메뉴 건너뛰기




Volumn 46, Issue 1, 2009, Pages 135-144

Sustained antinociceptive effect of cannabinoid receptor agonist WIN 55,212-2 over time in rat model of neuropathic spinal cord injury pain

Author keywords

Allodynia; Alternative medicine; Chronic pain; Natural product; Neuropathic pain; Opiate; Rat model; Rehabilitation; Spinal cord injury; Tolerance

Indexed keywords

ALLODYNIA; ALTERNATIVE MEDICINE; CHRONIC PAIN; NATURAL PRODUCT; NEUROPATHIC PAIN; OPIATE; RAT MODEL; REHABILITATION; SPINAL CORD INJURY; TOLERANCE;

EID: 65949107529     PISSN: 07487711     EISSN: 07487711     Source Type: Journal    
DOI: 10.1682/JRRD.2008.04.0049     Document Type: Article
Times cited : (28)

References (53)
  • 1
    • 65949090472 scopus 로고    scopus 로고
    • Spinal cord injury rehabilitation
    • Dillingham TR, Belandres PV, editors. Washington (DC): The Borden Institute
    • Little JW, Goldstein B, Hammond MC. Spinal cord injury rehabilitation. In: Dillingham TR, Belandres PV, editors. Vol.1, Textbook of military medicine. Washington (DC): The Borden Institute; 1998. p. 161-205.
    • (1998) Vol.1, Textbook of Military Medicine , pp. 161-205
    • Little, J.W.1    Goldstein, B.2    Hammond, M.C.3
  • 4
    • 33645695567 scopus 로고    scopus 로고
    • Prevalence and characteristics of chronic pain in veterans with spinal cord injury
    • Rintala DH, Holmes SA, Fiess RN, Courtade D, Loubser PG. Prevalence and characteristics of chronic pain in veterans with spinal cord injury. J Rehabil Res Dev. 2005;42(5):573-584
    • (2005) J Rehabil Res Dev , vol.42 , Issue.5 , pp. 573-584
    • Rintala, D.H.1    Holmes, S.A.2    Fiess, R.N.3    Courtade, D.4    Loubser, P.G.5
  • 6
    • 77049163461 scopus 로고
    • Pain in paraplegia: Clinical management and surgical treatment
    • Botterell EH, Callaghan JC, Jousse AT. Pain in paraplegia: Clinical management and surgical treatment. Proc R Soc Med. 1954;47(4):281-288
    • (1954) Proc R Soc Med , vol.47 , Issue.4 , pp. 281-288
    • Botterell, E.H.1    Callaghan, J.C.2    Jousse, A.T.3
  • 8
    • 0001681878 scopus 로고
    • The new viewpoint toward spinal cord injuries
    • Kennedy RH. The new viewpoint toward spinal cord injuries. Ann Surg. 1946;124(6):1057-62. [PMID: 17858895] DOI:10.1097/00000658-194612000-194700007
    • (1946) Ann Surg , vol.124 , Issue.6 , pp. 1057-1062
    • Kennedy, R.H.1
  • 9
    • 0027181508 scopus 로고
    • Long-term survival of veterans with traumatic spinal cord injury
    • Samsa GP, Patrick CH, Feussner JR. Long-term survival of veterans with traumatic spinal cord injury. Arch Neurol. 1993;50:909-914
    • (1993) Arch Neurol , vol.50 , pp. 909-914
    • Samsa, G.P.1    Patrick, C.H.2    Feussner, J.R.3
  • 10
    • 0035090029 scopus 로고    scopus 로고
    • Pain following spinal cord injury
    • Siddall PJ, Loeser JD. Pain following spinal cord injury. Spinal Cord. 2001;39(2):63-73.
    • (2001) Spinal Cord , vol.39 , Issue.2 , pp. 63-73
    • Siddall, P.J.1    Loeser, J.D.2
  • 11
    • 0035893505 scopus 로고    scopus 로고
    • Pain and spasticity after spinal cord injury: Mechanisms and treatment
    • Burchiel KJ, Hsu FP. Pain and spasticity after spinal cord injury: Mechanisms and treatment. Spine. 2001;26(Suppl 24):S146-60. [PMID: 11805622] DOI:10.1097/00007632-200112151-200200024
    • (2001) Spine , vol.26 , Issue.SUPPL. 24
    • Burchiel, K.J.1    Hsu, F.P.2
  • 12
    • 1242314826 scopus 로고    scopus 로고
    • Spinal cord injury pain-Mechanisms and treatment
    • Finnerup NB, Jensen TS. Spinal cord injury pain-Mechanisms and treatment. Eur J Neurol. 2004;11(2):73-82.
