Cyclooxygenase 2 inhibition suppresses tubuloglomerular feedback: Roles of thromboxane receptors and nitric oxide

American Journal of Physiology - Renal Physiology

Volumn 296, Issue 4, 2009, Pages

  Araujo, Magali ^a   Welch, William J ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blood flow; Electrolyte homeostasis; Systemic volume

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; NEURONAL NITRIC OXIDE SYNTHASE; PARECOXIB; THROMBOXANE A2; THROMBOXANE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; DRUG DOSE REDUCTION; DRUG INHIBITION; FEEDBACK SYSTEM; GLOMERULUS FILTRATION RATE; HENLE LOOP; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULOGLOMERULAR FEEDBACK; MACULA DENSA; MALE; NEPHRON; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 65949102103     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.90446.2008     Document Type: Article

References (44)

1. Breyer MD, Breyer RM. Prostaglandin E receptors and the kidney. Am J Physiol Renal Physiol 279: F12-F23, 2000.
2. Breyer M, Davis L, Jacobson H, Breyer RM. Differential localization of prostaglandin E receptor subtypes in human kidney. Am J Physiol Renal Fluid Electrolyte Physiol 270: F912-F918, 1996. (Pubitemid 26178778)
3. Breyer MD, Jacobson HR, Davis LS, Breyer RM. In situ hybridization and localization of mRNA for the rabbit prostaglandin EP receptor. Kidney Int 43: 1372-1378, 1993.
4. Brian JE Jr, Faraci FM, Moore SA. COX-2-dependent delayed dilatation of cerebral arterioles in response to bradykinin. Am J Physiol Heart Circ Physiol 280: H2023-H2029, 2001.
5. Brown GP, Venuto RC. Thromboxane receptors in human kidney tissues. Prostaglandins Other Lipid Mediat 57: 179-188, 1999.
6. Cheng HF, Wang JL, Zhang MZ, McKanna JA, Harris RC. Role of p38 in the regulation of renal cortical cyclooxygenase-2 expression by extracellular chloride. J Clin Invest 106: 681-688, 2000.
7. Cheng HF, Zhang NZ, Harris RC. Nitric oxide stimulates cyclooxygenase-2 in cultured cTAL cells through a p38 dependent pathway. Am J Physiol Renal Physiol 290: F1391-F1397, 2006.
8. Cheng HF, Wang JL, Zhang MZ, McKanna JA, Harris RC. Nitric oxide regulates renal cortical cyclooxygenase-2 expression. Am J Physiol Renal Physiol 279: F122-F129, 2000.
9. Deng A, Wead LM, Blantz RC. Temporal adaptation of tubuloglomerular feedback: effects of COX-2. Kidney Int 66: 2348-2353, 2004. (Pubitemid 41115299)
10. Harris RC, McKanna JA, Akai Y, Jacobson HR, Dubois RN, Breyer MD. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest 94: 2504-2510, 1994. (Pubitemid 24379628)
11. Harris RC. COX-2 and the kidney. J Cardiovasc Pharmacol 47, Suppl 1: S37-S42, 2006.
12. Hartner A, Cordasic N, Goppelt-Struebe M, Veelken R, Hilgers KF. Role of macula densa cyclooxygenase-2 in renovascular hypertension. Am J Physiol Renal Physiol 284: F498-F502, 2003. (Pubitemid 36227910)
13. Ichihara A, Imig JD, Navar LG. Cyclooxygenase-2 modulates afferent arteriolar responses to increases in pressure. Hypertension 34: 843-847, 1999. (Pubitemid 29501310)
14. Ichihara A, Imig JD, Inscho EW, Navar LG. Cyclooxygenase-2 participates in tubular flow-dependent afferent arteriolar tone: interaction with neuronal NOS. Am J Physiol Renal Physiol 275: F605-F612, 1998. (Pubitemid 28491929)
15. Im JY, Kim D, Paik SG, Han PL. Cyclooxygenase-2-dependent neuronal death proceeds via superoxide anion generation. Free Radic Biol Med 41: 960-972, 2006. (Pubitemid 44247547)
16. Inscho E, Carmines P, Navar L. Prostaglandin influences on afferent arteriolar responses to vasoconstrictor agonists. Am J Physiol Renal Fluid Electrolyte Physiol 259: F157-F163, 1990. (Pubitemid 20246429)
17. Kammerl MC, Richthammer W, Kurtz A, Kramer BK. Angiotensin II feedback is a regulator of renocortical renin, COX-2, and nNOS expression. Am J Physiol Regul Integr Comp Physiol 282: R1613-R1617, 2002. (Pubitemid 34664485)
18. Kovacs G, Komlosi P, Fuson A, Peti-Peterdi J, Rosivall L, Bell PD. Neuronal nitric oxide synthase: its role and regulation in macula densa cells. J Am Soc Nephrol 14: 2475-2483, 2003. (Pubitemid 37169333)
19. Lash LH, Putt DA, Cai H. Drug metabolism enzyme expression and activity in primary cultures of human proximal tubular cells. Toxicology 244: 56-65, 2008. (Pubitemid 350299082)
20. Li J, Chen YJ, Quilley J. Effect of tempol on renal cyclooxygenase expression and activity in experimental diabetes in the rat. J Pharmacol Exp Ther 314: 818-824, 2005. (Pubitemid 40838990)
21. Mannon RB, Coffman TM, Mannon PJ. Distribution of binding sites for thromboxane A2 in the mouse kidney. Am J Physiol Renal Fluid Electrolyte Physiol 271: F1131-F1138, 1996.
