-
1
-
-
33846385587
-
Mammalian cytochromes P450 - importance of tissue specificity
-
Seliskar M, Rozman D: Mammalian cytochromes P450 - importance of tissue specificity. Biochim. Biophys. Acta 1770, 458-466 (2007).
-
(2007)
Biochim. Biophys. Acta
, vol.1770
, pp. 458-466
-
-
Seliskar, M.1
Rozman, D.2
-
2
-
-
6344250770
-
57 varieties: The human cytochromes P450
-
Lewis DF: 57 varieties: the human cytochromes P450. Pharmacogenomics 5, 305-318 (2004).
-
(2004)
Pharmacogenomics
, vol.5
, pp. 305-318
-
-
Lewis, D.F.1
-
3
-
-
38949094492
-
Cytochrome p450 and chemical toxicology
-
Guengerich FP: Cytochrome p450 and chemical toxicology. Chem. Res. Toxicol. 21, 70-83 (2008).
-
(2008)
Chem. Res. Toxicol
, vol.21
, pp. 70-83
-
-
Guengerich, F.P.1
-
4
-
-
27644596457
-
Predicting in vivo drug interactions from in vitro drug discovery data
-
Wienkers LC, Heath TG: Predicting in vivo drug interactions from in vitro drug discovery data. Nat. Rev. Drug Discov. 4, 825-833 (2005).
-
(2005)
Nat. Rev. Drug Discov
, vol.4
, pp. 825-833
-
-
Wienkers, L.C.1
Heath, T.G.2
-
5
-
-
0031748173
-
In vitro and in vivo drug interactions involving human CYP3A
-
Thummel KE, Wilkinson GR: In vitro and in vivo drug interactions involving human CYP3A. Annu. Rev. Pharmacol. Toxicol. 38, 389-430 (1998).
-
(1998)
Annu. Rev. Pharmacol. Toxicol
, vol.38
, pp. 389-430
-
-
Thummel, K.E.1
Wilkinson, G.R.2
-
6
-
-
33748787999
-
Pharmacogenetics, drug-metabolizing enzymes, and clinical practice
-
Gardiner SJ, Begg EJ: Pharmacogenetics, drug-metabolizing enzymes, and clinical practice. Pharmacol. Rev. 58, 521-590 (2006).
-
(2006)
Pharmacol. Rev
, vol.58
, pp. 521-590
-
-
Gardiner, S.J.1
Begg, E.J.2
-
7
-
-
0034638766
-
Pharmacogenetics and adverse drug reactions
-
Meyer UA: Pharmacogenetics and adverse drug reactions. Lancet 356, 1667-1671 (2000).
-
(2000)
Lancet
, vol.356
, pp. 1667-1671
-
-
Meyer, U.A.1
-
8
-
-
42549147841
-
Prospective study of warfarin dosage requirements based on CYP2C9 and VKORC1 genotypes
-
Wen MS, Lee M, Chen JJ et al.: Prospective study of warfarin dosage requirements based on CYP2C9 and VKORC1 genotypes. Clin. Pharmacol. Ther. 84, 83-89 (2008).
-
(2008)
Clin. Pharmacol. Ther
, vol.84
, pp. 83-89
-
-
Wen, M.S.1
Lee, M.2
Chen, J.J.3
-
9
-
-
6344285930
-
Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population
-
Solus JF, Arietta BJ, Harris JR et al.: Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population. Pharmacogenomics 5, 895-931 (2004).
-
(2004)
Pharmacogenomics
, vol.5
, pp. 895-931
-
-
Solus, J.F.1
Arietta, B.J.2
Harris, J.R.3
-
10
-
-
0036124107
-
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
-
Bradford LD: CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 3, 229-243 (2002).
-
(2002)
Pharmacogenomics
, vol.3
, pp. 229-243
-
-
Bradford, L.D.1
-
11
-
-
33847031732
-
CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure
-
Sistonen J, Sajantila A, Lao O, Corander J, Barbujani G, Fuselli S: CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure. Pharmacogenet. Genomics 17, 93-101 (2007).
