Effect of phenobarbital on the pharmacokinetics of lidocaine, monoethylglycinexylidide and 3-hydroxylidocaine in the rat: Correlation with P450 isoform levels

Drug Metabolism and Disposition

Volumn 25, Issue 3, 1997, Pages 296-300

  Nakamoto, Tatsuo ^b   Oda, Yutaka ^a   Imaoka, Susumu ^b   Funae, Yoshihiko ^b   Fujimori, Mitsugu ^b  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYLIDOCAINE; CYTOCHROME P450; DEETHYLLIDOCAINE; LIDOCAINE; PHENOBARBITAL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG METABOLISM; EPILEPSY; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LIVER METABOLISM; LIVER MICROSOME; LOCAL ANESTHESIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANESTHETICS, LOCAL; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; ENZYME INDUCTION; HYPNOTICS AND SEDATIVES; ISOENZYMES; LIDOCAINE; MALE; MICROSOMES, LIVER; PHENOBARBITAL; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030937081     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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