Study on the pharmacokinetics drug-drug interaction potential of Glycyrrhiza uralensis, a traditional Chinese medicine, with lidocaine in rats

Phytotherapy Research

Volumn 23, Issue 5, 2009, Pages 603-607

  Tang, Jingcheng ^a   Song, Xiaohong ^a   Zhu, Min ^b   Zhang, Jinnan ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Glycyrrhiza uralensis; Hepatic enzyme induction; Herb drug interaction; Herbal medicine; Lidocaine; P450 isozymes

Indexed keywords

CYTOCHROME P450; GLYCYRRHIZA URALENSIS EXTRACT; ISOENZYME; LIDOCAINE; PROTEIN; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE INCREASE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG URINE LEVEL; ENZYME INDUCTION; LIVER MICROSOME; MALE; MAXIMUM PLASMA CONCENTRATION; METABOLIC RATE; NONHUMAN; RAT; TRADITIONAL MEDICINE; ANIMAL; BLOOD; CHEMISTRY; DRUG EFFECT; GLYCYRRHIZA URALENSIS; HERB DRUG INTERACTION; METABOLISM; SPRAGUE DAWLEY RAT; URINE;

GLYCYRRHIZA URALENSIS; RATTUS;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; GLYCYRRHIZA URALENSIS; HERB-DRUG INTERACTIONS; LIDOCAINE; MALE; MEDICINE, CHINESE TRADITIONAL; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY;

EID: 65649111144     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2450     Document Type: Article

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