Local anaesthetic use for the iliac crest-donor site: Pharmacokinetic and pharmacodynamic evaluations

Acta Anaesthesiologica Belgica

Volumn 60, Issue 1, 2009, Pages 39-45

  Estebe, Jean Pierre ^a,b   Le Corre, P ^b   Le Naoures, A ^a,b   Eliat, C ^a,b   Chevanne, F ^b   Husson, J L ^b   Ecoffey, C ^a  

^a centre hospitalier régional de Troyes   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Analgesia; Bone graft harvest; Bupivacaine; Bupivacaine loaded microspheres; Iliac crest; Local anaesthetics; Post operative pain; Ropivacaine; Wound infiltration

Indexed keywords

BUPIVACAINE; MORPHINE; ROPIVACAINE;

ABSENCE OF SIDE EFFECTS; ANESTHESIA INDUCTION; ANESTHESIA MECHANISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE PAIN; BONE TRANSPLANTATION; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DONOR SITE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DOSE TITRATION; DRUG MEGADOSE; HUMAN; ILIAC CREST; LOCAL ANESTHESIA; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PERIOD; SHEEP; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; VISUAL ANALOG SCALE;

AMIDES; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; ANESTHESIA, LOCAL; ANESTHETICS, LOCAL; ANIMALS; BONE TRANSPLANTATION; BUPIVACAINE; DELAYED-ACTION PREPARATIONS; DOUBLE-BLIND METHOD; DRUG DELIVERY SYSTEMS; EXTREMITIES; FEMALE; HUMANS; ILIUM; MALE; MICROSPHERES; MORPHINE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PROSPECTIVE STUDIES; SHEEP; SODIUM CHLORIDE;

EID: 65649135523     PISSN: 00015164     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Goulet J. A., Senunas L. E., DeSilva G. L., Greenfield M. L., Autogenous iliac crest bone graft. Complications and functional assessment, CLIN. ORTHOP., 339, 76-81, 1997.
2. Todd B. D., Reed S. C., The use of bupivacaine to relieve pain at iliac graft donor sites, INT. ORTHOP., 15, 53-5, 1991.
3. Heary R. F., Schleuk R. P., Sacchieri T. A., Barone D., Brotea C., Persistent iliac crest donor site pain: Independent outcome assessment, NEUROSURGERY, 50, 510-6, 2002.
4. Blumenthal S., Dullenkopf A., Rentsch K., Borgeat A., Continuous ropivacaine infusion at the iliac crest donor site is an effective technique for postoperative analgesia, ANESTHESIOLOGY, 102, 392-7, 2005.
5. Le Guevello P., Le Corre P., Chevanne F., Le Verge R., High-performance liquid chromatographic determination of bupivacaine in plasma samples for biopharmaceutical studies and application to seven other local anaesthetics, J. CHROMATOGR., 622, 284-90, 1993.
6. Estebe J. P., Lecacheur S., Le Naoures A., Leroy M., Ecoffey C., Wound infiltration of iliac bone craft harvest site with ropivacaine, ANESTHESIOLOGY, 93, A878, 2000.
7. Dunstan S. P., Korczak P. K., Use of epidural catheter for postoperative pain relief for bone harvesting from iliac crest, BR. J. ORAL. MAXILLOFAC. SURG., 34, 436-7, 1996.
8. Estebe J. P., Le Corre P., Du Plessis L., et al., The pharmacokinetics and pharmacodynamics of bupivacaine-loaded microspheres on brachial plexus block in a sheep, ANESTH. ANALG., 93, 447-55, 2001.
9. Heckman J. D., Ehler W., Brooks B. P., et al., Bone morphogenetic protein but not transforming growth factor-b enhances bone formation in canine diaphysial nonunions implanted with a biodegradable composite polymer, J. BONE JOINT. SURG. AM., 81, 1717-29, 1999.
10. Le Corre P., Estebe J. P., Clement R., et al., Spray-dryed bupivacaine-loaded microspheres: In vitro evaluation, and biopharmaceutics of bupivacaine following brachial plexus administration in sheep, INT. J. PHARM., 238, 191-203, 2002.
11. Hoard M. A., Bill T. J., Campbell R. L., Reduction in morbidity after iliac crest bone harvesting: The concept of preemptive analgesia, J. CRANIOFAC. SURG., 9, 448-51, 1998.
12. Cowan N., Young J., Murphy D., Bladen C., Double-blind, randomized, controlled trial of local anesthetic use for iliac crest donor site pain, J. NEUROSCI. NURS., 34, 205-10, 2002.
13. Ahlmann E., Patzakis M., Roidis N., Shepherd L., Holtom P., Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes, J. BONE JOINT. SURG. AM., 84, 716-20, 2002.
14. Guinet P., Estebe J. P., Ratajczk M., Banssard J. Y., Chevanne F., Beck D., Le Corre P., Wodey E., Ecoffey C., Electrocardiographic and hemodynamic effects of intravenous infusion of bupivacaine, ropivacaine, levobupivacaine, and lidocaine in anesthetized sheep, REG. ANESTH. PAIN MED., 34, 17-23, 2009.
15. Gundes H., Kilickan L., Gurkan Y, Sarlak A., Toker K., Short- and long-term effects of regional application of morphine and bupivacaine on the iliac crest donor, ACTA ORTHOP. BELG., 66, 341-4, 2000.
16. Reuben S. S., Vieira P., Faruqi S., Verghis A., Kilaru P. A., Maciolek H., Local administration of morphine for analgesia after iliac bone graft harvest, ANESTHESIOLOGY, 95, 390-4, 2001.
17. Puri R., Moskovich R., Gusmorino P., Shott S., Bupivacaine for postoperative pain relief at the iliac crest bone graft harvest site, AM. J. ORTHOP., 29, 443-6, 2000.
18. Estebe J. P., Le Corre P., Chevanne F., Cathelineau G., Le Verge R., Ecoffey C., Motor blockade by brachial plexus block in the sheep, ANESTHESIOLOGY, 93, 291-3, 2000.
19. Ratajczak-Enselme M., Estebe J. P., Wodey E., Malinovsky J. M., Chevanne F., Dollo G., Ecoffey C., Le Corre P., Epidural, intrathecal and plasma pharmacokinetic study of epidural ropivacaine-loaded-PLGA microspheres in a sheep model, EUR. J. PHARM. BIOPHARM., 72, 54-61, 2009.