Association between renin-angiotensin-aldosterone system genotypes and haplotypes and risk of ischemic stroke of atherosclerotic etiology

Acta Neurologica Scandinavica

Volumn 119, Issue 6, 2009, Pages 356-363

  Saidi, S ^a   Mallat, S G ^b   Almawi, W Y ^c   Mahjoub, T ^a  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b SAINT JOSEPH UNIVERSITY   (Lebanon)

^c ARABIAN GULF UNIVERSITY   (Bahrain)

Author keywords

Angiotensinogen; polymorphism; renin; stroke

Indexed keywords

ADULT; ALLELE; ARTICLE; ATHEROSCLEROSIS; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; TUNISIA;

ANGIOTENSINOGEN; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; INTRACRANIAL ARTERIOSCLEROSIS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RENIN; RENIN-ANGIOTENSIN SYSTEM; RISK FACTORS; STROKE; TUNISIA;

EID: 65749088723     PISSN: 00016314     EISSN: 16000404     Source Type: Journal    
DOI: 10.1111/j.1600-0404.2008.01105.x     Document Type: Article

References (39)

1. Gao X, Yang H, Zhiping T. Association studies of genetic polymorphism, environmental factors and their interaction in ischemic stroke. Neurosci Lett 2006 398 : 172 7. (Pubitemid 43673708)
2. Hassan A, Markus HS. Genetics and ischemic stroke. Brain 2000 123 : 1784 812.
3. Ariyaratnam R, Casas JP, Whittaker J, Smeeth L, Hingorani AD, Sharma P. Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals. PLoS Med 2007 4 : e131. (Pubitemid 46658774)
4. Banerjee I, Gupta V, Ganesh S. Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis. J Hum Genet 2007 52 : 205 19. (Pubitemid 46318941)
5. Kiely DK, Wolf PA, Cupples LA, Beiser AS, Meyers RH. Familial aggregation of stroke: the Framingham study. Stroke 1993 24 : 1366 71. (Pubitemid 23254641)
6. Liao D, Myers R, Hunt S et al. Familial history of stroke and stroke risk: the Family Heart Study. Stroke 1997 28 : 1908 12. (Pubitemid 27458994)
7. Szolnoki Z. Evaluation of the interactions of common genetic mutations in stroke. Methods Mol Med 2005 104 : 241 50.
8. Zhang JH, Kohara K, Yamamoto Y et al. Genetic predisposition to neurological symptoms in lacunar infarction. Cerebrovasc Dis 2004 17 : 273 9. (Pubitemid 38621540)
9. Szolnoki Z, Havasi V, Talián G et al. Angiotensin II type-1 receptor A1166C polymorphism is associated with increased risk of ischemic stroke in hypertensive smokers. J Mol Neurosci 2006 28 : 285 90. (Pubitemid 43780321)
10. Um JY, Moon KS, Lee KM et al. Polymorphism of angiotensin-converting enzyme, angiotensinogen, and apolipoprotein E genes in Korean patients with cerebral infarction. J Mol Neurosci 2003 21 : 23 8.
11. Schiavon R, Turazzini M, De Fanti E et al. PON1 activity and genotype in patients with arterial ischemic stroke and in healthy individuals. Acta Neurol Scand 2007 116 : 26 30. (Pubitemid 46976264)
12. Shin BS, Oh SY, Kim YS, Kim KW. The paraoxonase gene polymorphism in stroke patients and lipid profile. Acta Neurol Scand 2008 117 : 237 43.
13. Jeunemaitre X, Soubrier F, Kotelevtsev YV et al. Molecular basis of human hypertension: role of angiotensinogen. Cell 1992 71 : 169 80.
14. Klungel OH, Kaplan RC, Heckbert SR et al. Control of blood pressure and risk of stroke among pharmacologically treated hypertensive patients. Stroke 2000 31 : 420 4. (Pubitemid 30078176)
15. Van RIJNMJ, Bos MJ, Isaacs A et al. Polymorphisms of the renin-angiotensin system are associated with blood pressure, atherosclerosis and cerebral white matter pathology. J Neurol Neurosurg Psychiatry 2007 78 : 1083 7.
16. Inoue I, Nakajima T, Williams CS et al. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest 1997 99 : 1786 97. (Pubitemid 27164639)
17. Nakase T, Mizuno T, Harada S et al. Angiotensinogen gene polymorphism as a risk factor for ischemic stroke. J Clin Neurosci 2007 14 : 943 7. (Pubitemid 47334955)
18. Rubattu S, Di Angelantonio E, Stanzione R et al. Gene polymorphisms of the renin-angiotensin-aldosterone system and the risk of ischemic stroke: a role of the A1166C-AT1 gene variant. J Hypertens 2004 22 : 2129 34. (Pubitemid 39463806)
19. Szolnoki Z. Pathomechanism of leukoaraiosis: a molecular bridge between the genetic, biochemical, and clinical processes (a mitochondrial hypothesis). Neuromolecular Med. 2007 9 : 21 34.
