Patterns of cardiac perfusion abnormalities after chemoradiotherapy in patients with lung cancer

Journal of Thoracic Oncology

Volumn 4, Issue 2, 2009, Pages 179-184

  Gayed, Isis W ^a,f   Liu, H Helen ^b   Wei, Xiong ^b   Liao, Zhongxing ^c   Yusuf, Syed Wamique ^d   Chang, Joe Y ^c   Bassett, Roland ^e   Komaki, Ritsuko ^c  

^a Nuclear Medicine Department S 216   (United States)

^b Departments of Radiation Physics

^c Departments of Radiation Oncology

^d Departments of Departments of Cardiology

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^f UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Chemoradiation; Lung cancer; Myocardial perfusion imaging; Radiation therapy

Indexed keywords

AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CANCER RECURRENCE; CANCER STAGING; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DYSLIPIDEMIA; FEMALE; HEART DISEASE; HEART MUSCLE PERFUSION; HEART MUSCLE PERFUSION ABNORMALITY; HUMAN; HYPERTENSION; INTENSITY MODULATED RADIATION THERAPY; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MALE; OBESITY; PRIORITY JOURNAL; RADIATION DOSE; SMOKING; COMPUTER ASSISTED TOMOGRAPHY; CORONARY ARTERY BLOOD FLOW; HEART MUSCLE ISCHEMIA; HEART SCINTISCANNING; HEART SEPTUM DEFECT; LUNG TUMOR; MULTIMODALITY CANCER THERAPY; PROGNOSIS; PROSPECTIVE STUDY; RADIATION EXPOSURE; RADIATION INJURY; RADIOGRAPHY; RISK FACTOR; TREATMENT OUTCOME;

AGED; CARCINOMA, NON-SMALL-CELL LUNG; COMBINED MODALITY THERAPY; CORONARY CIRCULATION; FEMALE; HEART SEPTAL DEFECTS; HUMANS; LUNG NEOPLASMS; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIAL PERFUSION IMAGING; PROGNOSIS; PROSPECTIVE STUDIES; RADIATION INJURIES; RADIOTHERAPY, INTENSITY-MODULATED; RISK FACTORS; SMALL CELL LUNG CARCINOMA; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 65649124591     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3181990c46     Document Type: Article

References (27)

