1995. Distinct regions in human T-cell lymphotropic virus type I Tax mediate interactions with activator protein CREB and basal transcription factors. J. Virol. 69:1834-1841.
3. Angel, P., K. Hattori, T. Smeal, and M. Karin. 1988. The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. Cell 55:875-885.
4. Beraud, C., G. Lombard-Platet, Y. Michal, and P. Jalinot. 1991. Binding of the HTLV-I Tax1 transactivator to the inducible 21 bp enhancer is mediated by the cellular factor HEB1. EMBO J. 10:3795-3803.
5. Beven, A. F., G. G. Simpson, J. W. Brown, and P. J. Shaw. 1995. The organization of spliceosomal components in the nuclei of higher plants. J. Cell Sci. 108:509-518.
6. Cann, A. J., J. D. Rosenblatt, W. Wachsman, N. P. Shah, and I. S. Chen. 1985. Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulation. Nature (London) 318:571-574.
7. Carmo-Fonseca, M., R. Pepperkok, M. T. Carvalho, and A. I. Lamond. 1992. Transcription-dependent colocaiization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies. J. Cell Biol. 117:1-14.
8. Carter, K. C., and J. B. Lawrence. 1991. DNA and RNA within the nucleus: how much sequence-specific spatial organization? J. Cell. Biochem. 47:124-129.
9. Delannoy, P., and M. H. Caruthers. 1991. Detection and characterization of a factor which rescues spliceosome assembly from a heat-inactivated HeLa cell nuclear extract. Mol. Cell. Biol. 11:3425-3431.
10. Dreyfuss, G., M. J. Matunis, S. Pinol-Roma, and C. G. Burd. 1993. hnRNP proteins and the biogenesis of mRNA. Annu. Rev. Biochem. 62:289-321.
11. Fakan, S., G. Leser, and T. E. Martin. 1984. Ultrastructural distribution of nuclear ribonucleoproteins as visualized by immunocytochemistry on thin sections. J. Cell Biol. 98:358-363.
12. Felber, B. K., H. Paskalis, C. Kleinman-Ewing, F. Wong-Staal, and G. N. Pavlakis. 1985. The pX protein of HTLV-1 is a transcriptional activator of its long terminal repeats. Science 229:675-679.
13. Feuer, G., and I. S. Chen. 1992. Mechanisms of human T-cell leukemia virus-induced leukemogenesis. Biochim. Biophys. Acta 1114:223-233.
14. Franklin, A. A., and J. K. Nyborg. 1995. Mechanisms of Tax regulation of human T cell leukemia virus type I gene expression. J. Biomed. Sci. 2:17-29.
15. Fu, X.-D., and T. Maniatls. 1990. Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature (London) 343:437-441.
16. Fujii, M., T. Niki, T. Mori, T. Matsuda, M. Matsui, N. Nomura, and M. Seiki. 1991. HTLV-1 Tax induces expression of various immediate early serum responsive genes. Oncogene 6:1023-1029.
17. Furukawa, Y., M. Osame, R. Kubota, M. Tara, and M. Yoshida. 1995. Human T-cell leukemia virus type-1 (HTLV-1) Tax is expressed at the same level in infected cells of HTLV-1-associated myelopathy or tropical spastic paraparesis patients as in asymptomatic carriers but at a lower level in adult T-cell leukemia cells. Blood 85:1865-1870.
18. Gall, J. G. 1991. Spliceosomes and snurposomes. Science 252:1499-1500.
19. Goren, I., O. J. Semmes, K.-T. Jeang, and K. Moelling. 1995. Amino terminus of Tax required for interaction with CREB. J. Virol. 69:5806-5811.
20. Graham, F. L., and A. J. van der Eb. 1973. Transformation of rat cells by DNA of human adenovirus 5. Virology 54:536-539.
21. Hozak, P., A. B. Hassan, D. A. Jackson, and P. R. Cook. 1993. Visualization of replication factories attached to nucleoskeleton. Cell 73:361-373.
22. Huang, S., and D. L. Spector. 1991. Nascent pre-mRNA transcripts are associated with nuclear regions enriched in splicing factors. Genes Dev. 5:2288-2302.
