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Volumn 80, Issue 6, 2009, Pages 1099-1106

A dominant loss-of-function GJA1 (Cx43) mutant impairs parturition in the mouse

Author keywords

Connexin43; Gap junction; Intercellular communication; Myometrium; Oculodentodigital dysplasia; ODDD; Oxytocin; Pregnancy; Uterus

Indexed keywords

CONNEXIN 43; ESTROGEN; OXYTOCIN;

EID: 66149085991     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.108.071969     Document Type: Article
Times cited : (47)

References (35)
  • 1
    • 33645002735 scopus 로고    scopus 로고
    • Life cycle of connexins in health and disease
    • Laird DW. Life cycle of connexins in health and disease. Biochem J 2006; 394:527-543.
    • (2006) Biochem J , vol.394 , pp. 527-543
    • Laird, D.W.1
  • 2
    • 66149105984 scopus 로고    scopus 로고
    • Roles of connexins in female reproduction
    • Harris A, Locke D (eds.), Totowa, NJ: Humana Press
    • Kidder GM, Winterhager E. Roles of connexins in female reproduction. In: Harris A, Locke D (eds.), Connexins: A Guide. Totowa, NJ: Humana Press; 2008.
    • (2008) Connexins: a Guide
    • Kidder, G.M.1    Winterhager, E.2
  • 3
    • 0029877670 scopus 로고    scopus 로고
    • Connexin-26 and connexin-43 are differentially expressed and regulated in the rat myometrium throughout late pregnancy and with the onset of labor
    • DOI 10.1210/en.137.5.1545
    • Orsino A, Taylor CV, Lye SJ. Connexin-26 and connexin-43 are differentially expressed and regulated in the rat myometrium throughout late pregnancy and with the onset of labor. Endocrinology 1996; 137:1545-1553. (Pubitemid 26139688)
    • (1996) Endocrinology , vol.137 , Issue.5 , pp. 1545-1553
    • Orsino, A.1    Taylor, C.V.2    Lye, S.J.3
  • 4
    • 0029859224 scopus 로고    scopus 로고
    • Rat uterine myometrium contains the gap junction protein connexin45, which has a differing temporal expression pattern from connexin43
    • DOI 10.1016/S0002-9378(96)80012-3
    • Albrecht JL, Atal NS, Tadros PN, Orsino A, Lye SJ, Sadovsky Y, Beyer EC. Rat uterine myometrium contains the gap junction protein connexin45, which has a differing temporal expression pattern from connexin43. Am J Obstet Gynecol 1996; 175:853-858. (Pubitemid 26357942)
    • (1996) American Journal of Obstetrics and Gynecology , vol.175 , Issue.4 , pp. 853-858
    • Albrecht, J.L.1    Atal, N.S.2    Tadros, P.N.3    Orsino, A.4    Lye, S.J.5    Sadovsky, Y.6    Beyer, E.C.7
  • 6
    • 0030722611 scopus 로고    scopus 로고
    • Expression of connexin-43 and connexin-26 in the rat myometrium during pregnancy and labor is differentially regulated by mechanical and hormonal signals
    • Ou CW, Orsino A, Lye SJ. Expression of connexin-43 and connexin-26 in the rat myometrium during pregnancy and labor is differentially regulated by mechanical and hormonal signals. Endocrinology 1997; 138:5398-5407. (Pubitemid 27509702)
    • (1997) Endocrinology , vol.138 , Issue.12 , pp. 5398-5407
    • Ou, C.-W.1    Orsino, A.2    Lye, S.J.3
  • 7
    • 0019955856 scopus 로고
    • Improved electrical coupling in uterine smooth muscle is associated with increased numbers of gap junctions at parturition
    • DOI 10.1085/jgp.80.3.353
    • Sims SM, Daniel EE, Garfield RE. Improved electrical coupling in uterine smooth muscle is associated with increased numbers of gap junctions at parturition. J Gen Physiol 1982; 80:353-375. (Pubitemid 12035379)
