-
1
-
-
33845631591
-
Aspects of genetic susceptibility to human infectious diseases
-
DOI 10.1146/annurev.genet.40.110405.090546
-
Hill, A. V. (2006) Aspect of genetic susceptibility to human diseases. Annu. Rev. Genet. 40: 469-86 (Pubitemid 44956793)
-
(2006)
Annual Review of Genetics
, vol.40
, pp. 469-486
-
-
Hill, A.V.S.1
-
2
-
-
0012929728
-
Tolllike receptors
-
Takeda, K., Kaisho, T., Akira, S. (2003) Tolllike receptors. Annu. Rev. Immunol. 21: 335-76.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 335-376
-
-
Takeda, K.1
Kaisho, T.2
Akira, S.3
-
3
-
-
0036355461
-
Automated genotyping using the DNA MassArray technology
-
Jurinke, C., van den Boom, D., Cantor, C. R., Koster, H. (2002) Automated genotyping using the DNA MassArray technology. Methods Mol. Biol. 187: 179-92.
-
(2002)
Methods Mol. Biol.
, vol.187
, pp. 179-192
-
-
Jurinke, C.1
Van Den Boom, D.2
Cantor, C.R.3
Koster, H.4
-
4
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
DOI 10.1126/science.282.5396.2085
-
Poltorak, A., He, X., Smirnova, I., Liu, M.Y., Van Huffel, C., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., Freudenberg, M., Ric-ciardi-Castagnoli, P., Layton, B., Beutler, B. (1998) Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 282: 2085-8. (Pubitemid 29001265)
-
(1998)
Science
, vol.282
, Issue.5396
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.-Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
Layton, B.13
Beutler, B.14
-
5
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide evidence for TLR4 as the Lps gene product
-
Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K., Akira, S. (1999) Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162: 3749-52 (Pubitemid 29314747)
-
(1999)
Journal of Immunology
, vol.162
, Issue.7
, pp. 3749-3752
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
Takeda, Y.6
Takeda, K.7
Akira, S.8
-
6
-
-
0037947560
-
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
-
DOI 10.1073/pnas.1031605100
-
Smirnova, I., Mann, N., Dols, A., Derkx, H.H, Hibberd, M.L., Levin, M., Beutler, B. (2003) Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningo-coccal susceptibility. Proc. Natl. Acad. Sci. U. S. A. 100: 6075-80. (Pubitemid 36576933)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.10
, pp. 6075-6080
-
-
Smirnova, I.1
Mann, N.2
Dols, A.3
Derkx, H.H.4
Hibberd, M.L.5
Levin, M.6
Beutler, B.7
-
7
-
-
10744226016
-
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease
-
DOI 10.1084/jem.20031220
-
Hawn, T.R., Verbon, A., Lettinga, K.D., Zhao, L.P., Li, S.S., Laws, R.J., Skerrett, S. J., Beutler, B., Schroeder, L., Nachman, A., Ozin-sky, A., Smith, K.D., Aderem, A. (2003) A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J. Exp. Med. 198: 1563-72. (Pubitemid 37467170)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.10
, pp. 1563-1572
-
-
Hawn, T.R.1
Verbon, A.2
Lettinga, K.D.3
Zhao, L.P.4
Li, S.S.5
Laws, R.J.6
Skerrett, S.J.7
Beutler, B.8
Schroeder, L.9
Nachman, A.10
Ozinsky, A.11
Smith, K.D.12
Aderem, A.13
-
8
-
-
14044259411
-
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
-
DOI 10.1073/pnas.0409831102
-
Hawn, T.R., Verbon, A., Janer, M., Zhao, L.P., Beutler, B., Aderem, A. (2005) Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc. Natl. Acad. Sci. U. S. A. 102: 2487-9. (Pubitemid 40279403)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.7
, pp. 2487-2489
-
-
Hawn, T.R.1
Verbon, A.2
Janer, M.3
Zhao, L.P.4
Beutler, B.5
Aderem, A.6
-
9
-
-
13444280215
-
CD36 is a sensor of diacylglycerides
-
DOI 10.1038/nature03253
-
Hoebe, K., Georgel, P., Rutschmann, S., Du, X., Mudd, S., Crozat, K., Sovath, S., Shamel, L., Hartung, T., Zahringer, U., Beutler, B. (2005) CD36 is a sensor of diacylglycerides. Nature 433: 523-7. (Pubitemid 40204309)
-
(2005)
Nature
, vol.433
, Issue.7025
, pp. 523-527
-
-
Hoebe, K.1
Georgel, P.2
Rutschmann, S.3
Du, X.4
Mudd, S.5
Crozat, K.6
Sovath, S.7
Shamel, L.8
Hartung, T.9
Zahringer, U.10
Beutler, B.11
-
10
-
-
34047098731
-
A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis
-
Khor, C.C., Chapman, S.J., Vannberg, F.O., Dunne, A., Murphy, C., Ling, E.Y., Frodsham, A.J., Walley, A.J., Kyrieleis, O., Khan, A., Aucan, C., Segal, S., Moore, C.E., Knox, K., Campbell, S.J., Lienhardt, C., Scott, A., Aaby, P., Sow, O.Y., Grignani, R.T., Sillah, J., Sirugo, G., Peshu, N., Williams, T.N., Maitland, K., Davies, R.J., Kwiatkowski, D.P., Day, N.P., Yala, D., Crook, D.W., Marsh, K., Berkley, J.A., O'Neill, L.A., Hill, A.V. (2007) A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nat. Genet. 39: 523-38
-
(2007)
Nat. Genet.