    • (2004) Eur J Neurol , vol.11 , Issue.2 , pp. 73-82
    • Finnerup, N.B.1    Jensen, T.S.2
  • 14
    • 0036462447 scopus 로고    scopus 로고
    • Cannabinoids: A real prospect for pain relief?
    • Iversen L, Chapman V. Cannabinoids: A real prospect for pain relief? Curr Opin Pharmacol. 2002;2(1):50-55.
    • (2002) Curr Opin Pharmacol , vol.2 , Issue.1 , pp. 50-55
    • Iversen, L.1    Chapman, V.2
  • 15
    • 33847326874 scopus 로고    scopus 로고
    • Antinociceptive effect of cannabinoid agonist WIN 55,212-2 in rats with a spinal cord injury
    • Hama A, Sagen J. Antinociceptive effect of cannabinoid agonist WIN 55,212-2 in rats with a spinal cord injury. Exp Neurol. 2007;204(1):454-457
    • (2007) Exp Neurol , vol.204 , Issue.1 , pp. 454-457
    • Hama, A.1    Sagen, J.2
  • 16
    • 1542284124 scopus 로고    scopus 로고
    • Are oral cannabinoids safe and effective in refractory neuropathic pain?
    • DOI 10.1016/S1090-3801(03)00084-3
    • Attal N, Brasseur L, Guirimand D, Clermond-Gnamien S, Atlami S, Bouhassira D. Are oral cannabinoids safe and effective in refractory neuropathic pain? Eur J Pain. 2004;8(2):173-77. [PMID: 14987627] DOI:10.1016/S1090-3801(03) 00084-93 (Pubitemid 38325885)
    • (2004) European Journal of Pain , vol.8 , Issue.2 , pp. 173-177
    • Attal, N.1    Brasseur, L.2    Guirimand, D.3    Clermond-Gnamien, S.4    Atlami, S.5    Bouhassira, D.6
  • 17
    • 25444530723 scopus 로고    scopus 로고
    • Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis
    • DOI 10.1212/01.wnl.0000176753.45410.8b
    • Rog DJ, Nurmikko TJ, Friede T, Young CA. Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology. 2005;65(6):812-819 [PMID: 16186518] DOI:10.1212/01.wnl.0000176753.45410.8b (Pubitemid 41362120)
    • (2005) Neurology , vol.65 , Issue.6 , pp. 812-819
    • Rog, D.J.1    Nurmikko, T.J.2    Friede, T.3    Young, C.A.4
  • 18
    • 0035822343 scopus 로고    scopus 로고
    • Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review
    • Campbell FA, Tramer MR, Carroll D, Reynolds DJ, Moore RA, McQuay HJ. Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review. BMJ. 2001;323(7303):13-16.
    • (2001) BMJ , vol.323 , Issue.7303 , pp. 13-16
    • Campbell, F.A.1    Tramer, M.R.2    Carroll, D.3    Reynolds, D.J.4    Moore, R.A.5    McQuay, H.J.6
  • 19
    • 0028652717 scopus 로고
    • Analgesic action of acute and chronic intraspinally administered opiate and α-2-adrenergic agonists in chronic neuropathic pain
    • Levy R, Leiphart J, Dills C. Analgesic action of acute and chronic intraspinally administered opiate and α-2-adrenergic agonists in chronic neuropathic pain. Stereotact Funct Neurosurg. 1994;62(1-4):279-289
    • (1994) Stereotact Funct Neurosurg , vol.62 , Issue.1-4 , pp. 279-289
    • Levy, R.1    Leiphart, J.2    Dills, C.3
  • 20
    • 1242272173 scopus 로고    scopus 로고
    • Behavioral effects of cannabinoids show differential sensitivity to cannabinoid receptor blockade and tolerance development
    • De Vry J, Jentzsch KR, Kuhl E, Eckel G. Behavioral effects of cannabinoids show differential sensitivity to cannabinoid receptor blockade and tolerance development. Behav Pharmacol. 2004;15(1):1-12.
