Intracellular adenosine triphosphate delivery enhanced skin wound healing in rabbits

Annals of Plastic Surgery

Volumn 62, Issue 2, 2009, Pages 180-186

  Wang, Jianpu ^a,b   Zhang, Qunwei ^a   Wan, Rong ^a   Mo, Yiqun ^a   Li, Ming ^a   Tseng, Michael T ^a   Chien, Sufan ^a  

^a University of Louisville School of Medicine   (United States)

^b MDR 325 ^*  (United States)

Author keywords

ATP; Ischemia; Rabbit; Wound healing

Indexed keywords

ADENOSINE TRIPHOSPHATE; CD31 ANTIGEN; POLYURETHAN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EAR; EPITHELIZATION; HISTOLOGY; ISCHEMIA; MINIMALLY INVASIVE SURGERY; NONHUMAN; PRIORITY JOURNAL; RABBIT; SKIN INJURY; TISSUE GROWTH; TREATMENT DURATION; WOUND DRESSING; WOUND HEALING;

ADENOSINE TRIPHOSPHATE; ANIMALS; INTRACELLULAR SPACE; RABBITS; SKIN; WOUND HEALING;

EID: 65949098637     PISSN: 01487043     EISSN: None     Source Type: Journal    
DOI: 10.1097/SAP.0b013e31817fe47e     Document Type: Article

References (38)

1. Liechty KW, Sablich TJ, Adzick NS, et al. Recombinant adenoviral mediated gene transfer in ischemic impaired wound healing. Wound Repair Regen. 1999;7:148-153.
2. Strecker-McGraw MK, Jones TR, Baer DG. Soft tissue wounds and principles of healing. Emerg Med Clin North Am. 2007;25:1-22.
3. Page JC. Critiquing clinical research of new technologies for diabetic foot wound management. J Foot Ankle Surg. 2002;41:251-259.
4. Ehrlich HP, Grislis G, Hunt TK. Metabolic and circulatory contributions to oxygen gradients in wounds. Surgery. 1972;72:578-583.
5. Im MJ, Hoopes JE. Energy metabolism in healing skin wounds. J Surg Res. 1970;10:459-464.
6. Wang DJ, Huang NN, Heppel LA. Extracellular ATP shows synergistic enhancement of DNA synthesis when combined with agents that are active in wound healing or as neurotransmitters. Biochem Biophys Res Commun. 1990;166:251-258.
7. Chien S. Intracellular ATP delivery using highly fusogenic liposomes. Meth Molecular Biol. 2009 [In press].
8. Chiang B, Essick E, Ehringer W, et al. Enhancing skin wound healing by direct delivery of intracellular adenosine triphosphate. Am J Surg. 2007;193: 213-218.
9. Lindblad WJ. How should one study wound healing? Wound Repair Regen. 2006;14:515.
10. Chien S. Ischemic rabbit ear model created by minimally invasive surgery. Wound Repair Regen. 2007;15:928-935.
11. Cartwright L, Farhat WA, Sherman C, et al. Dynamic contrast-enhanced MRI to quantify VEGF-enhanced tissue-engineered bladder graft neovasculariza-tion: pilot study. J Biomed Mater Res. 2006;77:390-395.
12. Jones M, Clayton E, Noel C, et al. Immunohistochemical endothelial localisation-a novel method of vessel delineation in tendon tissue. J Immunol Methods. 2003;280:175-181.
13. Mall JW, Schwenk W, Philipp AW, et al. Intraperitoneal administration of the angiogenesis inhibitor thalidomide does not impair anastomotic healing following large bowel resection in a rabbit model. World J Surg. 2003;27: 1119-1123.
14. Schaffer M, Witte M, Becker HD. Models to study ischemia in chronic wounds. Int J Lower Extremity Wounds. 2002;1:104-111.
15. Silver I. The physiology of wound healing. In: Hunt T, ed. Wound Healing and Wound Infection Theory and Surgical Practice. New York: Appleton; 1980:11-31.
16. Smith DG, Mills WJ, Steen RG, et al. Levels of high energy phosphate in the dorsal skin of the foot in normal and diabetic adults: the role of 31P magnetic resonance spectroscopy and direct quantification with high pressure liquid chromatography. Foot Ankle Int. 1999;20:258-262.
17. Fine N, Mustoe T, eds. Wound Healing. Philadelphia: Lippincott; 2001.
18. Hunt TK, Pai MP. The effect of varying ambient oxygen tensions on wound metabolism and collagen synthesis. Surg Gynecol Obstet. 1972;135:561-567.
19. Stadelmann WK, Digenis AG, Tobin GR. Impediments to wound healing. Am J Surg. 1998;176:39S-47S.
20. Gottrup F. Oxygen, wound healing and the development of infection. Present status. Eur J Surg Acta Chirurgica. 2002;168:260-263.
21. Pai MP, Hunt TK. Effect of varying oxygen tensions on healing of open wounds. Surg Gynecol Obstet. 1972;135:756-758.
22. Wang C, Schwaitzberg S, Berliner E, et al. Hyperbaric oxygen for treating wounds: a systematic review of the literature. Arch Surg. 2003;138:272-279; discussion 280.
23. Manning AM. Oxygen therapy and toxicity. Vet Clinics North Am. 2002;32: 1005-1020.
24. Niinikoski J. Hyperbaric oxygen therapy of diabetic foot ulcers, transcutane-ous oxymetry in clinical decision making. Wound Repair Regen. 2003;11: 458-461.
25. Almskog BA, Haljamae H, Hasselgren PO, et al. Local metabolic changes in skeletal muscle following high-energy missile injury. J Trauma. 1982;22: 382-387.
26. Kristensen SR. A critical appraisal of the association between energy charge and cell damage. Biochim Biophys Acta. 1989;1012:272-278.
27. Taegtmeyer H. Energy metabolism of the heart: from basic concepts to clinical applications. Curr Probl Cardiol. 1994;19:59-113.
28. Gabizon AA. Stealth liposomes and tumor targeting: one step further in the quest for the magic bullet. Clin Cancer Res. 2001;7:223-225.
29. Chien S. Metabolic management. In: Toledo-Pereyra L, ed. Organ Procurement and Preservation for Transplantation. 3rd edition, New York: Landes Bio-science. Springer; 2008;1-42. Available at http://eurekah.com/ chaoter/3992.
30. Witte MB, Barbul A. General principles of wound healing. Surg Clinics North Am. 1997;77:509-528.
31. Harding KG, Morris HL, Patel GK. Science, medicine and the future: healing chronic wounds. BMJ. 2002;324:160-163.
32. Brem H, Tomic-Canic M. Cellular and molecular basis of wound healing in diabetes. J Clin Invest. 2007;117:1219-1222.
33. Falanga V. Growth factors and wound healing. Dermatol Clin. 1993;11:667-675.
34. Falanga V. Growth factors and wound healing. J Dermatol Surg Oncol. 1993;19:711-714.
35. Nanney LB, Caldwell RL, Pollins AC, et al. Novel approaches for understanding the mechanisms of wound repair. J Investig Dermatol Symp Proc. 2006;11:132-139.
36. Sauer H, Bekhite MM, Hescheler J, et al. Redox control of angiogenic factors and CD31-positive vessel-like structures in mouse embryonic stem cells after direct current electrical field stimulation. Exp Cell Res. 2005;304:380-390.
37. Yancopoulos GD, Davis S, Gale NW, et al. Vascular-specific growth factors and blood vessel formation. Nature. 2000;407:242-248.
38. Nwomeh BC, Yager DR, Cohen IK. Physiology of the chronic wound. Clin Plast Surg. 1998;25:341-356.