23. Jackson, D. A., A. B. Hassan, R. J. Errington, and P. R. Cook. 1993 Visualization of focal sites of transcription within human nuclei. EMBO J. 12: 1059-1065.
24. Jacobson, S., H. Shida, D. E. McFarlin, A. S. Fauci, and S. Koenig. 1990. Circulating CD8+ cytotoxic T lymphocytes specific for HTLV-I pX in patients with HTLV-I associated neurological disease. Nature (London) 348: 245-248.
25. Jeang, K. T., I. Boros, J. Brady, M. Radonovich, and G. Khoury. 1988. Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence. J. Virol. 62:4499-4509.
26. x protein in eucaryotic cells by using a baculovirus expression vector. J. Virol. 61:708-713.
27. Jeang, K. T., D. R. Rawlins, P. J. Rosenfeld, J. H. Shero, T. J. Kelly, and G. S. Hayward. 1987. Multiple tandemly repeated binding sites for cellular nuclear factor 1 that surround the major immediate-early promoters of simian and human cytomegalovirus. J. Virol. 61:1559-1570.
28. Jeang, K. T., S. G. Widen, O. J. Semmes, and S. H. Wilson. 1990. HTLV-I trans-activator protein, Tax, is a trans-repressor of the human beta-polymerase gene. Science 247:1082-1084.
29. Jimenez-Garcia, L. F., and D. L. Spector. 1993. In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism. Cell 73: 47-59.
30. Krainer, A. R., T. Maniatis, B. Ruskin, and M. R. Green. 1984. Normal and mutant human beta-globin pre-mRNAs are faithfully and efficiently spliced in vitro. Cell 36:993-1005.
31. Lawrence, J. B., K. C. Carter, and X. Xing. 1993. Probing functional organization within the nucleus: is genome structure integrated with RNA metabolism? Cold Spring Harbor Symp. Quant. Biol. 58:807-818.
32. Mahl, P., Y. Lutz, E. Puvion, and J. P. Fuchs. 1989. Rapid effect of heat shock on two heterogeneous nuclear ribonucleoprotein-associated antigens in HeLa cells. J. Cell Biol. 109:1921-1935.
33. Majune, F., O. J. Semmes, and K. T. Jeang. 1993. Induction of micronuclei by HTLV-I Tax: a cellular assay for function. Virology 193:456-459.
34. Matthews, M. A., R. B. Markowitz, and W. S. Dynan. 1992. In vitro activation of transcription by the human T-cell leukemia virus type I Tax protein. Mol. Cell. Biol. 12:1986-1996.
35. McKnight, S. L., and K. R. Yamamoto. 1992. Transcriptional regulation, p. 237-289. Cold Spring Harbor Laboratory Press, Plainview, N.Y.
36. Mitchell, P. J., and R. Tjian. 1989. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245:371-378.
37. tax protein in the human T-cell line, Jurkat. J. Virol. 63:3220-3226.
38. Nyborg, J. K., and W. S. Dynan. 1990. Interaction of cellular proteins with the human T-cell leukemia virus type 1 transcriptional control region. Purification of cellular proteins that bind the 21-base pair repeat elements. J. Biol. Chem. 265:8230-8236.
39. Nyborg, J. K., M. A. Matthews, J. Yucel, L. Walls, W. T. Golde, W. S. Dynan, and W. Wachsman. 1990. Interaction of host cell proteins with the human T-cell leukemia virus type I transcriptional control region. II. A comprehensive map of protein-binding sites facilitates construction of a simple chimeric promoter responsive to the viral tax2 gene product. J. Biol. Chem. 265:8237-8242.
40. Ptashne, M., and A. A. Gann. 1990. Activators and targets. Nature (London) 346:329-331.
41. Reed, R., J. Griffith, and T. Maniatis. 1988. Purification and visualization of native spliceosomes. Cell 53:949-961.
42. Seeler, J. S., C. Muchardt, M. Podar, and R. B. Gaynor. 1993. Regulatory elements involved in Tax-mediated transactivation of the HTLV-I LTR. Virology 196:442-450.
