Synthesis and characterization studies of cisplatin/hydroxypropyl-β-cyclodextrin complex

Pharmacologyonline

Volumn 1, Issue , 2009, Pages 1135-1143

  Balaji, Anna ^a   Pandey, V P ^b   Srinath, M S ^c   Manavalan, R ^b  

^a Kumarswamy Layout   (India)

^b ANNAMALAI UNIVERSITY   (India)

^c CMR College of Pharmacy   (India)

Author keywords

Cisplatin; Cyclodextrin inclusion complex; Freeze drying; Hydroxypropyl cyclodextrin; Phase solubility; Stability constant

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; CISPLATIN DERIVATIVE;

AQUEOUS SOLUTION; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; FREEZE DRYING; INFRARED SPECTROMETRY; PHYSICAL CHEMISTRY;

EID: 65949106569     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Loehrer, P.J., Einhorn L.H. Drugs five years later. Cisplatin, Ann. Intern. Med. 1984;100:704-713.
2. Lehman, M., Thomas, G. Is concurrent chemotherapy and radiotherapy the new standard of care for locally advanced cervical cancer? Int. J. Gynecol. Cancer 2001;11:87-89.
3. Wagstaff, A.J., Ward, A., Benfield, P. and Heel R.C. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of cancer, Drugs. 1989;37:162-190.
4. Araki, H., Tani T., Kodama M. Antitumor effect of Cisplatin incorporated into polylactic acid microcapsules, Artif. Organs, 1999;23:161-168.
5. Wiltshaw E. Ovarian trials at Royal Marsden, Cancer Treat Rev. 1985;12:67-71.
6. Del Valle, E. M. M. Cyclodextrins and their uses: A review. Process Biochemistry 2004;39:1033-1046.
7. Rajewski, R.A., Stella, V.J. Pharmaceutical applications of cyclodextrins. 2. In vivo drug delivery. J. Pharm. Sci 1996;85:1142-1169.
8. Hedges, R. A. Industrial applications of cyclodextrins. Chem Rev, 1998;5:2035-2044
9. Szejtli J., 1988. Cyclodextrin Technology, Kluwer Academic Publishers, Boston, Dordrecht and The Netherlands 1988;39:188-192.
10. Alcaro S., Ventura C.A., Paolino D., Battaglia D., Ortuso F., Cattel L., Puglisi G., Fresta M. Preparation, characterization, molecular modeling and in vitro activity of paclitaxel-cyclodextrin complexes, Bioorg. Med. Chem. Lett. 2002;12: 1637-1641.
11. Higuchi T., Connors K. Phase solubility techniques, in: C. Reilly (Ed.), Advances in Analytical Chemistry and Instrumentation, Wiley/ Interscience, New York 1965:117-212.
12. Fromming K.H., Szejtli J. (Eds.). Cyclodextrin in Pharmacy, Kluwer Academic Publisher, Dordrecht 1994.
13. Andersson, A., Hedenmalm, H., Elfsson, B., Ehrsson, H. Determination of the acidic dissociation constant for cis - diammineaquachloroplatinum(II) ion. A hydrolysis product of Cisplatin. J Pharm Sci. 1994;83:859-862.
14. Connors K. A. The stability of Cyclodextrin complexes in solution, Chem Rev 1997;97:1325-58.
15. Lopez-Flores A, R. Jurado, P. Garcia-Lopez. A high-performance liquid chromatographic assay for determination of Cisplatin in plasma, cancer cell, and tumor samples, Journal of Pharmacological and Toxicological Methods 2005;52:366-372.