Nitroglycerin sensitises in healthy subjects CNS structures involved in migraine pathophysiology: Evidence from a study of nociceptive blink reflexes and visual evoked potentials

Pain

Volumn 144, Issue 1-2, 2009, Pages 156-161

  Di Clemente, Laura ^a,b   Coppola, Gianluca ^c   Magis, Delphine ^a   Gérardy, Pierre Yves ^a   Fumal, Arnaud ^a   De Pasqua, Victor ^a   Di Piero, Vittorio ^b   Schoenen, Jean ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c IRCCS FONDAZIONE BIETTI   (Italy)

Author keywords

Evoked potentials; Migraine; Nitroglycerin; Nociceptive blink reflex

Indexed keywords

GLYCERYL TRINITRATE; PLACEBO;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CENTRAL NERVOUS SYSTEM; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG SENSITIZATION; EVOKED VISUAL RESPONSE; EYELID REFLEX; FEMALE; HABITUATION; HUMAN; MALE; MIGRAINE; NOCICEPTIVE STIMULATION; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ADULT; ANALYSIS OF VARIANCE; BLINKING; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; ELECTRIC STIMULATION; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS, VISUAL; FEMALE; HABITUATION, PSYCHOPHYSIOLOGIC; HUMANS; MALE; MIGRAINE DISORDERS; NITRIC OXIDE DONORS; NITROGLYCERIN; PAIN; PAIN THRESHOLD; YOUNG ADULT;

EID: 66049129260     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2009.04.018     Document Type: Article

References (39)

