-
1
-
-
0026518073
-
Antithrombotic therapy in deep vein thrombosis and pulmonary embolism
-
Hirsh, J. Antithrombotic therapy in deep vein thrombosis and pulmonary embolism. Am. Heart J. 123, 1115-1122 (1992).
-
(1992)
Am. Heart J
, vol.123
, pp. 1115-1122
-
-
Hirsh, J.1
-
2
-
-
0035128503
-
Oral anticoagulants: Mechanism of action, clinical effectiveness, and optimal therapeutic range
-
Hirsh, J. et al. Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest 119 (suppl. 1), 8S-21S (2001).
-
(2001)
Chest
, vol.119
, Issue.SUPPL. 1
-
-
Hirsh, J.1
-
3
-
-
0028785453
-
Antithrombotic therapy in atrial fibrillation
-
Laupacis, A. et al. Antithrombotic therapy in atrial fibrillation. Chest 108, 352S-359S (1995).
-
(1995)
Chest
, vol.108
-
-
Laupacis, A.1
-
4
-
-
0028876997
-
Antithrombotic therapy in patients with mechanical and biological prosthetic heart valves
-
Stein, P.D. et al. Antithrombotic therapy in patients with mechanical and biological prosthetic heart valves. Chest 108, 371S-379S (1995).
-
(1995)
Chest
, vol.108
-
-
Stein, P.D.1
-
5
-
-
17944366735
-
Interindividual variability in sensitivity to warfarin - nature or nurture?
-
Loebstein, R. et al. Interindividual variability in sensitivity to warfarin - nature or nurture? Clin. Pharmacol. Ther. 70, 159-164 (2001).
-
(2001)
Clin. Pharmacol. Ther
, vol.70
, pp. 159-164
-
-
Loebstein, R.1
-
6
-
-
0037374422
-
Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patients
-
Takahashi, H. et al. Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patients. Clin. Pharmacol. Ther. 73, 253-263 (2003).
-
(2003)
Clin. Pharmacol. Ther
, vol.73
, pp. 253-263
-
-
Takahashi, H.1
-
7
-
-
4544288090
-
Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose
-
Zhao, F. et al. Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose. Clin. Pharmacol. Ther. 76, 210-219 (2004).
-
(2004)
Clin. Pharmacol. Ther
, vol.76
, pp. 210-219
-
-
Zhao, F.1
-
8
-
-
0021872842
-
Anticoagulant-induced intracerebral bleeding in brain ischemia. Evaluation in 200 patients with TIAs, emboli from the heart, and progressing stroke
-
Bogousslavsky, J. & Regli, F. Anticoagulant-induced intracerebral bleeding in brain ischemia. Evaluation in 200 patients with TIAs, emboli from the heart, and progressing stroke. Acta Neurol. Scand. 71, 464-471 (1985).
-
(1985)
Acta Neurol. Scand
, vol.71
, pp. 464-471
-
-
Bogousslavsky, J.1
Regli, F.2
-
9
-
-
0003005833
-
Bleeding complications to long-term oral anticoagulant therapy
-
Gullov, A.L., Koefoed, B.G. & Petersen, P. Bleeding complications to long-term oral anticoagulant therapy. J. Thromb. Thrombolysis 1, 17-25 (1994).
-
(1994)
J. Thromb. Thrombolysis
, vol.1
, pp. 17-25
-
-
Gullov, A.L.1
Koefoed, B.G.2
Petersen, P.3
-
10
-
-
0027257511
-
Anticoagulant-related bleeding: Clinical epidemiology, prediction, and prevention
-
Landefeld, C.S. & Beyth, R.J. Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention. Am. J. Med. 95, 315-328 (1993).
-
(1993)
Am. J. Med
, vol.95
, pp. 315-328
-
-
Landefeld, C.S.1
Beyth, R.J.2
-
11
-
-
0031841377
-
Cytochrome P4502C9: An enzyme of major importance in human drug metabolism
-
Miners, J.O. & Birkett, D.J. Cytochrome P4502C9: an enzyme of major importance in human drug metabolism. Br. J. Clin. Pharmacol. 45, 525-538 (1998).
-
(1998)
Br. J. Clin. Pharmacol
, vol.45
, pp. 525-538
-
-
Miners, J.O.1
Birkett, D.J.2
-
12
-
-
0026519541
-
Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: A role for P-4502C9 in the etiology of (S)-warfarin-drug interactions
-
Rettie, A.E. et al. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions. Chem. Res. Toxicol. 5, 54-59 (1992).
-
(1992)
Chem. Res. Toxicol
, vol.5
, pp. 54-59
-
-
Rettie, A.E.1
-
13
-
-
0034872136
-
Pharmacogenetics of warfarin elimination and its clinical implications
-
Takahashi, H. & Echizen, H. Pharmacogenetics of warfarin elimination and its clinical implications. Clin. Pharmacokinet. 40, 587-603 (2001).