-
(2007)
Pharmacogenet. Genomics
, vol.17
, pp. 93-101
-
-
Sistonen, J.1
Sajantila, A.2
Lao, O.3
Corander, J.4
Barbujani, G.5
Fuselli, S.6
-
12
-
-
48949119312
-
Genetic polymofphism analysis of CYP2C19 in Chinese Han populations from different geographic areas of mainland China
-
Chen L, Qin S, Xie J et al.: Genetic polymofphism analysis of CYP2C19 in Chinese Han populations from different geographic areas of mainland China. Pharmacogenomics 9, 691-702 (2008).
-
(2008)
Pharmacogenomics
, vol.9
, pp. 691-702
-
-
Chen, L.1
Qin, S.2
Xie, J.3
-
13
-
-
0034816629
-
Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: Impairment of its promoter activity
-
Pitarque M, von Richter O, Oke B, Berkkan H, Oscarson M, Ingelman-Sundberg M: Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: impairment of its promoter activity. Biochem. Biophys. Res. Commun. 284, 455-460 (2001).
-
(2001)
Biochem. Biophys. Res. Commun
, vol.284
, pp. 455-460
-
-
Pitarque, M.1
von Richter, O.2
Oke, B.3
Berkkan, H.4
Oscarson, M.5
Ingelman-Sundberg, M.6
-
14
-
-
0036389893
-
Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity
-
Oscarson M, McLellan RA, Asp V et al.: Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity. Hum. Mutat. 20, 275-283 (2002).
-
(2002)
Hum. Mutat
, vol.20
, pp. 275-283
-
-
Oscarson, M.1
McLellan, R.A.2
Asp, V.3
-
15
-
-
0033608176
-
Validation of methods for CYP2C9 genotyping: Frequencies of mutant alleles in a Swedish population
-
Yasar U, Eliasson E, Dahl ML, Johansson I, Ingelman-Sundberg M, Sjoqvist F: Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population. Biochem. Biophys. Res. Commun. 254, 628-631 (1999).
-
(1999)
Biochem. Biophys. Res. Commun
, vol.254
, pp. 628-631
-
-
Yasar, U.1
Eliasson, E.2
Dahl, M.L.3
Johansson, I.4
Ingelman-Sundberg, M.5
Sjoqvist, F.6
-
16
-
-
0038434387
-
Frequency of cytochrome P450 2C9 allelic variants in the Chinese and French populations
-
Yang JQ, Morin S, Vefstuyft C et al.: Frequency of cytochrome P450 2C9 allelic variants in the Chinese and French populations. Fundam. Clin. Pharmacol. 17, 373-376 (2003).
-
(2003)
Fundam. Clin. Pharmacol
, vol.17
, pp. 373-376
-
-
Yang, J.Q.1
Morin, S.2
Vefstuyft, C.3
-
17
-
-
24944503322
-
A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity
-
Yuan HY, Chen JJ, Lee MT et al.: A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity. Hum. Mol. Genet. 14, 1745-1751 (2005).
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 1745-1751
-
-
Yuan, H.Y.1
Chen, J.J.2
Lee, M.T.3
-
18
-
-
33749052540
-
The high prevalence of the poor and ultrarapid metabolite alleles of CYP2D6, CYP2C9, CYP2C19, CYP3A4, and CYP3A5 in Taiwanese population
-
Liou YH, Lin CT, Wu YJ, Wu LS: The high prevalence of the poor and ultrarapid metabolite alleles of CYP2D6, CYP2C9, CYP2C19, CYP3A4, and CYP3A5 in Taiwanese population. J. Hum. Genet. 51, 857-863 (2006).
