Generation of an ABCG2GFPn-puro transgenic line - A tool to study ABCG2 expression in mice

Biochemical and Biophysical Research Communications

Volumn 384, Issue 2, 2009, Pages 199-203

  Orford, Michael ^a   Mean, Richard ^a   Lapathitis, George ^a   Genethliou, Nicholas ^a   Panayiotou, Elena ^a   Panayi, Helen ^a   Malas, Stavros ^a,b  

^a CYPRUS INSTITUTE OF NEUROLOGY AND GENETICS   (Cyprus)

^b UNIVERSITY OF CYPRUS   (Cyprus)

Author keywords

ABCG2; Choroid plexus; Endothelial cells; Transgenic mice

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; GREEN FLUORESCENT PROTEIN; PUROMYCIN;

ANIMAL CELL; ARTICLE; BRAIN DEVELOPMENT; CELL ISOLATION; EMBRYO; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; ENHANCER REGION; FOREBRAIN; MOUSE; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SPINAL CORD;

ALLELES; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ATP-BINDING CASSETTE TRANSPORTERS; BRAIN; CELL NUCLEUS; DRUG RESISTANCE, NEOPLASM; ENHANCER ELEMENTS, GENETIC; GREEN FLUORESCENT PROTEINS; MICE; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; PUROMYCIN;

MUS; MUS MUSCULUS;

EID: 65649145187     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.04.089     Document Type: Article

References (31)