22. Ollerstam A, Perrson EG. Macula densa neuronal nitric oxide synthase. Cardiovasc Res 56: 189-196, 2002. (Pubitemid 35223489)
23. Paliege A, Mizel D, Medina C, Pasumarthy A, Huang YG, Bachmann S, Briggs JP, Schnermann JB, Yang T. Inhibition of nNOS expression in the macula densa by COX-2-derived prostaglandin E2. Am J Physiol Renal Physiol 287: F152-F159, 2004. (Pubitemid 38780594)
24. Qi Z, Cai H, Morrow JD, Breyer MD. Differentiation of cyclooxygenase 1- and 2-derived prostanoids in mouse kidney and aorta. Hypertension 48: 323-328, 2006. (Pubitemid 44309830)
25. Schnermann J, Weber PC. Reversal of indomethacin-induced inhibition of tubuloglomerular feedback by prostaglandin infusion. Prostaglandins 24: 351-361, 1982. (Pubitemid 13216366)
26. Schnermann J, Traynor T, Pohl H, Thomas DW, Coffman TM, Briggs JP. Vasoconstrictor responses in thromboxane receptor knockout mice: tubuloglomerular feedback and uretheral obstruction. Acta Physiol Scand 168: 201-207, 2000. (Pubitemid 30128689)
27. Schweda F, Kammerl M, Wagner C, Kramer BK, Kurtz A. Upregulation of macula densa cyclooxygenase-2 expression is not dependent on glomerular filtration. Am J Physiol Renal Physiol 287: F95-F101, 2004. (Pubitemid 38780588)
28. Silldorff EP, Hilbun LR, Pallone TL. Angiotensin II constriction of rat vasa recta is partially thromboxane dependent. Hypertension 40: 541-546, 2002.
29. Takahashi N, Takeuchi K, Abe T, Sugawara A, Abe K. Immunolocalization of rats thromboxane receptor in the kidney. Endocrinology 137: 5170-5173, 1996. (Pubitemid 26403365)
30. Theilig F, Debiec H, Nafz B, Ronco P, Nusing R, Seyberth HW, Pavenstadt H, Bouby N, Bachmann S. Renal cortical regulation of COX-1 and functionally related products in early renovascular hypertension rat. Am J Physiol Renal Physiol 291: F987-F994, 2006.
31. Theilig F, Campean V, Paliege A, Breyer M, Briggs JP, Schnermann J, Bachmann S. Epithelial COX-2 expression is not regulated by nitric oxide in rodent cortex. Hypertension 39: 848-853, 2002.
32. Thorup C, Sundler F, Ekblad E, Persson EG. Resetting of the tubuloglomerular feedback mechanism by blockade of NO synthase. Acta Physiol Scand 148: 359-360, 1993.
33. Villegas I, Martin MJ, La Casa C, Motilva V, De La Lastra CA. Effects of oxicam inhibitors of cyclooxygenase on oxidative stress generation in rat gastric mucosa. A comparative study. Free Radic Res 36: 769-777, 2002. (Pubitemid 34746303)
34. Virdis A, Colucci R, Fornai M, Blandizzi C, Duranti E, Pinto S, Bernardini N, Segnani C, Antonioli L, Taddei S, Salvetti A, Del Tacca M. Cyclooxygenase-2 inhibition improves vascular endothelial dysfunction in a rat model of endotoxic shock: role of inducible nitric oxide synthase and oxidative stress. J Pharmacol Exp Ther 312: 945-953, 2005. (Pubitemid 40293752)
35. Welch WJ. Effects of isoprostanes on tubuloglomerular feedback: roles for TP receptors, NOS and salt intake. Am J Physiol Renal Physiol 288: F757-F762, 2005.
36. Welch WJ, Wilcox CS. Potentiation of tubuloglomerular feedback in the rat by thromboxane mimetic: role of macula densa. J Clin Invest 89: 1857-1865, 1992.
37. 2/PGH2 receptor expression and TGF response to U-46,619. Am J Physiol Renal Physiol 273: F976-F983, 1997.
38. Wilcox CS, Welch WJ, Schmidt HHHW, Murad F, Gross SS, Taylor G, Levi R. Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci USA 89: 11993-11997, 1992. (Pubitemid 23004771)
39. Wilcox CS, Welch WJ, Snellen H. Thromboxane mediates renal hemodynamic response to infused angiotensin II. Kidney Int 40: 1090-1097, 1991.
40. Wilcox CS, Welch WJ. Thromboxane synthase and TP receptor mRNA in rat kidney and brain: effects of salt intake and ANG II. Am J Physiol Renal Physiol 284: F525-F531, 2003.
41. Winters CJ, Reeves WB, Andreoli TE. A survey of transport properties of the thick ascending limb. Semin Nephrol 11: 236-247, 1991.
42. Yabuki A, Tahara T, Taniguchi K, Matsumoto M, Suzuki S. Neuronal nitric oxide synthase and cyclooxygenase-2 in diabetic nephropathy of type 2 diabetic OLETF rats. Exp Anim 55: 17-25, 2006. (Pubitemid 43349427)
43. Yao B, Xu J, Qi Z, Harris RC, Zhang MZ. Role of renal cortical cyclooxygenase-2 expression in hyperfiltration in rats with high-protein intake. Am J Physiol Renal Physiol 291: F368-F373, 2006. (Pubitemid 44148127)
44. Zhang HQ, Fast W, Marletta MA, Martasek P, Silverman RB. Potent and selective inhibition of neuronal nitric oxide synthase by N-ω-propyl L-arginine. J Med Chem 40: 3869-3870, 1997.