-
(2006)
J. Hum. Genet
, vol.51
, pp. 857-863
-
-
Liou, Y.H.1
Lin, C.T.2
Wu, Y.J.3
Wu, L.S.4
-
19
-
-
34047117007
-
The association of CYP2C9 gene polymorphisms with colorectal carcinoma in Han Chinese
-
Liao LH, Zhang H, Lai MP et al.: The association of CYP2C9 gene polymorphisms with colorectal carcinoma in Han Chinese. Clin. Chim. Acta 380, 191-196 (2007).
-
(2007)
Clin. Chim. Acta
, vol.380
, pp. 191-196
-
-
Liao, L.H.1
Zhang, H.2
Lai, M.P.3
-
20
-
-
33646753192
-
Han Chinese cell and genome bank in Taiwan: Purpose, design and ethical considerations
-
Pan WH, Fann CS, Wu JY et al.: Han Chinese cell and genome bank in Taiwan: purpose, design and ethical considerations. Hum. Hered. 61, 27-30 (2006).
-
(2006)
Hum. Hered
, vol.61
, pp. 27-30
-
-
Pan, W.H.1
Fann, C.S.2
Wu, J.Y.3
-
21
-
-
0033590590
-
Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes
-
Lundqvist E, Johansson I. Ingelman-Sundberg M: Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes. Gene 226, 327-338 (1999).
-
(1999)
Gene
, vol.226
, pp. 327-338
-
-
Lundqvist, E.1
Johansson, I.2
Ingelman-Sundberg, M.3
-
22
-
-
33644694277
-
Novel structure of the CYP2D6 gene that confuses genotyping for the CYP2D6*5 allele
-
Fukuda T, Maune H, Ikenaga Y, Naohara M, Fukuda K, Azuma J: Novel structure of the CYP2D6 gene that confuses genotyping for the CYP2D6*5 allele. Drug Metab. Pharmacokinet. 20, 345-350 (2005).
-
(2005)
Drug Metab. Pharmacokinet
, vol.20
, pp. 345-350
-
-
Fukuda, T.1
Maune, H.2
Ikenaga, Y.3
Naohara, M.4
Fukuda, K.5
Azuma, J.6
-
23
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW et al. The sequence of the human genome. Science 291, 1304-1351 (2001).
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
-
24
-
-
0032963135
-
G169R mutation diminishes the metabolic activity of CYP2136 in Chinese
-
Wang SL, Lai MD, Huang JD: G169R mutation diminishes the metabolic activity of CYP2136 in Chinese. Drug Metab. Dispos. 27, 385-388 (1999).
-
(1999)
Drug Metab. Dispos
, vol.27
, pp. 385-388
-
-
Wang, S.L.1
Lai, M.D.2
Huang, J.D.3
-
25
-
-
0036089729
-
Single-step assays to analyze CYP2D6 gene polymorphisms in Asians: Allele, frequencies and a novel *14B allele in mainland Chinese
-
Ji L, Pan S, Marti-Jaun J, Hanseler E, Rentsch K, Hersberger M: Single-step assays to analyze CYP2D6 gene polymorphisms in Asians: allele, frequencies and a novel *14B allele in mainland Chinese. Clin. Chem. 48, 983-988 (2002).
-
(2002)
Clin. Chem
, vol.48
, pp. 983-988
-
-
Ji, L.1
Pan, S.2
Marti-Jaun, J.3
Hanseler, E.4
Rentsch, K.5
Hersberger, M.6
-
26
-
-
0028806579
-
A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency
-
Broly F, Marez D, Lo Guidice JM et al.: A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency. Hum. Genet. 96, 601-603 (1995).
-
(1995)
Hum. Genet
, vol.96
, pp. 601-603
-
-
Broly, F.1
Marez, D.2
Lo Guidice, J.M.3
-
27
-
-
0033965373
-
Genetic analysis of the CYP2D6 locus in a Hong Kong Chinese population
-
Garcia-Barcelo M, Chow Ly, Chiu HF et al. Genetic analysis of the CYP2D6 locus in a Hong Kong Chinese population. Clin. Chem. 46, 18-23 (2000).
