메뉴 건너뛰기




Volumn 53, Issue 4, 2009, Pages 1581-1585

High cerebrospinal fluid (CSF) penetration and potent bactericidal activity in CSF of NZ2114, a novel plectasin variant, during experimental pneumococcal meningitis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CEFTRIAXONE; NZ 2114; PENICILLIN G; UNCLASSIFIED DRUG;

EID: 65649097699     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01202-08     Document Type: Article
Times cited : (37)

References (13)
  • 1
    • 34548855054 scopus 로고    scopus 로고
    • Streptococcus penumoniae meningitis. Clinical and experimental studies
    • Andersen, C. O. 2007. Streptococcus penumoniae meningitis. Clinical and experimental studies. Dan. Med. Bull. 54:189-209.
    • (2007) Dan. Med. Bull. , vol.54 , pp. 189-209
    • Andersen, C.O.1
  • 2
    • 0032770616 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of antibiotics in meningitis
    • DOI 10.1016/S0891-5520(05)70096-9
    • Andes, D. R., and W. A. Craig. 1999. Pharmacokinetics and pharmacodynamics of antibiotics in meningitis. Infect. Dis. Clin. N. Am. 13:595-618. (Pubitemid 29398576)
    • (1999) Infectious Disease Clinics of North America , vol.13 , Issue.3 , pp. 595-618
    • Andes, D.R.1    Craig, W.A.2
  • 3
    • 0030296762 scopus 로고    scopus 로고
    • Passage of peptides across the blood-brain barrier: Pathophysiological perspectives
    • DOI 10.1016/S0024-3205(96)00380-3, PII S0024320596003803
    • Banks, W. A., and A. J. Kastin. 1996. Passage of peptides across the blood-brain barrier: pathophysiological perspectives. Life Sci. 59:1923-1943. (Pubitemid 26390194)
    • (1996) Life Sciences , vol.59 , Issue.23 , pp. 1923-1943
    • Banks, W.A.1    Kastin, A.J.2
  • 4
    • 0024570193 scopus 로고
    • Delayed cerebrospinal fluid sterilization and adverse outcome of bacterial meningitis in infants and children
    • Lebel, M. H., and G. H. McCracken, Jr. 1989. Delayed cerebrospinal fluid sterilization and adverse outcome of bacterial meningitis in infants and children. Pediatrics 83:161-167. (Pubitemid 19048681)
    • (1989) Pediatrics , vol.83 , Issue.2 , pp. 161-167
    • Lebel, M.H.1    McCracken Jr., G.H.2
  • 6
    • 0031028767 scopus 로고    scopus 로고
    • Antimicrobial susceptibility of Bordetella bronchiseptica isolates from cats and a comparison of the agar dilution and E-test methods
    • DOI 10.1016/S0378-1135(96)01256-4, PII S0378113596012564
    • National Committee for Clinical Laboratory Standards. 1997. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 4th ed.; Approved standard, p.10-13. NCCLS document M7-A4. National Committee for Clinical Laboratory Standards, Wayne, PA. (Pubitemid 27099523)
    • (1997) Veterinary Microbiology , vol.54 , Issue.1 , pp. 63-72
    • Speakman, A.J.1    Binns, S.H.2    Dawson, S.3    Hart, C.A.4    Gaskell, R.M.5
  • 7
    • 0028219680 scopus 로고
    • Lipophilicity at pH 7.4 and molecular size govern the entry of the free serum fraction of drugs into the cerebrospinal fluid in humans with uninflamed meninges
    • DOI 10.1016/0022-510X(94)90052-3
    • Nau, R., F. Sorgel, and H. W. Prange. 1994. Lipophilicity at pH 7.4 and molecular size govern the entry of the free serum fraction of drugs into the cerebrospinal fluid in humans with uninflamed meninges. J. Neurol. Sci. 122:61-65. (Pubitemid 24073751)
    • (1994) Journal of the Neurological Sciences , vol.122 , Issue.1 , pp. 61-65
    • Nau, R.1    Sorgel, F.2    Prange, H.W.3
  • 8
    • 27744593376 scopus 로고    scopus 로고
    • Clinical presentation and prognostic factors of Streptococcus pneumoniae meningitis according to the focus of infection
    • DOI 10.1186/1471-2334-5-93
    • Østergaard, C, H. B. Konradsen, and S. Samuelsson. 2005. Clinical presentation and prognostic factors of Streptococcus pneumoniae meningitis according the focus of infection. BMC Infect. Dis. 5:1-11. (Pubitemid 41614807)
    • (2005) BMC Infectious Diseases , vol.5 , pp. 93
    • Ostergaard, C.1    Konradsen, H.B.2    Samuelsson, S.3
  • 9
    • 0031807605 scopus 로고    scopus 로고
    • Evaluation of moxifloxacin, a new 8-methoxyquinolone, for treatment of meningitis caused by a penicillin-resistant pneumococcus in rabbits
    • Østergaard, C, T. K. Sorensen, J. D. Knudsen, and N. Frimodt-Meller. 1998. Evaluation of moxifloxacin, a new 8-methoxyquinolone, for treatment of meningitis caused by a penicillin-resistant pneumococcus in rabbits. Antimicrob. Agents Chemother. 42:1706-1712. (Pubitemid 28311566)
    • (1998) Antimicrobial Agents and Chemotherapy , vol.42 , Issue.7 , pp. 1706-1712
    • Ostergaard, C.1    Sorensen, T.K.2    Knudsen, J.D.3    Frimodt-Moller, N.4
  • 11
    • 33846664095 scopus 로고    scopus 로고
    • Synthesis, characterization and in vitro antibacterial activity of new steroidal thiazolo quinoxalines
    • DOI 10.1016/j.ejmech.2006.07.006, PII S0223523406002650
    • Sandvang, D., P. H. Mygind, M. E. Jones, D. F. Sahm, and H.-H. Kristensen. 2007. In vitro activity and characterization of NZ2114, an improved variant of plectasin, abstr. Fl-1663. Abstr. 47th Intersci. Conf. Antimicrob. Agents Chemother. (Pubitemid 46198983)
    • (2007) European Journal of Medicinal Chemistry , vol.42 , Issue.1 , pp. 103-108
    • Khan, S.A.1    Saleem, K.2    Khan, Z.3
  • 13
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • DOI 10.1038/415389a
    • Zasloff, M. 2002. Antimicrobial peptides of multicellular organisms. Nature 415:389-395. (Pubitemid 34100944)
    • (2002) Nature , vol.415 , Issue.6870 , pp. 389-395
    • Zasloff, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.