1. Early Breast Cancer Trialists' Collaborative Group. Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the randomized trials. Lancet 2000;355: 1757-1770.
2. Adams MJ, Lipsitz SR, Colan SD, et al. Cardiovascular status in long-term survivors of Hodgkin's disease treated with chest radiotherapy. J Clin Oncol 2004;22: 3139-3148.
3. Cuzick J, Stewart H, Rutquivst L, et al. Cause-specific mortality in long-term survivors of breast cancer who participated in trials of radiotherapy. J Clin Oncol 1994;12: 447-452.
4. Rutquivst LE, Lax I, Fornando T, et al. Cardiovascular mortality in a randomized trial of adjuvant radiation therapy versus surgery alone in primary breast cancer. Int Radiat Oncol Biol Phys 1992;22: 887-896.
5. Biovin JF, Hutchinson GB, Lubin JH, et al. Coronary artery disease mortality in patients treated for Hodgkin's disease. Cancer 1992;69: 1241-1247.
6. Hancock SL, Tucker MA, Hoppe RT. Factors affecting late mortality from heart disease after treatment of Hodgkin's disease. JAMA 1993; 270: 1949-1955.
7. Galderisi M, Marra F, Esposito R, et al. Cancer therapy and cardiotoxicity: the need of serial Doppler echocardiography. Cardiovasc Ultrasound 2007;5: 4.
8. Heidenreich PA, Schnittger I, William Straus H, et al. Screening for coronary artery disease after mediastinal irradiation for Hodgkin's disease. J Clin Oncol 2007;25: 43- 49. Erratum in: J Clin Oncol 2007;25: 1635.
9. Hong EC, Kimura-Hayama ET, Di Carli MF. Hybrid cardiac imaging: complementary roles of CT angiography and PET in a patient with a history of radiation therapy. J Nucl Cardiol 2007;14: 617-620.
10. Goethals I, De Winter O, De Bondt P, et al. The clinical value of nuclear medicine in the assessment of irradiation-induced and anthracyclineassociated cardiac damage. Ann Oncol 2002;13: 1331-1339.
11. Gyenes G, Fornander T, Carlens P, et al. Detection of radiation induced myocardial damage by technetium-99m sestamibi scintigraphy. Eur J Nucl Med 1997;24: 286-292.
12. Gyenes G, Fornander T, Carlens P, et al. Myocardial damage in breast cancer patients treated with adjuvant radiotherapy: a prospective study. Int J Radiat Oncol Biol Phys 1996;36: 899-905.
13. Handenbergh PH, Munely MT, Bentel GC, et al. Cardiac perfusion changes in patients treated for breast cancer with radiation therapy and doxorubicin: preliminary results. Int J Radiat Oncol Biol Phys 2001;49: 1023-1028.
14. Lind PA, Pahnanelli R, Marks LB, et al. Myocardial perfusion changes in patients irradiated for left-sided breast cancer and correlation with coronary artery distribution. Int J Radiat Oncol Biol Phys 2003;55: 914-992
15. Marks LB, Yu X, Prosnitz RG, et al. The incidence and functional consequences of RT-associated cardiac perfusion defects. Int J Radiat Oncol Biol Phys 2005;63: 214-223.
16. Perrault DJ, Levy M, Herman JD, et al. Echocardiographic abnormalities following cardiac radiation. J Clin Oncol 1985;3: 546-551.
17. Gustavsson A, Eskilsson J, Landberg T, et al. Late cardiac effects after mantle radiotherapy in patients with Hodgkin's disease. Ann Oncol 1990;1: 355-363.
18. Espey DK, Wu X, Swan J, Wiggins C, et al. Annual Report to the Nation on the Status of Cancer, 1975-2004, Featuring Cancer in American Indians and Alaska Natives. Cancer 2007;110: 2119-2152.
19. Gayed IW, Liu HH, Yusuf SW, et al. The prevalence of myocardial ischemia after concurrent chemoradiation therapy as detected by gated myocardial perfusion imaging in patients with esophageal cancer. J Nucl Med 2006;47: 1756-1762.
20. Yu X, Prosnitz R, Zhou S, et al. Symptomatic cardiac events following radiation therapy for left-sided breast cancer: possible association with radiation therapy-induced changes in regional perfusion. Clin Breast Cancer 2003;4: 193-197.
21. Harris EER, Correa C, Hwang WT, et al. Late cardiac Mortality and morbidity in early-stage beast cancer patients after breast-conservation treatment. J Clin Oncol 2006;24: 4100-4106.
22. Brosius FC, Waller BF, Roberts WC. Radiation induced analysis of the 16 young (aged 15-33 years) necropsy patients who received over 3500 rads to the heart. Am J Med 1981;70: 519-530.
23. Girinsky T, Pichento C, Beaudre A, et al. Is intensity-modulated radiotherapy better than conventional radiation treatment and three-dimensional conformal radiotherapy for mediastinal masses in patients with Hodgkin's disease, and is there a role for beam orientation optimization and dose constraints assigned to virtual volumes? Int J Radiat Oncol Biol Phys 2006;64: 218-226.
24. Veinot JP, Edwards WD. Pathology of radiation-induced heart disease: a surgical and autopsy study of 27 cases. Hum Pathol 1996;27: 766-773.
25. Letsas KP, Korantzopoulos P, Evanelou D, et al. Acute myocardial infarction with normal coronary arteries in a patient with Hodgkin's disease: a late complication of irradiation and chemotherapy. Tex Heart Inst J 2006;33: 512-514.
26. Higgins JA, Higgins JP, Williams G. Stress-induced abnormalities in myocardial perfusion imaging that are not related to perfusion but are of diagnostic and prognostic importance. Eur J Nucl Med Mol Imaging 2007;34: 584-595.
27. Budoff MJ, Rasouli ML, Shavelle DM, et al. Cardiac CT angiography (CTA) and nuclear myocardial perfusion imaging (MPI)-A comparison in detecting significant coronary artery disease. Acad Radiol 2007;14: 252-257.