-
(2000)
Clin. Chem
, vol.46
, pp. 18-23
-
-
Garcia-Barcelo, M.1
Ly, C.2
Chiu, H.F.3
-
28
-
-
0028182215
-
Frequency of human CYP2D6 mutant alleles in a normal Chinese population
-
Lee EJ, Jeyaseelan K: Frequency of human CYP2D6 mutant alleles in a normal Chinese population. Br. J. Clin. Pharmarol. 37, 605-607 (1994).
-
(1994)
Br. J. Clin. Pharmarol
, vol.37
, pp. 605-607
-
-
Lee, E.J.1
Jeyaseelan, K.2
-
29
-
-
0027418152
-
Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: Polymorphism in RFLP and DNA sequence of CYP2D6
-
Wang SL, Huang JD, Mai MD, Liu BH, Lai ML: Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6. Clin. Pharmacol. Ther. 53, 410-418 (1993).
-
(1993)
Clin. Pharmacol. Ther
, vol.53
, pp. 410-418
-
-
Wang, S.L.1
Huang, J.D.2
Mai, M.D.3
Liu, B.H.4
Lai, M.L.5
-
30
-
-
0037757965
-
Effects of polymorphism in promoter region of human CYP2A6 gene (CYP2A6*9) on expression level of messenger ribonucleic acid and enzymatic activity in vivo and in vitro
-
Yoshida R, Nakajima M, Nishimura K, Tokudome S, Kwon JT, Yokoi T: Effects of polymorphism in promoter region of human CYP2A6 gene (CYP2A6*9) on expression level of messenger ribonucleic acid and enzymatic activity in vivo and in vitro. Clin. Pharmacol. Ther. 74, 69-76 (2003).
-
(2003)
Clin. Pharmacol. Ther
, vol.74
, pp. 69-76
-
-
Yoshida, R.1
Nakajima, M.2
Nishimura, K.3
Tokudome, S.4
Kwon, J.T.5
Yokoi, T.6
-
31
-
-
0037378823
-
Functional characterization of cytochrome P450 2B6 allelic variants
-
Jinno H, Tanaka-Kagawa, T, Ohno A et al.: Functional characterization of cytochrome P450 2B6 allelic variants. Drug Metab. Dispos. 31, 398-403 (2003).
-
(2003)
Drug Metab. Dispos
, vol.31
, pp. 398-403
-
-
Jinno, H.1
Tanaka-Kagawa, T.2
Ohno, A.3
-
32
-
-
33750592308
-
Intra- and inter-ethnic differences in the allele frequencies of cytochrome P450 2116 gene in Chinese
-
Guan S, Huang M, Li X, Chen X, Chan E, Zhou SF: Intra- and inter-ethnic differences in the allele frequencies of cytochrome P450 2116 gene in Chinese. Pharm. Res. 23, 1983-1990 (2006).
-
(2006)
Pharm. Res
, vol.23
, pp. 1983-1990
-
-
Guan, S.1
Huang, M.2
Li, X.3
Chen, X.4
Chan, E.5
Zhou, S.F.6
-
33
-
-
8244249473
-
Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele
-
Xiao ZS, Goldstein JA, Xie HG et al.: Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele. J. Pharmacol. Exp. Ther. 281, 604-609 (1997).
-
(1997)
J. Pharmacol. Exp. Ther
, vol.281
, pp. 604-609
-
-
Xiao, Z.S.1
Goldstein, J.A.2
Xie, H.G.3
-
34
-
-
0027965620
-
Genetic analysis of the Chinese cytochrome P4502D locus: Characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation
-
Johansson I, Oscarson M, Yue QY, Bertilsson L, Sjoqvist F, Ingelman-Sundberg M: Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation. Mol. Pharmacol. 46, 452-459 (1994).
-
(1994)
Mol. Pharmacol
, vol.46
, pp. 452-459
-
-
Johansson, I.1
Oscarson, M.2
Yue, Q.Y.3
Bertilsson, L.4
Sjoqvist, F.5
Ingelman-Sundberg, M.6
|