    • (2004) Behav Pharmacol , vol.15 , Issue.1 , pp. 1-12
    • De Vry, J.1    Jentzsch, K.R.2    Kuhl, E.3    Eckel, G.4
  • 22
    • 36448959087 scopus 로고    scopus 로고
    • Behavioral characterization and effect of clinical drugs in a rat model of pain following spinal cord compression
    • Hama A, Sagen J. Behavioral characterization and effect of clinical drugs in a rat model of pain following spinal cord compression. Brain Res. 2007;1185:117-128
    • (2007) Brain Res , vol.1185 , pp. 117-128
    • Hama, A.1    Sagen, J.2
  • 24
    • 0032890162 scopus 로고    scopus 로고
    • The induction of pain: An integrative review
    • Millan MJ. The induction of pain: An integrative review. Prog Neurobiol. 1999;57(1):1-164.
    • (1999) Prog Neurobiol , vol.57 , Issue.1 , pp. 1-164
    • Millan, M.J.1
  • 25
    • 0001978419 scopus 로고
    • The pharmacohistory of cannabis sativa
    • Mechoulam R, editor. Boca Raton (LA): CRC Press
    • Mechoulam R. The pharmacohistory of cannabis sativa. In: Mechoulam R, editor. Cannabinoids as therapeutic agents. Boca Raton (LA): CRC Press; 1986. p. 1-19.
    • (1986) Cannabinoids As Therapeutic Agents , pp. 1-19
    • Mechoulam, R.1
  • 26
    • 23044500716 scopus 로고    scopus 로고
    • Cannabinoids in anaesthesia and pain therapy
    • Azad SC, Rammes G. Cannabinoids in anaesthesia and pain therapy. Curr Opin Anaesthesiol. 2005;18(4):424-427
    • (2005) Curr Opin Anaesthesiol , vol.18 , Issue.4 , pp. 424-427
    • Azad, S.C.1    Rammes, G.2
  • 27
    • 0030944030 scopus 로고    scopus 로고
    • The selective cannabinoid antagonist SR 141716A blocks cannabinoid-induced antinociception in rats
    • Lichtman AH, Martin BR. The selective cannabinoid antagonist SR 141716A blocks cannabinoid-induced antinociception in rats. Pharmacol Biochem Behav. 1997;57(1-2):7-12.
    • (1997) Pharmacol Biochem Behav , vol.57 , Issue.1-2 , pp. 7-12
    • Lichtman, A.H.1    Martin, B.R.2
  • 29
    • 0034766553 scopus 로고    scopus 로고
    • Pharmacological actions and therapeutic uses of cannabis and cannabinoids
    • Kumar RN, Chambers WA, Pertwee RG. Pharmacological actions and therapeutic uses of cannabis and cannabinoids. Anaesthesia. 2001;56(11):1059- 1068
    • (2001) Anaesthesia , vol.56 , Issue.11 , pp. 1059-1068
    • Kumar, R.N.1    Chambers, W.A.2    Pertwee, R.G.3
  • 30
    • 34548483175 scopus 로고    scopus 로고
    • Cannabis, pain, and sleep: Lessons from therapeutic clinical trials of Sativex, a cannabisbased medicine
    • Russo EB, Guy GW, Robson PJ. Cannabis, pain, and sleep: Lessons from therapeutic clinical trials of Sativex, a cannabisbased medicine. Chem Biodivers. 2007;4(8):1729-1743
    • (2007) Chem Biodivers , vol.4 , Issue.8 , pp. 1729-1743
    • Russo, E.B.1    Guy, G.W.2    Robson, P.J.3
  • 35
    • 0030425575 scopus 로고    scopus 로고
    • Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
    • Showalter VM, Compton DR, Martin BR, Abood ME. Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands. J Pharmacol Exp Ther. 1996;278(3):989-999
    • (1996) J Pharmacol Exp Ther , vol.278 , Issue.3 , pp. 989-999
    • Showalter, V.M.1    Compton, D.R.2    Martin, B.R.3    Abood, M.E.4
  • 37
    • 0035059241 scopus 로고    scopus 로고
    • The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain
    • Fox A, Kesingland A, Gentry C, McNair K, Patel S, Urban L, James I. The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain. Pain. 2001;92(1-2):91-100.
