The unfolded protein response contributes to preimplantation mouse embryo death in the DDK syndrome

Biology of Reproduction

Volumn 80, Issue 5, 2009, Pages 944-953

  Hao, Lanping ^a   Vassena, Rita ^a,b   Wu, Guangming ^a,c   Han, Zhiming ^a   Cheng, Yong ^a   Latham, Keith E ^a   Sapienza, Carmen ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Centre de Medicina Regenerativa de Barcelona   (Spain)

^c MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

Author keywords

DDK syndrome; Early development; Embryo; Epigenetics; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; GENE PRODUCT; GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 5; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; C57BL 6 MOUSE; CELL CYCLE; CELL TRANSFORMATION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CROSS BREEDING; DDK SYNDROME; EMBRYO; EMBRYO DEATH; ENDOPLASMIC RETICULUM; FEMALE; GENE LOCUS; GENETIC INCOMPATIBILITY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MICROARRAY ANALYSIS; MORULA; MOUSE; MOUSE STRAIN; NONHUMAN; OOCYTE; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; BASE SEQUENCE; CROSSES, GENETIC; DNA PRIMERS; EMBRYO LOSS; EMBRYONIC DEVELOPMENT; ENDOPLASMIC RETICULUM; FEMALE; GENE EXPRESSION PROFILING; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MORULA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREGNANCY; PROTEIN FOLDING; RNA, MESSENGER; STRESS, PHYSIOLOGICAL; SYNDROME;

MUS;

EID: 65949093026     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.108.072546     Document Type: Article

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