α2-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the l-arginine/nitric oxide/cyclic GMP pathway in rat

European Journal of Pharmacology

Volumn 613, Issue 1-3, 2009, Pages 64-67

  Romero, Thiago R L ^a   Duarte, Igor D G ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

2 Adrenoceptor; Cyclic GMP; Nitric oxide; Peripheral antinociception; Xylazine

Indexed keywords

ARGININE; CYCLIC GMP; NITRIC OXIDE; XYLAZINE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HYPERALGESIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALGESICS; ANIMALS; ARGININE; CYCLIC GMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GUANYLATE CYCLASE; HYPERALGESIA; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHORIC DIESTER HYDROLASES; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; XYLAZINE;

EID: 65949085163     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.04.031     Document Type: Article

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