Gene expression profiling of leukemia stem cells

Methods in Molecular Biology

Volumn 538, Issue , 2009, Pages 231-246

  Krivtsov, Andrei V ^a   Wang, Yingzi ^a   Feng, Zhaohui ^a   Armstrong, Scott A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Gene expression; Gene expression profiling; Leukemia; Leukemia stem cells; Microarray; MLL AF9; RNA amplification; Stem cells

Indexed keywords

MESSENGER RNA; MIXED LINEAGE LEUKEMIA PROTEIN; MLL AF9 FUSION PROTEIN, HUMAN; MLL-AF9 FUSION PROTEIN, HUMAN; ONCOPROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL; ARTICLE; C57BL MOUSE; CANCER STEM CELL; COLONY FORMING UNIT GM; DNA MICROARRAY; EXPERIMENTAL LEUKEMIA; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; METHODOLOGY; MOUSE; PATHOLOGY; TRANSPLANTATION;

ANIMALS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GRANULOCYTE-MACROPHAGE PROGENITOR CELLS; LEUKEMIA, EXPERIMENTAL; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, INBRED C57BL; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NEOPLASTIC STEM CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENE PROTEINS, FUSION; RNA, MESSENGER;

EID: 65649094837     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-418-6_11     Document Type: Article

References (11)

1. Krivtsov AV, Twomey D, Feng Z, et al. (2006) Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 442 (7104): 818-22. (Pubitemid 44258912)
2. Na Nakorn T, Traver D, Weissman IL, Akashi K. (2002) Myeloerythroid- restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J Clin Invest 109 (12): 1579-85. (Pubitemid 34663520)
3. Cozzio A, Passegue E, Ayton PM, Karsunky H, Cleary ML, Weissman IL. (2003) Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev 17 (24): 3029-35. (Pubitemid 38040767)
4. Akashi K, Traver D, Miyamoto T, Weissman IL. (2000) A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404 (6774): 193-7. (Pubitemid 30154488)
5. Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strobber W. (1994) Current protocols in immunology, isolation of murine macrophages. New York: Wiley
6. Eisen MB, Spellman PT, Brown PO, Botstein D. (1998) Cluster analysis and display of genome- wide expression patterns. Proc Natl Acad Sci U S A 95 (25): 14863-8. (Pubitemid 29003722)
7. Golub TR, Slonim DK, Tamayo P, et al. 1999 Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286 (5439): 531-7.
8. Tamayo P, Scanfeld D, Ebert BL, Gillette MA, Roberts CW, Mesirov JP. Metagene projection for cross-platform, cross-species characterization of global transcriptional states. Proc Natl Acad Sci U S A 2007; 104 (14): 5959-64. (Pubitemid 47175641)
9. Reich M, Liefeld T, Gould J, Lerner J, Tamayo P, Mesirov JP. (2006) GenePattern 2.0. Nat Genet 38 (5): 500-1.
10. Sanes JR, Rubenstein JL, Nicolas JF. (1986) Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J 5 (12): 3133-42.
11. Van Gelder RN, von Zastrow ME, Yool A, Dement WC, Barchas JD, Eberwine JH. (1990) Amplified RNA synthesized from limited quantities of heterogeneous cDNA. Proc Natl Acad Sci U S A 87 (5): 1663-7.