43. Seiki, M., J. Inoue, T. Takeda, and M. Yoshida. 1986. Direct evidence that p40x of human T-cell leukemia virus type I is a trans-acting transcriptional activator. EMBO J. 5:561-565.
44. Semmes, O. J., and K. T. Jeang. 1992. Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteins. J. Virol. 66:7183-7192.
45. Semmes, O. J., and K. T. Jeang. 1995. Definition of a minimal activation domain in human T-cell leukemia virus type I Tax. J. Virol. 69:1827-1833.
46. Shukla, R. R., Z. Dominski, T. Zwierzynski, and R. Kole. 1990. Inactivation of splicing factors in HeLa cells subjected to heat shock. J. Biol. Chem. 265:20377-20383.
47. Smith, M. R., and W. C. Greene. 1991. Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia. J. Clin. Invest. 87:761-766.
48. Sodroski, J. 1992. The human T-cell leukemia virus (HTLV) transactivator (Tax) protein. Biochim. Biophys. Acta 1114:19-29.
49. Spector, D. L. 1990. Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles. Proc. Natl. Acad. Sci. USA 87:147-151.
50. Spector, D. L. 1993. Macromolecular domains within the cell nucleus. Annu. Rev. Cell Biol. 9:265-315.
51. Spector, D. L., X. D. Fu, and T. Maniatis. 1991. Associations between distinct pre-mRNA splicing components and the cell nucleus. EMBO J. 10:3467-3481.
52. Spector, D. L., W. H. Schrier, and H. Busch. 1983. Immunoelectron microscopic localization of snRNPs. Biol. Cell 49:1-10.
53. Tan, E. M., E. K. Chan, K. F. Sullivan, and R. L. Rubin. 1988. Antinuclear antibodies (ANAs): diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity. Clin. Immunol. Immunopathol. 47:121-141.
54. Tan, T. H., M. Horikoshi, and R. G. Roeder. 1989. Purification and characterization of multiple nuclear factors that bind to the TAX-inducible enhancer within the human T-cell leukemia virus type 1 long terminal repeat. Mol. Cell. Biol. 9:1733-1745.
55. Tjian, R., and T. Maniatis. 1994. Transcriptional activation: a complex puzzle with few easy pieces. Cell 77:5-8.
56. Utans, U., S. E. Behrens, R. Luhrmann, R. Kole, and A. Kramer. 1992. A splicing factor that is inactivated during in vivo heat shock is functionally equivalent to the [U4/U6/U5] triple snRNP-specific proteins. Genes Dev. 6:631-641.
57. Wansink, D. G., W. Schul, I. van der Kraan, B. van Steensel, R. van Driel, and L. de Jong. 1993. Fluorescent labeling of nascent RNA reveals transcription by RNA polymerase II in domains scattered throughout the nucleus. J. Cell Biol. 122:283-293.
58. Wansink, D. G., R. van Driel, and L. de Jong. 1994. Organization of premRNA metabolism in the cell nucleus. Mol. Biol. Rep. 20:45-55.
59. Welch, W. J. 1987. The mammalian heat shock (or stress) response: a cellular defense mechanism. Adv. Exp. Med. Biol. 225:287-304.
60. Wright-Sandor, L. G., M. Reichlin, and S. L. Tobin. 1989. Alteration by heat shock and immunological characterization of Drosophila small nuclear ribonucleoproteins. J. Cell Biol. 108:2007-2016.
61. Xu, V. L., N. Adya, E. Siores, Q. S. Gao, and C. Z. Giam. 1990. Cellular factors involved in transcription and Tax-mediated trans-activation directed by the TGACGT motifs in human T-cell leukemia virus type I promoter. J. Biol. Chem. 265:20285-20292.
62. Yin, M. J., E. J. Paulssen, J. S. Seeler, and R. B. Gaynor. 1995. Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I tax and CREB. J. Virol. 69:3420-3432.
63. Zhao, L. J., and C. Z. Giam. 1991. Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer. Proc. Natl. Acad. Sci. USA 88:11445-11449.