20. Slowik A, Turaj W, Dziedzic T et al. DD genotype of ACE gene is a risk factor for intracerebral hemorrhage. Neurology 2004 63 : 359 61. (Pubitemid 38971144)
21. Makino Y, Kawano Y, Minami J, Yamaguchi T, Takishita S. Risk of stroke in relation to level of blood pressure and other risk factors in treated hypertensive patients. Stroke 2000 31 : 48 52. (Pubitemid 30035751)
22. Pojoga L, Gautier S, Blanc H et al. Genetic determination of plasma aldosterone levels in essential hypertension. Am J Hypertens 1998 11 : 856 60. (Pubitemid 28351020)
23. Böhm M. Angiotensin receptor blockers versus angiotensin-converting enzyme inhibitors: where do we stand now? Am J Cardiol 2007 100 : 38J 44J.
24. Jeunemaitre X, Inoue I, Williams C et al. Haplotypes of angiotensinogen in essential hypertension. Am J Hum Genet 1997 60 : 1448 60. (Pubitemid 27258077)
25. Girerd X, Hanon O, Mourad JJ, Boutouyrie P, Laurent S, Jeunemaitre X. Lack of association between renin-angiotensin system, gene polymorphisms, and wall thickness of the radial and carotid arteries. Hypertension 1998 32 : 579 83. (Pubitemid 28429153)
26. Goldenberg I, Moss AJ, Ryan D, Mcnitt S, Eberly SW, Zareba W. Polymorphism in the angiotensinogen gene, hypertension, and ethnic differences in the risk of recurrent coronary events. Hypertension 2006 48 : 693 9.
27. Mansego ML, Redon J, Marin R et al. Renin polymorphisms and haplotypes are associated with blood pressure levels and hypertension risk in postmenopausal women. J Hypertens 2008 26 : 230 7.
28. Kostulas K, Brophy VH, Moraitis K et al. Genetic profile of ischemic cerebrovascular disease and carotid stenosis. Acta Neurol Scand 2008 118 : 146 52.
29. Gormley K, Bevan S, Markus HS. Polymorphisms in genes of the renin-angiotensin system and cerebral small vessel disease. Cerebrovasc Dis 2007 23 : 148 55. (Pubitemid 46239155)
30. Marciante KD, Bis JC, Rieder MJ et al. Renin-angiotensin system haplotypes and the risk of myocardial infarction and stroke in pharmacologically treated hypertensive patients. Am J Epidemiol 2007 166 : 19 27. (Pubitemid 47234299)
31. Sethi AA, Nordestgaard BG, Grønholdt ML, Steffensen R, Jensen G, Tybjaerg-Hansen A. Angiotensinogen single nucleotide polymorphisms, elevated blood pressure, and risk of cardiovascular disease. Hypertension 2003 41 : 1202 11. (Pubitemid 36706066)
32. Mondry A, Loh M, Liu P, Zhu AL, Nagel M. Polymorphisms of the insertion-deletion ACE and M235T AGT genes and hypertension: surprising new findings and meta-analysis of data. BMC Nephrol 2005 6 : 1. (Pubitemid 40317991)
33. Brenner D, Labreuche J, Poirier O, Cambien F, Amarenco P, GENIC INVESTIGATORS. Renin-angiotensin-aldosterone system in brain infarction and vascular death. Ann Neurol 2005 58 : 131 8. (Pubitemid 40962468)
34. Kamitani A, Rakugi H, Higaki J et al. Enhanced predictability of myocardial infarction in Japanese by combined genotype analysis. Hypertension 1995 25 : 950 3.
35. Glavnik N, Petrovic D. M235T polymorphism of the angiotensinogen gene and insertion-deletion polymorphism of the angiotensin-1 converting enzyme gene in essential arterial hypertension in Caucasians. Folia Biol (Praha) 2007 53 : 69 70. (Pubitemid 46546781)
36. Onipinla AK, Barley J, Carter ND, Macgregor GA, Sagnella GA. Relationship between the M235T and G(-6)A polymorphisms of the angiotensinogen gene. J Hum Hypertens 1999 13: 865 6. (Pubitemid 30028955)
37. Rotimi C, Puras A, Cooper R et al. Polymorphisms of renin-angiotensin genes among Nigerians, Jamaicans, and African Americans. Hypertension 1996 27 : 558 63. (Pubitemid 26086224)
38. Agachan B, Isbir T, Yilmaz H, Akoglu E. Angiotensin converting enzyme I-D, angiotensin T174M-M235T and angiotensin II type 1 receptor A1166C gene polymorphisms in Turkish hypertensive patients. Exp Mol Med 2003 35 : 545 9. (Pubitemid 38129319)
39. Sethi AA, Tybjaerg-Hansen A, Grønholdt ML, Steffensen R, Schnohr P, Nordestgaard BG. Angiotensinogen mutations and risk for ischemic heart disease, myocardial infarction, and ischemic cerebrovascular disease. Six case-control studies from the Copenhagen City Heart Study. Ann Intern Med 2001 134 : 941 54.