Size-controlled islet-cell spheroids for geometric analysis of insulin secretion

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

Volumn , Issue , 2009, Pages 423-426

  Tsuda, Y ^a,b   Kato Negishi, M ^a   Okitsu, T ^b,c   Takeuchi, S ^a,b,d  

^a INSTITUTE OF INDUSTRIAL SCIENCE   (Japan)

^b Ministry of Economy Trade and Industry   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d Japan Science and Technolog ^*  (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL LINES; CELL SPHEROIDS; GEOMETRIC ANALYSIS; IMMUNOCYTOCHEMISTRY; INSULIN SECRETION; INSULIN-DEPENDENT DIABETES MELLITUS; LIVE-CELL IMAGING; MICROWELLS; SHAPE-CONTROLLED; TRANSPLANTATION THERAPY;

CELL CULTURE; GLUCOSE; MEMS; MICROELECTROMECHANICAL DEVICES; SILICONES;

INSULIN;

EID: 65949103430     PISSN: 10846999     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/MEMSYS.2009.4805409     Document Type: Conference Paper

References (8)

1. M.J. Luther, E. Davies, D. Muller, M. Harrison, A.J. Bone, S.J. Persaud, P.M. Jones, "Cell-to-cell contact influences proliferative marker expression and apoptosis in MIN6 cells grown in islet-like structures", Am. J. Physiol. Endocrinol. Metab., Vol. 288, pp.E502- E509, 2005. (Pubitemid 40250544)
2. R. Lehmann, R.A. Zuellig, P. Kugelmeier, P.B. Baenninger, W. Moritz, A. Perren, P.A. Clavien, M. Weber, G.A. Spinas, "Superiority of small islets in human islet transplantation.", Diabetes. Vol. 56, pp.594-603, 2007. (Pubitemid 46348450)
3. J. Miyazaki, K. Araki, E. Yamato, H. Ikegami, T. Asano, Y. Shibasaki, Y. Oka, K. Yamamura,"Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms", Endocrinoloygy, Vol. 127, pp.126-132, 1990. (Pubitemid 20228111)
4. K. Minami, H. Yano, T. Miki, K. Nagashima, C.Z. Wang, H. Tanaka, J.I. Miyazaki, S. Seino, "Insulin secretion and differential gene expression in glucose-responsive and -unresponsive MIN6 suIblines.", Am. J. Physiol. Endocrinol. Metab., Vol. 279, pp. E773-E781, 2000.
5. T. Ibii, H. Shimada, S. Miura, E. Fukuma, H. Sato, H. Iwata, "Possibility of insulin-producing cells derived from mouse embryonic stem cells for diabetes treatment.", J. Biosci Bioeng., Vol. 103, pp. 140-146, 2007. (Pubitemid 46401492)
6. Y. Tsuda, A. Kikuchi, M. Yamato, G. Chen and T. Okano, "Heterotypic cell interactions on a dually patterned surface", Biochem. Biophys. Res. Comm., vol. 348, pp. 937-944, 2006. (Pubitemid 44233506)
7. K. lizuka, H. Nakajima, A. Ono, K. Okita, J. Miyazaki, J. Miyagawa, M. Namba, T. Hanafusa, Y. Matsuzawa, "Stable overexpression of the glucose-6-phosphatase catalytic subunit attenuates glucose sensitivity of insulin secretion from a mouse pancreatic beta-cell line.", J. Endocrinol., vol. 164, pp. 307-314, 2000. (Pubitemid 30163673)
8. A. Calabrese, M. Zhang, V. Serre-Beinier, D. Caton, C. Mas, "Connexin 36 controls synchronization of Ca2+ oscillations and insulin secretion in MIN6 cells", Diabetes, Vol. 52, pp. 417-424, 2003. (Pubitemid 36173198)