1. Afra J., Proietti Cecchini A., Sandor P.S., and Schoenen J. Comparison of visual and auditory evoked cortical potentials in migraine patients between attacks. Clin Neurophysiol 111 (2000) 1124-1129
2. Afra J., Sandor P.S., and Schoenen J. Habituation of visual and intensity dependence of auditory evoked cortical potentials tends to normalize just before and during the migraine attack. Cephalalgia 20 (2000) 714-719
3. Afridi S.K., Giffin N.J., Kaube H., Friston K.J., Ward N.S., Frackowiak R.S., and Goadsby P.J. A positron emission tomographic study in spontaneous migraine. Arch Neurol 62 (2005) 1270-1275
4. Ahern G.P., Klyachko V.A., and Jackson M.B. CGMP and S-nitrosylation: two routes for modulation of neuronal excitability by NO. Trends Neurosci 25 (2002) 510-517
5. Buzzi M.G., Tassorelli C., and Nappi G. Peripheral and central activation of trigeminal pain pathways in migraine: data from experimental animal models. Cephalalgia 23 (2003) 1-4
6. Coppola G., Pierelli F., and Schoenen J. Is the cerebral cortex hyperexcitable or hyperresponsive in migraine?. Cephalalgia 27 (2007) 1427-1439
7. Costa A., Ravaglia S., Sances G., Antonaci F., Pucci E., and Nappi G. Nitric oxide pathway and response to nitroglycerin in cluster headache patients: plasma nitrite and citrulline levels. Cephalalgia 23 (2003) 407-413
8. De Tommaso M., Lo Sito L., Di Fruscolo O., Sardaro M., Prudenzano P.M., Lamberti P., and Livrea P. Lack of habituation of nociceptive evoked responses and pain sensitivity during migraine attack. Clin Neurophysiol 116 (2005) 1254-1264
9. Di Clemente L., Coppola G., Magis D., Fumal A., De Pasqua V., and Schoenen J. Nociceptive blink reflex and visual evoked potential habituations are correlated in migraine. Headache 45 (2005) 1388-1393
10. Di Clemente L., Coppola G., Magis D., Fumal A., De Pasqua V., Di Piero V., and Schoenen J. Interictal habituation deficit of the nociceptive blink reflex: an endophenotypic marker for presymptomatic migraine?. Brain 130 (2007) 765-770
11. Ellrich J., and Treede R.D. Characterization of blink reflex interneurons by activation of diffuse noxious inhibitory controls in man. Brain Res 803 (1998) 161-168
12. Hsieh J., Hannerz J., and Ingvar M. Right-lateralised central processing for pain of nitroglycerin-induced cluster headache. Pain 67 (1996) 59-68
13. Jones M.G., Lever I., Bingham S., Read S., McMahon S.B., and Parsons A. Nitric oxide potentiates response of trigeminal neurones to dural or facial stimulation in the rat. Cephalalgia 21 (2001) 643-655
14. Kara P., and Friedlander M.J. Arginine analogs modify signal detection by neurons in the visual cortex. J Neurosci 19 (1999) 5528-5548
15. Katsarava Z., Giffin N., Diener H.C., and Kaube H. Abnormal habituation of "nociceptive" blink reflex in migraine - evidence for increased excitability of trigeminal nociception. Cephalalgia 23 (2003) 814-819
16. Kaube H., Katsarava Z., Kaufer T., Diener H.C., and Ellrich J. A new method to increase nociception specificity of the human blink reflex. Clin Neurophysiol 111 (2000) 413-416
17. Kaube H., Katsarava Z., Prywara S., Drepper J., Ellrich J., and Diener H.C. Acute migraine headache. Possible sensitization of neurons in the spinal trigeminal nucleus?. Neurology 58 (2002) 1234-1238
18. Kowacs F., Giffin N.J., Putzki N., Goadsby P.J., and Kaube H. Nociceptive-specific blink reflex and glyceryl trinitrate infusion in healthy volunteers. Eur J Neurol 10 (2003) 295-299
19. Lambert G.A., Donaldson C., Boers P.M., and Zagami A.S. Activation of trigeminovascular neurons by glyceryl trinitrate. Brain Res 887 (2000) 203-210
20. May A., Bahra A., Buchel C., Frackowiak R.S., and Goadsby P.J. Hypothalamic activation in cluster headache attacks. Lancet 352 (1998) 275-278
21. May A., Bahra A., Buchel C., Frackowiak R.S., and Goadsby P.J. PET and MRA findings in cluster headache and MRA in experimental pain. Neurology 55 (2000) 1328-1335
22. Offenhauser N., Zinck T., Hoffmann J., Schiemann K., Schuh-Hofer S., Rohde W., Arnold G., Dirnagl U., Jansen-Olesen I., and Reuter U. CGRP release and c-fos expression within trigeminal nucleus caudalis of the rat following glyceryltrinitrate infusion. Cephalalgia 25 (2005) 225-236
23. Olesen J., Iversen H.K., and Thomsen L.L. Nitric oxide supersensitivity: a possible molecular mechanism of migraine pain. Neuroreport 4 (1993) 1027-1030
24. Pardutz A., Multon S., Malgrange B., Parducz A., Vecsei L., and Schoenen J. Systemic nitroglycerin increases nNOS levels in rat trigeminal nucleus caudalis. Neuroreport 11 (2000) 3071-3075
25. Read S.J., Smith M.I., Hunter A.J., and Parsons A.A. Enhanced nitric oxide release during cortical spreading depression following infusion of glyceryl trinitrate in the anaesthetized cat. Cephalalgia 17 (1997) 159-165
26. Reuter U., Bolay H., Jansen-Olensen I., Chiarugi A., Sanchez del Rio M., Letourneau R., Theoharides T.C., Waeber C., and Moskowitz M.A. Delayed inflammation in rat meninges: implications for migraine pathophysiology. Brain 124 (2001) 2490-2590
27. Sakai Y., Dobson C., Diksic M., Aubé M., and Hamel E. Sumatriptan normalizes the migraine attack-related increase in brain serotonin synthesis. Neurology 70 (2008) 431-439
28. Sances G., Tassorelli C., Pucci E., Ghiotto N., Sandrini G., and Nappi G. Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headaches. Cephalalgia 24 (2004) 110-119
29. Sandrini G., Tassorelli C., Cecchini A.P., Alfonsi E., and Nappi G. Effects of nimesulide on nitric oxide-induced hyperalgesia in humans - a neurophysiological study. Eur J Pharmacol 450 (2002) 259-262
30. Schoenen J. Deficient habituation of evoked cortical potentials in migraine: a link between brain biology, behavior and trigeminovascular activation?. Biomed Pharmacother 50 (1996) 71-78
31. Schoenen J., Ambrosini A., Sandor P.S., and Maertens de Noordhout A. Evoked potentials and transcranial magnetic stimulation in migraine: published data and viewpoint on their pathophysiologic significance. Clin Neurophysiol 114 (2003) 955-972
32. Schoenen J., Di Clemente L., Vandenheede M., Fumal A., De Pasqua V., Mouchamps M., Remacle J.M., and de Noordhout A.M. Hypothalamic stimulation in chronic cluster headache: a pilot study of efficacy and mode of action. Brain 128 (2005) 940-947
33. Sicuteri F., Del Bene E., Poggioni M., and Bonazzi A. Unmasking latent dysnociception in healthy subjects. Headache 27 (1987) 180-185
34. Siniatchkin M., Gerber W.D., Kropp P., and Vein A. How the brain anticipates an attack: a study of neurophysiological periodicity in migraine. Funct Neurol 14 (1999) 69-77
35. Tassorelli C., Joseph S.A., Buzzi M.G., and Nappi G. The effects on the central nervous system of nitroglycerin - putative mechanisms and mediators. Prog Neurobiol 57 (1999) 607-624
36. Tassorelli C., Joseph S.A., and Nappi G. Central effects of nitroglycerin in the rat: new perspectives in migraine research. Funct Neurol 11 (1996) 219-235
37. Thomsen L., Kruuse C., Iversen H., and Olesen J. A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks. Eur J Neurol 1 (1994) 73-80
38. Weiller C., May A., Limmroth V., Juptner M., Kaube H., Schayck R.V., Coenen H.H., and Diener H.C. Brain stem activation in spontaneous human migraine attacks. Nat Med 1 (1995) 658-660
39. Yargiçoǧlu P., Yaraş N., Aǧar A., Gümüslü S., Abidin I., and Bilmen S. Effects of N-nitro l-arginine methyl ester (L-NAME), a potent nitric oxide synthase inhibitor, on visual evoked potentials of rats exposed to different experimental stress models. Acta Physiol Scand 180 (2004) 307-316