    • (2001) Pain , vol.92 , Issue.1-2 , pp. 91-100
    • Fox, A.1    Kesingland, A.2    Gentry, C.3    McNair, K.4    Patel, S.5    Urban, L.6    James, I.7
  • 38
    • 0032056333 scopus 로고    scopus 로고
    • Characterization of Δ9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats
    • Smith FL, Fujimori K, Lowe J, Welch SP. Characterization of Δ9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. Pharmacol Biochem Behav. 1998;60(1):183-91.
    • (1998) Pharmacol Biochem Behav , vol.60 , Issue.1 , pp. 183-91
    • Smith, F.L.1    Fujimori, K.2    Lowe, J.3    Welch, S.P.4
  • 40
    • 1242296234 scopus 로고    scopus 로고
    • Repeated treatment with the synthetic cannabinoid WIN 55,212-2 reduces both hyperalgesia and production of pronociceptive mediators in a rat model of neuropathic pain
    • Costa B, Colleoni M, Conti S, Trovato AE, Bianchi M, Sotgiu ML, Giagnoni G. Repeated treatment with the synthetic cannabinoid WIN 55,212-2 reduces both hyperalgesia and production of pronociceptive mediators in a rat model of neuropathic pain. Br J Pharmacol. 2004;141(1):4-8. [PMID: 14662732] DOI:10.1038/sj.bjp.0705587
    • (2004) Br J Pharmacol , vol.141 , Issue.1 , pp. 4-8
    • Costa, B.1    Colleoni, M.2    Conti, S.3    Trovato, A.E.4    Bianchi, M.5    Sotgiu, M.L.6    Giagnoni, G.7
  • 41
    • 0141738711 scopus 로고    scopus 로고
    • Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats
    • Lim G, Sung B, Ji RR, Mao J. Upregulation of spinal cannabinoid-1- receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats. Pain. 2003;105(1-2):275-83.
    • (2003) Pain , vol.105 , Issue.1-2 , pp. 275-83
    • Lim, G.1    Sung, B.2    Ji, R.R.3    Mao, J.4
  • 42
    • 0035831179 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor upregulation in a rat model of chronic neuropathic pain
    • Siegling A, Hofmann HA, Denzer D, Mauler F, De Vry J. Cannabinoid CB1 receptor upregulation in a rat model of chronic neuropathic pain. Eur J Pharmacol. 2001;415(1):R5-7.
    • (2001) Eur J Pharmacol , vol.415 , Issue.1
    • Siegling, A.1    Hofmann, H.A.2    Denzer, D.3    Mauler, F.4    De Vry, J.5
  • 43
    • 33751244807 scopus 로고    scopus 로고
    • Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain
    • Mitrirattanakul S, Ramakul N, Guerrero AV, Matsuka Y, Ono T, Iwase H, Mackie K, Faull KF, Spigelman I. Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain. 2006;126(1-3):102-114
    • (2006) Pain , vol.126 , Issue.1-3 , pp. 102-114
    • Mitrirattanakul, S.1    Ramakul, N.2    Guerrero, A.V.3    Matsuka, Y.4    Ono, T.5    Iwase, H.6    Mackie, K.7    Faull, K.F.8    Spigelman, I.9
  • 44
    • 0017095185 scopus 로고
    • Clinical studies of cannabis tolerance and dependence
    • Jones RT, Benowitz N, Bachman J. Clinical studies of cannabis tolerance and dependence. Ann N Y Acad Sci. 1976;282:221-239
    • (1976) Ann N Y Acad Sci , vol.282 , pp. 221-239
    • Jones, R.T.1    Benowitz, N.2    Bachman, J.3
  • 45
    • 0033529223 scopus 로고    scopus 로고
    • The spinal biology in humans and animals of pain states generated by persistent small afferent input
    • Yaksh TL, Hua XY, Kalcheva I, Nozaki-Taguchi N, Marsala M. The spinal biology in humans and animals of pain states generated by persistent small afferent input. Proc Natl Acad Sci U S A. 1999;96:7680-7686
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7680-7686
    • Yaksh, T.L.1    Hua, X.Y.2    Kalcheva, I.3    Nozaki-Taguchi, N.4    Marsala, M.5
  • 46
    • 0038684167 scopus 로고    scopus 로고
    • Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models