1. Zhou S., Schuetz J.D., Bunting K.D., Colapietro A.M., Sampath J., Morris J.J., Lagutina I., Grosveld G.C., Osawa M., Nakauchi H., and Sorrentino B.P. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat. Med. 7 (2001) 1028-1034
2. Zhou S., Morris J.J., Barnes Y., Lan L., Schuetz J.D., and Sorrentino B.P. Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Proc. Natl. Acad. Sci. USA 99 (2002) 12339-12344
3. Wu C., and Alman B.A. Side population cells in human cancers. Cancer Lett. 268 (2008) 1-9
4. Bleau A.M., Hambardzumyan D., Ozawa T., Fomchenko E.I., Huse J.T., Brennan C.W., and Holland E.C. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 4 (2009) 226-235
5. Polgar O., Robey R.W., and Bates S.E. ABCG2: structure, function and role in drug response. Expert Opin. Drug Metab. Toxicol. 4 (2008) 1-15
6. Mouthon M.A., Fouchet P., Mathieu C., Sii-Felice K., Etienne O., Lages C.S., and Boussin F.D. Neural stem cells from mouse forebrain are contained in a population distinct from the 'side population'. J. Neurochem. 99 (2006) 807-817
7. Tachikawa M., Watanabe M., Hori S., Fukaya M., Ohtsuki S., Asashima T., and Terasaki T. Distinct spatio-temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain. J. Neurochem. 95 (2005) 294-304
8. Zhang Y., Buchholz F., Muyrers J.P., and Stewart A.F. A new logic for DNA engineering using recombination in Escherichia coli. Nat. Genet. 20 (1998) 123-128
9. Hallmann R., Mayer D.N., Berg E.L., Broermann R., and Butcher E.C. Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood-brain barrier. Dev. Dyn. 202 (1995) 325-332
10. Reynolds B.A., and Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255 (1992) 1707-1710
11. Conti L., Pollard S.M., Gorba T., Reitano E., Toselli M., Biella G., Sun Y., Sanzone S., Ying Q.L., Cattaneo E., and Smith A. Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol. 3 (2005) e283
12. Stavridis M.P., and Smith A.G. Neural differentiation of mouse embryonic stem cells. Biochem. Soc. Trans. 31 (2003) 45-49
13. Zong Y., Zhou S., Fatima S., and Sorrentino B.P. Expression of mouse Abcg2 mRNA during hematopoiesis is regulated by alternative use of multiple leader exons and promoters. J. Biol. Chem. 281 (2006) 29625-29632
14. E. Himeno, S. Tanaka, T. Kunath, Isolation and manipulation of mouse trophoblast stem cells, Curr. Protoc. Stem Cell Biol. (2008) Unit 1E 4 (Chapter 1).
15. Maliepaard M., Scheffer G.L., Faneyte I.F., van Gastelen M.A., Pijnenborg A.C., Schinkel A.H., van De Vijver M.J., Scheper R.J., and Schellens J.H. Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Res. 61 (2001) 3458-3464
16. Tadjali M., Zhou S., Rehg J., and Sorrentino B.P. Prospective isolation of murine hematopoietic stem cells by expression of an Abcg2/GFP allele. Stem Cells 24 (2006) 1556-1563
17. Bhattacharya S., Das A., Mallya K., and Ahmad I. Maintenance of retinal stem cells by Abcg2 is regulated by notch signaling. J. Cell Sci. 120 (2007) 2652-2662
18. Mizrak D., Brittan M., and Alison M.R. CD133: molecule of the moment. J. Pathol. 214 (2008) 3-9
19. Corti S., Nizzardo M., Nardini M., Donadoni C., Locatelli F., Papadimitriou D., Salani S., Del Bo R., Ghezzi S., Strazzer S., Bresolin N., and Comi G.P. Isolation and characterization of murine neural stem/progenitor cells based on Prominin-1 expression. Exp. Neurol. 205 (2007) 547-562
20. Segal M.B. The choroid plexuses and the barriers between the blood and the cerebrospinal fluid. Cell Mol. Neurobiol. 20 (2000) 183-196
21. Imayoshi I., Shimogori T., Ohtsuka T., and Kageyama R. Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development 135 (2008) 2531-2541
22. Lin G., Finger E., and Gutierrez-Ramos J.C. Expression of CD34 in endothelial cells, hematopoietic progenitors and nervous cells in fetal and adult mouse tissues. Eur. J. Immunol. 25 (1995) 1508-1516
23. Ogawa Y., Takebayashi H., Takahashi M., Osumi N., Iwasaki Y., and Ikenaka K. Gliogenic radial glial cells show heterogeneity in the developing mouse spinal cord. Dev. Neurosci. 27 (2005) 364-377
24. Glaser T., Pollard S.M., Smith A., and Brustle O. Tripotential differentiation of adherently expandable neural stem (NS) cells. PLoS ONE 2 (2007) e298
25. Basak O., and Taylor V. Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression. Eur. J. Neurosci. 25 (2007) 1006-1022
26. Kim M., and Morshead C.M. Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis. J. Neurosci. 23 (2003) 10703-10709
27. Gabay L., Lowell S., Rubin L.L., and Anderson D.J. Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron 40 (2003) 485-499
28. Dromard C., Bartolami S., Deleyrolle L., Takebayashi H., Ripoll C., Simonneau L., Prome S., Puech S., Tran V.B., Duperray C., Valmier J., Privat A., and Hugnot J.P. NG2 and Olig2 expression provides evidence for phenotypic deregulation of cultured central nervous system and peripheral nervous system neural precursor cells. Stem Cells 25 (2007) 340-353
29. Shen Q., Wang Y., Kokovay E., Lin G., Chuang S.M., Goderie S.K., Roysam B., and Temple S. Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. Cell Stem Cell 3 (2008) 289-300
30. Roberts L.M., Black D.S., Raman C., Woodford K., Zhou M., Haggerty J.E., Yan A.T., Cwirla S.E., and Grindstaff K.K. Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation. Neuroscience 155 (2008) 423-438
31. Ozvegy-Laczka C., Laczko R., Hegedus C., Litman T., Varady G., Goda K., Hegedus T., Dokholyan N.V., Sorrentino B.P., Varadi A., and Sarkadi B. Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter. J. Biol. Chem. 283 (2008) 26059-26070