Mental arithmetic leads to multiple discrete changes from baseline in the firing patterns of human thalamic neurons

Journal of Neurophysiology

Volumn 101, Issue 4, 2009, Pages 2107-2119

  Kim, J H ^a   Ohara, S ^a   Lenz, F A ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARITHMETIC; ARTICLE; BRAIN NERVE CELL; HUMAN; HUMAN TISSUE; INHIBITORY POSTSYNAPTIC POTENTIAL; NERVE CELL MEMBRANE POTENTIAL; PRIORITY JOURNAL; SPIKE WAVE; THALAMUS;

ACTION POTENTIALS; ADULT; AGED; BRAIN MAPPING; DEEP BRAIN STIMULATION; ESSENTIAL TREMOR; FEMALE; HUMANS; MALE; MATHEMATICS; MENTAL PROCESSES; MIDDLE AGED; NEURONS; RETROSPECTIVE STUDIES; THALAMUS; TIME FACTORS;

EID: 65649113480     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.91087.2008     Document Type: Article

References (56)

1. Ahlsen G, Grant K, Lindstrom S. Monosynaptic excitation of principal cells in the lateral geniculate nucleus by corticofugal fibers. Brain Res 234: 454-458, 1982. (Pubitemid 12175912)
2. Andersen P, Sears TA. The role of inhibition in the phasing of spontaneous thalamocortical discharge. J Physiol 173: 459-480, 1964.
3. Bal T, von Krosigk M, McCormick DA. Role of the ferret perigeniculate nucleus in the generation of synchronized oscillations in vitro. J Physiol 483: 665-685, 1995a.
4. Bal T, von Krosigk M, McCormick DA. Synaptic and membrane mechanisms underlying synchronized oscillations in the ferret lateral geniculate nucleus in vitro. J Physiol 483: 641-663,1995b.
5. Beierlein M, Fall CP, Rinzel J, Yuste R. Thalamocortical bursts trigger recurrent activity in neocortical networks: layer 4 as a frequency-dependent gate. J Neurosci 22: 9885-9894, 2002. (Pubitemid 35332873)
6. Bezdudnaya T, Cano M, Bereshpolova Y, Stoelzel CR, Alonso JM, Swadlow HA. Thalamic burst mode and inattention in the awake LGNd. Neuron 49: 421-432, 2006. (Pubitemid 43152243)
7. Contreras D, Steriade M. Cellular basis of EEG slow rhythms: a study of dynamic corticothalamic relationships. J Neurosci 15: 604-622, 1995.
8. Cox DR, Lewis PAW. The Statistical Analysis of Series of Events. London: Chapman & Hall, 1966.
9. Debay D, Wolfart J, Le FY, Le MG, Bal T. Exploring spike transfer through the thalamus using hybrid artificial-biological neuronal networks. J Physiol (Paris) 98: 540-558, 2004. (Pubitemid 41751003)
10. Deuschl G, Bain P, Brin M, Ad Hoc Scientific Committee. Consensus statement of the Movement Disorder Society on Tremor. Mov Disord 13, Suppl. 3: 2-23, 1998. (Pubitemid 28517753)
11. Domich L, Oakson G, Steriade M. Thalamic burst patterns in the naturally sleeping cat: a comparison between cortically-projecting and reticularis neurones. J Physiol 379: 429-449, 1986.
12. Garonzik IM, Hua SE, Ohara S, Lenz FA. Intraoperative microelectrode and semi-microelectrode recording during the physiological localization of the thalamic nucleus ventral intermediate. Mov Disord 17, Suppl. 3: S135-S144, 2002. (Pubitemid 36040917)
13. Guido W, Lu SM, Vaughan JW, Godwin DW, Sherman SM. Receiver operating characteristic (ROC) analysis of neurons in the cat's lateral geniculate nucleus during tonic and burst response mode. Vis Neurosci 12: 723-741, 1995.
14. Jahnsen H, Llinás R. Ionic basis for the electro-responsiveness and oscillatory properties of guinea-pig thalamic neurones in vitro. J Physiol 349: 227-247, 1984.
15. Jankovic J. Essential tremor: a heterogenous disorder. Mov Disord 17: 638-644, 2002. (Pubitemid 41295001)
16. Jeanmonod D, Magnin M, Morel A. Low-threshold calcium spike bursts in the human thalamus. Common physiopathology for sensory, motor and limbic positive symptoms. Brain 119: 363-375, 1996. (Pubitemid 26149355)