    • (1982) Journal of General Physiology , vol.80 , Issue.3 , pp. 353-375
    • Sims, S.M.1    Daniel, E.E.2    Garfield, R.E.3
  • 8
    • 0026714726 scopus 로고
    • Modulation of cell-to-cell coupling between myometrial cells of the human uterus during pregnancy
    • Sakai N, Tabb T, Garfield RE. Modulation of cell-to-cell coupling between myometrial cells of the human uterus during pregnancy. Am J Obstet Gynecol 1992; 167:472-480.
    • (1992) Am J Obstet Gynecol , vol.167 , pp. 472-480
    • Sakai, N.1    Tabb, T.2    Garfield, R.E.3
  • 9
    • 0029763314 scopus 로고    scopus 로고
    • Voltage-clamp studies of gap junctions between uterine muscle cells during term and preterm labor
    • Miyoshi H, Boyle MB, MacKay LB, Garfield RE. Voltage-clamp studies of gap junctions between uterine muscle cells during term and preterm labor. Biophys J 1996; 71:1324-1334. (Pubitemid 26299771)
    • (1996) Biophysical Journal , vol.71 , Issue.3 , pp. 1324-1334
    • Miyoshi, H.1    Boyle, M.B.2    MacKay, L.B.3    Garfield, R.E.4
  • 11
    • 0027174170 scopus 로고
    • Increased expression of connexin-43 in the rat myometrium during labor is associated with an increase in the plasma estrogen: Progesterone ratio
    • DOI 10.1210/en.132.6.2380
    • Lye SJ, Nicholson BJ, Mascarenhas M, MacKenzie L, Petrocelli T. Increased expression of connexin-43 in the rat myometrium during labor is associated with an increase in the plasma estrogen:progesterone ratio. Endocrinology 1993; 132:2380-2386. (Pubitemid 23156885)
    • (1993) Endocrinology , vol.132 , Issue.6 , pp. 2380-2386
    • Lye, S.J.1    Nicholson, B.J.2    Mascarenhas, M.3    MacKenzie, L.4    Petrocelli, T.5
  • 12
    • 0034932498 scopus 로고    scopus 로고
    • Oestriol and oestradiol increase cell to cell communication and connexin43 protein expression in human myometrium
    • Di WL, Lachelin GC, McGarrigle HH, Thomas NS, Becker DL. Oestriol and oestradiol increase cell to cell communication and connexin43 protein expression in human myometrium. Mol Hum Reprod 2001; 7:671-679. (Pubitemid 32633417)
    • (2001) Molecular Human Reproduction , vol.7 , Issue.7 , pp. 671-679
    • Di, W.-L.1    Lachelin, G.C.L.2    McGarrigle, H.H.G.3    Thomas, N.S.B.4    Becker, D.L.5
  • 14
    • 0036255381 scopus 로고    scopus 로고
    • Neurological manifestations of the oculodentodigital dysplasia syndrome
    • DOI 10.1007/s004150200068
    • Loddenkemper T, Grote K, Evers S, Oelerich M, Stogbauer F. Neurological manifestations of the oculodentodigital dysplasia syndrome. J Neurol 2002; 249:584-595. (Pubitemid 34507833)
    • (2002) Journal of Neurology , vol.249 , Issue.5 , pp. 584-595
    • Loddenkemper, T.1    Grote, K.2    Evers, S.3    Oelerich, M.4    Stogbauer, F.5
  • 18
    • 23744507557 scopus 로고    scopus 로고
    • Functional characterization of connexin43 mutations found in patients with oculodentodigital dysplasia
    • Shibayama J, Paznekas W, Seki A, Taffet S, Jabs EW, Delmar M, Musa H. Functional characterization of connexin43 mutations found in patients with oculodentodigital dysplasia. Circ Res 2005; 96:e83-e91.
    • (2005) Circ Res , vol.96
    • Shibayama, J.1    Paznekas, W.2    Seki, A.3    Taffet, S.4    Jabs, E.W.5    Delmar, M.6    Musa, H.7