    • Zhang J, Hoffert C, Vu HK, Groblewski T, Ahmad S, O'Donnell D. Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models. Eur J Neurosci. 2003;17(12):2750-2754
    • (2003) Eur J Neurosci , vol.17 , Issue.12 , pp. 2750-2754
    • Zhang, J.1    Hoffert, C.2    Vu, H.K.3    Groblewski, T.4    Ahmad, S.5    O'Donnell, D.6
  • 47
    • 0034951162 scopus 로고    scopus 로고
    • The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain
    • Bridges D, Ahmad K, Rice AS. The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain. Br J Pharmacol. 2001;133(4): 586-594
    • (2001) Br J Pharmacol , vol.133 , Issue.4 , pp. 586-594
    • Bridges, D.1    Ahmad, K.2    Rice, A.S.3
  • 48
    • 33751506126 scopus 로고    scopus 로고
    • Effects of a cannabinoid agonist on spinal nociceptive neurons in a rodent model of neuropathic pain
    • Liu C, Walker JM. Effects of a cannabinoid agonist on spinal nociceptive neurons in a rodent model of neuropathic pain. J Neurophysiol. 2006;96(6):2984-2994
    • (2006) J Neurophysiol , vol.96 , Issue.6 , pp. 2984-2994
    • Liu, C.1    Walker, J.M.2
  • 49
    • 0030915419 scopus 로고    scopus 로고
    • The development of morphine tolerance and dependence in rats with chronic pain
    • Yu W, Hao JX, Xu XJ, Wiesenfeld-Hallin Z. The development of morphine tolerance and dependence in rats with chronic pain. Brain Res. 1997;756(1-2):141-46.
    • (1997) Brain Res , vol.756 , Issue.1-2 , pp. 141-46
    • Yu, W.1    Hao, J.X.2    Xu, X.J.3    Wiesenfeld-Hallin, Z.4
  • 50
    • 0037176893 scopus 로고    scopus 로고
    • Effects of IV morphine in central pain: A randomized placebo-controlled study
    • Attal N, Guirimand F, Brasseur L, Gaude V, Chauvin M, Bouhassira D. Effects of IV morphine in central pain: a randomized placebo-controlled study. Neurology. 2002;58(4):554-563
    • (2002) Neurology , vol.58 , Issue.4 , pp. 554-563
    • Attal, N.1    Guirimand, F.2    Brasseur, L.3    Gaude, V.4    Chauvin, M.5    Bouhassira, D.6
  • 51
    • 0029077507 scopus 로고
    • Experimental mononeuropathy reduces the antinociceptive effects of morphine: Implications for common intracellular mechanisms involved in morphine tolerance and neuropathic pain
    • Mao J, Price DD, Mayer DJ. Experimental mononeuropathy reduces the antinociceptive effects of morphine: Implications for common intracellular mechanisms involved in morphine tolerance and neuropathic pain. Pain. 1995;61(3):353-64.
    • (1995) Pain , vol.61 , Issue.3 , pp. 353-64
    • Mao, J.1    Price, D.D.2    Mayer, D.J.3
  • 52
    • 0036784515 scopus 로고    scopus 로고
    • Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3- [(morpholinyl)methyl]pyrrolo [1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabinoid receptor adaptation in mice
    • Sim-Selley LJ, Martin BR. Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]-1,4- benzoxazinyl]-(1-naphthalenyl)methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabinoid receptor adaptation in mice. J Pharmacol Exp Ther. 2002;303(1):36-44.
    • (2002) J Pharmacol Exp Ther , vol.303 , Issue.1 , pp. 36-44
    • Sim-Selley, L.J.1    Martin, B.R.2
  • 53
    • 0036244709 scopus 로고    scopus 로고
    • Treatments for chronic pain associated with spinal cord injuries: Many are tried, few are helpful
    • Warms CA, Turner JA, Marshall HM, Cardenas DD. Treatments for chronic pain associated with spinal cord injuries: Many are tried, few are helpful. Clin J Pain. 2002;18(3):154-63.
    • (2002) Clin J Pain , vol.18 , Issue.3 , pp. 154-63
    • Warms, C.A.1    Turner, J.A.2    Marshall, H.M.3    Cardenas, D.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.