17. Koller WC, Lyons KE, Wilkinson SB, Troster AI, Pahwa R. Long-term safety and efficacy of unilateral deep brain stimulation of the thalamus in essential tremor. Mov Disord 16: 464-468, 2001.
18. Lee JI, Ohara S, Dougherty PM, Lenz FA. Pain and temperature encoding in the human thalamic somatic sensory nucleus (ventral caudal): inhibition-related bursting evoked by somatic stimuli. J Neurophysiol 94: 1676-1687, 2005. (Pubitemid 41192841)
19. Lee JI, Verhagen ML, Ohara S, Dougherty PM, Kim JH, Lenz FA. Internal pallidal neuronal activity during mild drug-related dyskinesias in Parkinson's disease: decreased firing rates and altered firing patterns. J Neurophysiol 97: 2627-2641, 2007. (Pubitemid 46557697)
20. Lenz FA, Dostrovsky JO, Tasker RR, Yamashiro K, Kwan HC, Murphy JT. Single-unit analysis of the human ventral thalamic nuclear group: somatosensory responses. J Neurophysiol 59: 299-316, 1988a. (Pubitemid 18069310)
21. Lenz FA, Garonzik IM, Zirh TA, Dougherty PM. Neuronal activity in the region of the thalamic principal sensory nucleus (ventralis caudalis) in patients with pain following amputations. Neuroscience 86: 1065-1081, 1998. (Pubitemid 28318533)
22. Lenz FA, Kwan HC, Martin R, Tasker R, Richardson RT, Dostrovsky JO. Characteristics of somatotopic organization and spontaneous neuronal activity in the region of the thalamic principal sensory nucleus in patients with spinal cord transection. J Neurophysiol 72: 1570-1587, 1994. (Pubitemid 24325087)
23. Lenz FA, Normand SL, Kwan HC, Andrews D, Rowland LH, Jones MW, Seike M, Lin YC, Tasker RR, Dostrovsky JO. Statistical prediction of the optimal site for thalamotomy in parkinsonian tremor. Mov Disord 10: 318-328, 1995.
24. Lenz FA, Ohara S, Gracely RH, Dougherty PM, Patel SH. Pain encoding in the human forebrain: binary and analog exteroceptive channels. J Neurosci 24: 6540-6544, 2004. (Pubitemid 38971702)
25. Lenz FA, Seike M, Richardson RT, Lin YC, Baker FH, Khoja I, Jaeger CJ, Gracely RH. Thermal and pain sensations evoked by microstimulation in the area of human ventrocaudal nucleus. J Neurophysiol 70: 200-212, 1993. (Pubitemid 23220309)
26. Lenz FA, Tasker RR, Kwan HC, Schnider S, Kwong R, Murayama Y, Dostrovsky JO, Murphy JT. Single unit analysis of the human ventral thalamic nuclear group: correlation of thalamic "tremor cells" with the 3-6 Hz component of parkinsonian tremor. J Neurosci 8: 754-764, 1988b.
27. 2+ current by ATP at resting membrane potential. J Neurosci 24: 5592-5602, 2004.
28. Lezak MD. Neuropsychological Assessment. New York: Oxford Univ. Press, 1995.
29. Liu XB, Honda CN, Jones EG. Distribution of four types of synapse on physiologically identified relay neurons in the ventral posterior thalamic nucleus of the cat. J Comp Neurol 352: 69-91, 1995.
30. Lu SM, Guido W, Sherman SM. Effects of membrane voltage on receptive field properties of lateral geniculate neurons in the cat: contributions of the low-threshold Ca2+ conductance. J Neurophysiol 68: 2185-2198, 1992. (Pubitemid 23015518)
31. Martinez-Conde S, Macknik SL, Hubel DH. Microsaccadic eye movements and firing of single cells in the striate cortex of macaque monkeys. Nat Neurosci 3: 251-258, 2000. (Pubitemid 30140787)
32. Martinez-Conde S, Macknik SL, Hubel DH. The function of bursts of spikes during visual fixation in the awake primate lateral geniculate nucleus and primary visual cortex. Proc Natl Acad Sci USA 99: 13920-13925, 2002. (Pubitemid 35215481)
33. McCarley RW, Benoit O, Barrionuevo G. Lateral geniculate nucleus unitary discharge in sleep and waking: state and rate specific aspects. J Neurophysiol 50: 798-818, 1983.
34. Ohara S, Lenz FA. Medial lateral extent of thermal and pain sensations evoked by microstimulation in somatic sensory nuclei of human thalamus. J Neurophysiol 90: 2367-2377, 2003. (Pubitemid 37266505)