-
(2001)
Clin. Pharmacokinet
, vol.40
, pp. 587-603
-
-
Takahashi, H.1
Echizen, H.2
-
14
-
-
0029564238
-
Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy
-
Furuya, H. et al. Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy. Pharmacogenetics 5, 389-392 (1995).
-
(1995)
Pharmacogenetics
, vol.5
, pp. 389-392
-
-
Furuya, H.1
-
15
-
-
0030868490
-
Genetic analysis of CYP2C9 polymorphism in a Japanese population
-
Nasu, K., Kubota, T. & Ishizaki, T. Genetic analysis of CYP2C9 polymorphism in a Japanese population. Pharmacogenetics 7, 405-409 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 405-409
-
-
Nasu, K.1
Kubota, T.2
Ishizaki, T.3
-
16
-
-
0037131892
-
CYP2C9 allelic variants: Ethnic distribution and functional significance
-
Xie, H.G., Prasad, H.C., Kim, R.B. & Stein, C.M. CYP2C9 allelic variants: ethnic distribution and functional significance. Adv. Drug Deliv. Rev. 54, 1257-1270 (2002).
-
(2002)
Adv. Drug Deliv. Rev
, vol.54
, pp. 1257-1270
-
-
Xie, H.G.1
Prasad, H.C.2
Kim, R.B.3
Stein, C.M.4
-
17
-
-
0015494743
-
Warfarin and the inhibition of vitamin K activity by an oxide metabolite
-
Bell, R.G. & Matschiner, J.T. Warfarin and the inhibition of vitamin K activity by an oxide metabolite. Nature 237, 32-33 (1972).
-
(1972)
Nature
, vol.237
, pp. 32-33
-
-
Bell, R.G.1
Matschiner, J.T.2
-
18
-
-
0022405539
-
Vitamin K-dependent carboxylation and vitamin K metabolism in liver. Effects of warfarin
-
Wallin, R. & Martin, L.F. Vitamin K-dependent carboxylation and vitamin K metabolism in liver. Effects of warfarin. J. Clin. Invest. 76, 1879-1884 (1985).
-
(1985)
J. Clin. Invest
, vol.76
, pp. 1879-1884
-
-
Wallin, R.1
Martin, L.F.2
-
19
-
-
24944503322
-
A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity
-
Yuan, H.Y. et al. A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity. Hum. Mol. Genet. 14, 1745-1751 (2005).
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 1745-1751
-
-
Yuan, H.Y.1
-
20
-
-
22044433685
-
Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity
-
Bodin, L. et al. Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity. Blood 106, 135-140 (2005).
-
(2005)
Blood
, vol.106
, pp. 135-140
-
-
Bodin, L.1
-
21
-
-
33746765022
-
VKORC1 gene variations are the major contributors of variation in warfarin dose in Japanese patients
-
Obayashi, K. et al. VKORC1 gene variations are the major contributors of variation in warfarin dose in Japanese patients. Clin. Pharmacol. Ther. 80, 169-178 (2006).
-
(2006)
Clin. Pharmacol. Ther
, vol.80
, pp. 169-178
-
-
Obayashi, K.1
-
22
-
-
21144448879
-
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
-
Rieder, M.J. et al. Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. N. Engl. J. Med. 352, 2285-2293 (2005).
-
(2005)
N. Engl. J. Med
, vol.352
, pp. 2285-2293
-
-
Rieder, M.J.1
-
23
-
-
27744485315
-
A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical data
-
Hillman, M.A. et al. A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical data. Clin. Med. Res. 3, 137-145 (2005).
-
(2005)
Clin. Med. Res
, vol.3
, pp. 137-145
-
-
Hillman, M.A.1
-
24
-
-
20144387370
-
Prospective dosing of warfarin based on cytochrome P-450 2C9 genotype
-
Voora, D. et al. Prospective dosing of warfarin based on cytochrome P-450 2C9 genotype. Thromb. Haemost. 93, 700-705 (2005).
-
(2005)
Thromb. Haemost
, vol.93
, pp. 700-705
-
-
Voora, D.1
-
25
-
-
11244332058
-
A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin
-
D'Andrea, G. et al. A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin. Blood 105, 645-649 (2005).
-
(2005)
Blood
, vol.105
, pp. 645-649
-
-
D'Andrea, G.1
-
26
-
-
23044440450
-
The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: Proposal for a new dosing regimen
-
Sconce, E.A. et al. The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen. Blood 106, 2329-2333 (2005).
-
(2005)
Blood
, vol.106
, pp. 2329-2333
-
-
Sconce, E.A.1
-
27
-
-
31344451857
-
Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans
-
Takahashi, H. et al. Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans. Pharmacogenet. Genomics 16, 101-110 (2006).
