High-expression of sphingomyelin deacylase is an important determinant of ceramide deficiency leading to barrier disruption in atopic dermatitis

Journal of Investigative Dermatology

Volumn 115, Issue 3, 2000, Pages 406-413

  Hara, Junko ^a   Higuchi, Kazuhiko ^a   Okamoto, Reiko ^a   Kawashima, Makoto ^a   Imokawa, Genji ^b  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b KAO CORPORATION   (Japan)

Author keywords

Atopic dermatitis; Ceramide; Sphingomyelin; Sphingomyelin deacylase; Sphingomyelinase

Indexed keywords

CERAMIDE; FATTY ACID; GLUCOSYLCERAMIDE; PALMITIC ACID; PHOSPHORYLCHOLINE; SPHINGOMYELIN; SPHINGOMYELIN DEACYLASE; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROLYSIS; LIPID METABOLISM; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRATUM CORNEUM;

EID: 0033828399     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00072.x     Document Type: Article

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