35. Ohara S, Taghva A, Kim JH, Lenz FA. Spontaneous low threshold spike bursting in awake humans is different in different lateral thalamic nuclei. Exp Brain Res 180: 280-281, 2007.
36. Patel S, Ohara S, Dougherty PM, Gracely RH, Lenz FA. Psychophysical elements of place and modality specificity in the thalamic somatic sensory nucleus (ventral caudal, vc) of awake humans. J Neurophysiol 95: 646-659, 2006.
37. Radhakrishnan V, Tsoukatos J, Davis KD, Tasker RR, Lozano AM, Dostrovsky JO. A comparison of the burst activity of lateral thalamic neurons in chronic pain and non-pain patients. Pain 80: 567-575, 1999. (Pubitemid 29182706)
38. Ramcharan EJ, Cox CL, Zhan XJ, Sherman SM, Gnadt JW. Cellular mechanisms underlying activity patterns in the monkey thalamus during visual behavior. J Neurophysiol 84: 1982-1987, 2000a.
39. Ramcharan EJ, Gnadt JW, Sherman SM. State dependent changes in the firing pattern of relay neurons in the monkey LGN. Soc Neurosci Abstr 24: 139, 1998.
40. Ramcharan EJ, Gnadt JW, Sherman SM. Burst and tonic firing in thalamic cells of unanesthetized, behaving monkeys. Vis Neurosci 17: 55-62, 2000b. (Pubitemid 30167553)
41. Ramcharan EJ, Gnadt JW, Sherman SM. The effects of saccadic eye movements on the activity of geniculate relay neurons in the monkey. Vis Neurosci 18: 253-258, 2001.
42. Ramcharan EJ, Gnadt JW, Sherman SM. Higher-order thalamic relays burst more than first-order relays. Proc Natl Acad Sci USA 102: 12236-12241, 2005.
43. Roy JP, Clercq M, Steriade M, Deschenes M. Electrophysiology of neurons of lateral thalamic nuclei in cat: mechanisms of long-lasting hyperpolarizations. J Neurophysiol 51: 1220-1235, 1984. (Pubitemid 14076769)
44. Schaltenbrand G, Bailey P. Introduction to Stereotaxis with an Atlas of the Human Brain. Stuttgart, Germany: Thieme, 1959.
45. Schwarz G. Estimating the dimension of a model. Anal Stat 6: 461-464, 1978.
46. Sherman SM, Guillery RW. Exploring the Thalamus and Its Role in Cortical Function. New York: Oxford Univ. Press, 2001.
47. Smith GD, Sherman SM. Detectability of excitatory versus inhibitory drive in an integrate-and-fire-or-burst thalamocortical relay neuron model. J Neurosci 22: 10242-10250, 2002. (Pubitemid 35416863)
48. Snedecor GW, Cochran WG. Statistical Methods. Ames, IA: Iowa State Univ. Press, 1967.
49. Soltesz I, Lightowler S, Leresche N, Crunelli V. On the properties and origin of the GABAB inhibitory postsynaptic potential recorded in morphologically identified projection cells of the cat dorsal lateral geniculate nucleus. Neuroscience 33: 23-33, 1989. (Pubitemid 20032972)
50. Steriade M, Jones EG, Llinás RR. Thalamic Oscillations and Signaling. New York: Wiley, 1990.
51. Steriade M, Jones EG, McCormick DA. Thalamic, organization and chemical neuroanatomy. In: Thalamus. Amsterdam: Elsevier, 1997a, vol.1, p. 269-338.
52. Steriade M, Jones EG, McCormick DA. Thalamus Organisation and Function. Amsterdam: Elsevier, 1997b.
53. Swadlow HA, Gusev AG. The impact of "bursting" thalamic impulses at a neocortical synapse. Nat Neurosci 4: 402-408, 2001.
54. Weingessel A, Dimitriadou A, Dolnicar S. An Examination of Indexes for Determining the Number of Clusters in Binary Data Sets (Working Paper Series No. 29). Vienna, Austria: Vienna Univ. of Economics and Business Administration, 1999, p. 1-19.
55. Wolfart J, Debay D, Le MG, Destexhe A, Bal T. Synaptic background activity controls spike transfer from thalamus to cortex. Nat Neurosci 8: 1760-1767, 2005. (Pubitemid 41683205)
56. Zirh AT, Lenz FA, Reich SG, Dougherty PM. Patterns of bursting occurring in thalamic cells during parkinsonian tremor. Neuroscience 83: 107-121, 1997.