-
(2006)
Pharmacogenet. Genomics
, vol.16
, pp. 101-110
-
-
Takahashi, H.1
-
28
-
-
34548822941
-
Genetic-based dosing in orthopaedic patients beginning warfarin therapy
-
Millican, E. et al. Genetic-based dosing in orthopaedic patients beginning warfarin therapy. Blood 110, 1511-1515 (2007).
-
(2007)
Blood
, vol.110
, pp. 1511-1515
-
-
Millican, E.1
-
29
-
-
34247141066
-
Warfarin dose and the pharmacogenomics of CYP2C9 and VKORC1 - rationale and perspectives
-
Yin, T. & Miyata, T. Warfarin dose and the pharmacogenomics of CYP2C9 and VKORC1 - rationale and perspectives. Thromb. Res. 120, 1-10 (2007).
-
(2007)
Thromb. Res
, vol.120
, pp. 1-10
-
-
Yin, T.1
Miyata, T.2
-
30
-
-
0037012465
-
Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy
-
Higashi, M.K. et al. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAMA 287, 1690-1698 (2002).
-
(2002)
JAMA
, vol.287
, pp. 1690-1698
-
-
Higashi, M.K.1
-
31
-
-
0034619505
-
A multicomponent intervention to prevent major bleeding complications in older patients receiving warfarin. A randomized, controlled trial
-
Beyth, R.J., Quinn, L. & Landefeld, C.S. A multicomponent intervention to prevent major bleeding complications in older patients receiving warfarin. A randomized, controlled trial. Ann. Intern. Med. 133, 687-95 (2000).
-
(2000)
Ann. Intern. Med
, vol.133
, pp. 687-695
-
-
Beyth, R.J.1
Quinn, L.2
Landefeld, C.S.3
-
32
-
-
0028840258
-
Hemorrhagic complications of anticoagulant treatment
-
Levine, M.N., Raskob, G., Landefeld, S. & Hirsh, J. Hemorrhagic complications of anticoagulant treatment. Chest 108, 276S-290S (1995).
-
(1995)
Chest
, vol.108
-
-
Levine, M.N.1
Raskob, G.2
Landefeld, S.3
Hirsh, J.4
-
33
-
-
33646459330
-
The influence of sequence variations in factor VII, gamma-glutamyl carboxylase and vitamin K epoxide reductase complex genes on warfarin dose requirement
-
Herman, D., Peternel, P., Stegnar, M., Breskvar, K. & Dolzan, V. The influence of sequence variations in factor VII, gamma-glutamyl carboxylase and vitamin K epoxide reductase complex genes on warfarin dose requirement. Thromb. Haemost. 95, 782-787 (2006).
-
(2006)
Thromb. Haemost
, vol.95
, pp. 782-787
-
-
Herman, D.1
Peternel, P.2
Stegnar, M.3
Breskvar, K.4
Dolzan, V.5
-
34
-
-
33746211654
-
APOE genotype makes a small contribution to warfarin dose requirements
-
Sconce, E.A., Daly, A.K., Khan, T.I., Wynne, H.A. & Kamali, F. APOE genotype makes a small contribution to warfarin dose requirements. Pharmacogenet. Genomics 16, 609-611 (2006).
-
(2006)
Pharmacogenet. Genomics
, vol.16
, pp. 609-611
-
-
Sconce, E.A.1
Daly, A.K.2
Khan, T.I.3
Wynne, H.A.4
Kamali, F.5
-
35
-
-
33645547905
-
Combined genetic profiles of components and regulators of the vitamin K-dependent gamma-carboxylation system affect individual sensitivity to warfarin
-
Vecsler, M. et al. Combined genetic profiles of components and regulators of the vitamin K-dependent gamma-carboxylation system affect individual sensitivity to warfarin. Thromb. Haemost. 95, 205-211 (2006).
-
(2006)
Thromb. Haemost
, vol.95
, pp. 205-211
-
-
Vecsler, M.1
-
36
-
-
23644437525
-
Common VKORC1 and GGCX polymorphisms associated with warfarin dose
-
Wadelius, M. et al. Common VKORC1 and GGCX polymorphisms associated with warfarin dose. Pharmacogenomics J. 5, 262-270 (2005).
-
(2005)
Pharmacogenomics J
, vol.5
, pp. 262-270
-
-
Wadelius, M.1
-
37
-
-
33947227273
-
Association of warfarin dose with genes involved in its action and metabolism
-
Wadelius, M. et al. Association of warfarin dose with genes involved in its action and metabolism. Hum. Genet. 121, 23-34 (2007).
-
(2007)
Hum. Genet
, vol.121
, pp. 23-34
-
-
Wadelius, M.1
-
38
-
-
0029658591
-
The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism
-
Sullivan-Klose, T.H. et al. The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism. Pharmacogenetics 6, 341-349 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 341-349
-
-
Sullivan-Klose, T.H.1
|