  • 21
    • 44449137493 scopus 로고    scopus 로고
    • ODDD-linked Cx43 mutants reduce endogenous Cx43 expression and function in osteoblasts and inhibit late stage differentiation
    • McLachlan E, Plante I, Shao Q, Tong D, Kidder GM, Bernier SM, Laird DW. ODDD-linked Cx43 mutants reduce endogenous Cx43 expression and function in osteoblasts and inhibit late stage differentiation. J Bone Miner Res 2008; 23:928-938.
    • (2008) J Bone Miner Res , vol.23 , pp. 928-938
    • McLachlan, E.1    Plante, I.2    Shao, Q.3    Tong, D.4    Kidder, G.M.5    Bernier, S.M.6    Laird, D.W.7
  • 23
    • 0034778932 scopus 로고    scopus 로고
    • Pharmacological techniques for the in vitro study of the uterus
    • DOI 10.1016/S1056-8719(01)00143-5, PII S1056871901001435
    • Crankshaw DJ. Pharmacological techniques for the in vitro study of the uterus. J Pharmacol Toxicol Methods 2001; 45:123-140. (Pubitemid 33001469)
    • (2001) Journal of Pharmacological and Toxicological Methods , vol.45 , Issue.2 , pp. 123-140
    • Crankshaw, D.J.1
  • 24
    • 33645237754 scopus 로고    scopus 로고
    • Effect of the oestrous cycle, pregnancy and uterine region on the responsiveness of the isolated mouse uterus to prostaglandin F(2alpha) and the thromboxane mimetic U46619
    • Griffiths AL, Marshall KM, Senior J, Fleming C, Woodward DF. Effect of the oestrous cycle, pregnancy and uterine region on the responsiveness of the isolated mouse uterus to prostaglandin F(2alpha) and the thromboxane mimetic U46619. J Endocrinol 2006; 188:569-577.
    • (2006) J Endocrinol , vol.188 , pp. 569-577
    • Griffiths, A.L.1    Marshall, K.M.2    Senior, J.3    Fleming, C.4    Woodward, D.F.5
  • 26
    • 0022881517 scopus 로고
    • A monoclonal antibody against α-smooth muscle actin: A new probe for smooth muscle differentiation
    • DOI 10.1083/jcb.103.6.2787
    • Skalli O, Ropraz P, Trzeciak A, Benzonana G, Gillessen D, Gabbiani G. A monoclonal antibody against a-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol 1986; 103:2787-2796. (Pubitemid 17008024)
    • (1986) Journal of Cell Biology , vol.103 , Issue.6 , pp. 2787-2796
    • Skalli, O.1    Ropraz, P.2    Trzeciak, A.3
  • 27
    • 33644816465 scopus 로고    scopus 로고
    • Patch-clamp study reveals that the importance of connexin43-mediated gap junctional communication for ovarian folliculogenesis is strain specific in the mouse
    • Tong D, Gittens JE, Kidder GM, Bai D. Patch-clamp study reveals that the importance of connexin43-mediated gap junctional communication for ovarian folliculogenesis is strain specific in the mouse. Am J Physiol Cell Physiol 2006; 290:C290-C297.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Tong, D.1    Gittens, J.E.2    Kidder, G.M.3    Bai, D.4
  • 29
    • 44349184836 scopus 로고    scopus 로고
    • Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia
    • Plante I, Laird DW. Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia. Dev Biol 2008; 318:312-322.
    • (2008) Dev Biol , vol.318 , pp. 312-322
    • Plante, I.1    Laird, D.W.2
  • 34
    • 33846456301 scopus 로고    scopus 로고
    • Parturition
    • Smith R. Parturition. N Engl J Med 2007; 356:271-283.
    • (2007) N Engl J Med , vol.356 , pp. 271-283
    • Smith, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.