, vol.39
, pp. 523-538
-
-
Khor, C.C.1
Chapman, S.J.2
Vannberg, F.O.3
Dunne, A.4
Murphy, C.5
Ling, E.Y.6
Frodsham, A.J.7
Walley, A.J.8
Kyrieleis, O.9
Khan, A.10
Aucan, C.11
Segal, S.12
Moore, C.E.13
Knox, K.14
Campbell, S.J.15
Lienhardt, C.16
Scott, A.17
Aaby, P.18
Sow, O.Y.19
Grignani, R.T.20
Sillah, J.21
Sirugo, G.22
Peshu, N.23
Williams, T.N.24
Maitland, K.25
Davies, R.J.26
Kwiatkowski, D.P.27
Day, N.P.28
Yala, D.29
Crook, D.W.30
Marsh, K.31
Berkley, J.A.32
O'Neill, L.A.33
Hill, A.V.34
more..
-
11
-
-
14844337835
-
Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: Cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity
-
DOI 10.1074/jbc.M413541200
-
Krishnegowda, G., Hajjar, A.M., Zhu, J., Douglass, E.J., Uematsu, S., Akira, S., Woods, A.S., Gowda, D.C. (2005) Induction of proin-flammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signalling receptors, glycosyl-phosphatidylinositol (GPI) structural requirement, and regulation of GPI activity. J. Biol. Chem. 280: 8606-16. (Pubitemid 40349765)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.9
, pp. 8606-8616
-
-
Krishnegowda, G.1
Hajjar, A.M.2
Zhu, J.3
Douglass, E.J.4
Uematsu, S.5
Akira, S.6
Woods, A.S.7
Gowda, D.C.8
-
12
-
-
16744364738
-
Structural Complementarity of Toll/Interleukin-1 Receptor Domains in Toll-like Receptors and the Adaptors Mal and MyD88
-
DOI 10.1074/jbc.M301742200
-
Dunne, A., Ejdeback, M., Ludidi, P.L., O'Neill, L.A., Gay, N.J. (2003) Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors TIRAP and MyD88. J. Biol. Chem. 278: 41443-51 (Pubitemid 37280973)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.42
, pp. 41443-41451
-
-
Dunne, A.1
Ejdeback, M.2
Ludidi, P.L.3
O'Neill, L.A.J.4
Gay, N.J.5
-
13
-
-
0035936836
-
Induction of direct antimicrobial activity through mammalian toll-like receptors
-
DOI 10.1126/science.291.5508.1544
-
Thoma-Uszynski, S., Stenger, S., Takeuchi, O., Ochoa, M.T., Engele, M., Sieling, P.A., Barnes, P. F., Rollinghoff, M., Bolcskei, P.L., Wagner, M., Akira, S., Norgard, M.V., Belisle, J.T., Godowski, P.J., Bloom, B.R., Modlin, R.L. (2001) Induction of direct antimicrobial activity through mammalian toll-like receptors. Science 291: 1544-7. (Pubitemid 32179220)
-
(2001)
Science
, vol.291
, Issue.5508
, pp. 1544-1547
-
-
Thoma-Uszynski, S.1
Stenger, S.2
Takeuchi, O.3
Ochoa, M.T.4
Engele, M.5
Sieling, P.A.6
Barnes, P.F.7
Rollinghoff, M.8
Bolcskei, P.L.9
Wagner, M.10
Akira, S.11
Norgard, M.V.12
Belisle, J.T.13
Godowski, P.J.14
Bloom, B.R.15
Modlin, R.L.16
|