Design of experiment (DoE) as a tool for the optimization of source conditions in SEC-ESI-MS of functional synthetic polymers synthesized via ATRP

Macromolecular Rapid Communications

Volumn 30, Issue 8, 2009, Pages 589-597

  Gruendling, Till ^a,b   Guilhaus, Michael ^b   Barner Kowollik, Christopher ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Design of experiment (DoE); ESI source optimization; Ionization efficiency; Poly(methyl methacrylate); Radical polymerization; Response surface design; Reversible addition fragmentation chain transfer (RAFT); Size exclusion chromatography electrospray ionization mass spectrometry (SEC ESI MS)

Indexed keywords

DESIGN OF EXPERIMENT (DOE); ESI SOURCE OPTIMIZATION; IONIZATION EFFICIENCY; RADICAL POLYMERIZATION; RESPONSE SURFACE DESIGN; REVERSIBLE ADDITION FRAGMENTATION CHAIN TRANSFER (RAFT);

ACRYLIC MONOMERS; ATOM TRANSFER RADICAL POLYMERIZATION; CHROMATOGRAPHIC ANALYSIS; DESIGN OF EXPERIMENTS; ESTERS; FREE RADICAL POLYMERIZATION; FUNCTIONAL POLYMERS; GEL PERMEATION CHROMATOGRAPHY; ION SOURCES; IONIZATION; MASS SPECTROMETERS; MASS SPECTROMETRY; OPTIMIZATION; POLYMERS; SIZE EXCLUSION CHROMATOGRAPHY; SPECTRUM ANALYSIS; STATISTICS; SURFACE PROPERTIES;

ELECTROSPRAY IONIZATION;

EID: 65649134698     PISSN: 10221336     EISSN: 15213927     Source Type: Journal    
DOI: 10.1002/marc.200800738     Document Type: Article

References (38)

1. L. Barner, T. P. Davis, M. H. Stenzel, C. Barner-Kowollik, Macromol. Rapid Commun. 2007, 28, 539.
2. M. H. Stenzel, Chem. Commun. 2008, 30, 3486.
3. S. Yang, Q. Li, L. Chen, S. Chen, J. Mater. Chem. 2008, 18, 5599.
4. quot;Handbook of RAFT Polymerization", C. Barner-Kowollik, Ed., Wiley-VCH, Weinheim 2008.
5. S. Perrier, P. Takolpuckdee, J. Polym. Sci. A: Polym. Chem. 2006, 43, 5347.
6. K. Matyjaszewski, J. Xia, Chem. Rev. 2001, 101, 2921.
7. C. J. Hawker, A. W. Bosman, E. Harth, Chem. Rev. 2001, 301, 3661.
8. C. Barner-Kowollik, T. P. Davis, M. H. Stenzel, Polymer 2004, 45, 7791.
9. G. Hart-Smith, T. Lovestead, T. P. Davis, M. H. Stenzel, C. Barner-Kowollik, Biomacromolecules 2007, 8, 2404;
10. G. Hart-Smith, H. Chaffey-Millar, C. Barner-Kowollik, Macro-molecules 2008, 41, 3023;
11. M. Buback, H. Frauendorf, F. Günzler, P. Vana, J. Polym. Sci., Polym. Chem. 2007, 45, 2453;
12. M. Buback, H. Frauendorf, F. Günzler, P. Vana, Polymer 2007, 48, 5590;
13. Z. Szablan, T. Junkers, S. P. S. Koo, T. Lovestead, T. P. Davis, M. H. Stenzel, C. Barner-Kowollik, Macromolecules 2007, 40, 6820.
14. J. H. Scrivens, A. T. Jackson, Int. J. Mass Spectrom. 2000, 200, 261.
15. K. Tanaka, Angew. Chem., Int. Ed. 2003, 42, 3861.
16. P. M. Peacock, C. N. McEwen, Anal. Chem. 2006, 78, 3957.
17. S. M. Weidner, S. Trimpin, Anal. Chem. 2008, 80, 4349.
18. M. J. Polce, M. Ocampo, R. P. Quirk, C. Wesdemiotis, Anal. Chem. 2008, 80, 347.
19. T. Gruendling, G. Hart-Smith, T. P. Davis, M. H. Stenzel, C. Barner-Kowollik, Macromolecules 2008, 41, 1966.
20. A. T. Jackson, A. Bunn, I. M. Priestnall, C. D. Borman, D. J. Irvine, Polymer 2006, 47, 1044.
21. X. Jiang, P. J. Schoenmakers, J. L. J. van Dongen, X. Lou, V. Lima, J. Brokken-Zijp, Anal. Chem. 2003, 75, 5517.
22. R. Murgasova, D. M. Hercules, Anal. Bioanal. Chem. 2002, 373, 481.
23. T. Gruendling, M. Guilhaus, C. Barner-Kowollik, Anal. Chem. 2008, 80, 6915.
24. D. J. Aaserud, L. Prokai, W. J. J. Simonsick, Anal. Chem. 1999, 71, 4793.
25. W. Naidong, Y.-L. Chen, W. Shou, X. Jiang, J. Pharm. Biomed. Anal. 2001, 26, 753.
26. nd edition, P. Gemperline, Ed., CRC Press, Boca Raton 2006.
27. A. Asperger, J. Efer, T. Koal, W. Engewald, J. Chromatogr. A 2001, 937, 65.
28. M. Sautour, A. Rouget, P. Dentigny, C. Divies, M. Bensoussan, J. Appl. Microbiol. 2001, 91, 900.
29. V. Tak, P. K. Kanaujia, D. Pardasani, R. Kumar, R. K. Srivastava, A. K. Gupta, D. K. Dubey, J. Chromatogr. A 2007, 1161, 198.
30. S. Rudaz, S. Cherkaoui, J.-Y. Gauvrit, P. Lantéri, J.-L. Veuthey, Electrophoresis 2001, 22, 3316.
31. K. Bateman, C. Seto, B. Gunter, J. Am. Soc. Mass Spectrom. 2002, 13, 2.
32. L. S. Riter, O. Vitek, K. M. Gooding, B. D. Hodge, R. K. J. Julian, J. Mass Spectrom. 2005, 40, 565.
33. M. A. R. Meier, N. Adams, U. S. Schubert, Anal. Chem. 2007, 79, 863.
34. S. M. Hunt, M. M. Sheil, M. Belov, P. J. Derrick, Anal. Chem. 1998, 70, 1812.
35. R. B. Cole, J. Mass Spectrom. 2000, 35, 763.
36. C. D. Borman, A. T. Jackson, A. Bunn, A. L. Cutter, D. J. Irvine, Polymer 2000, 41, 6015.
37. A. T. Iavarone, E. R. Williams, Int. J. Mass Spectrom. 2002, 219, 63.
38. M. Bednarek, T. Biedron, P. Kubisa, Macromol. Chem. Phys. 2000, 201, 58.